Ampullary Cupula
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Ampullary Cupula
The ampullary cupula, or cupula, is a structure in the vestibular system, providing the sense of spatial orientation. The cupula is located within the ampullae of each of the three semicircular canals. Part of the crista ampullaris, the cupula has embedded within it hair cells that have several stereocilia associated with each kinocilium. The cupula itself is the gelatinous component of the crista ampullaris that extends from the crista to the roof of the ampullae. When the head rotates, the endolymph filling the semicircular ducts initially lags behind due to inertia. As a result, the cupula is deflected opposite the direction of head movement. As the endolymph pushes the cupula, the stereocilia is bent as well, stimulating the hair cells within the crista ampullaris. After a short time of continual rotation however, the endolymph's acceleration normalizes with the rate of rotation of the semicircular ducts. As a result, the cupula returns to its resting position and the hair cel ...
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Vestibular System's Semicircular Canal- A Cross-section
The Vestibular (from pt, vestíbulo, "entrance hall") is a competitive examination and is the primary and widespread entrance system used by Brazilian universities to select the students admitted. The Vestibular usually takes place from November to January, right before the start of school year in February or March, although certain universities hold it every semester. The exams often span several days, usually two, with different disciplines being tested each day. Structure Several Brazilian universities follow the FUVEST (University of São Paulo's entry exam) pattern, which is divided into two stages or "phases". The first stage consists of 90 multiple choice questions, including subjects such as Portuguese Language, Portuguese Literature and Brazilian Literature; Math, History, Geography, Biology, Physics, Chemistry and Foreign Language. The answers are marked on an answer card, and they are graded afterwards by an automated optical reader. Some institutions establish a ...
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Vestibular System
The vestibular system, in vertebrates, is a sensory system that creates the sense of balance and spatial orientation for the purpose of coordinating movement with balance. Together with the cochlea, a part of the auditory system, it constitutes the labyrinth of the inner ear in most mammals. As movements consist of rotations and translations, the vestibular system comprises two components: the semicircular canals, which indicate rotational movements; and the otoliths, which indicate linear accelerations. The vestibular system sends signals primarily to the neural structures that control eye movement; these provide the anatomical basis of the vestibulo-ocular reflex, which is required for clear vision. Signals are also sent to the muscles that keep an animal upright and in general control posture; these provide the anatomical means required to enable an animal to maintain its desired position in space. The brain uses information from the vestibular system in the head and fro ...
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Spatial Orientation
In geometry, the orientation, angular position, attitude, bearing, or direction of an object such as a line, plane or rigid body is part of the description of how it is placed in the space it occupies. More specifically, it refers to the imaginary rotation that is needed to move the object from a reference placement to its current placement. A rotation may not be enough to reach the current placement. It may be necessary to add an imaginary translation, called the object's location (or position, or linear position). The location and orientation together fully describe how the object is placed in space. The above-mentioned imaginary rotation and translation may be thought to occur in any order, as the orientation of an object does not change when it translates, and its location does not change when it rotates. Euler's rotation theorem shows that in three dimensions any orientation can be reached with a single rotation around a fixed axis. This gives one common way of representing ...
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Osseous Ampullae
The semicircular canals or semicircular ducts are three semicircular, interconnected tubes located in the innermost part of each ear, the inner ear. The three canals are the horizontal, superior and posterior semicircular canals. Structure The semicircular canals are a component of the bony labyrinth that are at right angles from each other. At one end of each of the semicircular canals is a dilated sac called an osseous ampulla, which is more than twice the diameter of the canal. Each ampulla contains an ampullary crest, the crista ampullaris which consists of a thick gelatinous cap called a cupula and many hair cells. The superior and posterior semicircular canals are oriented vertically at right angles to each other. The lateral semicircular canal is about a 30-degree angle from the horizontal plane. The orientations of the canals cause a different canal to be stimulated by movement of the head in different planes, and more than one canal is stimulated at once if the movement ...
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Semicircular Canal
In mathematics (and more specifically geometry), a semicircle is a one-dimensional locus of points that forms half of a circle. The full arc of a semicircle always measures 180° (equivalently, radians, or a half-turn). It has only one line of symmetry (reflection symmetry). In non-technical usage, the term "semicircle" is sometimes used to refer to a half-disk, which is a two-dimensional geometric shape that also includes the diameter segment from one end of the arc to the other as well as all the interior points. By Thales' theorem, any triangle inscribed in a semicircle with a vertex at each of the endpoints of the semicircle and the third vertex elsewhere on the semicircle is a right triangle, with a right angle at the third vertex. All lines intersecting the semicircle perpendicularly are concurrent at the center of the circle containing the given semicircle. Uses A semicircle can be used to construct the arithmetic and geometric means of two lengths using straight-e ...
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Crista Ampullaris
The crista ampullaris is the sensory organ of rotation. They are found in the osseous ampullae, ampullae of each of the semicircular canals of the inner ear, meaning that there are three pairs in total. The function of the crista ampullaris is to sense angular acceleration and deceleration. Background The inner ear comprises three specialized regions of the membranous labyrinth: the vestibular sacs – the utricle (ear), utricle and saccule, and the semicircular canals, which are the vestibular organs, as well as the cochlear duct, which is involved in the special sense of Hearing (sense), hearing. The semicircular canals are filled with endolymph due to its connection with the cochlear duct via the saccule, which also contains endolymph. It also contains an inner membranous sleeve that lines the semicircular canals. The canals also contain the crista ampullaris. The hair cell, receptor cells located in the semicircular ducts are innervated by the eighth cranial nerve, the vestib ...
