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Emamectin
Emamectin is the 4”-deoxy-4”-methylamino derivative of abamectin, a 16-membered macrocyclic lactone produced by the fermentation of the soil actinomycete ''Streptomyces avermitilis''. It is generally prepared as the salt with benzoic acid, emamectin benzoate, which is a white or faintly yellow powder. Emamectin is widely used in the US and Canada as an insecticide because of its chloride channel activation properties. History Emamectin, produced by the bacterium ''Streptomyces avermitilis'', belongs to the avermectin family of compounds all of which exhibit toxicity for nematodes, arthropods, and several other pests. The benzoate salt of emamectin in particular has found widespread use as an insecticide and is approved by the EPA for use in prevention of emerald ash borer in ash trees. Emamectin is derived from avermectin B1, also known as abamectin, a mixture of the natural avermectin B1a and B1b. Emamectin has also shown promising applications in the eradication of fish li ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sea Louse
Sea lice (singular: sea louse) are copepods (small crustaceans) of the family Caligidae within the order Siphonostomatoida. They are marine ectoparasites (external parasites) that feed on the mucus, epidermal tissue, and blood of host fish. The roughly 559 species in 37 genera include around 162 ''Lepeophtheirus'' and 268 ''Caligus'' species. The genera ''Lepeophtheirus'' and ''Caligus'' parasitize marine fish, in particular those species that have been recorded on farmed salmon. ''Lepeophtheirus salmonis'' and various ''Caligus'' species are adapted to salt water and are major ectoparasites of farmed and wild Atlantic salmon. Several antiparasitic drugs have been developed for control purposes. ''L. salmonis'' is the best understood in the areas of its biology and interactions with its salmon host. ''Caligus rogercresseyi'' has become a major parasite of concern on salmon farms in Chile. Studies are under way to gain a better understanding of the parasite and the host-parasit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Abamectin
Abamectin is a widely used insecticide and anthelmintic. Abamectin, is a member of the Avermectin family and is a natural fermentation product of soil dwelling actinomycete ''Streptomyces avermitilis''. Abamectin (also called Avermectin B1), differs from Ivermectin, the popular member of the Avermectin family, by double bond on C-22-25. Fermentation of ''Streptomyces avermitilis'' yields 8 closely related Avermectin homologues out of which B1 (a and b) forms the bulk of the fermentation. The non proprietary name, abamectin, is a combination of Bla (~ 80%) and B1b (~ 20%). Out of all the Avermectins, abamectin is the only one that is used both in agriculture and pharmaceuticals. Mode of Action Avermectins bind to the glutamate-gated chloride channels that are found in invertebrate nerve and muscle cells. They cause hyperpolarization of these cells resulting in paralysis and death. Mammals only possess glutamate-gated chloride channels in the brain and spinal cord and as the Avermec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzoate
Benzoic acid is a white (or colorless) solid organic compound with the formula , whose structure consists of a benzene ring () with a carboxyl () substituent. It is the simplest aromatic carboxylic acid. The name is derived from gum benzoin, which was for a long time its only source. Benzoic acid occurs naturally in many plants and serves as an intermediate in the biosynthesis of many secondary metabolites. Salts of benzoic acid are used as food preservatives. Benzoic acid is an important precursor for the industrial synthesis of many other organic substances. The salts and esters of benzoic acid are known as benzoates . History Benzoic acid was discovered in the sixteenth century. The dry distillation of gum benzoin was first described by Nostradamus (1556), and then by Alexius Pedemontanus (1560) and Blaise de Vigenère (1596). Justus von Liebig and Friedrich Wöhler determined the composition of benzoic acid. These latter also investigated how hippuric acid is related ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gamma Aminobutyric Acid
Gamma (uppercase , lowercase ; ''gámma'') is the third letter of the Greek alphabet. In the system of Greek numerals it has a value of 3. In Ancient Greek, the letter gamma represented a voiced velar stop . In Modern Greek, this letter represents either a voiced velar fricative or a voiced palatal fricative (while /g/ in foreign words is instead commonly transcribed as γκ). In the International Phonetic Alphabet and other modern Latin-alphabet based phonetic notations, it represents the voiced velar fricative. History The Greek letter Gamma Γ is a grapheme derived from the Phoenician letter (''gīml'') which was rotated from the right-to-left script of Canaanite to accommodate the Greek language's writing system of left-to-right. The Canaanite grapheme represented the /g/ phoneme in the Canaanite language, and as such is cognate with ''gimel'' ג of the Hebrew alphabet. Based on its name, the letter has been interpreted as an abstract representation of a camel's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Derivatives Of Emamectin (molecular Diagrams)
The derivative of a function is the rate of change of the function's output relative to its input value. Derivative may also refer to: In mathematics and economics *Brzozowski derivative in the theory of formal languages *Formal derivative, an operation on elements of a polynomial ring which mimics the form of the derivative from calculus * Radon–Nikodym derivative in measure theory *Derivative (set theory), a concept applicable to normal functions *Derivative (graph theory), an alternative term for a line graph deva *Derivative (finance), a contract whose value is derived from that of other quantities * Derivative suit or derivative action, a type of lawsuit filed by shareholders of a corporation In science and engineering *Derivative (chemistry), a type of compound which is a product of the process of derivatization *Derivative (linguistics), the process of forming a new word on the basis of an existing word, e.g. happiness and unhappy from happy *Aeroderivative gas turbine, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Onchocerciasis
