Agnuside
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Agnuside
Agnuside is a chemical compound found in ''Vitex agnus-castus''. Agnuside is the ester of aucubin Aucubin is an iridoid glycoside. Iridoids are commonly found in plants and function as defensive compounds. Iridoids decrease the growth rates of many generalist herbivores. Natural occurrences Aucubin, as other iridoids, is found in asterids ... and ''p''-hydroxybenzoic acid. References Iridoid glycosides Phenol glucosides Cyclopentenes {{ester-stub ...
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Aucubin
Aucubin is an iridoid glycoside. Iridoids are commonly found in plants and function as defensive compounds. Iridoids decrease the growth rates of many generalist herbivores. Natural occurrences Aucubin, as other iridoids, is found in asterids such as ''Aucuba japonica'' (Garryaceae), ''Eucommia ulmoides'' (Eucommiaceae), ''Plantago asiatica'', ''Plantago major'', ''Plantago lanceolata'' (Plantaginaceae), ''Galium aparine'' (Rubiaceae) and others. These plants are used in traditional Chinese and folk medicine. Agnuside is composed of aucubin and ''p''-hydroxybenzoic acid. Health effects Aucubin was found to protect against liver damage induced by carbon tetrachloride or alpha-amanitin in mice and rats when 80 mg/kg was dosed intraperitoneally. Chemistry Aucubin is a monoterpenoid based compound. Aucubin, like all iridoids, has a cyclopentan- pyran skeleton. Iridoids can consist of ten, nine, or rarely eight carbons in which C11 is more frequently missing than C10. ...
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4-Hydroxybenzoic Acid
4-Hydroxybenzoic acid, also known as ''p''-hydroxybenzoic acid (PHBA), is a monohydroxybenzoic acid, a phenolic derivative of benzoic acid. It is a white crystalline solid that is slightly soluble in water and chloroform but more soluble in polar organic solvents such as alcohols and acetone. 4-Hydroxybenzoic acid is primarily known as the basis for the preparation of its esters, known as parabens, which are used as preservatives in cosmetics and some ophthalmic solutions. It is isomeric with 2-hydroxybenzoic acid, known as salicylic acid, a precursor to aspirin, and with 3-hydroxybenzoic acid. Natural occurrences It is found in plants of the genus ''Vitex'' such as '' V. agnus-castus'' or '' V. negundo'', and in ''Hypericum perforatum'' (St John's wort). It is also found in '' Spongiochloris spongiosa'', a freshwater green alga. The compound is also found in '' Ganoderma lucidum'', a medicinal mushroom with the longest record of use. ''Cryptanaerobacter phenolicus'' is ...
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Vitex Agnus-castus
''Vitex agnus-castus'', also called vitex, chaste tree (or chastetree), chasteberry, Abraham's balm, lilac chastetree, or monk's pepper, is a native of the Mediterranean region. It is one of the few temperate-zone species of ''Vitex'', which is on the whole a genus of tropical and sub-tropical flowering plants.David J. Mabberley. 2008. ''Mabberley's Plant-Book'' third edition (2008). Cambridge University Press: UK. Theophrastus mentioned the shrub several times, as ''agnos'' (άγνος) in ''Enquiry into Plants''. It has been long believed to be an anaphrodisiac – leading to its name as ''chaste tree'' – but its effectiveness for such action remains unproven. Vitex is a cross-pollinating plant, but its self-pollination has been recorded.Verein für Arznei- und Gewürzpflanzen Saluplanta. 2013. ''Handbuch des Arznei- und Gewürzpflanzenbaus'' volume 5 Arznei- und Gewürzpflanzen L-Z, pages 192-199. Verein für Arznei- und Gewürzpflanzen Saluplanta: Bernburg, Germany ...
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Ester
In chemistry, an ester is a compound derived from an oxoacid (organic or inorganic) in which at least one hydroxyl group () is replaced by an alkoxy group (), as in the substitution reaction of a carboxylic acid and an alcohol. Glycerides are fatty acid esters of glycerol; they are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Phosphoesters form the backbone of DNA molecules. Nitrate esters, such as nitroglycerin, are known for their explosive properties. '' Nomenclature Etymology Th ...
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Iridoid Glycosides
Iridoids are a type of monoterpenoids in the general form of cyclopentanopyran, found in a wide variety of plants and some animals. They are biosynthetically derived from 8-oxogeranial. Iridoids are typically found in plants as glycosides, most often bound to glucose. The chemical structure is exemplified by iridomyrmecin, a defensive chemical produced by the ant genus ''Iridomyrmex'', for which iridoids are named. Structurally, they are bicyclic ''cis''-fused cyclopentane-pyrans. Cleavage of a bond in the cyclopentane ring gives rise to a subclass known as ''secoiridoids'', such as oleuropein and amarogentin. Occurrence The iridoids produced by plants act primarily as a defense against herbivores or against infection by microorganisms. The variable checkerspot butterfly also contains iridoids obtained through its diet which act as a defense against avian predators. To humans and other mammals, iridoids are often characterized by a deterrent bitter taste. Aucubin and catal ...
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Phenol Glucosides
Phenol (also called carbolic acid) is an aromatic organic compound with the molecular formula . It is a white crystalline solid that is volatile. The molecule consists of a phenyl group () bonded to a hydroxy group (). Mildly acidic, it requires careful handling because it can cause chemical burns. Phenol was first extracted from coal tar, but today is produced on a large scale (about 7 billion kg/year) from petroleum-derived feedstocks. It is an important industrial commodity as a precursor to many materials and useful compounds. It is primarily used to synthesize plastics and related materials. Phenol and its chemical derivatives are essential for production of polycarbonates, epoxies, Bakelite, nylon, detergents, herbicides such as phenoxy herbicides, and numerous pharmaceutical drugs. Properties Phenol is an organic compound appreciably soluble in water, with about 84.2 g dissolving in 1000 mL (0.895 M). Homogeneous mixtures of phenol and water at phenol to wate ...
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