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Endolymph
Endolymph is the fluid contained in the membranous labyrinth of the inner ear. The major cation in endolymph is potassium, with the values of sodium and potassium concentration in the endolymph being 0.91  mM and 154  mM, respectively. It is also called ''Scarpa's fluid'', after Antonio Scarpa. Structure The inner ear has two parts: the bony labyrinth and the membranous labyrinth. The membranous labyrinth is contained within the bony labyrinth, and within the membranous labyrinth is a fluid called endolymph. Between the outer wall of the membranous labyrinth and the wall of the bony labyrinth is the location of perilymph. Composition Perilymph and endolymph have unique ionic compositions suited to their functions in regulating electrochemical impulses of hair cells. The electric potential of endolymph is ~80-90 mV more positive than perilymph due to a higher concentration of K compared to Na. The main component of this unique extracellular fluid is potassium, which is ...
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Hair Cell
Hair cells are the sensory receptors of both the auditory system and the vestibular system in the ears of all vertebrates, and in the lateral line organ of fishes. Through mechanotransduction, hair cells detect movement in their environment. In mammals, the auditory hair cells are located within the spiral organ of Corti on the thin basilar membrane in the cochlea of the inner ear. They derive their name from the tufts of stereocilia called ''hair bundles'' that protrude from the apical surface of the cell into the fluid-filled cochlear duct. The stereocilia number from 50-100 in each cell while being tightly packed together and decrease in size the further away they are located from the kinocilium. The hair bundles are arranged as stiff columns that move at their base in response to stimuli applied to the tips. Mammalian cochlear hair cells are of two anatomically and functionally distinct types, known as outer, and inner hair cells. Damage to these hair cells results in ...
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Vestibulocochlear Nerve
The vestibulocochlear nerve or auditory vestibular nerve, also known as the eighth cranial nerve, cranial nerve VIII, or simply CN VIII, is a cranial nerve that transmits sound and equilibrium (balance) information from the inner ear to the brain. Through olivocochlear fibers, it also transmits motor and modulatory information from the superior olivary complex in the brainstem to the cochlea. Structure The vestibulocochlear nerve consists mostly of bipolar neurons and splits into two large divisions: the cochlear nerve and the vestibular nerve. Cranial nerve 8, the vestibulocochlear nerve, goes to the middle portion of the brainstem called the pons (which then is largely composed of fibers going to the cerebellum). The 8th cranial nerve runs between the base of the pons and medulla oblongata (the lower portion of the brainstem). This junction between the pons, medulla, and cerebellum that contains the 8th nerve is called the cerebellopontine angle. The vestibulocochlear nerv ...
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Kinocilia
A kinocilium is a special type of cilium on the apex of hair cells located in the sensory epithelium of the vertebrate inner ear. Anatomy in humans Kinocilia are found on the apical surface of hair cells and are involved in both the morphogenesis of the hair bundle and mechanotransduction. Vibrations (either by movement or sound waves) cause displacement of the hair bundle, resulting in depolarization or hyperpolarization of the hair cell. The depolarization of the hair cells in both instances causes signal transduction via neurotransmitter release. Role in hair bundle morphogenesis Each hair cell has a single, microtubular kinocilium. Before morphogenesis of the hair bundle, the kinocilium is found in the center of the apical surface of the hair cell surrounded by 20-300 microvilli. During hair bundle morphogenesis, the kinocilium moves to the cell periphery dictating hair bundle orientation. As the kinocilium does not move, microvilli surrounding it begin to elongate and form ...
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Vertigo (medical)
Vertigo is a condition where a person has the sensation of movement or of surrounding objects moving when they are not. Often it feels like a spinning or swaying movement. This may be associated with nausea, vomiting, sweating, or difficulties walking. It is typically worse when the head is moved. Vertigo is the most common type of dizziness. The most common disorders that result in vertigo are benign paroxysmal positional vertigo (BPPV), Ménière's disease, and labyrinthitis. Less common causes include stroke, brain tumors, brain injury, multiple sclerosis, migraines, trauma, and uneven pressures between the middle ears. Physiologic vertigo may occur following being exposed to motion for a prolonged period such as when on a ship or simply following spinning with the eyes closed. Other causes may include toxin exposures such as to carbon monoxide, alcohol, or aspirin. Vertigo typically indicates a problem in a part of the vestibular system. Other causes of dizziness include ...
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Sensory Organs
A sense is a biological system used by an organism for sensation, the process of gathering information about the world through the detection of stimuli. (For example, in the human body, the brain which is part of the central nervous system receives signals from the senses which continuously receive information from the environment, interprets these signals, and causes the body to respond, either chemically or physically.) Although traditionally five human senses were identified as such (namely sight, smell, touch, taste, and hearing), it is now recognized that there are many more. Senses used by non-human organisms are even greater in variety and number. During sensation, sense organs collect various stimuli (such as a sound or smell) for transduction, meaning transformation into a form that can be understood by the brain. Sensation and perception are fundamental to nearly every aspect of an organism's cognition, behavior and thought. In organisms, a sensory organ consist ...
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