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Drug Science
DrugScience or ''Drug Science'' (originally called the Independent Scientific Committee on Drugs (ISCD)) is a UK-based drugs advisory committee proposed and initially funded by hedge fund manager Toby Jackson. It is chaired by Professor David Nutt and was officially launched on 15 January 2010 with the help of the Centre for Crime and Justice Studies. The primary aim of the committee is to review and investigate the scientific evidence of drug harms without the political interference that could result from government affiliation.Sacked scientist promises impartial drugs advice
''The '', January 2010
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Governmental Organization
A government or state agency, sometimes an appointed commission, is a permanent or semi-permanent organization in the machinery of government that is responsible for the oversight and administration of specific functions, such as an administration. There is a notable variety of agency types. Although usage differs, a government agency is normally distinct both from a department or ministry, and other types of public body established by government. The functions of an agency are normally executive in character since different types of organizations (''such as commissions'') are most often constituted in an advisory role—this distinction is often blurred in practice however, it is not allowed. A government agency may be established by either a national government or a state government within a federal system. Agencies can be established by legislation or by executive powers. The autonomy, independence, and accountability of government agencies also vary widely. History Early exa ...
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SAGE Publishing
SAGE Publishing, formerly SAGE Publications, is an American independent publishing company founded in 1965 in New York by Sara Miller McCune and now based in Newbury Park, California. It publishes more than 1,000 journals, more than 800 books a year, reference works and electronic products covering business, humanities, social sciences, science, technology and medicine. SAGE also owns and publishes under the imprints of Corwin Press (since 1990), CQ Press (since 2008), Learning Matters (since 2011), and Adam Matthew Digital (since 2012). History SAGE was founded in 1965 in New York City by Sara Miller (later Sara Miller McCune) with Macmillan Publishers executive George D. McCune as a mentor; the name of the company is an acronym formed from the first letters of their given names. SAGE relocated to Southern California in 1966, after Miller and McCune married; McCune left Macmillan to formally join the company at that time. Sara Miller McCune remained president for 18 years ...
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Channel 4
Channel 4 is a British free-to-air public broadcast television network operated by the state-owned enterprise, state-owned Channel Four Television Corporation. It began its transmission on 2 November 1982 and was established to provide a fourth television service in the United Kingdom. At the time, the only other channels were the television licence, licence-funded BBC One and BBC Two, and a single commercial broadcasting network ITV (TV network), ITV. The network's headquarters are based in London and Leeds, with creative hubs in Glasgow and Bristol. It is publicly owned and advertising-funded; originally a subsidiary of the Independent Broadcasting Authority (IBA), the station is now owned and operated by Channel Four Television Corporation, a public corporation of the Department for Digital, Culture, Media and Sport, which was established in 1990 and came into operation in 1993. Until 2010, Channel 4 did not broadcast in Wales, but many of its programmes were re-broadcast ...
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FMRI
Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area of the brain is in use, blood flow to that region also increases. The primary form of fMRI uses the blood-oxygen-level dependent (BOLD) contrast, discovered by Seiji Ogawa in 1990. This is a type of specialized brain and body scan used to map neural activity in the brain or spinal cord of humans or other animals by imaging the change in blood flow (hemodynamic response) related to energy use by brain cells. Since the early 1990s, fMRI has come to dominate brain mapping research because it does not involve the use of injections, surgery, the ingestion of substances, or exposure to ionizing radiation. This measure is frequently corrupted by noise from various sources; hence, statistical procedures are used to extract the underlying signal. T ...
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Drugs Live
''Drugs Live'' is an occasional British television documentary on Channel 4 about recreational drug use, and clinical trials into its effects, presented by Jon Snow and Dr Christian Jessen. Format The show consisted of a one-hour debate, interspersed with explanations of brain-chemistry using a giant luminous brain, footage of a veteran raver taking ecstasy and dancing until 5 am, and interviews with three students. Ecstasy trial The first programme ''Drugs Live: The Ecstasy Trial'' was broadcast in two parts on 26 & 27 September 2012, about MDMA. The main guests were Professor Valerie Curran and Professor David Nutt. Curran and Nutt oversaw research at Imperial College London in which volunteers took part in a double blind study in which some took 83 mg of MDMA, some took Vitamin C, and others a placebo. Participants had their brains scanned using a functional magnetic resonance imaging brain scanner whilst scientists asked them questions about their mood and memory. Fiv ...
