Cerebral Achromatopsia
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Cerebral Achromatopsia
Cerebral achromatopsia is a type of color-blindness caused by damage to the cerebral cortex of the brain, rather than abnormalities in the cells of the eye's retina. It is often confused with congenital achromatopsia but underlying physiological deficits of the disorders are completely distinct. A similar, but distinct, deficit called color agnosia exists in which a person has intact color perception (as measured by a matching task) but has deficits in color recognition, such as knowing which color they are looking at. Signs and symptoms Patients with cerebral achromatopsia deny having any experience of color when asked and fail standard clinical assessments like the Farnsworth-Munsell 100-hue test (a test of color ordering with no naming requirements). Patients may often not notice their loss of color vision and merely describe the world they see as being "drab". Most describe seeing the world in "shades of gray". This observation notes a key difference between cerebral and cong ...
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Cerebral Cortex
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system. It plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The cerebral cortex is part of the brain responsible for cognition. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the cranium. Apart from minimising brain and cranial volume, cortical folding is crucial for the brain ...
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Oliver Sacks
Oliver Wolf Sacks, (9 July 1933 – 30 August 2015) was a British neurologist, naturalist, historian of science, and writer. Born in Britain, Sacks received his medical degree in 1958 from The Queen's College, Oxford, before moving to the United States, where he spent most of his career. He interned at Mount Zion Hospital in San Francisco and completed his residency in neurology and neuropathology at the University of California, Los Angeles (UCLA). After a fellowship at the Albert Einstein College of Medicine, he served as neurologist at Beth Abraham Hospital's chronic-care facility in the Bronx, where he worked with a group of survivors of the 1920s sleeping sickness encephalitis lethargica, who had been unable to move on their own for decades. His treatment of those patients became the basis of his 1973 book '' Awakenings'', which was adapted into an Academy Award-nominated feature film in 1990, starring Robin Williams and Robert De Niro. His numerous other best-selling ...
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Neuropsychology
Neuropsychology is a branch of psychology concerned with how a person's cognition and behavior are related to the brain and the rest of the nervous system. Professionals in this branch of psychology often focus on how injuries or illnesses of the brain affect cognitive and behavioral functions. It is both an experimental and clinical field of psychology, thus aiming to understand how behavior and cognition are influenced by brain function and concerned with the medical diagnosis, diagnosis and therapy, treatment of behavioral and cognitive effects of neurological disorders. Whereas classical neurology focuses on the pathology of the nervous system and classical psychology is largely divorced from it, neuropsychology seeks to discover how the brain neural correlates of consciousness, correlates with the mind through the study of neurological patients. It thus shares concepts and concerns with neuropsychiatry and with behavioral neurology in general. The term ''neuropsychology'' h ...
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Visual Disturbances And Blindness
The visual system comprises the sensory organ (the eye) and parts of the central nervous system (the retina containing photoreceptor cells, the optic nerve, the optic tract and the visual cortex) which gives organisms the sense of sight (the ability to detect and process visible light) as well as enabling the formation of several non-image photo response functions. It detects and interprets information from the optical spectrum perceptible to that species to "build a representation" of the surrounding environment. The visual system carries out a number of complex tasks, including the reception of light and the formation of monocular neural representations, colour vision, the neural mechanisms underlying stereopsis and assessment of distances to and between objects, the identification of a particular object of interest, motion perception, the analysis and integration of visual information, pattern recognition, accurate motor coordination under visual guidance, and more. Th ...
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Color Vision
Color vision, a feature of visual perception, is an ability to perceive differences between light composed of different wavelengths (i.e., different spectral power distributions) independently of light intensity. Color perception is a part of the larger visual system and is mediated by a complex process between neurons that begins with differential stimulation of different types of photoreceptors by light entering the eye. Those photoreceptors then emit outputs that are propagated through many layers of neurons and then ultimately to the brain. Color vision is found in many animals and is mediated by similar underlying mechanisms with common types of biological molecules and a complex history of evolution in different animal taxa. In primates, color vision may have evolved under selective pressure for a variety of visual tasks including the foraging for nutritious young leaves, ripe fruit, and flowers, as well as detecting predator camouflage and emotional states in other pr ...
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Ishihara Color Test
The Ishihara test is a color vision test for detection of red-green color deficiencies. It was named after its designer, Shinobu Ishihara, a professor at the University of Tokyo, who first published his tests in 1917.S. Ishihara, Tests for color-blindness (Handaya, Tokyo, Hongo Harukicho, 1917). The test consists of a number of Ishihara plates, which are a type of pseudoisochromatic plate. Each plate depicts a solid circle of colored dots appearing randomized in color and size. Within the pattern are dots which form a number or shape clearly visible to those with normal color vision, and invisible, or difficult to see, to those with a red-green color vision defect. Other plates are intentionally designed to reveal numbers only to those with a red-green color vision deficiency, and be invisible to those with normal red-green color vision. The full test consists of 38 plates, but the existence of a severe deficiency is usually apparent after only a few plates. There are also I ...
