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Benzoylurea
Benzoylureas are chemical derivatives of ''N''-benzoyl-''N′''-phenylurea (benzoylurea). They are best known for their use as insecticides. They act as insect growth regulators by inhibiting synthesis of chitin in the insect's body. One of the more commonly used benzoylurea pesticides is diflubenzuron. Others include chlorfluazuron, flufenoxuron, hexaflumuron, and triflumuron. Lufenuron is the active compound in flea control medication for pet dogs and cats. 3-(Iodoacetamido)-benzoylurea (3-IAABU) is one of several benzoylurea compounds which have been investigated as potential anticancer agents. Environmental toxicity When applied in a dispersed way, for example through fumigation or spraying, these chemicals have an effect against a wide range of insect species, some of which may be beneficial to human activities, including crop-pollinators such as bees. In addition, as with many insecticides, application may result in the killing of natural predators or controls a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Insect Growth Regulator
An insect growth regulator (IGR) is a substance (chemical) that inhibits the life cycle of an insect. IGRs are typically used as insecticides to control populations of harmful insect pests such as cockroaches and fleas. Advantages Many IGRs are labeled "reduced risk" by the Environmental Protection Agency, meaning that they target juvenile harmful insect populations while causing less detrimental effects to beneficial insects. Many beekeepers have reported IGR's negatively affecting brood and young bees. Unlike classic insecticides, IGRs do not affect an insect's nervous system and are thus more friendly to "worker insects" within closed environments. IGRs are also more compatible with pest management systems that use biological controls. In addition, while insects can become resistant to insecticides, they are less likely to become resistant to IGRs. Mechanism of action As an insect grows it molts, growing a new exoskeleton under its old one and then shedding the old one to al ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diflubenzuron
Diflubenzuron is an insecticide of the benzoylurea class. It is used in forest management and on field crops to selectively control insect pests, particularly forest tent caterpillar moths, boll weevils, gypsy moths, and other types of moths. It is a widely used larvicide in India for control of mosquito larvae by public health authorities. Diflubenzuron is approved by the WHO Pesticide Evaluation Scheme. Mechanism of action The mechanism of action of diflubenzuron involves inhibiting the production of chitin which is used by an insect to build its exoskeleton. It triggers insect larvae to molt early without a properly formed exoskeleton, resulting in the death of the larvae. Environmental toxicity Diflubenzuron has been evaluated by the United States Environmental Protection Agency (EPA), and it is classified as non-carcinogenic. 4-Chloroaniline, a metabolite of diflubenzuron which has been classified as a carcinogen, is produced after diflubenzuron has been ingested. The s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lufenuron
Lufenuron is the active ingredient in the Veterinary medicine, veterinary flea control medication Program, and one of the two active ingredients in the flea, heartworm, ringworm and anthelmintic medicine milbemycin oxime/lufenuron (Sentinel). Lufenuron is stored in the animal's body fat and transferred to adult fleas through the host's blood when they feed. Adult fleas transfer it to their growing eggs through their blood, and to hatched larvae feeding on their excrement. It does not kill adult fleas. Lufenuron, a benzoylurea pesticide, inhibits the production of chitin in insects. Without chitin, a larval flea will never develop a hard outer shell (exoskeleton). With its inner organs exposed to air, the insect dies from dehydration soon after hatching or molting (shedding its old, smaller shell). Lufenuron is also used to fight fungus, fungal infections, since fungus cell walls are about one third chitin. Lufenuron is also sold as an agricultural pesticide for use against lepi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-Benzoyl-N'-phenylurea
''N''-Benzoyl-''N''′-phenylurea is an organic compound with Ph CO NH CO NH Ph formula. It is benzoylurea derivative substituted with phenyl group on the opposite nitrogen atom. Structure and bonding Structure of ''N''-benzoyl-''N''′-phenylurea was first determined in 2010. Molecules in this compound are approximately flat and exhibit high charge delocalization. Within the molecule an intramolecular N−H⋅⋅⋅O hydrogen bond is present forming pseudoaromatic 6-membered ring. Additionally intermolecular N−H⋅⋅⋅O hydrogen bonds are also present combining two molecules into a centrosymmetric dimer (8-membered ring is formed). Carbonyl C=O bond distances are equal to ca. 1.23 Å, C−N distances are in range of 1.34 to 1.41 Å. Synthesis In 1965 ''N''-benzoyl-''N''′-phenylurea was synthesized when dry ''N''-chlorobenzamide was reacted with phenylisocyanate or refluxed in dry benzene with anhydrous potassium fluoride Potassium fluoride is the chemical compo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flufenoxuron
Flufenoxuron is an insecticide that belongs to the benzoylurea chitin synthesis inhibitor group, which also includes diflubenzuron, triflumuron, and lufenuron. Flufenoxuron is a white crystalline powder. It is insoluble in water, is not flammable, and is not an oxidizer. Toxicology and safety Flufenoxuron toxicity to humans and other mammals is low, but it has a very high bioaccumulation in fish Fish are aquatic, craniate, gill-bearing animals that lack limbs with digits. Included in this definition are the living hagfish, lampreys, and cartilaginous and bony fish as well as various extinct related groups. Approximately 95% of .... References {{Organic-compound-stub Insecticides ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diflubenzuron
Diflubenzuron is an insecticide of the benzoylurea class. It is used in forest management and on field crops to selectively control insect pests, particularly forest tent caterpillar moths, boll weevils, gypsy moths, and other types of moths. It is a widely used larvicide in India for control of mosquito larvae by public health authorities. Diflubenzuron is approved by the WHO Pesticide Evaluation Scheme. Mechanism of action The mechanism of action of diflubenzuron involves inhibiting the production of chitin which is used by an insect to build its exoskeleton. It triggers insect larvae to molt early without a properly formed exoskeleton, resulting in the death of the larvae. Environmental toxicity Diflubenzuron has been evaluated by the United States Environmental Protection Agency (EPA), and it is classified as non-carcinogenic. 4-Chloroaniline, a metabolite of diflubenzuron which has been classified as a carcinogen, is produced after diflubenzuron has been ingested. The s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flufenoxuron
Flufenoxuron is an insecticide that belongs to the benzoylurea chitin synthesis inhibitor group, which also includes diflubenzuron, triflumuron, and lufenuron. Flufenoxuron is a white crystalline powder. It is insoluble in water, is not flammable, and is not an oxidizer. Toxicology and safety Flufenoxuron toxicity to humans and other mammals is low, but it has a very high bioaccumulation in fish Fish are aquatic, craniate, gill-bearing animals that lack limbs with digits. Included in this definition are the living hagfish, lampreys, and cartilaginous and bony fish as well as various extinct related groups. Approximately 95% of .... References {{Organic-compound-stub Insecticides ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Triflumuron
Triflumuron is the active ingredient in some IGRs ( insect growth regulators). An aromatic ether In organic chemistry, ethers are a class of compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. They have the general formula , where R and R′ represent the alkyl or aryl groups. Ethers can again be ..., organofluorine compound from the benzoylurea class and member of monochlorobenzenes. References {{Reflist Insecticides Ureas Trifluoromethyl ethers ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioaccumulation
Bioaccumulation is the gradual accumulation of substances, such as pesticides or other chemicals, in an organism. Bioaccumulation occurs when an organism absorbs a substance at a rate faster than that at which the substance is lost or eliminated by catabolism and excretion. Thus, the longer the biological half-life of a toxic substance, the greater the risk of chronic poisoning, even if environmental levels of the toxin are not very high. Bioaccumulation, for example in fish, can be predicted by models. Hypothesis for molecular size cutoff criteria for use as bioaccumulation potential indicators are not supported by data. Biotransformation can strongly modify bioaccumulation of chemicals in an organism. Toxicity induced by metals is associated with bioaccumulation and biomagnification. Storage or uptake of metals faster than the rate at which an organism metabolizes and excretes lead to the accumulation of that metal. The presence of various chemicals and harmful substances in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Environmental Impact Of Pesticides
The environmental effects of pesticides describe the broad series of consequences of using pesticides. The unintended consequences of pesticides is one of the main drivers of the negative impact of modern industrial agriculture on the environment. Pesticides, because they are toxic chemicals meant to kill pest species, can affect non-target species, such as plants, animals and humans. Over 98% of sprayed insecticides and 95% of herbicides reach a destination other than their target species, because they are sprayed or spread across entire agricultural fields. Other agrochemicals, such as fertilizers, can also have negative effects on the environment. The negative effects of pesticides are not just in the area of application. Runoff and pesticide drift can carry pesticides into distant aquatic environments or other fields, grazing areas, human settlements and undeveloped areas. Other problems emerge from poor production, transport, storage and disposal practices.Tashkent (1998)Pa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs) or it may aim to prolong life or to reduce symptoms ( palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called ''medical oncology''. The term ''chemotherapy'' has come to connote non-specific usage of intracellular poisons to inhibit mitosis (cell division) or induce DNA damage, which is why inhibition of DNA repair can augment chemotherapy. The connotation of the word chemotherapy excludes more selective agents that block extracellular signals (signal transduction). The development of therapies with specific molecular or genetic targets, wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
