Bat Flight
Bats are the only mammal capable of true flight. Bats use flight for capturing prey, breeding, avoiding predators, and long-distance migration. Bat wing morphology is often highly specialized to the needs of the species. Evolution Charles Darwin foresaw an issue with his theory of evolution by natural selection in the evolution of complex traits such as eyes or "the structure and habits of a bat."Darwin, C. (1968). On the origin of species by means of natural selection. 1859. London: Murray Google Scholar. Indeed, the oldest bat fossils are very similar in wing morphology to the bats of today, despite living and dying 52.5 million years ago.Sears, K. E., Behringer, R. R., Rasweiler, J. J., & Niswander, L. A. (2006). Development of bat flight: morphologic and molecular evolution of bat wing digits. Proceedings of the National Academy of Sciences, 103(17), 6581-6586. '' Onychonycteris finneyi,'' the earliest known bat, already possessed powered flight. ''O. finneyi'' likely ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
PSM V52 D542 Evolution Of Limbs Into Wings
PSM, an acronym, may refer to: Organizations * Sepaktakraw Association of Malaysia ( ms, Persatuan Sepaktakraw Malaysia; PSM), a national governing body in Malaysia. * Pakistan School Muscat, a Pakistani co-educational institute in Oman * Palestine Solidarity Movement, a student organization in the United States * Panhellenic Socialist Movement, a centre-left party in Greece * Parti Sosialis Malaysia, a socialist political party in Malaysia * PlayStation: The Official Magazine, a magazine originally known as PlayStation Magazine or PSM * Ponce School of Medicine, a post-graduate medical school located in Ponce, Puerto Rico * Power Systems Mfg, a subsidiary of Alstom, specializing in aftermarket gas turbine servicing for power generating industry. * ''Poznańska Spółdzielnia Mieszkaniowa'', a housing cooperative administering most of the Piątkowo district of Poznań, Poland * PSM3, a UK video game magazine specializing in Sony consoles * PSM Makassar, a football club that pla ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Connective Tissue
Connective tissue is one of the four primary types of animal tissue, along with epithelial tissue, muscle tissue, and nervous tissue. It develops from the mesenchyme derived from the mesoderm the middle embryonic germ layer. Connective tissue is found in between other tissues everywhere in the body, including the nervous system. The three meninges, membranes that envelop the brain and spinal cord are composed of connective tissue. Most types of connective tissue consists of three main components: elastic and collagen fibers, ground substance, and cells. Blood, and lymph are classed as specialized fluid connective tissues that do not contain fiber. All are immersed in the body water. The cells of connective tissue include fibroblasts, adipocytes, macrophages, mast cells and leucocytes. The term "connective tissue" (in German, ''Bindegewebe'') was introduced in 1830 by Johannes Peter Müller. The tissue was already recognized as a distinct class in the 18th century. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Elastic Fiber
Elastic fibers (or yellow fibers) are an essential component of the extracellular matrix composed of bundles of proteins (elastin) which are produced by a number of different cell types including fibroblasts, endothelial, smooth muscle, and airway epithelial cells. These fibers are able to stretch many times their length, and snap back to their original length when relaxed without loss of energy. Elastic fibers include elastin, elaunin and oxytalan. Elastic tissue is classified as "connective tissue proper". Elastic fibers are formed via elastogenesis, a highly complex process involving several key proteins including fibulin-4, fibulin-5, latent transforming growth factor β binding protein 4, and microfibril associated protein 4. In this process tropoelastin, the soluble monomeric precursor to elastic fibers is produced by elastogenic cells and chaperoned to the cell surface. Following excretion from the cell, tropoelastin self associates into ~200 nm particles by coacer ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Patagium
The patagium (plural: patagia) is a membranous body part that assists an animal in obtaining lift when gliding or flight. The structure is found in extant and extinct groups of flying and gliding animals including bats, birds, some dromaeosaurs, pterosaurs, gliding mammals, some flying lizards, and flying frogs. The patagium that stretches between an animal's hind limbs is called the uropatagium (especially in bats) or the interfemoral membrane. Bats In bats, the skin forming the surface of the wing is an extension of the skin of the abdomen that runs to the tip of each digit, uniting the forelimb with the body. The patagium of a bat has four distinct parts: #Propatagium: the patagium present from the neck to the first digit. #Dactylopatagium: the portion found within the digits. #Plagiopatagium: the portion found between the last digit and the hindlimbs. #Uropatagium: the posterior portion of the flap between the two hindlimbs. Pterosaurs In the flying pterosaurs, the patag ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Flying Squirrel
Flying squirrels (scientifically known as Pteromyini or Petauristini) are a tribe of 50 species of squirrels in the family Sciuridae. Despite their name, they are not in fact capable of full flight in the same way as birds or bats, but they are able to glide from one tree to another with the aid of a patagium, a furred parachute-like skin membrane that stretches from wrist to ankle. Their long tails also provide stability as they glide. Anatomically they are very similar to other squirrels with a number of adaptations to suit their lifestyle; their limb bones are longer and their hand bones, foot bones, and distal vertebrae are shorter. Flying squirrels are able to steer and exert control over their glide path with their limbs and tail. Molecular studies have shown that flying squirrels are monophyletic and originated some 18–20 million years ago. The genus Paracitellus is the earliest lineage to the flying squirrel dating back to the late Oligocene era. Most are nocturnal ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Vertebrate