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Color Blindness
Color blindness or color vision deficiency (CVD) is the decreased ability to color vision, see color or differences in color. It can impair tasks such as selecting ripe fruit, choosing clothing, and reading traffic lights. Color blindness may make some academic activities more difficult. However, issues are generally minor, and the colorblind automatically develop adaptations and coping mechanisms. People with achromatopsia, total color blindness (achromatopsia) may also be Hemeralopia, uncomfortable in bright environments and have visual impairment, decreased visual acuity. The most common cause of color blindness is an Heredity, inherited problem or variation in the functionality of one or more of the three classes of cone cells in the retina, which mediate color vision. The most common form is caused by a genetic disorder called congenital red–green color blindness. Males are more likely to be color blind than females, because the genes responsible for the most common for ...
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Cortical Blindness
Cortical blindness is the total or partial loss of vision in a normal-appearing eye caused by damage to the brain's occipital cortex. Cortical blindness can be acquired or congenital, and may also be transient in certain instances. Acquired cortical blindness is most often caused by loss of blood flow to the occipital cortex from either unilateral or bilateral posterior cerebral artery blockage (ischemic stroke) and by cardiac surgery. In most cases, the complete loss of vision is not permanent and the patient may recover some of their vision (cortical visual impairment). Congenital cortical blindness is most often caused by perinatal ischemic stroke, encephalitis, and meningitis. Rarely, a patient with acquired cortical blindness may have little or no insight that they have lost vision, a phenomenon known as Anton–Babinski syndrome. Cortical blindness and cortical visual impairment (CVI), which refers to the partial loss of vision caused by cortical damage, are both classified a ...
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Achromatopsia
Achromatopsia, also known as Rod monochromacy, is a medical syndrome that exhibits symptoms relating to five conditions, most notably monochromacy. Historically, the name referred to monochromacy in general, but now typically refers only to an autosomal recessive congenital color vision condition. The term is also used to describe cerebral achromatopsia, though monochromacy is usually the only common symptom. The conditions include: monochromatic color blindness, poor visual acuity, and day-blindness. The syndrome is also present in an ''incomplete'' form that exhibits milder symptoms, including residual color vision. Achromatopsia is estimated to affect 1 in 30,000 live births worldwide. Signs and symptoms The five symptoms associated with achromatopsia are: # Color blindness - usually monochromacy # Reduced visual acuity - uncorrectable with lenses # Hemeralopia – with the subject exhibiting photophobia # Nystagmus # Iris operating abnormalities The syndrome is typi ...
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Ishihara Plate
The Ishihara test is a color vision test for detection of red-green color deficiencies. It was named after its designer, Shinobu Ishihara, a professor at the University of Tokyo, who first published his tests in 1917.S. Ishihara, Tests for color-blindness (Handaya, Tokyo, Hongo Harukicho, 1917). The test consists of a number of Ishihara plates, which are a type of pseudoisochromatic plate. Each plate depicts a solid circle of colored dots appearing randomized in color and size. Within the pattern are dots which form a number or shape clearly visible to those with normal color vision, and invisible, or difficult to see, to those with a red-green color vision defect. Other plates are intentionally designed to reveal numbers only to those with a red-green color vision deficiency, and be invisible to those with normal red-green color vision. The full test consists of 38 plates, but the existence of a severe deficiency is usually apparent after only a few plates. There are also Ish ...
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Retina
The retina (from la, rete "net") is the innermost, light-sensitive layer of tissue of the eye of most vertebrates and some molluscs. The optics of the eye create a focused two-dimensional image of the visual world on the retina, which then processes that image within the retina and sends nerve impulses along the optic nerve to the visual cortex to create visual perception. The retina serves a function which is in many ways analogous to that of the film or image sensor in a camera. The neural retina consists of several layers of neurons interconnected by synapses and is supported by an outer layer of pigmented epithelial cells. The primary light-sensing cells in the retina are the photoreceptor cells, which are of two types: rods and cones. Rods function mainly in dim light and provide monochromatic vision. Cones function in well-lit conditions and are responsible for the perception of colour through the use of a range of opsins, as well as high-acuity vision used for task ...
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Color Vision Tests
A color vision test is used for measuring color vision against a standard. These tests are most often used to diagnose color vision deficiencies (''color blindness''), though several of the standards are designed to categorize normal color vision into sub-levels. With the large prevalence of color vision deficiencies (8% of males) and the wide range of professions that restrict hiring the colorblind for safety or aesthetic reasons, clinical color vision standards must be designed to be fast and simple to implement. Color vision standards for academic use trade speed and simplicity for accuracy and precision. Applications Color vision standards are used to evaluate the color vision of a subject. They are most commonly applied to job applicants during pre-job screening. The evaluation may be to select against the color vision deficient for roles where basic color vision is required, or to select for individuals with superior color vision for roles where recognition of subtle colo ...
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