Benzoyl-CoA 2,3-dioxygenase
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Benzoyl-CoA 2,3-dioxygenase
Benzoyl-CoA 2,3-dioxygenase (, ''benzoyl-CoA dioxygenase/reductase'', ''BoxBA'', ''BoxA/BoxB system'') is an enzyme with systematic name ''benzoyl-CoA,NADPH:oxygen oxidoreductase (2,3-hydroxylating)''. This enzyme catalyses the following chemical reaction : benzoyl-CoA + NADPH + H+ + O2 \rightleftharpoons 2,3-dihydro-2,3-dihydroxybenzoyl-CoA + NADP+ Benzoyl-CoA 2,3-dioxygenase is involved in aerobic benzoate metabolism in ''Azoarcus evansii ''Azoarcus evansii'' is a species of bacteria. Its type strain is KB 740T. This particular strain of ''Azoarcus evansii'' has been identified in substantial numbers in the human digestive system. Research has indicated that it is perhaps one of ...''. References External links * {{Portal bar, Biology, border=no EC 1.14.12 ...
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Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction ra ...
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List Of Enzymes
This article lists enzymes by their classification in the International Union of Biochemistry and Molecular Biology's Enzyme Commission (EC) numbering system. * List of EC numbers (EC 5) * List of EC numbers (EC 6) :Oxidoreductases (EC 1) (Oxidoreductase) *Dehydrogenase * Luciferase *DMSO reductase :EC 1.1 (act on the CH-OH group of donors) * :EC 1.1.1 (with NAD+ or NADP+ as acceptor) ** Alcohol dehydrogenase (NAD) ** Alcohol dehydrogenase (NADP) **Homoserine dehydrogenase ** Aminopropanol oxidoreductase **Diacetyl reductase **Glycerol dehydrogenase **Propanediol-phosphate dehydrogenase ** glycerol-3-phosphate dehydrogenase (NAD+) ** D-xylulose reductase **L-xylulose reductase **Lactate dehydrogenase **Malate dehydrogenase **Isocitrate dehydrogenase ** HMG-CoA reductase * :EC 1.1.2 (with a cytochrome as acceptor) * :EC 1.1.3 (with oxygen as acceptor) **Glucose oxidase **L-gulonolactone oxidase **Thiamine oxidase **Xanthine oxidase * :EC 1.1.4 (with a disul ...
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Catalysis
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quickly, very small amounts of catalyst often suffice; mixing, surface area, and temperature are important factors in reaction rate. Catalysts generally react with one or more reactants to form intermediates that subsequently give the final reaction product, in the process of regenerating the catalyst. Catalysis may be classified as either homogeneous, whose components are dispersed in the same phase (usually gaseous or liquid) as the reactant, or heterogeneous, whose components are not in the same phase. Enzymes and other biocatalysts are often considered as a third category. Catalysis is ubiquitous in chemical industry of all kinds. Estimates are that 90% of all commercially produced chemical products involve catalysts at some s ...
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Chemical Reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and breaking of chemical bonds between atoms, with no change to the Atomic nucleus, nuclei (no change to the elements present), and can often be described by a chemical equation. Nuclear chemistry is a sub-discipline of chemistry that involves the chemical reactions of unstable and radioactive Chemical element, elements where both electronic and nuclear changes can occur. The substance (or substances) initially involved in a chemical reaction are called reagent, reactants or reagents. Chemical reactions are usually characterized by a chemical change, and they yield one or more Product (chemistry), products, which usually have properties different from the reactants. Reactions often consist of a sequence o ...
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Benzoyl-CoA
Benzoyl-CoA is a molecule implied in the activity of the different enzymes 4-hydroxybenzoyl-CoA reductase, benzoyl-CoA reductase, benzoyl-CoA 3-monooxygenase, benzoate-CoA ligase, 2alpha-hydroxytaxane 2-O-benzoyltransferase, anthranilate N-benzoyltransferase, biphenyl synthase, glycine N-benzoyltransferase, ornithine N-benzoyltransferase and phenylglyoxylate dehydrogenase (acylating). It is a substrate in the formation of xanthonoids in ''Hypericum androsaemum'' by benzophenone synthase, condensing a molecule of benzoyl-CoA with three malonyl-CoA, yielding to 2,4,6-trihydroxybenzophenone. This intermediate is subsequently converted by a benzophenone 3′-hydroxylase Benzophenone is the organic compound with the formula (C6H5)2CO, generally abbreviated Ph2CO. It is a white solid that is soluble in organic solvents. Benzophenone is a widely used building block in organic chemistry, being the parent diarylket ..., a cytochrome P450 monooxygenase, leading to the formation of ...
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Azoarcus Evansii
''Azoarcus evansii'' is a species of bacteria. Its type strain is KB 740T. This particular strain of ''Azoarcus evansii'' has been identified in substantial numbers in the human digestive system. Research has indicated that it is perhaps one of the most influential bacterium in maintaining a healthy body. One of the key functions identified in these studies is the ability to maintain and control ''Lactobacillus johnsonii ''Lactobacillus johnsonii'' is a species in the genus ''Lactobacillus'' identified in 1980 by John L. Johnson, an American microbiologist and his associates. Its type strain is ATCC 33200. It is part of the healthy vaginal microbiota and has bee ...'' populations in the gut. ''Lactobacillus johnsonii'', although useful at low population levels, can cause necrosis of the stomach if allowed to grow to uninhibited levels. The ''Azoarcus evansii'' consumes (literally eats) the ''Lactobacillus johnsonii'' to maintain a healthy population level. It has been demon ...
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