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Cerebral Perfusion Pressure
Cerebral perfusion pressure, or CPP, is the net pressure gradient causing cerebral blood flow to the brain (brain perfusion). It must be maintained within narrow limits because too little pressure could cause brain tissue to become ischemic (having inadequate blood flow), and too much could raise intracranial pressure (ICP). Definitions The cranium encloses a fixed-volume space that holds three components: blood, cerebrospinal fluid (CSF), and very soft tissue (the brain). While both the blood and CSF have poor compression capacity, the brain is easily compressible. Every increase of ICP can cause a change in tissue perfusion and an increase in stroke events. From resistance CPP can be defined as the pressure gradient causing cerebral blood flow (CBF) such that : CBF = CPP/CVR where: :CVR is cerebrovascular resistance By intracranial pressure An alternative definition of CPP is: : CPP=MAP-ICP where: :MAP is mean arterial pressure :ICP is intracranial pressure :JVP is jugul ...
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Pressure
Pressure (symbol: ''p'' or ''P'') is the force applied perpendicular to the surface of an object per unit area over which that force is distributed. Gauge pressure (also spelled ''gage'' pressure)The preferred spelling varies by country and even by industry. Further, both spellings are often used ''within'' a particular industry or country. Industries in British English-speaking countries typically use the "gauge" spelling. is the pressure relative to the ambient pressure. Various #Units, units are used to express pressure. Some of these derive from a unit of force divided by a unit of area; the International System of Units, SI unit of pressure, the Pascal (unit), pascal (Pa), for example, is one newton (unit), newton per square metre (N/m2); similarly, the Pound (force), pound-force per square inch (Pounds per square inch, psi) is the traditional unit of pressure in the imperial units, imperial and United States customary units, U.S. customary systems. Pressure may also be e ...
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Interstitial Hydrostatic Pressure
The Starling equation describes the net Fluid dynamics, flow of fluid across a semipermeable membrane. It is named after Ernest Starling. It describes the balance between capillary pressure, interstitial pressure, and osmotic pressure. The classic Starling equation has in recent years been revised. The Starling principle of fluid exchange is key to understanding how Blood plasma, plasma fluid (solvent) within the Circulatory system, bloodstream (intravascular fluid) moves to the space outside the bloodstream (extravascular space). Transendothelial fluid exchange occurs predominantly in the capillaries, and is a process of plasma ultrafiltration across a semi-permeable membrane. It is now appreciated that the ultrafilter is the glycocalyx of the plasma membrane of the endothelium, whose interpolymer spaces function as a system of small pores, radius circa 5 nm. Where the endothelial glycocalyx overlies an inter endothelial cell cleft, the plasma ultrafiltrate may pass to the i ...
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Neurology
Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal cord and the peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system. A neurologist is a physician specializing in neurology and trained to investigate, diagnose and treat neurological disorders. Neurologists treat a myriad of neurologic conditions, including stroke, seizures, movement disorders such as Parkinson's disease, autoimmune neurologic disorders such as multiple sclerosis, headache disorders like migraine and dementias such as Alzheimer's disease. Neurologists may also be involved in clinical research, clinical trials, and basic or translational research. While neurology is a nonsurgical specialty, its corresponding surgical specialty is neurosurger ...
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Medical Terminology
Medical terminology is a language used to precisely describe the human body including all its components, processes, conditions affecting it, and procedures performed upon it. Medical terminology is used in the field of medicine Medical terminology has quite regular morphology, the same prefixes and suffixes are used to add meanings to different roots. The root of a term often refers to an organ, tissue, or condition. For example, in the disorder known as hypertension, the prefix "hyper-" means "high" or "over", and the root word "tension" refers to pressure, so the word "hypertension" refers to abnormally high blood pressure. The roots, prefixes and suffixes are often derived from Greek or Latin, and often quite dissimilar from their English-language variants. This regular morphology means that once a reasonable number of morphemes are learnt it becomes easy to understand very precise terms assembled from these morphemes. Much medical language is anatomical terminology, conc ...
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Physiology (journal)
''Physiology'' is a peer-reviewed scientific journal on physiology published by the American Physiological Society and the International Union of Physiological Societies. Before August 2003, it was named ''News in Physiological Sciences''. The current editor-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The highest-ranking editor of a publication may also be titled editor, managing ... is Gary C. Sieck ( Mayo Clinic). External links * Bimonthly journals English-language journals Publications established in 1986 Physiology journals {{medical-journal-stub ...
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Journal Of Neurology, Neurosurgery, And Psychiatry
The ''Journal of Neurology, Neurosurgery, and Psychiatry'' is a monthly peer-reviewed medical journal published by the BMJ Group. It covers research and reviews in the fields of neurology, neurosurgery, and psychiatry. Its Editor-in-Chief is Matthew Kiernan. (University of Sydney). History The journal was established in 1920 by Samuel Alexander Kinnier Wilson as the ''Journal of Neurology and Psychopathology''. Wilson was the head of a nine-member editorial committee which, besides Wilson, consisted of Thomas Graham Brown, Carey Coombs, Henry Devine, Bernard Hart, Maurice Nicoll, Charles Stanford Read, Roy Mackenzie Stewart, and Charles Symonds. The journal was renamed ''Journal of Neurology and Psychiatry'' from 1938 to 1944, and then obtained its current title. Abstracting and indexing The journal is abstracted and indexed in Web of Science Core Collection: Science Citation Index, Science Citation Index Extended, BIOSIS Previews, Index Medicus/MEDLINE, Current Conten ...
