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Clonorchiasis
Clonorchiasis is an infectious disease caused by the Chinese liver fluke (''Clonorchis sinensis'') and two related species. Clonorchiasis is a known risk factor for the development of cholangiocarcinoma, a neoplasm of the biliary system. Symptoms of opisthorchiasis caused by ''Opisthorchis viverrini'' and by '' O. felineus'' are indistinguishable from clonorchiasis caused by ''Clonorchis sinensis'', leading some to argue that the disease by these three parasites should be referred to collectively as clonorchiasis.. Signs and symptoms Cause ''Clonorchiasis sinensis'' is a trematode (fluke) which is part of the phylum Platyhelminthes. The parasitic worm is as long as 10 to 25 mm and lives in the bile ducts of the liver. It is a hermaphroditic fluke that requires two intermediate hosts. The eggs of the worms are passed in fecal matter into a body of water and are then ingested by mollusks. The water snail is the first intermediate host, in which a miracidium (an embryonate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clonorchis Sinensis
''Clonorchis sinensis'', the Chinese liver fluke, is a liver fluke belonging to the class Trematoda, phylum Platyhelminthes. It infects fish-eating mammals, including humans. In humans, it infects the common bile duct and gall bladder, feeding on bile. It was discovered by British physician James McConnell at the Medical College Hospital in Calcutta (Kolkata) in 1874. The first description was given by Thomas Spencer Cobbold, who named it ''Distoma sinense''. The fluke passes its lifecycle in three different hosts, namely freshwater snail as first intermediate hosts, freshwater fish as second intermediate host, and mammals as definitive hosts. Endemic to Asia and Russia, ''C. sinensis'' is the most prevalent human fluke in Asia and third-most in the world. It is still actively transmitted in Korea, China, Vietnam, and Russia. Most infections (about 85%) occur in China. The infection, called clonorchiasis, generally appears as jaundice, indigestion, biliary inflammation, bile duct ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Helminthiases
Helminthiasis, also known as worm infection, is any macroparasitic disease of humans and other animals in which a part of the body is infected with parasitic worms, known as helminths. There are numerous species of these parasites, which are broadly classified into tapeworms, flukes, and roundworms. They often live in the gastrointestinal tract of their hosts, but they may also burrow into other organs, where they induce physiological damage. Soil-transmitted helminthiasis and schistosomiasis are the most important helminthiases, and are among the neglected tropical diseases. These group of helminthiases have been targeted under the joint action of the world's leading pharmaceutical companies and non-governmental organizations through a project launched in 2012 called the London Declaration on Neglected Tropical Diseases, which aims to control or eradicate certain neglected tropical diseases by 2020. Helminthiasis has been found to result in poor birth outcome, poor cogniti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Praziquantel
Praziquantel (PZQ), sold under the brandname Biltricide among others, is a medication used to treat a number of types of helminthiasis, parasitic worm infections in mammals, birds, amphibians, reptiles, and fish. In humans specifically, it is used to treat schistosomiasis, clonorchiasis, opisthorchiasis, Taeniasis, tapeworm infections, cysticercosis, echinococcosis, paragonimiasis, fasciolopsiasis, and fasciolosis. It should not be used for worm infections of the eye. It is taken Oral administration, by mouth. Side effects in humans may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions. While it may be used during pregnancy, it is not recommended for use during breastfeeding. Praziquantel is in the anthelmintic class of medications. It works partly by affecting the function of the worm's Sucker (zoology), sucker. Praziquantel was approved for medical use in the United States in 1982. It is on the WHO Model List of Essential Medicines, World ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Infectious Disease
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune system. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Specific medications used to treat infections include antibiotics, antivirals, antifungals, antiprotozoals, and antihelminthics. Infectious diseases resulted in 9.2 million deaths in 2013 (about 17% of all deaths). The branch of medicine that focuses on infections is referred to as infectious disease. Types Infections are caused by infectious agents (pathogens) including: * Bacteria (e.g. '' Mycobacterium tuberculosis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hepatology
Hepatology is the branch of medicine that incorporates the study of liver, gallbladder, biliary tree, and pancreas as well as management of their disorders. Although traditionally considered a sub-specialty of gastroenterology, rapid expansion has led in some countries to doctors specializing solely on this area, who are called hepatologists. Diseases and complications related to viral hepatitis and alcohol are the main reason for seeking specialist advice. More than two billion people have been infected with hepatitis B virus at some point in their life, and approximately 350 million have become persistent carriers. Up to 80% of liver cancers can be attributed to either hepatitis B or hepatitis C virus. In terms of mortality, the former is second only to smoking among known agents causing cancer. With more widespread implementation of vaccination and strict screening before blood transfusion, lower infection rates are expected in the future. In many countries, however, overall ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metacercariae
Trematodes are parasitic flatworms of the class ''Trematoda'', specifically parasitic flukes with two suckers: one ventral and the other oral. Trematodes are covered by a tegument, that protects the organism from the environment by providing secretory and absorptive functions. The life cycle of a typical trematode begins with an egg. Some trematode eggs hatch directly in the environment (water), while others are eaten and hatched within a host, typically a mollusc. The hatchling is called a ''miracidium,'' a free-swimming, ciliated larva. Miracidia will then grow and develop within the intermediate host into a sac-like structure known as a sporocyst or into rediae, either of which may give rise to free-swimming, motile cercariae larvae. The cercariae then could either infect a vertebrate host or a second intermediate host. Adult metacercariae or mesocercariae, depending on the individual trematode's life cycle, will then infect the vertebrate host or be rejected and excreted thro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Far East
