Cerebrocerebellum
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Cerebrocerebellum
The anatomy of the cerebellum can be viewed at three levels. At the level of gross anatomy, the cerebellum consists of a tightly folded and crumpled layer of cortex, with white matter underneath, several deep nuclei embedded in the white matter, and a fluid-filled ventricle in the middle. At the intermediate level, the cerebellum and its auxiliary structures can be broken down into several hundred or thousand independently functioning modules or compartments known as microzones. At the microscopic level, each module consists of the same small set of neuronal elements, laid out with a highly stereotyped geometry. Gross anatomy The cerebellum is located at the base of the brain, with the large mass of the cerebral cortex above it and the portion of the brainstem called the pons in front of it. It is separated from the overlying cerebrum by a layer of tough dura mater; all of its connections with other parts of the brain travel through the pons. Anatomists classify the cerebellu ...
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Cerebellum
The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as or even larger. In humans, the cerebellum plays an important role in motor control. It may also be involved in some cognition, cognitive functions such as attention and language as well as emotion, emotional control such as regulating fear and pleasure responses, but its movement-related functions are the most solidly established. The human cerebellum does not initiate movement, but contributes to Motor coordination, coordination, precision, and accurate timing: it receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity. Cerebellar damage produces disorders in Fine motor skill, fine movement, Equilibrioception, equilibrium, Human positions, posture, and motor learning in humans. Anatomica ...
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Cerebellar Cortex
The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as or even larger. In humans, the cerebellum plays an important role in motor control. It may also be involved in some cognitive functions such as attention and language as well as emotional control such as regulating fear and pleasure responses, but its movement-related functions are the most solidly established. The human cerebellum does not initiate movement, but contributes to coordination, precision, and accurate timing: it receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity. Cerebellar damage produces disorders in fine movement, equilibrium, posture, and motor learning in humans. Anatomically, the human cerebellum has the appearance of a separate structure attached to the bottom ...
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Microzone
The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as or even larger. In humans, the cerebellum plays an important role in motor control. It may also be involved in some cognitive functions such as attention and language as well as emotional control such as regulating fear and pleasure responses, but its movement-related functions are the most solidly established. The human cerebellum does not initiate movement, but contributes to coordination, precision, and accurate timing: it receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity. Cerebellar damage produces disorders in fine movement, equilibrium, posture, and motor learning in humans. Anatomically, the human cerebellum has the appearance of a separate structure attached to the bott ...
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Cerebellar Vermis
The cerebellar vermis (from Latin ''vermis,'' "worm") is located in the medial, cortico-nuclear zone of the cerebellum, which is in the posterior fossa of the cranium. The primary fissure in the vermis curves ventrolaterally to the superior surface of the cerebellum, dividing it into anterior and posterior lobes. Functionally, the vermis is associated with bodily posture and locomotion. The vermis is included within the spinocerebellum and receives somatic sensory input from the head and proximal body parts via ascending spinal pathways. The cerebellum develops in a rostro-caudal manner, with rostral regions in the midline giving rise to the vermis, and caudal regions developing into the cerebellar hemispheres. By 4 months of prenatal development, the vermis becomes fully foliated, while development of the hemispheres lags by 30–60 days. Postnatally, proliferation and organization of the cellular components of the cerebellum continues, with completion of the f ...
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Pons
The pons (from Latin , "bridge") is part of the brainstem that in humans and other bipeds lies inferior to the midbrain, superior to the medulla oblongata and anterior to the cerebellum. The pons is also called the pons Varolii ("bridge of Varolius"), after the Italian anatomist and surgeon Costanzo Varolio (1543–75). This region of the brainstem includes neural pathways and tracts that conduct signals from the brain down to the cerebellum and medulla, and tracts that carry the sensory signals up into the thalamus.Saladin Kenneth S.(2007) Anatomy & physiology the unity of form and function. Dubuque, IA: McGraw-Hill Structure The pons is in the brainstem situated between the midbrain and the medulla oblongata, and in front of the cerebellum. A separating groove between the pons and the medulla is the inferior pontine sulcus. The superior pontine sulcus separates the pons from the midbrain. The pons can be broadly divided into two parts: the basilar part of the pons (ventral ...
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Neuron
A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. Non-animals like plants and fungi do not have nerve cells. Neurons are typically classified into three types based on their function. Sensory neurons respond to stimuli such as touch, sound, or light that affect the cells of the sensory organs, and they send signals to the spinal cord or brain. Motor neurons receive signals from the brain and spinal cord to control everything from muscle contractions to glandular output. Interneurons connect neurons to other neurons within the same region of the brain or spinal cord. When multiple neurons are connected together, they form what is called a neural circuit. A typical neuron consists of a cell body (soma), dendrites, and a single axon. The soma is a compact structure, and the axon and dend ...
