Blindsight
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Blindsight
Blindsight is the ability of people who are cortically blind to respond to visual stimuli that they do not consciously see due to lesions in the primary visual cortex, also known as the striate cortex or Brodmann Area 17. The term was coined by Lawrence Weiskrantz and his colleagues in a paper published in a 1974 issue of ''Brain''. A previous paper studying the discriminatory capacity of a cortically blind patient was published in ''Nature'' in 1973. Type classification The majority of studies on blindsight are conducted on patients who are hemianopic, i.e. blind in one half of their visual field. Following the destruction of the left or right striate cortex, patients are asked to detect, localize, and discriminate amongst visual stimuli that are presented to their blind side, often in a forced-response or guessing situation, even though they may not consciously recognize the visual stimulus. Research shows that such blind patients may achieve a higher accuracy than would be e ...
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Lawrence Weiskrantz
Lawrence Weiskrantz (28 March 1926 – 27 January 2018) was a British neuropsychologist. Weiskrantz is credited with discovering the phenomenon of blindsight, and with establishing the role of the amygdala in emotional learning and emotional behavior. Blindsight is when a person with a brain injury causing blindness can nevertheless detect, point accurately at, and discriminate visually presented objects. Early life Weiskrantz originally attended Girard College, a boarding school in Philadelphia, due in part to the death of his father when he was six. After graduating, he attended Swarthmore College and served in World War II. Shortly before his graduation, he was awarded a Catherwood fellowship at Oxford University. Career Weiskrantz became Professor of Psychology at Oxford University where he remained a full professor until retirement in 1993. He then became an emeritus professor of the university and an emeritus fellow of Magdalen College. Weiskrantz had a lifelong i ...
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Anton Syndrome
Anton syndrome, also known as Anton's blindness and visual anosognosia, is a rare symptom of brain damage occurring in the occipital lobe. Those who have it are cortically blind, but affirm, often quite adamantly and in the face of clear evidence of their blindness, that they are capable of seeing. Failing to accept being blind, people with Anton syndrome dismiss evidence of their condition and employ confabulation to fill in the missing sensory input. It is named after the neurologist Gabriel Anton. Only 28 cases have been published. Although sometimes the two terms are used as synonymous, Anton syndrome must not be confused with Anton–Babinski syndrome which is characterised clinically by contralateral sensory neglect, anosognosia with associated affective indifference toward the condition (anosodiaphoria), construction and dressing apraxia. Anton–Babinski syndrome is the right-hemisphere equivalent of Gerstmann syndrome and it is due to non-dominant inferior parietal lob ...
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Pulvinar Nuclei
The pulvinar nuclei or nuclei of the pulvinar (nuclei pulvinares) are the nuclei (cell bodies of neurons) located in the thalamus (a part of the vertebrate brain). As a group they make up the collection called the pulvinar of the thalamus (pulvinar thalami), usually just called the pulvinar. The pulvinar is usually grouped as one of the ''lateral thalamic nuclei'' in rodents and carnivores, and stands as an independent complex in primates. Structure By convention, the pulvinar is divided into four nuclei: Their connectomic details are as follows: * The ''lateral'' and ''inferior'' pulvinar nuclei have widespread connections with early visual cortical areas. * The dorsal part of the ''lateral'' pulvinar nucleus predominantly has connections with posterior parietal cortex and the dorsal stream cortical areas. * The ''medial'' pulvinar nucleus has widespread connections with cingulate, posterior parietal, premotor and prefrontal cortical areas. * The pulvinar also has input fr ...
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Cortical Blindness
Cortical blindness is the total or partial loss of vision in a normal-appearing eye caused by damage to the brain's occipital cortex. Cortical blindness can be acquired or congenital, and may also be transient in certain instances. Acquired cortical blindness is most often caused by loss of blood flow to the occipital cortex from either unilateral or bilateral posterior cerebral artery blockage (ischemic stroke) and by cardiac surgery. In most cases, the complete loss of vision is not permanent and the patient may recover some of their vision (cortical visual impairment). Congenital cortical blindness is most often caused by perinatal ischemic stroke, encephalitis, and meningitis. Rarely, a patient with acquired cortical blindness may have little or no insight that they have lost vision, a phenomenon known as Anton–Babinski syndrome. Cortical blindness and cortical visual impairment (CVI), which refers to the partial loss of vision caused by cortical damage, are both classified a ...
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Lateral Geniculate Nucleus
In neuroanatomy, the lateral geniculate nucleus (LGN; also called the lateral geniculate body or lateral geniculate complex) is a structure in the thalamus and a key component of the mammalian visual pathway. It is a small, ovoid, ventral projection of the thalamus where the thalamus connects with the optic nerve. There are two LGNs, one on the left and another on the right side of the thalamus. In humans, both LGNs have six layers of neurons (grey matter) alternating with optic fibers (white matter). The LGN receives information directly from the ascending retinal ganglion cells via the optic tract and from the reticular activating system. Neurons of the LGN send their axons through the optic radiation, a direct pathway to the primary visual cortex. In addition, the LGN receives many strong feedback connections from the primary visual cortex. In humans as well as other mammals, the two strongest pathways linking the eye to the brain are those projecting to the dorsal part of th ...
