Aortoiliac Occlusive Disease
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Aortoiliac Occlusive Disease
In medicine, aortoiliac occlusive disease is a form of central artery disease involving the blockage of the abdominal aorta as it transitions into the common iliac arteries. Signs and symptoms Classically, it is described in male patients as a triad of the following signs and symptoms: # claudication of the buttocks and thighs # absent or decreased femoral pulses # erectile dysfunction This combination is known as Leriche syndrome. However, any number of symptoms may present, depending on the distribution and severity of the disease, such as muscle atrophy, slow wound healing in the legs, and critical limb ischemia. Diagnosis The physical examination usually shows weakened femoral pulses and a reduced ankle-brachial index. The diagnosis can be verified by color duplex scanning, which reveals either a peak systolic velocity ratio ≥2.5 at the site of stenosis and/or a monophasic waveform. MRA and multidetector CTA are often used to determine the extent and type of obstructi ...
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Gray's Anatomy
''Gray's Anatomy'' is a reference book of human anatomy written by Henry Gray, illustrated by Henry Vandyke Carter, and first published in London in 1858. It has gone through multiple revised editions and the current edition, the 42nd (October 2020), remains a standard reference, often considered "the doctors' bible". Earlier editions were called ''Anatomy: Descriptive and Surgical'', ''Anatomy of the Human Body'' and ''Gray's Anatomy: Descriptive and Applied'', but the book's name is commonly shortened to, and later editions are titled, ''Gray's Anatomy''. The book is widely regarded as an extremely influential work on the subject. Publication history Origins The English anatomist Henry Gray was born in 1827. He studied the development of the endocrine glands and spleen and in 1853 was appointed Lecturer on Anatomy at St George's Hospital Medical School in London. In 1855, he approached his colleague Henry Vandyke Carter with his idea to produce an inexpensive and ac ...
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Vascular Bypass
A vascular bypass is a surgical procedure performed to redirect blood flow from one area to another by reconnecting blood vessels. Often, this is done to bypass around a diseased artery, from an area of normal blood flow to another relatively normal area. It is commonly performed due to inadequate blood flow (ischemia) caused by atherosclerosis, as a part of organ transplantation, or for vascular access in hemodialysis. In general, someone's own vein (autograft) is the preferred graft material (or conduit) for a vascular bypass, but other types of grafts such as polytetrafluoroethylene (Teflon), polyethylene terephthalate (Dacron), or a different person's vein (allograft) are also commonly used. Arteries can also serve as vascular grafts. A surgeon sews the graft to the source and target vessels by hand using surgical suture, creating a surgical anastomosis. Common bypass sites include the heart (coronary artery bypass surgery) to treat coronary artery disease, and the legs, where ...
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Vascular Diseases
Vascular disease is a class of diseases of the blood vessels – the arteries and veins of the circulatory system of the body. Vascular disease is a subgroup of cardiovascular disease. Disorders in this vast network of blood vessels can cause a range of health problems that can sometimes become severe. Types There are several types of vascular disease, and signs and symptoms can vary depending on the disease type. These types include: * Erythromelalgia - a rare peripheral vascular disease with syndromes that include burning pain, increased temperature, erythema and swelling that generally affect the hands and feet. * Peripheral artery disease – occurs when atheromatous plaques build up in the arteries that supply blood to the arms and legs, causing the arteries to narrow or become blocked. * Renal artery stenosis - the narrowing of renal arteries that carry blood to the kidneys from the aorta. * Buerger's disease – inflammation and swelling in small blood vessels, cau ...
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Peripheral Arterial Disease
Peripheral artery disease (PAD) is an abnormal narrowing of arteries other than those that supply the heart or brain. When narrowing occurs in the heart, it is called coronary artery disease, and in the brain, it is called cerebrovascular disease. Peripheral artery disease most commonly affects the legs, but other arteries may also be involved – such as those of the arms, neck, or kidneys. The classic symptom is leg pain when walking which resolves with rest, known as intermittent claudication. Other symptoms include skin ulcers, bluish skin, cold skin, or abnormal nail and hair growth in the affected leg. Complications may include an infection or tissue death which may require amputation; coronary artery disease, or stroke. Up to 50% of people with PAD do not have symptoms. The greatest risk factor for PAD is cigarette smoking. Other risk factors include diabetes, high blood pressure, kidney problems, and high blood cholesterol. The most common underlying mechanism of peri ...
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Claudication
Claudication is a medical term usually referring to impairment in walking, or pain, discomfort, numbness, or tiredness in the legs that occurs during walking or standing and is relieved by rest. The perceived level of pain from claudication can be mild to extremely severe. Claudication is most common in the calves but it can also affect the feet, thighs, hips, buttocks, or arms. The word ''claudication'' comes from the Latin ''claudicare'' meaning 'to limp'. Claudication that appears after a short amount of walking may sometimes be described by US medical professionals by the number of typical city street blocks that the patient can walk before the onset of claudication. Thus, "one-block claudication" appears after walking one block, "two-block claudication" appears after walking two blocks, etc. The term ''block'' would be understood more exactly locally but is on the order of 100 metres. Types Intermittent vascular Intermittent vascular (or arterial) claudication (Latin: ' ...
