|
Conidiobolomycosis
Conidiobolomycosis is a rare long-term fungal infection that is typically found just under the skin of the nose, sinuses, cheeks and upper lips. It may present with a nose bleed or a blocked or runny nose. Typically there is a firm painless swelling which can slowly extend to the nasal bridge and eyes, sometimes causing facial disfigurement. Most cases are caused by ''Conidiobolus coronatus'', a fungus found in soil and in the environment in general, which can infect healthy people. It is usually acquired by inhaling the spores of the fungus, but can be by direct infection through a cut in the skin such as an insect bite. The extent of disease may be seen using medical imaging such as CT scanning of the nose and sinus. Diagnosis may be confirmed by biopsy, microscopy, culture and histopathology. Treatment is with long courses of antifungals and sometimes cutting out infected tissue. The condition has a good response to antifungal treatment, but can recur. The infecti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basidiobolomycosis
Basidiobolomycosis is a mycosis, fungal disease caused by ''Basidiobolus ranarum''. It may appear as one or more painless firm nodule (medicine), nodules in the skin which becomes purplish with an edge that appears to be slowly growing outwards. A serious but less common type affects the gastrointestinal tract, stomach and intestine, which usually presents with tummy ache, fever and a Abdominal mass, lump. ''B. ranarum'', can be found in soil, decaying vegetables and has been isolated from insects, some reptiles, amphibians, and mammals. The disease results from direct entry of the fungus through broken skin such as an Insect bites and stings, insect bite or trauma, or eating contaminated food. It generally affects people who are well. Diagnosis is by medical imaging, biopsy, microscopy, culture and histopathology. Treatment usually involves amphotericin B and surgery. Although ''B. ranarum'' is found around the world, the disease Basidiobolomycosis is generally reported in Tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Entomophthoromycosis
Entomophthoramycosis (or Entomophthoromycosis) is a mycosis caused by Entomophthorales. Examples include basidiobolomycosis and conidiobolomycosis. Signs and symptoms Diagnosis A culture of the infected tissue of the individual suspected of having Entomophthoramycosis Treatment Treatment for phycomycosis is very difficult and includes surgery when possible. Postoperative recurrence is common. Antifungal drugs show only limited effect on the disease, but itraconazole and terbinafine hydrochloride are often used for two to three months following surgery. Humans with ''Basidiobolus'' infections have been treated with amphotericin B and potassium iodide. For pythiosis and lagenidiosis, a new drug targeting water moulds called caspofungin is available, but it is very expensive. Immunotherapy Immunotherapy or biological therapy is the treatment of disease by activating or suppressing the immune system. Immunotherapies designed to elicit or amplify an immune response are classif ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Conidiobolus
''Conidiobolus'' is a genus of fungi in order Entomophthorales. Some species were defined in ''Conidiobolus'' but then moved into other genera such as ''Capillidium'' and ''Batkoa''. This genus can cause a human infection known as conidiobolomycosis. Species There are 54 species of ''Conidiobolus''. *''Conidiobolus adieretus'' Drechsler, 1953 (= '' Capillidium adiaeretum'' (Drechsler) B. Huang & Y. Nie (2020)) *'' Conidiobolus antarcticus'' S. Tosi, Caretta & Humber, 2004 *'' Conidiobolus apiculatus'' *'' Conidiobolus bangalorensis'' Sriniv. & Thirum., 1967 *'' Conidiobolus batkoi'' *'' Conidiobolus brefeldianus'' Couch, 1939 *'' Conidiobolus caecilius'' S. Keller, 2007 *'' Conidiobolus carpentieri'' (Giard) Remaud. & S. Keller, 1980 *'' Conidiobolus cercopidis'' *'' Conidiobolus cercopidis'' *'' Conidiobolus chlamydosporus'' Drechsler, 1955 *'' Conidiobolus chlapowskii'' Bałazy, J. Wiśn. & S. Kaczm., 1987 *'' Conidiobolus conglomeratus'' *''Conidiobolus coronatus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Itraconazole
Itraconazole, sometimes abbreviated ITZ, is an antifungal medication used to treat a number of fungal infections. This includes aspergillosis, blastomycosis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis. It may be given by mouth or intravenously. Common side effects include nausea, diarrhea, abdominal pain, rash, and headache. Severe side effects may include liver problems, heart failure, Stevens–Johnson syndrome and allergic reactions including anaphylaxis. It is unclear if use during pregnancy or breastfeeding is safe. It is in the triazole family of medications. It stops fungal growth by affecting the cell membrane or affecting their metabolism. Itraconazole was patented in 1978 and approved for medical use in the United States in 1992. It is on the World Health Organization's List of Essential Medicines. Recent research works suggest itraconazole (ITZ) could also be used in the treatment of cancer by inhibiting the hedgehog pathway in a similar way to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sinusitis
Sinusitis, also known as rhinosinusitis, is inflammation of the nasal mucosa, mucous membranes that line the paranasal sinuses, sinuses resulting in symptoms that may include thick Mucus#Respiratory system, nasal mucus, a nasal congestion, plugged nose, and Orofacial pain, facial pain. Other signs and symptoms may include fever, headaches, a hyposmia, poor sense of smell, sore throat, a feeling that phlegm is oozing out from the back of the nose to the throat along with a necessity to clear the throat frequently and frequent attacks of cough. Generally sinusitis starts off as a common viral infection like common cold. This infection generally subsides within 5 to 7 days. During this time the nasal structures can swell and facilitate the stagnation of fluids in sinuses that leads to acute (medicine), acute sinusitis which lasts from 6th day of the infection to 15th day. From the 15th day to 45th day of the infection comes the subacute stage followed by chronic (medicine), chronic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
