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Annonamine
Annonamine is a benzylisoquinoline alkaloid isolated from ''Annona muricata'' (commonly known as soursop, graviola, guanabana, paw-paw and sirsak), a plant commonly used in folk medicine by indigenous communities in Africa and South America. Structurally, it contains an aporphine core featuring a quaternary ammonium group. See also * Asimilobine - amine not quaternized * Anonaine * Pukateine Pukateine is an alkaloid found in the bark of the New Zealand tree ''Laurelia novae-zelandiae'' ("Pukatea"), as well as some South American plants. An extract from pukatea is used in traditional Māori culture, Māori herbal medicine as an analge ... References Aporphine alkaloids {{alkaloid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Annona Muricata
Soursop (also called ''graviola, guyabano'', and in Hispanic America, ''guanábana'') is the fruit of ''Annona muricata'', a broadleaf, flowering, evergreen tree. It is native to the tropical regions of the Americas and the Caribbean and is widely propagated. It is in the same genus, '' Annona'', as cherimoya and is in the Annonaceae family. The soursop is adapted to areas of high humidity and relatively warm winters; temperatures below will cause damage to leaves and small branches, and temperatures below can be fatal. The fruit becomes dry and is no longer good for concentrate. With an aroma similar to pineapple, the flavor of the fruit has been described as a combination of strawberries and apple with sour citrus flavor notes, contrasting with an underlying thick creamy texture reminiscent of banana. Soursop is widely promoted (sometimes as "graviola") as an alternative cancer treatment, but there is no reliable medical evidence it is effective for treating cancer or an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzylisoquinoline
Substitution of the heterocycle isoquinoline at the C1 position by a benzyl group provides 1‑benzylisoquinoline, the most widely examined of the numerous benzylisoquinoline structural isomers. The 1-benzylisoquinoline moiety can be identified within numerous compounds of pharmaceutical interest, such as moxaverine; but most notably it is found within the structures of a wide variety of plant natural products, collectively referred to as benzylisoquinoline alkaloids. This class is exemplified in part by the following compounds: papaverine, noscapine, codeine, morphine, apomorphine, berberine, tubocurarine. Biosynthesis (''S'')-Norcoclaurine (higenamine) has been identified as the central 1-benzyl-tetrahydro-isoquinoline precursor from which numerous complex biosynthetic pathways eventually emerge. These pathways collectively lead to the structurally disparate compounds comprising the broad classification of plant natural products referred to as benzylisoquinoline alkaloids (BIA), ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloid
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids xumuk.ru Alkaloids are produced by a large variety of organisms including , , Medicinal plant, plants, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aporphine
Aporphine is an alkaloid with the chemical formula . The IUPAC (International Union of Pure and Applied Chemistry) name of aporphine is ''6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo e,guinoline.'' It is the core chemical substructure of the aporphine alkaloids, a subclass of quinoline alkaloids. It can exist in either of two enantiomeric forms, (''R'')-aporphine and (''S'')-aporphine. Derivatives Many different derivatives have been isolated from plants. For example, many water-lilies (''Nymphaea'' species) produce aporphine alkaloids such as nymphaeine, nymphaline, nupharine, α- and β- nupharidine. ''In vitro'' tests of some aporphine derivatives isolated from ''Cassytha filiformis'', namely actinodaphnine, cassythine, and dicentrine, showed antiparasitic activity against ''Trypanosoma brucei''. Investigation of possible mechanisms revealed that the compounds bind to DNA and act as intercalating agents, besides inhibiting topoisomerase activity. Aporphine natural products o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quaternary Ammonium
In chemistry, quaternary ammonium cations, also known as quats, are positively charged polyatomic ions of the structure , R being an alkyl group or an aryl group. Unlike the ammonium ion () and the primary, secondary, or tertiary ammonium cations, the quaternary ammonium cations are permanently charged, independent of the pH of their solution. Quaternary ammonium salts or quaternary ammonium compounds (called quaternary amines in oilfield parlance) are salts of quaternary ammonium cations. Polyquats are a variety of engineered polymer forms which provide multiple quat molecules within a larger molecule. Quats are used in consumer applications including as antimicrobials (such as detergents and disinfectants), fabric softeners, and hair conditioners. As an antimicrobial, they are able to inactivate enveloped viruses (such as SARS-CoV-2). Quats tend to be gentler on surfaces than bleach-based disinfectants, and are generally fabric-safe. Synthesis Quaternary ammonium comp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quaternary Compound
In chemistry, a quaternary compound is a compound consisting of exactly four chemical elements. In another use of the term in organic chemistry, a quaternary compound is or has a cation consisting of a central positively charged atom with four substituents, especially organic (alkyl and aryl) groups, discounting hydrogen atoms. The best-known quaternary compounds are quaternary ammonium salts, having a nitrogen atom at the centre. For example, in the following reaction, the nitrogen atom is said to be quaternized as it has gone from 3 to 4 substituents: :R3N + RCl -> R4N+Cl- Other examples include substituted phosphonium salts (), substituted arsonium salts () like arsenobetaine, as well as some arsenic-containing superconductors. Substituted stibonium () and bismuthonium salts () have also been described. See also *Binary compound *Ternary compound *Onium ion *Quaternary phase In materials chemistry, a quaternary phase is a chemical compound containing four element ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anonaine
Anonaine is a bioactive benzylisoquinoline alkaloid, present in members of the plant families Magnoliaceae and Annonaceae It is named after the plant it was first extracted from, ''Annona reticulata'', which is commonly known as Anona. Extraction from Annonaceae The alkaloid was first isolated from the bark of the ''Annona reticulata''. It has since been found in ''Annona squamosa'', the leaves of ''Michelia'' × ''alba'', ''Fissistigma latifolium'' and ''Goniothalamus australis'', among many others. The compound may be obtained by dry roasting the bark of Annona reticulata and extracting with methanol. The methanol is removed and the resulting syrup is then treated with hydrochloric acid and the insoluble salts filtered off. The filtrate can then made basic with NH4OH and extracted with diethyl ether. Shaking the extract with 5% sodium hydroxide and retaining the organic layer removes the phenolic content of the extract. The hydrogen chloride salt is then obtained by mixing with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pukateine
Pukateine is an alkaloid found in the bark of the New Zealand tree ''Laurelia novae-zelandiae'' ("Pukatea"), as well as some South American plants. An extract from pukatea is used in traditional Māori culture, Māori herbal medicine as an analgesic. Bernard Cracroft Aston studied the physical and chemical characteristics of the compound, and presented a paper with his findings to the Royal Society of New Zealand on 11 May 1909. See also References Aporphine alkaloids Analgesics Phenols Dopamine agonists Benzodioxoles {{analgesic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
