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Benchtop Nuclear Magnetic Resonance Spectrometer
A Benchtop nuclear magnetic resonance spectrometer (Benchtop NMR spectrometer) refers to a Fourier transform nuclear magnetic resonance (FT-NMR) spectrometer that is significantly more compact and portable than the conventional equivalents, such that it is portable and can reside on a laboratory benchtop. This convenience comes from using permanent magnets, which have a lower magnetic field and decreased sensitivity compared to the much larger and more expensive cryogen cooled superconducting NMR magnets. Instead of requiring dedicated infrastructure, rooms and extensive installations these benchtop instruments can be placed directly on the bench in a lab and moved as necessary (''e.g.,'' to the fumehood). These spectrometers offer improved workflow, even for novice users, as they are simpler and easy to use. They differ from relaxometers in that they can be used to measure high resolution NMR spectra and are not limited to the determination of relaxation or diffusion parameters ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fourier Transform
A Fourier transform (FT) is a mathematical transform that decomposes functions into frequency components, which are represented by the output of the transform as a function of frequency. Most commonly functions of time or space are transformed, which will output a function depending on temporal frequency or spatial frequency respectively. That process is also called ''analysis''. An example application would be decomposing the waveform of a musical chord into terms of the intensity of its constituent pitches. The term ''Fourier transform'' refers to both the frequency domain representation and the mathematical operation that associates the frequency domain representation to a function of space or time. The Fourier transform of a function is a complex-valued function representing the complex sinusoids that comprise the original function. For each frequency, the magnitude ( absolute value) of the complex value represents the amplitude of a constituent complex sinusoid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uninterruptible Power Supply
An uninterruptible power supply or uninterruptible power source (UPS) is an electrical apparatus that provides emergency power to a load when the input power source or mains power fails. A UPS differs from an auxiliary or emergency power system or standby generator in that it will provide near-instantaneous protection from input power interruptions, by supplying energy stored in batteries, supercapacitors, or flywheels. The on-battery run-time of most uninterruptible power sources is relatively short (only a few minutes) but sufficient to start a standby power source or properly shut down the protected equipment. It is a type of continual power system. A UPS is typically used to protect hardware such as computers, data centers, telecommunication equipment or other electrical equipment where an unexpected power disruption could cause injuries, fatalities, serious business disruption or data loss. UPS units range in size from ones designed to protect a single computer without ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxford Instruments
Oxford Instruments plc is a United Kingdom manufacturing and research company that designs and manufactures tools and systems for industry and research. The company is headquartered in Abingdon, Oxfordshire, England, with sites in the United Kingdom, United States, Europe, and Asia. It is listed on the London Stock Exchange and is a constituent of the FTSE 250 Index. History The company was founded by Sir Martin Wood in 1959, at his home in Northmoor Road, North Oxford, with help from his wife Audrey Wood (Lady Wood) to manufacture superconducting magnets for use in scientific research, starting in his garden shed in Northmoor Road, Oxford, England. It was the first substantial commercial spin-out company from the University of Oxford and was first listed on the London Stock Exchange in 1983. It had a pioneering role in the development of magnetic resonance imaging, providing the first superconducting magnets for this application. The first commercial MRI whole body sca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nanalysis
Nanalysis Scientific Corp. is a scientific instrument manufacturer based in Calgary, AB, Canada. Established in 2009, Nanalysis specializes in the production of compact Nuclear Magnetic Resonance (NMR) spectroscopic instrumentation. As a new public company it is trading on the TSX Venture Exchange (TSXV) under the ticker symbol NSCI since June 2019, and later on the Frankfurt Stock Exchange (FRA) under the ticker symbol 1N1. The first product introduced by Nanalysis in 2013 was the 60 MHz NMReady benchtop NMR spectrometer A Benchtop nuclear magnetic resonance spectrometer (Benchtop NMR spectrometer) refers to a Fourier transform Nuclear magnetic resonance spectroscopy, nuclear magnetic resonance (FT-NMR) spectrometer that is significantly more compact and portable t ..., capable of observing multinuclear 1D and 2D NMR spectra. The Nanalysis 60 MHz was the first portable, high-resolution 60 MHz benchtop NMR spectrometer released on the market. Notable for their ease ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Capillary
A capillary is a small blood vessel from 5 to 10 micrometres (μm) in diameter. Capillaries are composed of only the tunica intima, consisting of a thin wall of simple squamous endothelial cells. They are the smallest blood vessels in the body: they convey blood between the arterioles and venules. These microvessels are the site of exchange of many substances with the interstitial fluid surrounding them. Substances which cross capillaries include water, oxygen, carbon dioxide, urea, glucose, uric acid, lactic acid and creatinine. Lymph capillaries connect with larger lymph vessels to drain lymphatic fluid collected in the microcirculation. During early embryonic development, new capillaries are formed through vasculogenesis, the process of blood vessel formation that occurs through a '' de novo'' production of endothelial cells that then form vascular tubes. The term '' angiogenesis'' denotes the formation of new capillaries from pre-existing blood vessels and already ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thermo Scientific
