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Anterior Temporal Lobectomy
Anterior temporal lobectomy is the complete or partial removal of the anterior portion of the temporal lobe of the brain. The exact boundaries for removal can vary slightly in practice and between neurosurgeons. It is a treatment option for temporal lobe epilepsy for those in whom anticonvulsant medications do not control epileptic seizures, and who have frequent seizures, and who additionally qualify based on a WADA test to localize the dominant hemisphere for language module. __TOC__ Techniques The techniques for removing temporal lobe tissue vary from resection of large amounts of tissue, including lateral temporal cortex along with medial structures, from using more restricted anterior temporal lobectomy (ATL) to more restricted removal of only the medial structures (selective amygdalohippocampectomy). Nearly all reports of seizure outcome following these procedures indicate that the best outcome group includes patients with MRI evidence of mesial temporal sclerosis (hippoca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lobectomy
Lobectomy means ''surgical excision of a lobe''. This may refer to a lobe of the lung (also simply called a lobectomy), a lobe of the thyroid (hemithyroidectomy), a lobe of the brain (as in anterior temporal lobectomy), or a lobe of the liver (hepatectomy). __TOC__ Lung lobectomy A lobectomy of the lung is performed in early-stage non-small cell lung cancer patients. It is not performed on patients that have lung cancer that has spread to other parts of the body. Tumor size, type, and location are major factors as to whether a lobectomy is performed. This can be due to cancer or smoking. Lung lobectomies are performed on patients as young as eleven or twelve who have no cancer or smoking history, but have conditions from birth or early childhood that necessitate the operation. Such patients will have reduced lung capacity which tends to limit their range of activities through life. They often need to use inhalers on a daily basis, and are often classified as being asthma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Transfusion
Blood transfusion is the process of transferring blood products into a person's circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used whole blood, but modern medical practice commonly uses only components of the blood, such as red blood cells, white blood cells, plasma, clotting factors and platelets. Red blood cells (RBC) contain hemoglobin, and supply the cells of the body with oxygen. White blood cells are not commonly used during transfusion, but they are part of the immune system, and also fight infections. Plasma is the "yellowish" liquid part of blood, which acts as a buffer, and contains proteins and important substances needed for the body's overall health. Platelets are involved in blood clotting, preventing the body from bleeding. Before these components were known, doctors believed that blood was homogeneous. Because of this scientific misunderstanding, many patients died b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epilepsy
Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrical activity in the brain. These episodes can result in physical injuries, either directly such as broken bones or through causing accidents. In epilepsy, seizures tend to recur and may have no immediate underlying cause. Isolated seizures that are provoked by a specific cause such as poisoning are not deemed to represent epilepsy. People with epilepsy may be treated differently in various areas of the world and experience varying degrees of social stigma due to the alarming nature of their symptoms. The underlying mechanism of epileptic seizures is excessive and abnormal neuronal activity in the cortex of the brain which can be observed in the electroencephalogram (EEG) of an individual. The reason this occurs in most cases of epilepsy is u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hippocampus (anatomy)
The hippocampus (via Latin from Ancient Greek, Greek , 'seahorse') is a major component of the brain of humans and other vertebrates. Humans and other mammals have two hippocampi, one in each cerebral hemisphere, side of the brain. The hippocampus is part of the limbic system, and plays important roles in the Memory consolidation, consolidation of information from short-term memory to long-term memory, and in spatial memory that enables navigation. The hippocampus is located in the allocortex, with neural projections into the neocortex in humans, as well as primates. The hippocampus, as the Pallium (neuroanatomy)#In humans, medial pallium, is a structure found in all vertebrates. In humans, it contains two main interlocking parts: the hippocampus proper (also called ''Ammon's horn''), and the dentate gyrus. In Alzheimer's disease (and other forms of dementia), the hippocampus is one of the first regions of the brain to suffer damage; short-term memory, short-term memory loss and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-acetyl Aspartate
''N''-Acetylaspartic acid, or ''N''-acetylaspartate (NAA), is a derivative of aspartic acid with a formula of C6H9NO5 and a molecular weight of 175.139. NAA is the second-most-concentrated molecule in the brain after the amino acid glutamate. It is detected in the adult brain in neurons, oligodendrocytes and myelin and is synthesized in the mitochondria from the amino acid aspartic acid and acetyl-coenzyme A. Function The various functions served by NAA are under investigation, but the primary proposed functions include: * Neuronal osmolyte that is involved in fluid balance in the brain * Source of acetate for lipid and myelin synthesis in oligodendrocytes, the glial cells that myelinate neuronal axons * Precursor for the synthesis of the neuronal dipeptide N-Acetylaspartylglutamate * Contributor to energy production from the amino acid glutamate in neuronal mitochondria In the brain, NAA was thought to be present predominantly in neuronal cell bodies, where it acts as a n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Open Surgery
Minimally invasive procedures (also known as minimally invasive surgeries) encompass surgical techniques that limit the size of incisions needed, thereby reducing wound healing time, associated pain, and risk of infection. Surgery by definition is invasive and many operations requiring incisions of some size are referred to as ''open surgery''. Incisions made during open surgery can sometimes leave large wounds that may be painful and take a long time to heal. Advancements in medical technologies have enabled the development and regular use of minimally invasive procedures. For example, endovascular aneurysm repair, a minimally invasive surgery, has become the most common method of repairing abdominal aortic aneurysms in the US as of 2003. The procedure involves much smaller incisions than the corresponding open surgery procedure of open aortic surgery. Interventional radiologists were the forerunners of minimally invasive procedures. Using imaging techniques, radiologists wer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mesial Temporal Lobe Epilepsy
