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Duct Tape Occlusion Therapy
Duct tape occlusion therapy (DTOT) is a method of treating warts by covering them with duct tape for prolonged periods. The manner in which duct tape appears to work is unclear. The tape might create a macerating and keratolytic environment, stimulating an immune response. The type of adhesive in the duct tape is likely to be important as leeching of the adhesive into the skin may be causing the immune system response. Side effects can include skin irritation and peeling. There is mixed evidence that occlusive treatment with various types of duct tape is effective. Clinical trials in 2012 concluded that no statistically significant difference between clear duct tape and placebo could be determined within the sample. On health information websites, duct tape is referred to as a treatment with mixed evidence of efficacy, no good evidence or described as alternative medicine. Despite the mixed evidence for efficacy, the simplicity of the method and its limited side-effects leads som ...
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Wart
Warts are typically small, rough, hard growths that are similar in color to the rest of the skin. They typically do not result in other symptoms, except when on the bottom of the feet, where they may be painful. While they usually occur on the hands and feet, they can also affect other locations. One or many warts may appear. They are not cancerous. Warts are caused by infection with a type of human papillomavirus (HPV). Factors that increase the risk include use of public showers and pools, working with meat, eczema and a weak immune system. The virus is believed to enter the body through skin that has been damaged slightly. A number of types exist, including "common warts", plantar warts, " filiform warts", and genital warts. Genital warts are often sexually transmitted. Without treatment, most types of warts resolve in months to years. A number of treatments may speed resolution, including salicylic acid applied to the skin and cryotherapy. In those who are otherwise he ...
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Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few varia ...
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Statistical Power
In statistics, the power of a binary hypothesis test is the probability that the test correctly rejects the null hypothesis (H_0) when a specific alternative hypothesis (H_1) is true. It is commonly denoted by 1-\beta, and represents the chances of a true positive detection conditional on the actual existence of an effect to detect. Statistical power ranges from 0 to 1, and as the power of a test increases, the probability \beta of making a type II error by wrongly failing to reject the null hypothesis decreases. Notation This article uses the following notation: * ''β'' = probability of a Type II error, known as a "false negative" * 1 − ''β'' = probability of a "true positive", i.e., correctly rejecting the null hypothesis. "1 − ''β''" is also known as the power of the test. * ''α'' = probability of a Type I error, known as a "false positive" * 1 − ''α'' = probability of a "true negative", i.e., correctly not rejecting the null hypothesis Description For a ty ...
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Moleskin
Moleskin is a heavy cotton fabric, woven and then shorn to create a short, soft pile on one side. The feel and appearance of its nap is suede-like, less plush than velour and more like felt or chamois. The word is also used for clothing made from this fabric. Clothing made from moleskin is noted for its softness and durability. Some variants of the cloth are so densely woven as to be windproof. Its name is due to the soft brushed hand of the fabric, similar to mole fur. Though mole pelts have been used to make fur clothing, they are not referred to as "moleskin", which is also a term for soft, dense adhesive pads stuck to the skin to prevent blisters. Structure Moleskin is woven of carded cotton yarn in a dense weft-faced satin weave. The surface is napped or shorn to "produce a suede-like finish". Uses Moleskin fabric is commonly used to make trousers, also referred to as "moleskins", that are similar to jeans in terms of cut and construction. They similarly started as w ...
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Placebo Group
Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary ...
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Pumice Stone
Pumice (), called pumicite in its powdered or dust form, is a volcanic rock that consists of highly vesicular rough-textured volcanic glass, which may or may not contain crystals. It is typically light-colored. Scoria is another vesicular volcanic rock that differs from pumice in having larger vesicles, thicker vesicle walls, and being dark colored and denser.Jackson, J.A., J. Mehl, and K. Neuendorf (2005) ''Glossary of Geology'' American Geological Institute, Alexandria, Virginia. 800 pp. McPhie, J., M. Doyle, and R. Allen (1993) ''Volcanic Textures A guide to the interpretation of textures in volcanic rocks'' Centre for Ore Deposit and Exploration Studies, University of Tasmania, Hobart, Tasmania..198 pp. Pumice is created when super-heated, highly pressurized rock is violently ejected from a volcano. The unusual foamy configuration of pumice happens because of simultaneous rapid cooling and rapid depressurization. The depressurization creates bubbles by lowering the solubi ...