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Hunterian Museum
The Hunterian is a complex of museums located in and operated by the University of Glasgow in Glasgow, Scotland. It is the oldest museum in Scotland. It covers the Hunterian Museum, the Hunterian Art Gallery, the Mackintosh House, the Zoology Museum and the Anatomy Museum, which are all located in various buildings on the main campus of the university in the west end of Glasgow. History In 1783, William Hunter, a Scottish anatomist and physician who studied at the University of Glasgow, died in London. His will stipulated that his substantial and varied collections should be donated to the University of Glasgow. Hunter, writing to Dr William Cullen, stated that they were "to be well and carefully packed up and safely conveyed to Glasgow and delivered to the Principal and Faculty of the College of Glasgow to whom I give and bequeath the same to be kept and preserved by them and their successors for ever... in such sort, way, manner and form as ... shall seem most fit and most c ...
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Anatomy
Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having its beginnings in prehistoric times. Anatomy is inherently tied to developmental biology, embryology, comparative anatomy, evolutionary biology, and phylogeny, as these are the processes by which anatomy is generated, both over immediate and long-term timescales. Anatomy and physiology, which study the structure and function (biology), function of organisms and their parts respectively, make a natural pair of related disciplines, and are often studied together. Human anatomy is one of the essential basic research, basic sciences that are applied in medicine. The discipline of anatomy is divided into macroscopic scale, macroscopic and microscopic scale, microscopic. Gross anatomy, Macroscopic anatomy, or gross anatomy, is the examination of an ...
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Pathophysiology
Pathophysiology ( physiopathology) – a convergence of pathology with physiology – is the study of the disordered physiological processes that cause, result from, or are otherwise associated with a disease or injury. Pathology is the medical discipline that describes conditions typically ''observed'' during a disease state, whereas physiology is the biological discipline that describes processes or mechanisms ''operating'' within an organism. Pathology describes the abnormal or undesired condition, whereas pathophysiology seeks to explain the functional changes that are occurring within an individual due to a disease or pathologic state. History Etymology The term ''pathophysiology'' comes from the Ancient Greek πάθος (''pathos'') and φυσιολογία (''phusiologia''). Nineteenth century Reductionism In Germany in the 1830s, Johannes Müller led the establishment of physiology research autonomous from medical research. In 1843, the Berlin Physical Socie ...
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French People
The French people (french: Français) are an ethnic group and nation primarily located in Western Europe that share a common French culture, history, and language, identified with the country of France. The French people, especially the native speakers of langues d'oïl from northern and central France, are primarily the descendants of Gauls (including the Belgae) and Romans (or Gallo-Romans, western European Celtic and Italic peoples), as well as Germanic peoples such as the Franks, the Visigoths, the Suebi and the Burgundians who settled in Gaul from east of the Rhine after the fall of the Roman Empire, as well as various later waves of lower-level irregular migration that have continued to the present day. The Norse also settled in Normandy in the 10th century and contributed significantly to the ancestry of the Normans. Furthermore, regional ethnic minorities also exist within France that have distinct lineages, languages and cultures such as Bretons in Brittany, Occi ...
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René Leriche
Henri Marie René Leriche (12 October 1879 – 28 December 1955) was a French vascular surgeon and physiologist. He was a specialist in pain, vascular surgery and the sympathetic trunk. He sensitized many who were mutilated in the first World war, he was the first to be interested in pain and to practice gentle surgery with as little trauma as possible. Two symptoms have the name Algoneurodystrophy and the aortic iliac obliteration. He has trained many students, such as Michael E. DeBakey, Jão Cid dos Santos, René Fontaine et Jean Kunlino. Biography He came from a family of Lyonian doctors, his father Ernest Leriche is confessed near the civil court of Roanne (after studying law in Paris) and his mother Anne Chamussy, married to Leriche, belong to the elite industrial region. Rene Leriche was the third child of seven siblings. He is the brother of Marc Leriche, a French sculptor. He attended at the school of Maristes. In 1893, he obtained a bachelor's degree in rheto ...
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Robert Graham (botanist)
Robert Graham (3 December 1786 – 7 August 1845) was a Scottish physician and botanist. Life Graham was born in Stirling Stirling (; sco, Stirlin; gd, Sruighlea ) is a city in central Scotland, northeast of Glasgow and north-west of Edinburgh. The market town, surrounded by rich farmland, grew up connecting the royal citadel, the medieval old town with its me ... the son of Dr Robert Graham, physician. After studying at Stirling Grammar School he continued first to the University of Glasgow and then to the University of Edinburgh where he graduated around 1806, and completed his Doctor of Medicine, MD in 1808. He trained further at St Bartholomew's Hospital, London, where he qualified as a surgeon. He then returned to Scotland to practice at Glasgow Royal Infirmary 1812-3 and 1816–19. In 1816 he began lecturing in botany at the University of Glasgow, taking over from Thomas Brown of Lanfine and Waterhaughs following his resignation. He was a major figure in the cr ...
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Vascular Bypass
A vascular bypass is a surgical procedure performed to redirect blood flow from one area to another by reconnecting blood vessels. Often, this is done to bypass around a diseased artery, from an area of normal blood flow to another relatively normal area. It is commonly performed due to inadequate blood flow (ischemia) caused by atherosclerosis, as a part of organ transplantation, or for vascular access in hemodialysis. In general, someone's own vein (autograft) is the preferred graft material (or conduit) for a vascular bypass, but other types of grafts such as polytetrafluoroethylene (Teflon), polyethylene terephthalate (Dacron), or a different person's vein (allograft) are also commonly used. Arteries can also serve as vascular grafts. A surgeon sews the graft to the source and target vessels by hand using surgical suture, creating a surgical anastomosis. Common bypass sites include the heart (coronary artery bypass surgery) to treat coronary artery disease, and the legs, where ...
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