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National Health Service
The National Health Service (NHS) is the umbrella term for the publicly funded healthcare systems of the United Kingdom (UK). Since 1948, they have been funded out of general taxation. There are three systems which are referred to using the "NHS" name ( NHS England, NHS Scotland and NHS Wales). Health and Social Care in Northern Ireland was created separately and is often locally referred to as "the NHS". The four systems were established in 1948 as part of major social reforms following the Second World War. The founding principles were that services should be comprehensive, universal and free at the point of delivery—a health service based on clinical need, not ability to pay. Each service provides a comprehensive range of health services, free at the point of use for people ordinarily resident in the United Kingdom apart from dental treatment and optical care. In England, NHS patients have to pay prescription charges; some, such as those aged over 60 and certain state ben ...
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Public Health England
Public Health England (PHE) was an executive agency of the Department of Health and Social Care in England which began operating on 1 April 2013 to protect and improve health and wellbeing and reduce health inequalities. Its formation came as a result of the reorganisation of the National Health Service (NHS) in England outlined in the Health and Social Care Act 2012. It took on the role of the Health Protection Agency, the National Treatment Agency for Substance Misuse and a number of other health bodies. It was an executive agency of the Department of Health and Social Care, and a distinct delivery organisation with operational autonomy. On 29 March 2021, the UK Government announced that PHE would be disbanded and that its public health functions would be transferred, in proposals to reform public health structures. From 1 October 2021, PHE's health protection functions were formally transferred into the UK Health Security Agency (UKHSA), while its health improvement functions ...
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Electronic Cigarette
An electronic cigarette is an electronic device that simulates tobacco smoking. It consists of an atomizer, a power source such as a battery, and a container such as a cartridge or tank. Instead of smoke, the user inhales vapor. As such, using an e-cigarette is often called "vaping". The atomizer is a heating element that vaporizes a liquid solution called e-liquid, which quickly cools into an aerosol of tiny droplets, vapor and air. E-cigarettes are activated by taking a puff or pressing a button. Some look like traditional cigarettes, and most kinds are reusable. The vapor mainly comprises propylene glycol and/or glycerin, usually with nicotine and flavoring. Its exact composition varies, and depends on several things including user behavior. Vaping is likely much less harmful than smoking. E-cigarette vapor contains fewer toxins than cigarette smoke. It contains traces of harmful substances not found in cigarette smoke. Nicotine is highly addictive. Users beco ...
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Nicotine Patch
A nicotine patch is a transdermal patch that releases nicotine into the body through the skin. It is used in nicotine replacement therapy (NRT), a process for smoking cessation. Endorsed and approved by the U.S. Food and Drug Administration (FDA), it is considered one of the safer NRTs available for the treatment of tobacco use disorder. Nicotine replacement products including gum and transdermal patches are on the World Health Organization's List of Essential Medicines. Medical uses Effectiveness A meta-analysis found that fewer than 20% of people treated with nicotine replacement therapy remain abstinent from smoking at one year. History The first study of the pharmacokinetics of a transdermal nicotine patch in humans was published in 1984 by Jed Rose, Murray Jarvik, and Daniel Rose, and was followed by publication by Rose et al. (1985) of results of a study of smokers showing that a transdermal nicotine patch reduced craving for cigarettes. Frank Etscorn filed a patent ...
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Psilocybin Mushroom
Psilocybin mushrooms, commonly known as magic mushrooms, are a polyphyletic informal group of mushroom, fungi that contain psilocybin which turns into psilocin upon ingestion. Biological genera containing psilocybin mushrooms include ''Psilocybe'', ''Panaeolus'' (including ''Copelandia''), ''Inocybe'', ''Pluteus'', ''Gymnopilus'', and ''Pholiotina''. Psilocybin mushrooms have been and continue to be used in indigenous New World cultures in religious, Divination, divinatory, or Spirituality, spiritual contexts. Psilocybin mushrooms are also used as recreational drugs. They may be depicted in Stone Age rock art in Africa and Europe, but are most famously represented in the Pre-Columbian sculptures and glyphs seen throughout North, Central and South America. History Early Prehistoric rock arts near Villar del Humo in Spain, suggests that ''Psilocybe hispanica'' was used in religious rituals 6,000 years ago. The hallucinogenic species of the Psilocybe genus have a history of us ...
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