Colorectal Metaplasia
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Colorectal Metaplasia
The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the digestive system in tetrapods. Water is absorbed here and the remaining waste material is stored in the rectum as feces before being removed by defecation. The colon is the longest portion of the large intestine, and the terms are often used interchangeably but most sources define the large intestine as the combination of the cecum, colon, rectum, and anal canal. Some other sources exclude the anal canal. In humans, the large intestine begins in the right iliac region of the pelvis, just at or below the waist, where it is joined to the end of the small intestine at the cecum, via the ileocecal valve. It then continues as the colon ascending the abdomen, across the width of the abdominal cavity as the transverse colon, and then descending to the rectum and its endpoint at the anal canal. Overall, in humans, the large intestine is about long, which is about one-fifth of ...
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Abdomen
The abdomen (colloquially called the belly, tummy, midriff, tucky or stomach) is the part of the body between the thorax (chest) and pelvis, in humans and in other vertebrates. The abdomen is the front part of the abdominal segment of the torso. The area occupied by the abdomen is called the abdominal cavity. In arthropods it is the posterior (anatomy), posterior tagma (biology), tagma of the body; it follows the thorax or cephalothorax. In humans, the abdomen stretches from the thorax at the thoracic diaphragm to the pelvis at the pelvic brim. The pelvic brim stretches from the lumbosacral joint (the intervertebral disc between Lumbar vertebrae, L5 and Vertebra#Sacrum, S1) to the pubic symphysis and is the edge of the pelvic inlet. The space above this inlet and under the thoracic diaphragm is termed the abdominal cavity. The boundary of the abdominal cavity is the abdominal wall in the front and the peritoneal surface at the rear. In vertebrates, the abdomen is a large body c ...
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Defecation
Defecation (or defaecation) follows digestion, and is a necessary process by which organisms eliminate a solid, semisolid, or liquid waste material known as feces from the digestive tract via the anus. The act has a variety of names ranging from the common, like pooping or crapping, to the technical, e.g. bowel movement, to the obscene ('' shitting''), to the euphemistic ("dropping a deuce" or "taking a dump"). The topic, usually avoided among polite company, can become the basis for some potty humour. Humans expel feces with a frequency varying from a few times daily to a few times weekly. Waves of muscular contraction (known as ''peristalsis'') in the walls of the colon move fecal matter through the digestive tract towards the rectum. Undigested food may also be expelled this way, in a process called ''egestion''. When birds defecate, they also expel urine and urates in the same mass, whereas other animals may also urinate at the same time, but spatially separated. Defeca ...
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Haustra
The haustra (singular haustrum) of the colon are the small pouches caused by sacculation (sac formation), which give the colon its segmented appearance. The teniae coli run the length of the colon. Because the taenia coli are shorter than the colon, the colon becomes sacculated between the teniae coli, forming the haustra. Haustral contractions are slow segmenting, uncoordinated movements that occur approximately every 25 minutes. One haustrum distends as it fills with chyme, which stimulates muscles to contract, pushing the contents to the next haustrum. Also see peristalsis. There is a wider distance between haustra than between the circular folds of the small intestine, and the haustra don't reach around the entire circumference of the intestine, in contrast to circular folds of the small intestine that do. These differences can assist in distinguishing the small intestine from the colon on an abdominal x-ray. Clinical significance Widespread loss of haustra is a sign of ch ...
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Blausen 0604 LargeIntestine2
Blausen Medical Communications, Inc. is the creator and owner of a library of two- and three-dimensional medical and scientific images and animations, a developer of information technology allowing access to that content, and a business focused on licensing and distributing the content. It was founded by Bruce Blausen in Houston, Texas, in 1991, and is privately held. Background Blausen Medical Communications, Inc. (BMC) is a privately held company founded by Bruce Blausen in Houston, Texas in 1991. BMC created and owns a library of medical and scientific images and animations, and has developed information technology tools allowing access to the library; as well, it licenses and otherwise works to distribute the content. As of this date, BMC's animation library comprised approximately 1,500 animations and over 27,000 two- and three-dimensional images designed for point-of-care patient education, which could be accessed by consumers or professional caregivers (primarily via h ...
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Descending Colon
In the anatomy of humans and homologous primates, the descending colon is the part of the colon extending from the left colic flexure to the level of the iliac crest (whereupon it transitions into the sigmoid colon). The function of the descending colon in the digestive system is to store the remains of digested food that will be emptied into the rectum. The descending colon is on the left side of the body (barring any malformations). The term left colon is hypernymous to ''descending colon'' in precise use; many casual mentions of the left colon chiefly concern the descending colon. Structure The descending colon extends from the left colic flexure at the upper left part of the abdomen inferior-ward through the left hypochondrium and lumbar regions, along the outer border of the left kidney, ending at the level of the iliac crest at the lower left part of the abdomen, being contunued thenceforth as the sigmoid colon. It usually retroperitoneal (being lined by peritoneum on ...
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Transverse Colon
In human anatomy, the transverse colon is the longest and most movable part of the colon. Anatomical position It crosses the abdomen from the ascending colon at the right colic flexure (hepatic flexure) with a downward convexity to the descending colon where it curves sharply on itself beneath the lower end of the spleen forming the left colic flexure (splenic flexure). In its course, it describes an arch, the concavity of which is directed backward and a little upward. Toward its splenic end there is often an abrupt U-shaped curve which may descend lower than the main curve. It is almost completely invested by the peritoneum, and is connected to the inferior border of the pancreas by a large and wide duplicature of that membrane, the transverse mesocolon. It is in relation, by its upper surface, with the liver and gall-bladder, the greater curvature of the stomach, and the lower end of the spleen; by its under surface, with the small intestine; by its anterior surface, with t ...
