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Corneal Topography
Corneal topography, also known as photokeratoscopy or videokeratography, is a non-invasive medical imaging technique for mapping the anterior curvature of the cornea, the outer structure of the eye. Since the cornea is normally responsible for some 70% of the eye's refractive power, its topography is of critical importance in determining the quality of vision and corneal health. The three-dimensional map is therefore a valuable aid to the examining ophthalmologist or optometrist and can assist in the diagnosis and treatment of a number of conditions; in planning cataract surgery and intraocular lens implantation; in planning refractive surgery such as LASIK, and evaluating its results; or in assessing the fit of contact lenses. A development of keratoscopy, corneal topography extends the measurement range from the four points a few millimeters apart that is offered by keratometry to a grid of thousands of points covering the entire cornea. The procedure is carried out in seconds ...
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Keratoconus
Keratoconus (KC) is a disorder of the eye that results in progressive thinning of the cornea. This may result in blurry vision, double vision, nearsightedness, irregular astigmatism, and light sensitivity leading to poor quality-of-life. Usually both eyes are affected. In more severe cases a scarring or a circle may be seen within the cornea. While the cause is unknown, it is believed to occur due to a combination of genetic, environmental, and hormonal factors. Patients with a parent, sibling, or child who has keratoconus have 15 to 67 times higher risk in developing corneal ectasia compared to patients with no affected relatives. Proposed environmental factors include rubbing the eyes and allergies. The underlying mechanism involves changes of the cornea to a cone shape. Diagnosis is most often by topography. Topography measures the curvature of the cornea and creates a colored "map" of the cornea. Keratoconus causes very distinctive changes in the appearance of these ma ...
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Digital Camera
A digital camera is a camera that captures photographs in digital memory. Most cameras produced today are digital, largely replacing those that capture images on photographic film. Digital cameras are now widely incorporated into mobile devices like smartphones with the same or more capabilities and features of dedicated cameras (which are still available). High-end, high-definition dedicated cameras are still commonly used by professionals and those who desire to take higher-quality photographs. Digital and digital movie cameras share an optical system, typically using a lens with a variable diaphragm to focus light onto an image pickup device. The diaphragm and shutter admit a controlled amount of light to the image, just as with film, but the image pickup device is electronic rather than chemical. However, unlike film cameras, digital cameras can display images on a screen immediately after being recorded, and store and delete images from memory. Many digital cameras can ...
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Keratoconus
Keratoconus (KC) is a disorder of the eye that results in progressive thinning of the cornea. This may result in blurry vision, double vision, nearsightedness, irregular astigmatism, and light sensitivity leading to poor quality-of-life. Usually both eyes are affected. In more severe cases a scarring or a circle may be seen within the cornea. While the cause is unknown, it is believed to occur due to a combination of genetic, environmental, and hormonal factors. Patients with a parent, sibling, or child who has keratoconus have 15 to 67 times higher risk in developing corneal ectasia compared to patients with no affected relatives. Proposed environmental factors include rubbing the eyes and allergies. The underlying mechanism involves changes of the cornea to a cone shape. Diagnosis is most often by topography. Topography measures the curvature of the cornea and creates a colored "map" of the cornea. Keratoconus causes very distinctive changes in the appearance of these ma ...
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Cross-linking (surgery)
Corneal cross-linking (CXL) with riboflavin (vitamin B2) and UV-A light is a surgical treatment for corneal ectasia such as keratoconus, PMD, and post-LASIK ectasia. It is used in an attempt to make the cornea stronger. According to a 2015 Cochrane review, there is insufficient evidence to determine if it is useful in keratoconus. In 2016, the US Food and Drug Administration approved riboflavin ophthalmic solution crosslinking based on three 12-month clinical trials. Medical uses A 2015 Cochrane review found that the evidence on corneal cross-linking was insufficient to determine if it is an effective procedure for the treatment of keratoconus. Adverse effects Among those with keratoconus who worsen CXL may be used. In this group, the most common side effects are haziness of the cornea, punctate keratitis, corneal striae, corneal epithelium defect, and eye pain. In those who use it after post-LASIK ectasia, the most common side effects are haziness of the cornea, corn ...
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Corneal Topography, Stage II Keratoconus (Elise A
The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Along with the anterior chamber and lens, the cornea refracts light, accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is approximately 43 dioptres. The cornea can be reshaped by surgical procedures such as LASIK. While the cornea contributes most of the eye's focusing power, its focus is fixed. Accommodation (the refocusing of light to better view near objects) is accomplished by changing the geometry of the lens. Medical terms related to the cornea often start with the prefix "'' kerat-''" from the Greek word κέρας, ''horn''. Structure The cornea has unmyelinated nerve endings sensitive to touch, temperature and chemicals; a touch of the cornea causes an involuntary reflex to close the eyelid. Because transparency is of prime importance, the healthy cornea does not have or need blood vessels within i ...
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Clinic
A clinic (or outpatient clinic or ambulatory care clinic) is a health facility that is primarily focused on the care of outpatients. Clinics can be privately operated or publicly managed and funded. They typically cover the primary care needs of populations in local communities, in contrast to larger hospitals which offer more specialised treatments and admit inpatients for overnight stays. Most commonly, the English word clinic refers to a general practice, run by one or more general practitioners offering small therapeutic treatments, but it can also mean a specialist clinic. Some clinics retain the name "clinic" even while growing into institutions as large as major hospitals or becoming associated with a hospital or medical school. Etymology The word ''clinic'' derives from Ancient Greek ''klinein'' meaning to slope, lean or recline. Hence ''klinē'' is a couch or bed and ''klinikos'' is a physician who visits his patients in their beds. In Latin, this became ''clī ...
