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Central Auditory System
The auditory system is the sensory system for the sense of hearing. It includes both the sensory organs (the ears) and the auditory parts of the sensory system. System overview The outer ear funnels sound vibrations to the eardrum, increasing the sound pressure in the middle frequency range. The middle-ear ossicles further amplify the vibration pressure roughly 20 times. The base of the stapes couples vibrations into the cochlea via the oval window, which vibrates the perilymph liquid (present throughout the inner ear) and causes the round window to bulb out as the oval window bulges in. Vestibular and tympanic ducts are filled with perilymph, and the smaller cochlear duct between them is filled with endolymph, a fluid with a very different ion concentration and voltage. Vestibular duct perilymph vibrations bend organ of Corti outer cells (4 lines) causing prestin to be released in cell tips. This causes the cells to be chemically elongated and shrunk ( somatic motor), and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journey Of Sound To The Brain
Journey or journeying may refer to: * Travel, the movement of people between distant geographical locations ** Day's journey, a measurement of distance ** Road trip, a long-distance journey on the road Animals * Journey (horse), a thoroughbred racehorse * Journey (wolf) or OR-7, a gray wolf being electronically tracked in the Northwest United States Arts, entertainment, and media Films * ''Journey'' (1972 film), a 1972 Canadian film directed by Paul Almond * ''Journey'' (1995 film), a 1995 Hallmark Hall of Fame TV film * ''Journey'' (2004 film), a 2004 short film written and directed by Christine Shin * ''Journey'', a Telugu dubbed movie of original Tamil movie ''Engaeyum Eppothum'' Literature * ''Journey'' (novel), a 1989 historical novel by James Michener * ''A Journey'' (2010), Tony Blair's memoirs * ''Journey'' (picture book), a 2013 children's book by Aaron Becker * '' Journey: The Adventures of Wolverine MacAlistaire'', a 1983 comic by William Messner-Loebs Music ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endolymph
Endolymph is the fluid contained in the membranous labyrinth of the inner ear. The major cation in endolymph is potassium, with the values of sodium and potassium concentration in the endolymph being 0.91 mM and 154 mM, respectively. It is also called ''Scarpa's fluid'', after Antonio Scarpa. Structure The inner ear has two parts: the bony labyrinth and the membranous labyrinth. The membranous labyrinth is contained within the bony labyrinth, and within the membranous labyrinth is a fluid called endolymph. Between the outer wall of the membranous labyrinth and the wall of the bony labyrinth is the location of perilymph. Composition Perilymph and endolymph have unique ionic compositions suited to their functions in regulating electrochemical impulses of hair cells. The electric potential of endolymph is ~80-90 mV more positive than perilymph due to a higher concentration of K compared to Na. The main component of this unique extracellular fluid is potassium, which is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Olivary Complex
In anatomy, the olivary bodies or simply olives (Latin ''oliva'' and ''olivae'', singular and plural, respectively) are a pair of prominent oval structures in the medulla oblongata, the lower portion of the brainstem. They contain the olivary nuclei. Structure The olivary body is located on the anterior surface of the medulla lateral to the pyramid, from which it is separated by the antero-lateral sulcus and the fibers of the hypoglossal nerve. Behind ( dorsally), it is separated from the postero-lateral sulcus by the ventral spinocerebellar fasciculus. In the depression between the upper end of the olive and the pons lies the vestibulocochlear nerve. In humans, it measures about 1.25 cm. in length, and between its upper end and the pons there is a slight depression to which the roots of the facial nerve are attached. The external arcuate fibers wind across the lower part of the pyramid and olive and enter the inferior peduncle. Olivary nuclei The olive consists of two ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Superior Olivary Complex
The superior olivary complex (SOC) or superior olive is a collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system. The SOC is intimately related to the trapezoid body: most of the cell groups of the SOC are dorsal (posterior in primates) to this axon bundle while a number of cell groups are embedded in the trapezoid body. Overall, the SOC displays a significant interspecies variation, being largest in bats and rodents and smaller in primates. Physiology The superior olivary nucleus plays a number of roles in hearing. The medial superior olive (MSO) is a specialized nucleus that is believed to measure the time difference of arrival of sounds between the ears (the interaural time difference or ITD). The ITD is a major cue for determining the azimuth of sounds, i.e., localising them on the azimuthal plane – their degree to the left or the right. The lateral ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pons
The pons (from Latin , "bridge") is part of the brainstem that in humans and other bipeds lies inferior to the midbrain, superior to the medulla oblongata and anterior to the cerebellum. The pons is also called the pons Varolii ("bridge of Varolius"), after the Italian anatomist and surgeon Costanzo Varolio (1543–75). This region of the brainstem includes neural pathways and tracts that conduct signals from the brain down to the cerebellum and medulla, and tracts that carry the sensory signals up into the thalamus.Saladin Kenneth S.(2007) Anatomy & physiology the unity of form and function. Dubuque, IA: McGraw-Hill Structure The pons is in the brainstem situated between the midbrain and the medulla oblongata, and in front of the cerebellum. A separating groove between the pons and the medulla is the inferior pontine sulcus. The superior pontine sulcus separates the pons from the midbrain. The pons can be broadly divided into two parts: the basilar part of the pons (ventral ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Superior Olivary Complex
The superior olivary complex (SOC) or superior olive is a collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system. The SOC is intimately related to the trapezoid body: most of the cell groups of the SOC are dorsal (posterior in primates) to this axon bundle while a number of cell groups are embedded in the trapezoid body. Overall, the SOC displays a significant interspecies variation, being largest in bats and rodents and smaller in primates. Physiology The superior olivary nucleus plays a number of roles in hearing. The medial superior olive (MSO) is a specialized nucleus that is believed to measure the time difference of arrival of sounds between the ears (the interaural time difference or ITD). The ITD is a major cue for determining the azimuth of sounds, i.e., localising them on the azimuthal plane – their degree to the left or the right. The lateral ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tectorial Membrane