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Emery Board
A nail file is a tool used to gently grind down and shape the edges of nails. They are often used in manicures and pedicures after the nail has been trimmed using appropriate nail clippers. Nail files may either be emery boards, ceramic, glass, crystal, plain metal files or metal files coated with corundum. A nail drill is a powered rotary tool, which is used by a nail technician to file nails. Materials Emery board Emery boards are small flat long objects which have emery or emery paper glued to them, making them both abrasive and flexible, used for fingernail and toenail care. They are used by manicurists to shape and smooth the nail during manicure and pedicure sessions. Emery boards are inexpensive and disposable, making them a sanitary alternative to metal nail files. The emery board was first patented by J. Parker Pray of New York in 1883. Emery boards are generally less abrasive than metal nail files, and hence, emery boards may take longer to file down nails than ...
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Debridement
Debridement is the medical removal of dead, damaged, or infected tissue to improve the healing potential of the remaining healthy tissue. Removal may be surgical, mechanical, chemical, autolytic (self-digestion), and by maggot therapy. In podiatry, practitioners such as chiropodists, podiatrists and foot health practitioners remove conditions such as calluses and verrucas. Debridement is an important part of the healing process for burns and other serious wounds; it is also used for treating some kinds of snake and spider bites. Sometimes the boundaries of the problem tissue may not be clearly defined. For example, when excising a tumor, there may be micrometastases along the edges of the tumor that are too small to be detected, but if not removed, could cause a relapse. In such circumstances, a surgeon may opt to debride a portion of the surrounding healthy tissue to ensure that the tumor is completely removed. Types There is lack of high quality evidence to compare th ...
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Toxin
A toxin is a naturally occurring organic poison produced by metabolic activities of living cells or organisms. Toxins occur especially as a protein or conjugated protein. The term toxin was first used by organic chemist Ludwig Brieger (1849–1919) and is derived from the word toxic. Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors. Toxins vary greatly in their toxicity, ranging from usually minor (such as a bee sting) to potentially fatal even at extremely low doses (such as botulinum toxin). Toxins are largely secondary metabolites, which are organic compounds that are not directly involved in an organism's growth, development, or reproduction, instead often aiding it in matters of defense. Terminology Toxins are often distinguished from other chemical agents strictly based on their biological origin. Le ...
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Duct Tape
Duct tape (also called duck tape, from the cotton duck cloth it was originally made of) is cloth- or scrim-backed pressure-sensitive tape, often coated with polyethylene. There are a variety of constructions using different backings and adhesives, and the term 'duct tape' has been genericized to refer to different cloth tapes with differing purposes. A variation is heat-resistant foil tape useful for sealing heating and cooling ducts, produced because the adhesive on standard duct tape fails and the synthetic fabric reinforcement mesh deteriorates when used on heating ducts. Duct tape is generally silvery gray in color, but also available in other colors and printed designs, from whimsical yellow ducks, college logos to practical camouflage patterns. It is often confused with gaffer tape (which is designed to be non-reflective and cleanly removed, unlike duct tape). During World War II, Revolite (then a division of Johnson & Johnson) developed an adhesive tape made from ...
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Alternative Medicine
Alternative medicine is any practice that aims to achieve the healing effects of medicine despite lacking biological plausibility, testability, repeatability, or evidence from clinical trials. Complementary medicine (CM), complementary and alternative medicine (CAM), integrated medicine or integrative medicine (IM), and holistic medicine attempt to combine alternative practices with those of mainstream medicine. Alternative therapies share in common that they reside outside of medical science and instead rely on pseudoscience. Traditional practices become "alternative" when used outside their original settings and without proper scientific explanation and evidence. Frequently used derogatory terms for relevant practices are ''new age'' or ''pseudo-'' medicine, with little distinction from quackery. Some alternative practices are based on theories that contradict the established science of how the human body works; others resort to the supernatural or superstitious to explain ...
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Placebo
A placebo ( ) is a substance or treatment which is designed to have no therapeutic value. Common placebos include inert tablets (like sugar pills), inert injections (like Saline (medicine), saline), sham surgery, and other procedures. In general, placebos can affect how patients perceive their condition and encourage the body's chemical processes for relieving pain and a few other symptoms, but have no impact on the disease itself. Improvements that patients experience after being treated with a placebo can also be due to unrelated factors, such as regression to the mean (a statistical effect where an unusually high or low measurement is likely to be followed by a less extreme one). The use of placebos in clinical medicine raises ethical concerns, especially if they are disguised as an active treatment, as this introduces dishonesty into the doctor–patient relationship and bypasses informed consent. While it was once assumed that this deception was necessary for placebos to have ...
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