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Abdominal Cavity
The abdominal cavity is a large body cavity in humans and many other animals that contains many organs. It is a part of the abdominopelvic cavity. It is located below the thoracic cavity, and above the pelvic cavity. Its dome-shaped roof is the thoracic diaphragm, a thin sheet of muscle under the lungs, and its floor is the pelvic inlet, opening into the pelvis. Structure Organs Organs of the abdominal cavity include the stomach, liver, gallbladder, spleen, pancreas, small intestine, kidneys, large intestine, and adrenal glands. Peritoneum The abdominal cavity is lined with a protective membrane termed the peritoneum. The inside wall is covered by the parietal peritoneum. The kidneys are located behind the peritoneum, in the retroperitoneum, outside the abdominal cavity. The viscera are also covered by visceral peritoneum. Between the visceral and parietal peritoneum is the peritoneal cavity, which is a potential space. It contains a serous fluid called peritoneal fluid tha ...
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Ascending Colon
''Ascending'' is a science fiction novel by the Canadian writer James Alan Gardner, published in 2001 by HarperCollins Publishers under its various imprints.HarperCollins, Avon, HarperCollins Canada, SFBC/Avon; paperback edition 2001, Eos Books. It is the fifth novel in Gardner's "League of Peoples" series. It is a direct sequel to the first novel in the series, ''Expendable'', in that it picks up the dual story of Festina Ramos, Explorer turned admiral, and the transparent glass woman Oar, where the earlier novel left off. Backstory Through the course of ''Ascending'', Gardner adds depth, detail, and perspective to the conceptual background he has established for the "League of Peoples" series. In particular, he explains how human beings and other species in the galaxy are contacted by, and become a part of, the larger galactic community. Sometime in the middle of the 21st century, humanity encounters a mysterious group of beings who call themselves merely "citizens of the Leag ...
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Ileocecal Valve
The ileocecal valve (ileal papilla, ileocaecal valve, Tulp's valve, Tulpius valve, Bauhin's valve, ileocecal eminence, valve of Varolius or colic valve) is a sphincter muscle valve that separates the small intestine and the large intestine. Its critical function is to limit the reflux of colonic contents into the ileum. Approximately two liters of fluid enters the colon daily through the ileocecal valve. Microanatomy The histology of the ileocecal valve shows an abrupt change from a villous mucosa pattern of the ileum to a more colonic mucosa. A thickening of the muscularis mucosa, which is the smooth muscle tissue found beneath the mucosal layer of the digestive tract. A thickening of the muscularis externa is also noted. There is also a variable amount of lymphatic tissue found at the valve. The ileocecal valve has a papillose structure. Clinical significance Colonoscopy During colonoscopy, the ileocecal valve is used, along with the appendiceal orifice, in the identifi ...
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Waist
The waist is the part of the abdomen between the rib cage and hips. On people with slim bodies, the waist is the narrowest part of the torso. ''Waistline'' refers to the horizontal line where the waist is narrowest, or to the general appearance of the waist. Structure Because of this and because the waist is often synonymous with the stomach, one can become confused as to the exact location of the waist. Another confusing factor is that the waistline differs on different people. A study showed that self-reported measurements as opposed to measurement done by a technician, underestimated waist circumference and this underestimation increased with increased body size. In the study, waist circumference measured at the level of the umbilicus was larger than that measured at the natural waist. To locate the natural waistline, one need simply stand upright and then tilt over to the side keeping the legs and hips straight. Where the torso creases is the natural waistline. Waist me ...
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Pelvis
The pelvis (plural pelves or pelvises) is the lower part of the trunk, between the abdomen and the thighs (sometimes also called pelvic region), together with its embedded skeleton (sometimes also called bony pelvis, or pelvic skeleton). The pelvic region of the trunk includes the bony pelvis, the pelvic cavity (the space enclosed by the bony pelvis), the pelvic floor, below the pelvic cavity, and the perineum, below the pelvic floor. The pelvic skeleton is formed in the area of the back, by the sacrum and the coccyx and anteriorly and to the left and right sides, by a pair of hip bones. The two hip bones connect the spine with the lower limbs. They are attached to the sacrum posteriorly, connected to each other anteriorly, and joined with the two femurs at the hip joints. The gap enclosed by the bony pelvis, called the pelvic cavity, is the section of the body underneath the abdomen and mainly consists of the reproductive organs (sex organs) and the rectum, while the pelvic f ...
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Iliac Region
The ilium () (plural ilia) is the uppermost and largest part of the hip bone, and appears in most vertebrates including mammals and birds, but not bony fish. All reptiles have an ilium except snakes, although some snake species have a tiny bone which is considered to be an ilium. The ilium of the human is divisible into two parts, the body and the wing; the separation is indicated on the top surface by a curved line, the arcuate line, and on the external surface by the margin of the acetabulum. The name comes from the Latin (''ile'', ''ilis''), meaning "groin" or "flank". Structure The ilium consists of the body and wing. Together with the ischium and pubis, to which the ilium is connected, these form the pelvic bone, with only a faint line indicating the place of union. The body ( la, corpus) forms less than two-fifths of the acetabulum; and also forms part of the acetabular fossa. The internal surface of the body is part of the wall of the lesser pelvis and gives origi ...
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