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Optic Nerve
In neuroanatomy, the optic nerve, also known as the second cranial nerve, cranial nerve II, or simply CN II, is a paired cranial nerve that transmits visual system, visual information from the retina to the brain. In humans, the optic nerve is derived from optic stalks during the seventh week of development and is composed of retinal ganglion cell axons and glial cells; it extends from the optic disc to the optic chiasma and continues as the optic tract to the lateral geniculate nucleus, Pretectal area, pretectal nuclei, and superior colliculus. Structure The optic nerve has been classified as the second of twelve paired cranial nerves, but it is technically part of the central nervous system, rather than the peripheral nervous system because it is derived from an out-pouching of the diencephalon (optic stalks) during embryonic development. As a consequence, the fibers of the optic nerve are covered with myelin produced by oligodendrocytes, rather than Schwann cells of the per ...
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White Matter
White matter refers to areas of the central nervous system (CNS) that are mainly made up of myelinated axons, also called tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution of action potentials, acting as a relay and coordinating communication between different brain regions. White matter is named for its relatively light appearance resulting from the lipid content of myelin. However, the tissue of the freshly cut brain appears pinkish-white to the naked eye because myelin is composed largely of lipid tissue veined with capillaries. Its white color in prepared specimens is due to its usual preservation in formaldehyde. Structure White matter White matter is composed of bundles, which connect various grey matter areas (the locations of nerve cell bodies) of the brain to each other, and carry nerve impulses between neurons. Myelin acts as an insulator, which allows electrical signals to jump, rather than c ...
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Arbor Vitae (anatomy)
The arbor vitae (Latin for "tree of life") is the cerebellar white matter, so called for its branched, tree-like appearance. In some ways it more resembles a fern and is present in both cerebellar hemispheres. It brings sensory and motor information to and from the cerebellum. The arbor vitae is located deep in the cerebellum. Situated within the arbor vitae are the deep cerebellar nuclei; the dentate, globose, emboliform and the fastigial nuclei. These four different structures lead to the efferent projections of the cerebellum. Related Godfrey Blount's 1899 book ''Arbor Vitae'' was ‘a book on the nature and development of imaginative design for the use of teachers and craftsmen’.Blount, Arbor Vitae, 1899 Additional Images File:Arbor vitae by Sanjoy Sanyal.webm, Dissection video (1 min 14 s). Describing the arbor vitae. File:Midline sagittal view of the brainstem and cerebellum - Arbor vitae.png, Midsagittal section of the brainstem. File:Slide2qq.JPG, Midsagittal sectio ...
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Deep Cerebellar Nuclei
The cerebellum has four deep cerebellar nuclei embedded in the white matter in its center. 4 pairs of nuclei are embedded deep in the medullary centre, in the medial to lateral direction. They are fastigial nuclei, globose nuclei, emboliform nuclei, dentate nuclei. Inputs These nuclei receive inhibitory ( GABAergic) inputs from Purkinje cells in the cerebellar cortex and excitatory (glutamatergic) inputs from mossy fiber and climbing fiber pathways. Most output fibers of the cerebellum originate from these nuclei. One exception is that fibers from the flocculonodular lobe synapse directly on vestibular nuclei without first passing through the deep cerebellar nuclei. The vestibular nuclei in the brainstem are analogous structures to the deep nuclei, since they receive both mossy fiber and Purkinje cell inputs. Specific nuclei From lateral to medial, the four deep cerebellar nuclei are the dentate, emboliform, globose, and fastigii. Some animals, including humans, do not have ...
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Flocculonodular Lobe
The flocculonodular lobe (vestibulocerebellum) is a lobe of the cerebellum consisting of the nodule and the flocculus. The two flocculi are connected to the midline structure called the nodulus by thin pedicles. It is placed on the anteroinferior surface of cerebellum. This region of the cerebellum has important connections to the vestibular nuclei and uses information about head movement to influence eye movement. Lesions to this area can result in multiple deficits in visual tracking and oculomotor control (such as nystagmus and vertigo), integration of vestibular information for eye and head control, as well as control of axial muscles for balance. This lobe is also involved in the maintenance of balance equilibrium and muscle tone. The most common cause of damage to the flocculonodular lobe is medulloblastoma in childhood. References External links NIF Search - Flocculonodular lobevia the Neuroscience Information Framework The Neuroscience Information Framework is a rep ...
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Anterior Lobe Of Cerebellum
The anterior lobe of cerebellum is the portion of the cerebellum responsible for mediating unconscious proprioception. Inputs into the anterior lobe of the cerebellum are mainly from the spinal cord. It is sometimes equated to the "paleocerebellum". Clinical significance Anterior lobe syndrome When a person gets most of their calories from alcohol (chronic alcoholism) the anterior lobe can deteriorate due to malnutrition. This is known as anterior lobe syndrome, and it causes unsteady gait. Additional images File:Anterior lobe of cerebellum -- animation.gif, Animation. Anterior lobe shown in red. File:Anterior lobe of cerebellum --- animation.gif, Close up animation. Anterior lobe shown in red. File:Cerebellar lobes by Sanjoy Sanyal.webm, Dissection video (1 min 20 s). Demonstrating the three cerebellar lobes. References External links * NIF Search - Anterior Lobe of the Cerebellumvia the Neuroscience Information Framework The Neuroscience Information Framework is a r ...
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