Onchocerciasis, also known as river blindness, is a disease caused by infection with the parasitic worm ''Onchocerca volvulus''. Symptoms include severe itching, bumps under the skin, and blindness. It is the second-most common cause of blindness due to infection, after trachoma. The parasite worm is spread by the bites of a black fly of the ''Simulium'' type. Usually, many bites are required before infection occurs. These flies live near rivers, hence the common name of the disease. Once inside a person, the worms create larvae that make their way out to the skin, where they can infect the next black fly that bites the person. There are a number of ways to make the diagnosis, including: placing a biopsy of the skin in normal saline and watching for the larva to come out; looking in the eye for larvae; and looking within the bumps under the skin for adult worms. A vaccine against the disease does not exist. Prevention is by avoiding being bitten by flies. This may include the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Strongyloidiasis
Strongyloidiasis is a human parasitic disease caused by the nematode called ''Strongyloides stercoralis'', or sometimes the closely related ''S. fülleborni''. These helminths belong to a group of nematodes called roundworms. These intestinal worms can cause a number of symptoms in people, principally skin symptoms, abdominal pain, diarrhea and weight loss, but also many other specific and vague symptoms in disseminated disease, and severe life-threatening conditions through hyperinfection. In some people, particularly those who require corticosteroids or other immunosuppressive medication, ''Strongyloides'' can cause a hyperinfection syndrome that can lead to death if untreated. The diagnosis is made by blood and stool tests. The medication ivermectin is widely used to treat strongyloidiasis. Strongyloidiasis is a type of soil-transmitted helminthiasis. Low estimates postulate it to affect 30–100 million people worldwide, mainly in tropical and subtropical countries, while ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ivermectin
Ivermectin (, '' EYE-vər-MEK-tin'') is an antiparasitic drug. After its discovery in 1975, its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. Approved for human use in 1987, today it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis. It works through many mechanisms to kill the targeted parasites, and can be taken orally, or applied to the skin for external infestations. It belongs to the avermectin family of medications. William Campbell and Satoshi Ōmura won the 2015 Nobel Prize in Physiology or Medicine for its discovery and applications. It is on the World Health Organization's List of Essential Medicines, and is approved by the U.S. Food and Drug Administration as an antiparasitic agent. In 2018, it was the 420th most commonly prescribed medication in the United States, with more than 100,000 prescriptions. It is availab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Salmon Louse
The salmon louse (''Lepeophtheirus salmonis'') is a species of copepod in the genus ''Lepeophtheirus''. It is a sea louse, a parasite living mostly on Salmonidae, salmon, particularly on Pacific and Atlantic salmon and sea trout, but is also sometimes found on the three-spined stickleback. It feeds on the mucus, skin and blood of the fish."Sea Lice." Marine Institute. Marine Institute, n. d. Web. 10 Dec. 2013. . Once detached, they can be blown by wind across the surface of the sea, like plankton. When they encounter a suitable marine fish host, they adhere themselves to the skin, fins, or gills of the fish, and feed on the mucus or skin. Sea lice only affect fish and are not harmful to humans. Salmon lice are ectoparasites of salmon. In the 1980s, high levels of salmon lice were observed on pink salmon smolts. Salmon lice are found in the Pacific and Atlantic Oceans; they infect pink salmon, Atlantic salmon, and chum salmon. Life cycle Some research has occurred on the proble ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methanol
Methanol (also called methyl alcohol and wood spirit, amongst other names) is an organic chemical and the simplest aliphatic alcohol, with the formula C H3 O H (a methyl group linked to a hydroxyl group, often abbreviated as MeOH). It is a light, volatile, colourless, flammable liquid with a distinctive alcoholic odour similar to that of ethanol (potable alcohol). A polar solvent, methanol acquired the name wood alcohol because it was once produced chiefly by the destructive distillation of wood. Today, methanol is mainly produced industrially by hydrogenation of carbon monoxide. Methanol consists of a methyl group linked to a polar hydroxyl group. With more than 20 million tons produced annually, it is used as a precursor to other commodity chemicals, including formaldehyde, acetic acid, methyl tert-butyl ether, methyl benzoate, anisole, peroxyacids, as well as a host of more specialised chemicals. Occurrence Small amounts of methanol are present in normal, healthy hu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acetone
Acetone (2-propanone or dimethyl ketone), is an organic compound with the formula . It is the simplest and smallest ketone (). It is a colorless, highly volatile and flammable liquid with a characteristic pungent odour. Acetone is miscible with water and serves as an important organic solvent in its own right, in industry, home, and laboratory. About 6.7 million tonnes were produced worldwide in 2010, mainly for use as a solvent and production of methyl methacrylate (and from that PMMA) as well as bisphenol A.Acetone World Petrochemicals report, January 2010Stylianos Sifniades, Alan B. Levy, "Acetone" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2005. It is a common building block in |
Polysorbate
Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. They are commonly used in oral and topical pharmaceutical dosage forms. They are also often used in cosmetics to solubilize essential oils into water-based products. Polysorbates are oily liquids derived from ethoxylated sorbitan (a derivative of sorbitol) esterified with fatty acids. Common brand names for polysorbates include Kolliphor, Scattics, Alkest, Canarcel, and Tween.Hubert Schiweck, Albert Bär, Roland Vogel, Eugen Schwarz, Markwart Kunz, Cécile Dusautois, Alexandre Clement, Caterine Lefranc, Bernd Lüssem, Matthias Moser, Siegfried Peters "Sugar Alcohols" Ullmann's Encyclopedia of Industrial Chemistry, 2012, Wiley-VCH, Weinheim. Examples * Polysorbate 20 (polyoxyethylene (20) sorbitan monolaurate) * Polysorbate 40 (polyoxyethylene (20) sorbitan monopalmitate) * Polysorbate 60 (polyoxyethylene (20) sorbitan monostearate) * Polysorbate 80 (polyoxyethylene (20) sorbitan monool ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