The tectoria membrane (TM) is one of two acellular membranes in the cochlea of the inner ear, the other being the basilar membrane (BM). "Tectorial" in anatomy means forming a cover. The TM is located above the spiral limbus and the spiral organ of Corti and extends along the longitudinal length of the cochlea parallel to the BM. Radially the TM is divided into three zones, the limbal, middle and marginal zones. Of these the limbal zone is the thinnest (transversally) and overlies the auditory teeth of Huschke with its inside edge attached to the spiral limbus. The marginal zone is the thickest (transversally) and is divided from the middle zone by Hensen's Stripe. It overlies the sensory inner hair cells and electrically-motile outer hair cells of the organ of Corti and during acoustic stimulation stimulates the inner hair cells through fluid coupling, and the outer hair cells via direct connection to their tallest stereocilia. Structure The TM is a gel-like structure containing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nerve Fiber
An axon (from Greek ἄξων ''áxōn'', axis), or nerve fiber (or nerve fibre: see spelling differences), is a long, slender projection of a nerve cell, or neuron, in vertebrates, that typically conducts electrical impulses known as action potentials away from the nerve cell body. The function of the axon is to transmit information to different neurons, muscles, and glands. In certain sensory neurons (pseudounipolar neurons), such as those for touch and warmth, the axons are called afferent nerve fibers and the electrical impulse travels along these from the periphery to the cell body and from the cell body to the spinal cord along another branch of the same axon. Axon dysfunction can be the cause of many inherited and acquired neurological disorders that affect both the peripheral and central neurons. Nerve fibers are classed into three typesgroup A nerve fibers, group B nerve fibers, and group C nerve fibers. Groups A and B are myelinated, and group C are unmyelinated. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spiral Ganglion
The spiral (cochlear) ganglion is a group of neuron cell bodies in the modiolus, the conical central axis of the cochlea. These bipolar neurons innervate the hair cells of the organ of Corti. They project their axons to the ventral and dorsal cochlear nuclei as the cochlear nerve, a branch of the vestibulocochlear nerve (CN VIII). Structure Neurons whose cell bodies lie in the spiral ganglion are strung along the bony core of the cochlea, and send fibers (axons) into the central nervous system (CNS). These bipolar neurons are the first neurons in the auditory system to fire an action potential, and supply all of the brain's auditory input. Their dendrites make synaptic contact with the base of hair cells, and their axons are bundled together to form the auditory portion of eighth cranial nerve. The number of neurons in the spiral ganglion is estimated to be about 35,000–50,000. Two apparent subtypes of spiral ganglion cells exist. Type I spiral ganglion cells comprise the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amplitudes
The amplitude of a periodic variable is a measure of its change in a single period (such as time or spatial period). The amplitude of a non-periodic signal is its magnitude compared with a reference value. There are various definitions of amplitude (see below), which are all functions of the magnitude of the differences between the variable's extreme values. In older texts, the phase of a periodic function is sometimes called the amplitude. Definitions Peak amplitude & semi-amplitude For symmetric periodic waves, like sine waves, square waves or triangle waves ''peak amplitude'' and ''semi amplitude'' are the same. Peak amplitude In audio system measurements, telecommunications and others where the measurand is a signal that swings above and below a reference value but is not sinusoidal, peak amplitude is often used. If the reference is zero, this is the maximum absolute value of the signal; if the reference is a mean value (DC component), the peak amplitude is the maximum ab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hair Cells
Hair cells are the sensory receptors of both the auditory system and the vestibular system in the ears of all vertebrates, and in the lateral line organ of fishes. Through mechanotransduction, hair cells detect movement in their environment. In mammals, the auditory hair cells are located within the spiral organ of Corti on the thin basilar membrane in the cochlea of the inner ear. They derive their name from the tufts of stereocilia called ''hair bundles'' that protrude from the apical surface of the cell into the fluid-filled cochlear duct. The stereocilia number from 50-100 in each cell while being tightly packed together and decrease in size the further away they are located from the kinocilium. The hair bundles are arranged as stiff columns that move at their base in response to stimuli applied to the tips. Mammalian cochlear hair cells are of two anatomically and functionally distinct types, known as outer, and inner hair cells. Damage to these hair cells results in d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basilar Membrane
The basilar membrane is a stiff structural element within the cochlea of the inner ear which separates two liquid-filled tubes that run along the coil of the cochlea, the scala media and the scala tympani. The basilar membrane moves up and down in response to incoming sound waves, which are converted to traveling waves on the basilar membrane. Structure The basilar membrane is a pseudo-resonant structure that, like the strings on an instrument, varies in width and stiffness. But unlike the parallel strings of a guitar, the basilar membrane is not a discrete set of resonant structures, but a single structure with varying width, stiffness, mass, damping, and duct dimensions along its length. The motion of the basilar membrane is generally described as a traveling wave. The properties of the membrane at a given point along its length determine its characteristic frequency (CF), the frequency at which it is most sensitive to sound vibrations. The basilar membrane is widest (0.42– ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