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Traumatic Brain Injury
A traumatic brain injury (TBI), also known as an intracranial injury, is an injury to the brain caused by an external force. TBI can be classified based on severity (ranging from mild traumatic brain injury TBI/concussionto severe traumatic brain injury), mechanism (closed or penetrating head injury), or other features (e.g., occurring in a specific location or over a widespread area). Head injury is a broader category that may involve damage to other structures such as the scalp and skull. TBI can result in physical, cognitive, social, emotional and behavioral symptoms, and outcomes can range from complete recovery to permanent disability or death. Causes include falls, vehicle collisions and violence. Brain trauma occurs as a consequence of a sudden acceleration or deceleration within the cranium or by a complex combination of both movement and sudden impact. In addition to the damage caused at the moment of injury, a variety of events following the injury may result in ...
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Journal Of Cerebral Blood Flow & Metabolism
The ''Journal of Cerebral Blood Flow & Metabolism'' is a monthly peer-reviewed medical journal the official journal of the International Society for Cerebral Blood Flow & Metabolism and publishes peer-reviewed research and review papers. covering research on experimental, theoretical, and clinical aspects of brain circulation, metabolism and imaging. The editor-in-chief is Jun Chen (University of Pittsburgh). According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 6.200. References External links * International Society for Cerebral Blood Flow & Metabolism Neuroscience journals Publications established in 1981 Nature Research academic journals English-language journals Monthly journals Dela ...
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Clinical Autonomic Research
''Clinical Autonomic Research'' is a bimonthly peer-reviewed medical journal covering research on the autonomic nervous system and its disorders. It was established in 1991 and is published by Springer Science+Business Media. The editors-in-chief are Horacio Kaufmann (New York University School of Medicine) and Jens Jordan (German Aerospace Center). It is the official journal of the American Autonomic Society and the European Federation of Autonomic Societies. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 4.435. References External links * Neurology journals Academic journals established in 1991 Bimonthly journals ...
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British Journal Of Anaesthesia
The ''British Journal of Anaesthesia'' is a monthly peer-reviewed medical journal published by Elsevier on behalf of the Royal College of Anaesthetists (and its Faculty of Pain Medicine), the College of Anaesthesiologists of Ireland, and the Hong Kong College of Anaesthesiologists, for all of which it serves as their official journal. The journal covers all aspects of anaesthesia, perioperative medicine, intensive care medicine, and pain management. The editor-in-chief is Hugh C. Hemmings ( Weill Cornell Medical College). The journal was established in 1923, one year after the first anaesthetic journal (''Anesthesia & Analgesia'') was published by the International Anaesthesia Research Society. The first editor-in-chief was H.M. Cohen, who edited the journal from 1923 to 1928. Recent editors-in-chief include Ravi Mahajan (University of Nottingham), Charles Reilly (University of Sheffield), and Jennifer Hunter (University of Liverpool). ''BJA Education'' ''BJA Education'' is ...
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Starling Equation
The Starling equation describes the net Fluid dynamics, flow of fluid across a semipermeable membrane. It is named after Ernest Starling. It describes the balance between capillary pressure, interstitial pressure, and osmotic pressure. The classic Starling equation has in recent years been revised. The Starling principle of fluid exchange is key to understanding how Blood plasma, plasma fluid (solvent) within the Circulatory system, bloodstream (intravascular fluid) moves to the space outside the bloodstream (extravascular space). Transendothelial fluid exchange occurs predominantly in the capillaries, and is a process of plasma ultrafiltration across a semi-permeable membrane. It is now appreciated that the ultrafilter is the glycocalyx of the plasma membrane of the endothelium, whose interpolymer spaces function as a system of small pores, radius circa 5 nm. Where the endothelial glycocalyx overlies an inter endothelial cell cleft, the plasma ultrafiltrate may pass to the i ...
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Brain Cell
Brain cells make up the functional tissue of the brain. The rest of the brain tissue is structural or connective called the stroma which includes blood vessels. The two main types of cells in the brain are neurons, also known as nerve cells, and glial cells also known as neuroglia. Neurons are the excitable cells of the brain that function by communicating with other neurons and interneurons (via synapses), in neural circuits and larger brain networks. The two main neuronal classes in the cerebral cortex are excitatory projection neurons, and inhibitory interneurons; around 70-80 per cent are neurons, and 20-30 per cent inhibitory interneurons. Neurons are often grouped into a cluster known as a nucleus where they usually have roughly similar connections and functions. Nuclei are connected to other nuclei by tracts of white matter. Glia are the supporting cells of the neurons and have many functions not all of which are clearly understood, but include providing support and n ...
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