The ''Far East'' was a European term to refer to the geographical regions that includes East and Southeast Asia as well as the Russian Far East to a lesser extent. South Asia is sometimes also included for economic and cultural reasons. The term first came into use in European geopolitical discourse in the 15th century, particularly the British, denoting the Far East as the "farthest" of the three "Easts", beyond the Near East and the Middle East. Likewise, during the Qing dynasty of the 19th and early 20th centuries, the term "Far West (Taixi), Tàixī ()" – i.e., anything further west than the Arab world – was used to refer to the Western countries. Since the mid-20th century, the term has mostly gone out of use for the region in international mass media outlets due to its eurocentric connotations.Reischauer, Edwin and John K Fairbank, ''East Asia: The Great Tradition,'' 1960. The Russian Far East is often excluded due to cultural and ethnic differences, and is often cons ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endemic
Endemism is the state of a species being found in a single defined geographic location, such as an island, state, nation, country or other defined zone; organisms that are indigenous to a place are not endemic to it if they are also found elsewhere. For example, the Cape sugarbird is found exclusively in southwestern South Africa and is therefore said to be ''endemic'' to that particular part of the world. An endemic species can be also be referred to as an ''endemism'' or in scientific literature as an ''endemite''. For example '' Cytisus aeolicus'' is an endemite of the Italian flora. '' Adzharia renschi'' was once believed to be an endemite of the Caucasus, but it was later discovered to be a non-indigenous species from South America belonging to a different genus. The extreme opposite of an endemic species is one with a cosmopolitan distribution, having a global or widespread range. A rare alternative term for a species that is endemic is "precinctive", which applies to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cercaria
A cercaria (plural cercariae) is the larval form of the trematode class of parasites. It develops within the germinal cells of the sporocyst or redia. A cercaria has a tapering head with large penetration glands. It may or may not have a long swimming "tail", depending on the species. The motile cercaria finds and settles in a host where it will become either an adult, or a mesocercaria, or a metacercaria, according to species. Rotifers (''Rotaria Rotaria is a genus of asexual, microscopic animal known as a bdelloid rotifer. Analysis published in 2007 of morphology and DNA sequence data of species form the genus confirmed that despite their asexual mechanism of reproduction, two fundame ... rotatoria'') produce a chemical, Schistosome Paralysis Factor, suppressing cercaria swimming and reducing infections.{{cite journal , editor1-last=Khosla , editor1-first=Chaitan , last1=Gao, first1=Jiarong, last2=Yang, first2=Ning, last3=Lewis, first3=Fred A., last4=Yau, first4=Peter, la ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Freshwater Fish
Freshwater fish are those that spend some or all of their lives in fresh water, such as rivers and lakes, with a salinity of less than 1.05%. These environments differ from marine conditions in many ways, especially the difference in levels of salinity. To survive fresh water, the fish need a range of physiology, physiological adaptations. 41.24% of all known species of fish are found in fresh water. This is primarily due to the rapid speciation that the scattered habitats make possible. When dealing with ponds and lakes, one might use the same basic models of speciation as when studying island biogeography. Physiology Freshwater fish differ physiologically from salt water fish in several respects. Their gills must be able to diffuse dissolved gases while keeping the salts in the body fluids inside. Their scales reduce water diffusion through the skin: freshwater fish that have lost too many scales will die. They also have well developed kidneys to reclaim salts from body flui ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trematode Life Cycle Stages
Trematodes are parasitic flatworms of the class ''Trematoda'', specifically parasitic flukes with two suckers: one ventral and the other oral. Trematodes are covered by a tegument, that protects the organism from the environment by providing secretory and absorptive functions. The life cycle of a typical trematode begins with an egg. Some trematode eggs hatch directly in the environment (water), while others are eaten and hatched within a host, typically a mollusc. The hatchling is called a ''miracidium,'' a free-swimming, ciliated larva. Miracidia will then grow and develop within the intermediate host into a sac-like structure known as a sporocyst or into rediae, either of which may give rise to free-swimming, motile cercariae larvae. The cercariae then could either infect a vertebrate host or a second intermediate host. Adult metacercariae or mesocercariae, depending on the individual trematode's life cycle, will then infect the vertebrate host or be rejected and excreted thro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Miracidium
The Miracidium is the second stage in the life cycle of trematodes. When trematode eggs are laid and come into contact with fresh water, they hatch and release miracidium. In this phase, miracidia are ciliated and free-swimming. This stage is completed upon coming in contact with, and entering into, a suitable intermediate host for the purposes of asexual reproduction. Many different species of ''Trematoda'' exist, expressing some variation in the physiology and appearance of the miracidia. The various trematode species implement similar strategies to increase their chances of locating and colonizing a new host. Anatomy ''Hirundinella ventricosa'' The trematode ''Hirundinella ventricosa'' releases eggs in strings. Each egg contains a single miracidium, while the string contains living spermatozoa. Miracidia have cilia that are only present in the upper portion of the body near an apical gland with 12 hook-like spines in the opening. ''Echinostoma paraensei'' Miracidia usu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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