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Riddoch Syndrome
The Riddoch syndrome is a term coined by Zeki and Ffytche (1998) in a paper published in ''Brain''. The term acknowledges the work of George Riddoch who was the first to describe a condition in which a form of visual impairment, caused by lesion A lesion is any damage or abnormal change in the tissue of an organism, usually caused by disease or trauma. ''Lesion'' is derived from the Latin "injury". Lesions may occur in plants as well as animals. Types There is no designated classifi ...s in the occipital lobe, leaves the sufferer blind but able to distinguish visual stimuli with specific characteristics when these appear in the patient's blind field. The most common stimuli that can be perceived ''consciously'' are the presence and direction of fast moving objects (moving at a speed in excess of 10 degrees per second); in his work these moving objects were described as "vague and shadowy". Riddoch concluded from his observations that "movement may be recognized as a specia ...
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Lateral Geniculate Nucleus
In neuroanatomy, the lateral geniculate nucleus (LGN; also called the lateral geniculate body or lateral geniculate complex) is a structure in the thalamus and a key component of the mammalian visual pathway. It is a small, ovoid, ventral projection of the thalamus where the thalamus connects with the optic nerve. There are two LGNs, one on the left and another on the right side of the thalamus. In humans, both LGNs have six layers of neurons (grey matter) alternating with optic fibers (white matter). The LGN receives information directly from the ascending retinal ganglion cells via the optic tract and from the reticular activating system. Neurons of the LGN send their axons through the optic radiation, a direct pathway to the primary visual cortex. In addition, the LGN receives many strong feedback connections from the primary visual cortex. In humans as well as other mammals, the two strongest pathways linking the eye to the brain are those projecting to the dorsal part of th ...
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Lens (anatomy)
The lens, or crystalline lens, is a transparent biconvex structure in the eye that, along with the cornea, helps to refract light to be focused on the retina. By changing shape, it functions to change the focal length of the eye so that it can focus on objects at various distances, thus allowing a sharp real image of the object of interest to be formed on the retina. This adjustment of the lens is known as '' accommodation'' (see also below). Accommodation is similar to the focusing of a photographic camera via movement of its lenses. The lens is flatter on its anterior side than on its posterior side. In humans, the refractive power of the lens in its natural environment is approximately 18 dioptres, roughly one-third of the eye's total power. Structure The lens is part of the anterior segment of the human eye. In front of the lens is the iris, which regulates the amount of light entering into the eye. The lens is suspended in place by the suspensory ligament of the lens ...
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Cerebral Cortex
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system. It plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The cerebral cortex is part of the brain responsible for cognition. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the cranium. Apart from minimising brain and cranial volume, cortical folding is crucial for the brain ...
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Eyes
Eyes are organs of the visual system. They provide living organisms with vision, the ability to receive and process visual detail, as well as enabling several photo response functions that are independent of vision. Eyes detect light and convert it into electro-chemical impulses in neurons (neurones). In higher organisms, the eye is a complex optical system which collects light from the surrounding environment, regulates its intensity through a diaphragm, focuses it through an adjustable assembly of lenses to form an image, converts this image into a set of electrical signals, and transmits these signals to the brain through complex neural pathways that connect the eye via the optic nerve to the visual cortex and other areas of the brain. Eyes with resolving power have come in ten fundamentally different forms, and 96% of animal species possess a complex optical system. Image-resolving eyes are present in molluscs, chordates and arthropods. The most simple eyes, pit eyes, ar ...
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Stereoscopic Acuity
Stereoscopic acuity, also stereoacuity, is the smallest detectable depth difference that can be seen in binocular vision. Specification and measurement Stereoacuity is most simply explained by considering one of its earliest test, a two-peg device, named Howard-Dolman test after its inventors: The observer is shown a black peg at a distance of 6m (=20 feet). A second peg, below it, can be moved back and forth until it is just detectably nearer than the fixed one. Stereoacuity is defined as the minimum angle detectable, calculated as the difference between the angles subtended by both positions, A and B. Stereoacuity is possible due to binocular disparity, i.e., the difference in their binocular parallax. Taking into account that a small angle expressed in radians can be approximated by its tangent, the formula to calculate stereoacuity ''dγ'' is this: :d\gamma = c\,a\,dz/(z\,(z - dz)) where ''a'' is the interocular separation of the observer, ''z'' the distance of the fixed peg ...
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Superior Colliculus
In neuroanatomy, the superior colliculus () is a structure lying on the roof of the mammalian midbrain. In non-mammalian vertebrates, the homologous structure is known as the optic tectum, or optic lobe. The adjective form ''tectal'' is commonly used for both structures. In mammals, the superior colliculus forms a major component of the midbrain. It is a paired structure and together with the paired inferior colliculi forms the corpora quadrigemina. The superior colliculus is a layered structure, with a pattern that is similar to all mammals. The layers can be grouped into the superficial layers ( stratum opticum and above) and the deeper remaining layers. Neurons in the superficial layers receive direct input from the retina and respond almost exclusively to visual stimuli. Many neurons in the deeper layers also respond to other modalities, and some respond to stimuli in multiple modalities. The deeper layers also contain a population of motor-related neurons, capable of activat ...
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