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Algorithm
In mathematics and computer science, an algorithm () is a finite sequence of rigorous instructions, typically used to solve a class of specific Computational problem, problems or to perform a computation. Algorithms are used as specifications for performing calculations and data processing. More advanced algorithms can perform automated deductions (referred to as automated reasoning) and use mathematical and logical tests to divert the code execution through various routes (referred to as automated decision-making). Using human characteristics as descriptors of machines in metaphorical ways was already practiced by Alan Turing with terms such as "memory", "search" and "stimulus". In contrast, a Heuristic (computer science), heuristic is an approach to problem solving that may not be fully specified or may not guarantee correct or optimal results, especially in problem domains where there is no well-defined correct or optimal result. As an effective method, an algorithm ca ...
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Ophthalmoscope
Ophthalmoscopy, also called funduscopy, is a test that allows a health professional to see inside the fundus of the eye and other structures using an ophthalmoscope (or funduscope). It is done as part of an eye examination and may be done as part of a routine physical examination. It is crucial in determining the health of the retina, optic disc, and vitreous humor. The pupil is a hole through which the eye's interior will be viewed. Opening the pupil wider (dilating it) is a simple and effective way to better see the structures behind it. Therefore, dilation of the pupil ( mydriasis) is often accomplished with medicated eye drops before funduscopy. However, although dilated fundus examination is ideal, undilated examination is more convenient and is also helpful (albeit not as comprehensive), and it is the most common type in primary care. An alternative or complement to ophthalmoscopy is to perform a fundus photography, where the image can be analysed later by a professional. ...
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Allvar Gullstrand
Allvar Gullstrand (5 June 1862 – 28 July 1930) was a Swedish ophthalmologist and optician. Life Born at Landskrona, Sweden, Gullstrand was professor (1894–1927) successively of eye therapy and of optics at the University of Uppsala. He applied the methods of physical mathematics to the study of optical images and of the refraction of light in the eye. For this work, he received the Nobel Prize in Physiology or Medicine in 1911. Gullstrand is noted also for his research on astigmatism and for improving the ophthalmoscope and corrective lenses for use after removal of a cataract from the eye. He was elected a member of the Royal Swedish Academy of Sciences in 1905, and served on the Academy's Prize Committee for Physics. While serving on the committee, he used his position to block Albert Einstein from receiving a Nobel Prize in Physics for his theory of relativity, which Allvar believed to be wrong. Gullstrand married Signe Breitholtz (1862–1946) in 1885. Due to the ma ...
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Louis Émile Javal
Louis Émile Javal (May 5, 1839 – January 20, 1907) was a French ophthalmologist born in Paris. Javal is remembered for his studies of physiological optics and his work involving a disorder known as strabismus. Early life He was born in Paris to Léopold Javal (1804-1872) and Auguste Javal (née von Lämel; 1817-1893). Academic background Originally trained as a civil engineer, he switched to the medical profession, receiving his degree from the University of Paris in 1868. Following graduation, he traveled to Berlin, where he studied under Albrecht von Graefe (1828-1870). During the Franco-Prussian War he served as a medical officer. In 1878 he opened an ophthalmological laboratory at the Sorbonne and was its director until 1900. Like his father politically active, he represented the district of Yonne in the French Parliament from 1884 to 1889. Contributions in ophthalmology With his student Hjalmar August Schiøtz (1850-1927), he constructed an early keratom ...
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Contour Line
A contour line (also isoline, isopleth, or isarithm) of a function of two variables is a curve along which the function has a constant value, so that the curve joins points of equal value. It is a plane section of the three-dimensional graph of the function f(x,y) parallel to the (x,y)-plane. More generally, a contour line for a function of two variables is a curve connecting points where the function has the same particular value. In cartography, a contour line (often just called a "contour") joins points of equal elevation (height) above a given level, such as mean sea level. A contour map is a map illustrated with contour lines, for example a topographic map, which thus shows valleys and hills, and the steepness or gentleness of slopes. The contour interval of a contour map is the difference in elevation between successive contour lines. The gradient of the function is always perpendicular to the contour lines. When the lines are close together the magnitude of the grad ...
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Antonio Placido
Antonio is a masculine given name of Etruscan origin deriving from the root name Antonius. It is a common name among Romance language-speaking populations as well as the Balkans and Lusophone Africa. It has been among the top 400 most popular male baby names in the United States since the late 19th century and has been among the top 200 since the mid 20th century. In the English language it is translated as Anthony, and has some female derivatives: Antonia, Antónia, Antonieta, Antonietta, and Antonella'. It also has some male derivatives, such as Anthonio, Antón, Antò, Antonis, Antoñito, Antonino, Antonello, Tonio, Tono, Toño, Toñín, Tonino, Nantonio, Ninni, Totò, Tó, Tonini, Tony, Toni, Toninho, Toñito, and Tõnis. The Portuguese equivalent is António (Portuguese orthography) or Antônio (Brazilian Portuguese). In old Portuguese the form Antão was also used, not just to differentiate between older and younger but also between more and less important. In Galician the ...
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