Temporal lobe epilepsy (TLE) is a chronic condition, chronic disorder of the nervous system which is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the human brain, brain and last about one or two minutes. TLE is the most common form of epilepsy with focal seizures. A focal seizure in the temporal lobe may spread to other areas in the brain when it may become a ''focal to bilateral seizure''. TLE is diagnosed by taking a medical history, blood tests, and neuroimaging, brain imaging. It can have a number of causes such as head injury, stroke, brain infections, structural Brain lesion, lesions in the brain, brain tumors, or it can be of ''unknown onset''. The first line of treatment is through anticonvulsant medication, anticonvulsants. Surgery may be an option, especially when there is an observable abnormality in the brain. Another treatment option is electrical stimulation of the brain through an implanted device called the vagus ner ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intensive Care Unit
220px, Intensive care unit An intensive care unit (ICU), also known as an intensive therapy unit or intensive treatment unit (ITU) or critical care unit (CCU), is a special department of a hospital or health care facility that provides intensive care medicine. Intensive care units cater to patients with severe or life-threatening illnesses and injuries, which require constant care, close supervision from life support equipment and medication in order to ensure normal bodily functions. They are staffed by highly trained physicians, nurses and respiratory therapists who specialize in caring for critically ill patients. ICUs are also distinguished from general hospital wards by a higher staff-to-patient ratio and access to advanced medical resources and equipment that is not routinely available elsewhere. Common conditions that are treated within ICUs include acute respiratory distress syndrome, septic shock, and other life-threatening conditions. Patients may be referred dire ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mesial Temporal Sclerosis
Hippocampal sclerosis (HS) or mesial temporal sclerosis (MTS) is a Neuropathology, neuropathological condition with severe neuronal cell loss and gliosis in the hippocampus, specifically in the Cornu Ammonis area 1, CA-1 (Cornu Ammonis area 1) and subiculum of the hippocampus. It was first described in 1880 by Wilhelm Sommer. Hippocampal Sclerosis (medicine), sclerosis is a frequent pathologic finding in community-based dementia. Hippocampal sclerosis can be detected with autopsy or MRI. In MRI, a decrease in signal is observed at Spin–lattice relaxation, T1 and an increase in signal at Spin–spin relaxation, T2. Positron emission tomography is also used as an aid for diagnosis. In Positron emission tomography, PET examination, glucose uptake is lower than in the normal part. The reason for this is that the sclerotic part works at a lower level than the normal part and needs less energy. Individuals with hippocampal sclerosis have similar initial symptoms and rates of dementia pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Temporal Lobe
The temporal lobe is one of the four Lobes of the brain, major lobes of the cerebral cortex in the brain of mammals. The temporal lobe is located beneath the lateral fissure on both cerebral hemispheres of the mammalian brain. The temporal lobe is involved in processing sensory input into derived meanings for the appropriate retention of visual memory, language comprehension, and emotion association. ''Temporal'' refers to the head's Temple (anatomy), temples. Structure The Temple (anatomy)#Etymology, temporal Lobe (anatomy), lobe consists of structures that are vital for declarative or long-term memory. Declarative memory, Declarative (denotative) or Explicit memory, explicit memory is conscious memory divided into semantic memory (facts) and episodic memory (events). Medial temporal lobe structures that are critical for long-term memory include the hippocampus, along with the surrounding Hippocampal formation, hippocampal region consisting of the Perirhinal cortex, perirhinal, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amygdalohippocampectomy
Amygdalohippocampectomy is a surgical procedure for the treatment of epilepsy. It consists of the removal of the hippocampus, which has a role in memory, spatial awareness, and navigation, and the amygdalae, which have a role in the processing and memory of emotional reactions, both structures forming part of the limbic system of the brain. Amygdalohippocampectomy is used only when all other treatment options have failed to resolve the epilepsy. It is an effective treatment for most patients. However, possible adverse side effects include impaired memory and defects in visual perception. __TOC__ Procedure The amygdalohippocampectomy is indicated when the focal point of the seizures can be anatomically localized to the hippocampus and amygdala. Normally, to be considered for this procedure, one must have failed all first-line treatments. The selective amygdalohippocampectomy will remove only the offending portions of the hippocampus and amygdala. When data from studies of the el ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Language Module
The language module or language faculty is a hypothetical structure in the human brain which is thought to contain innate capacities for language, originally posited by Noam Chomsky. There is ongoing research into brain modularity in the fields of cognitive science and neuroscience, although the current idea is much weaker than what was proposed by Chomsky and Jerry Fodor in the 1980s. In today's terminology, 'modularity' refers to specialisation: language processing is specialised in the brain to the extent that it occurs partially in different areas than other types of information processing such as visual input. The current view is, then, that language is neither compartmentalised nor based on general principles of processing (as proposed by George Lakoff). It is modular to the extent that it constitutes a specific cognitive skill or area in cognition. Meaning of a module The notion of a dedicated language module in the human brain originated with Noam Chomsky's theory of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