Thermo Fisher Scientific Inc. is an American supplier of scientific instrumentation, reagents and consumables, and software services. Based in Waltham, Massachusetts, Thermo Fisher was formed through the merger of Thermo Electron and Fisher Scientific in 2006. Thermo Fisher Scientific has acquired other reagent, consumable, instrumentation, and service providers, including: Life Technologies Corporation (2013), Alfa Aesar (2015), Affymetrix (2016), FEI Company (2016), BD Advanced Bioprocessing (2018), and PPD (2021). As of 2017, the company had a market capitalization of $21 billion and was a Fortune 500 company. Annual revenue in 2021 was US$39.21 billion. In March 2020, Thermo Fisher Scientific received emergency use authorization from the FDA for a test for SARS-CoV-2 to help mitigate the COVID-19 pandemic. History Predecessors and merger Thermo Electron was co-founded in 1956 by George N. Hatsopoulos and Peter M Nomikos. Hatsopoulos received a PhD from MIT in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NMR Tube
An NMR tube is a thin glass walled tube used to contain samples in nuclear magnetic resonance spectroscopy. Typically NMR tubes come in 5 mm diameters but 10 mm and 3 mm samples are known. It is important that the tubes are uniformly thick and well-balanced to ensure that NMR tube spins at a regular rate (i.e., they do not wobble), usually about 20 Hz in the NMR spectrometer. Construction NMR tubes are typically made of borosilicate glass. They are available in seven and eight inch lengths; a 5 mm tube outer diameter is most common, but 3 mm and 10 mm outer diameters are available as well. Where boron NMR is desired, quartz NMR tubes containing low concentrations of boron (as opposed to borosilicate glass) are available. Specialized closures such as J. Young valves and screwcap closures are available aside from more common polyethylene caps. Two common specifications for NMR tubes are concentricity and camber. Concentricity refers to the variatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deuterated Chloroform
Deuterated chloroform, also known as chloroform-''d'', is the organic compound with the formula C2HCl3 or . Deuterated chloroform is a common solvent used in NMR spectroscopy. The properties of are virtually identical. Preparation Deuterated chloroform is commercially available. It is more easily produced and less expensive than deuterated dichloromethane. Deuterochloroform is produced by the reaction of hexachloroacetone with deuterium oxide, using pyridine as a catalyst. The large difference in boiling points between the starting material and product facilitate purification by distillation. : NMR solvent In proton NMR spectroscopy, deuterated solvent (enriched to >99% deuterium) is typically used to avoid recording a large interfering signal or signals from the proton(s) (i.e., hydrogen-1) present in the solvent itself. If nondeuterated chloroform (containing a full equivalent of protium) were used as solvent, the solvent signal would almost certainly overwhelm and obscure a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Two-dimensional Nuclear Magnetic Resonance Spectroscopy
Two-dimensional nuclear magnetic resonance spectroscopy (2D NMR) is a set of nuclear magnetic resonance spectroscopy (NMR) methods which give data plotted in a space defined by two frequency axes rather than one. Types of 2D NMR include correlation spectroscopy (COSY), J-spectroscopy, exchange spectroscopy (EXSY), and nuclear Overhauser effect spectroscopy (NOESY). Two-dimensional NMR spectra provide more information about a molecule than one-dimensional NMR spectra and are especially useful in determining the structure of a molecule, particularly for molecules that are too complicated to work with using one-dimensional NMR. The first two-dimensional experiment, COSY, was proposed by Jean Jeener, a professor at the Université Libre de Bruxelles, in 1971. This experiment was later implemented by Walter P. Aue, Enrico Bartholdi and Richard R. Ernst, who published their work in 1976. Fundamental concepts Each experiment consists of a sequence of radio frequency (RF) pulses with d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Magritek
Magritek is a scientific instrument company based in Wellington, New Zealand, and Aachen, Germany, that was established in 2004 and specialises in compact, portable and benchtop nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) products. The technology was originally developed to enable NMR measurements in Antarctica by scientists at Massey and Victoria Universities in New Zealand, including Dr Robin Dykstra. This was combined with compact, handheld NMR magnet technology developed by researchers at RWTH University in Aachen. Magritek is well known in New Zealand as an example of successful commercialisation of university developed IP and in 2010 the team behind the company won the Prime Minister's Science Prize led by famous New Zealand scientist Sir Paul Callaghan. Magritek uses novel magnetic resonance techniques such as Earth's field NMR and Halbach array permanent magnets to create products such as the Spinsolve benchtop NMR spectrometer A Benchtop nuclea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neodymium Magnet
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Nuclear Magnetic Resonance Spectroscopy
Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique to observe local magnetic fields around atomic nuclei. The sample is placed in a magnetic field and the NMR signal is produced by excitation of the nuclei sample with radio waves into nuclear magnetic resonance, which is detected with sensitive radio receivers. The intramolecular magnetic field around an atom in a molecule changes the resonance frequency, thus giving access to details of the electronic structure of a molecule and its individual functional groups. As the fields are unique or highly characteristic to individual compounds, in modern organic chemistry practice, NMR spectroscopy is the definitive method to identify monomolecular organic compounds. The principle of NMR usually involves three sequential steps: # The alignment (polarization) of the magnetic nuclear spins in an applied, constant magnetic field B0. # The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
