Corosolic Acid
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Corosolic Acid
Corosolic acid is a pentacyclic triterpene acid found in '' Lagerstroemia speciosa''. It is similar in structure to ursolic acid, differing only in the fact that it has a 2-alpha-hydroxy attachment. References Triterpenes Organic acids {{organic-compound-stub ...
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Triterpene
Triterpenes are a class of chemical compounds composed of three terpene units with the molecular formula C30H48; they may also be thought of as consisting of six isoprene units. Animals, plants and fungi all produce triterpenes, including squalene, the precursor to all steroids. Structures Triterpenes exist in a great variety of structures. Nearly 200 different skeletons have been identified. These skeletons may be broadly divided according to the number of rings present. In general pentacyclic structures (5 rings) tend to dominate. Squalene is biosynthesized through the head-to-head condensation of two farnesyl pyrophosphate units. This coupling converts a pair of C15 components into a C30 product. Squalene serves as precursor for the formation of many triterpenoids, including bacterial hopanoids and eukaryotic sterols. Triterpenoids By definition triterpenoids are triterpenes that possess heteroatoms, usually oxygen. The terms ''triterpene'' and ''triterpenoid'' oft ...
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Lagerstroemia Speciosa
''Lagerstroemia speciosa'' (giant crepe-myrtle, Queen's crepe-myrtle, banabá plant, or pride of India) is a species of ''Lagerstroemia'' native to tropical southern Asia. It is a deciduous tree with bright pink to light purple flowers. Etymology The genus ''Lagerstroemia'' was first described by Carl Linnaeus. The name ''Lagerstroemia'' recognizes Magnus von Lagerstroem, a Swedish naturalist who provided specimens from the East for Linnaeus. Names * English : Pride of India, Queen Crepe Myrtle * bn, জারুল () * hi, जरुल () * id, Bungur * pam, Banába * mr, ताम्हण (), (), () * as, এজাৰ () * tl, Banaba * vi, Bằng lăng nước * mal, മണിമരുത്,പൂമരുത് * th, อินทนิล () * Tamil :கதலி (மலர்) * ms, Bungor raya Growth It is a small to medium-sized tree growing to tall, with smooth, flaky bark. The leaves are deciduous, oval to elliptic, long and broad, with an acute ap ...
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Ursolic Acid
Ursolic acid (sometimes referred to as urson, prunol, malol, or 3β-hydroxyurs-12-en-28-oic acid), is a pentacyclic triterpenoid identified in the epicuticular waxes of apples as early as 1920 and widely found in the peels of fruits, as well as in herbs and spices like rosemary and thyme. Natural occurrence Ursolic acid is present in many plants, such as ''Mirabilis jalapa'', as well as in many fruits and herbs used in daily life (e.g. apples, basil and holy basil, bilberries, cranberries, elder flower, peppermint, rosemary, lavender, oregano, thyme, hawthorn, and prunes). Apple peels contain large quantities of ursolic acid and related compounds. Potential biochemical effects A number of potential biochemical effects of ursolic acid have been investigated, but there has been no clinical study demonstrating benefits to human health. ''In vitro'', ursolic acid inhibits the proliferation of various cancer cell types by inhibiting the STAT3 activation pathway, and may also d ...
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Ursolic Acid
Ursolic acid (sometimes referred to as urson, prunol, malol, or 3β-hydroxyurs-12-en-28-oic acid), is a pentacyclic triterpenoid identified in the epicuticular waxes of apples as early as 1920 and widely found in the peels of fruits, as well as in herbs and spices like rosemary and thyme. Natural occurrence Ursolic acid is present in many plants, such as ''Mirabilis jalapa'', as well as in many fruits and herbs used in daily life (e.g. apples, basil and holy basil, bilberries, cranberries, elder flower, peppermint, rosemary, lavender, oregano, thyme, hawthorn, and prunes). Apple peels contain large quantities of ursolic acid and related compounds. Potential biochemical effects A number of potential biochemical effects of ursolic acid have been investigated, but there has been no clinical study demonstrating benefits to human health. ''In vitro'', ursolic acid inhibits the proliferation of various cancer cell types by inhibiting the STAT3 activation pathway, and may also d ...
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Triterpenes
Triterpenes are a class of chemical compounds composed of three terpene units with the molecular formula C30H48; they may also be thought of as consisting of six isoprene units. Animals, plants and fungi all produce triterpenes, including squalene, the precursor to all steroids. Structures Triterpenes exist in a great variety of structures. Nearly 200 different skeletons have been identified. These skeletons may be broadly divided according to the number of rings present. In general pentacyclic structures (5 rings) tend to dominate. Squalene is biosynthesized through the head-to-head condensation of two farnesyl pyrophosphate units. This coupling converts a pair of C15 components into a C30 product. Squalene serves as precursor for the formation of many triterpenoids, including bacterial hopanoids and eukaryotic sterols. Triterpenoids By definition triterpenoids are triterpenes that possess heteroatoms, usually oxygen. The terms ''triterpene'' and ''triterpenoid'' oft ...
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