Vertebrates () comprise all animal taxa within the subphylum Vertebrata () ( chordates with backbones), including all mammals, birds, reptiles, amphibians, and fish. Vertebrates represent the overwhelming majority of the phylum Chordata, with currently about 69,963 species described. Vertebrates comprise such groups as the following: * jawless fish, which include hagfish and lampreys * jawed vertebrates, which include: ** cartilaginous fish (sharks, rays, and ratfish) ** bony vertebrates, which include: *** ray-fins (the majority of living bony fish) *** lobe-fins, which include: **** coelacanths and lungfish **** tetrapods (limbed vertebrates) Extant vertebrates range in size from the frog species ''Paedophryne amauensis'', at as little as , to the blue whale, at up to . Vertebrates make up less than five percent of all described animal species; the rest are invertebrates, which lack vertebral columns. The vertebrates traditionally include the hagfish, which do no ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Pectoralis Major
The pectoralis major () is a thick, fan-shaped or triangular convergent muscle, situated at the chest of the human body. It makes up the bulk of the chest muscles and lies under the breast. Beneath the pectoralis major is the pectoralis minor, a thin, triangular muscle. The pectoralis major's primary functions are flexion, adduction, and internal rotation of the humerus. The pectoral major may colloquially be referred to as "pecs", "pectoral muscle", or "chest muscle", because it is the largest and most superficial muscle in the chest area. Structure It arises from the anterior surface of the sternal half of the clavicle from breadth of the half of the anterior surface of the sternum, as low down as the attachment of the cartilage of the sixth or seventh rib; from the cartilages of all the true ribs, with the exception, frequently, of the first or seventh, and from the aponeurosis of the abdominal external oblique muscle. From this extensive origin the fibers converge toward the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Mammal
Mammals () are a group of vertebrate animals constituting the class Mammalia (), characterized by the presence of mammary glands which in females produce milk for feeding (nursing) their young, a neocortex (a region of the brain), fur or hair, and three middle ear bones. These characteristics distinguish them from reptiles (including birds) from which they diverged in the Carboniferous, over 300 million years ago. Around 6,400 extant species of mammals have been described divided into 29 orders. The largest orders, in terms of number of species, are the rodents, bats, and Eulipotyphla (hedgehogs, moles, shrews, and others). The next three are the Primates (including humans, apes, monkeys, and others), the Artiodactyla ( cetaceans and even-toed ungulates), and the Carnivora (cats, dogs, seals, and others). In terms of cladistics, which reflects evolutionary history, mammals are the only living members of the Synapsida (synapsids); this clade, together with Saur ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
FGF10
Fibroblast growth factor 10 is a protein that in humans is encoded by the ''FGF10'' gene. Function The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. Fibroblast growth factor 10 is a paracrine signaling molecule seen first in the limb bud and organogenesis development. FGF10 starts the developing of limbs and its involved in the branching of morphogenesis in multiple organs such as the lungs, skin, ear and salivary glands. During the limb development Tbx4/Tbx5 stimulate the production of FGF10 in the lateral plate mesoderm where it will create an epithelial-mesenchymal FGF signal with FGF8. This positive feedback loop will increase the amount of mesenchyme resulting in a bulge. Afterwards, FGF10 will induce the f ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Bone Morphogenetic Protein
Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Originally discovered by their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. The important functioning of BMP signals in physiology is emphasized by the multitude of roles for dysregulated BMP signalling in pathological processes. Cancerous disease often involves misregulation of the BMP signalling system. Absence of BMP signalling is, for instance, an important factor in the progression of colon cancer, and conversely, overactivation of BMP signalling following reflux-induced esophagitis provokes Barrett's esophagus and is thus instrumental in the development of esophageal adenocarcinoma. Recombinant human BMPs (rhBMPs) are used in orthopedic applications such as spinal fusions, nonunions, and oral surgery. rhBMP-2 and rhBMP-7 are F ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
|
Enhancer (genetics)
In genetics, an enhancer is a short (50–1500 bp) region of DNA that can be bound by proteins ( activators) to increase the likelihood that transcription of a particular gene will occur. These proteins are usually referred to as transcription factors. Enhancers are ''cis''-acting. They can be located up to 1 Mbp (1,000,000 bp) away from the gene, upstream or downstream from the start site. There are hundreds of thousands of enhancers in the human genome. They are found in both prokaryotes and eukaryotes. The first discovery of a eukaryotic enhancer was in the immunoglobulin heavy chain gene in 1983. This enhancer, located in the large intron, provided an explanation for the transcriptional activation of rearranged Vh gene promoters while unrearranged Vh promoters remained inactive. Locations In eukaryotic cells the structure of the chromatin complex of DNA is folded in a way that functionally mimics the supercoiled state characteristic of prokaryotic DNA, so although the en ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |