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Dimethylphenethylamine
Dimethylphenethylamine may refer to: * α,α-Dimethylphenethylamine Phentermine ( phenyl- tertiary-butyl amine), with several brand names including Ionamin and Sentis, is a medication used together with diet and exercise to treat obesity. It is taken by mouth for up to a few weeks at a time, after which the ben ... (phentermine) * ''N'',α-Dimethylphenethylamine (methamphetamine) * ''N'',β-Dimethylphenethylamine (phenpromethamine) * 2,α-Dimethylphenethylamine (ortetamine) * 3,α-Dimethylphenethylamine (3-methylamphetamine) * 4,α-Dimethylphenethylamine (4-methylamphetamine) * ''N'',''N''-Dimethylphenethylamine * α,β-Dimethylphenethylamine (2-phenyl-3-aminobutane) {{chemistry index ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N,α-Dimethylphenethylamine
Methamphetamine (contracted from ) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. Methamphetamine was discovered in 1893 and exists as two enantiomers: levo-methamphetamine and dextro-methamphetamine. ''Methamphetamine'' properly refers to a specific chemical substance, the racemic free base, which is an equal mixture of levomethamphetamine and dextromethamphetamine in their pure amine forms. It is rarely prescribed over concerns involving human neurotoxicity and potential for recreational use as an aphrodisiac and euphoriant, among other concerns, as well as the availability of safer substitute drugs with comparable treatment efficacy such as Adderall and Vyvanse. Dextromethamphetamine is a stronger CNS stimulant than levomethamphetamine. Both racemic methamphetamine and dextromethamphetamine are illicitly trafficked and sold ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
α,α-Dimethylphenethylamine
Phentermine ( phenyl- tertiary-butyl amine), with several brand names including Ionamin and Sentis, is a medication used together with diet and exercise to treat obesity. It is taken by mouth for up to a few weeks at a time, after which the benefits subside. It is also available as the combination phentermine/topiramate. Common side effects include a fast heart beat, high blood pressure, trouble sleeping, dizziness, and restlessness. Serious side effects may include abuse but do not include pulmonary hypertension, valvular heart disease as the latter were caused by the fenfluramine component of the fen-phen drug combination. Use is not recommended during pregnancy or breastfeeding, or with SSRIs or MAO inhibitors. It works mainly as an appetite suppressant, likely as a result of being a CNS stimulant. Chemically, phentermine is a substituted amphetamine. Phentermine was approved for medical use in the United States in 1959. It is available as a generic medication. In 2020, i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N,β-Dimethylphenethylamine
Phenpromethamine (former brand name Vonedrine), also known as ''N'',β-dimethylphenethylamine, is a sympathomimetic nasal decongestant of the phenethylamine group. It was previously marketed as a nasal inhaler from 1943 through 1960 but is no longer available. The medication is a stimulant and is banned by the World Anti-Doping Agency. It has been detected in dietary supplements starting in the 2010s. See also * β-Methylphenethylamine * Methamphetamine * N-Methylphenethylamine ''N''-Methylphenethylamine (NMPEA) is a naturally occurring trace amine neuromodulator in humans that is derived from the trace amine, phenethylamine (PEA). It has been detected in human urine (<1 μg over 24 hours) and is produced b ... References Abandoned drugs[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N,N-Dimethylphenethylamine
''N'',''N''-Dimethylphenethylamine (''N'',''N''-DMPEA) is a substituted phenethylamine that is used as a flavoring agent. It is an alkaloid that was first isolated from the orchid '' Eria jarensis''. Its aroma is described as "sweet, fishy". It is mainly used in cereal, cheese, dairy products, fish, fruit and meat. It is also being used in pre-workout and bodybuilding supplements with claims of a stimulant effect. There is also evidence suggesting that ''N'',''N''-DMPEA acts as a TAAR1 agonist in humans, and as a 5-HT1A ligand in rats. Some less conclusive research also indicated that it had interaction with MAO-B, most likely as an enzyme substrate and not an inhibitor. ''N'',''N''-DMPEA is a positional isomer of methamphetamine. Safety N,N-DMPEA has been found to be safe for use as a flavoring agent by the Flavor and Extract Manufacturers Association (FEMA) Expert Panel and also by the Joint Expert Committee on Food Additives (JECFA)—a collaboration between the Food and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2,α-Dimethylphenethylamine
Ortetamine (INN), also known as 2-methylamphetamine, is a stimulant drug of the amphetamine class. In animal drug discrimination tests it substituted for dextroamphetamine more closely than either 3- or 4-methylamphetamine, although with only around 1/10 the potency of dextroamphetamine itself. Legal status Sweden's public health agency classified 2-MA as a narcotic substance, on January 18, 2019. Ortetamine is an isomer of Methamphetamine, therefore, a Schedule II Controlled Substance in the United States. See also * 2-Fluoroamphetamine * 2-Methylmethcathinone * 2-Me-PVP * 3-Methylamphetamine * 4-Methylamphetamine 4-Methylamphetamine (4-MA; PAL-313; Aptrol; p-TAP) is a stimulant and anorectic drug of the phenethylamine and amphetamine chemical classes. In vitro, it acts as a potent and balanced serotonin, norepinephrine, and dopamine releasing agent with ... * 2-Methoxymethamphetamine References Designer drugs Substituted amphetamines Norepinephrine-dopami ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3-Methylamphetamine
3-Methylamphetamine (3-MeA; PAL-314) is a stimulant drug from the amphetamine family. It is self-administered by mice to a similar extent to 4-fluoroamphetamine and has comparable properties as a monoamine releaser, although with a more balanced release of all three monoamines, as opposed to the more dopamine/noradrenaline selective fluoro analogues. See also * 2-Methylamphetamine * 3-Methylmethamphetamine * 4-Methylamphetamine 4-Methylamphetamine (4-MA; PAL-313; Aptrol; p-TAP) is a stimulant and anorectic drug of the phenethylamine and amphetamine chemical classes. In vitro, it acts as a potent and balanced serotonin, norepinephrine, and dopamine releasing agent with ... * 3,4-Dimethylamphetamine * 3-Trifluoromethylamphetamine References Substituted amphetamines Serotonin-norepinephrine-dopamine releasing agents {{nervous-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
4-Methylamphetamine
4-Methylamphetamine (4-MA; PAL-313; Aptrol; p-TAP) is a stimulant and anorectic drug of the phenethylamine and amphetamine chemical classes. In vitro, it acts as a potent and balanced serotonin, norepinephrine, and dopamine releasing agent with Ki affinity values of 53.4nM, 22.2nM, and 44.1nM at the serotonin, norepinephrine, and dopamine transporters, respectively. However, more recent ''in vivo'' studies that involved performing microdialysis on rats showed a different trend. These studies showed that 4-methylamphetamine is much more potent at elevating serotonin (~18 x baseline) relative to dopamine (~5 x baseline). The authors speculated that this is because 5-HT release dampens DA release through some mechanism. For example, it was suggested that a possible cause for this could be activation of 5HT2C receptors since this is known to inhibit DA release. In addition there are alternative explanations such as 5-HT release then going on to encourage GABA release, which has an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
