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Asarone
Asarone is chemical compound of the phenylpropanoid class found in certain plants such as ''Acorus'' and ''Asarum''. There are two isomers, α (or ''trans'') and β (or ''cis''). As a volatile fragrance oil, it is used in killing pests and bacteria. Pharmacology The main clinical symptom of asarone is prolonged vomiting that sometimes lasted more than 15 hours. Asarone is not metabolized to trimethoxyamphetamine as has been claimed by online vendors. The Council of Europe Committee of Experts on Flavouring Substances concluded that β-asarone is clearly carcinogenic and has proposed limits for its concentration in flavorings such as bitters made from ''Acorus calamus'' (sweet flag). β-Asarone exhibits anti-fungal activity by inhibiting ergosterol biosynthesis in ''Aspergillus niger''. However, the toxicity and carcinogenicity of asarone means that it may be difficult to develop any practical medication based on it. See also * Elemicin Elemicin is a phenylpropene, a nat ...
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Acorus Calamus
''Acorus calamus'' (also called sweet flag, sway or muskrat root, among many common names) is a species of flowering plant with psychoactive chemicals. It is a tall wetland monocot of the family Acoraceae, in the genus ''Acorus.'' Although used in traditional medicine over centuries to treat digestive disorders and pain, there is no clinical evidence for its safety or efficacy – and ingested calamus may be toxic – leading to its commercial ban in the United States. Description Sweet flag is a herbaceous perennial, tall. Its leaves resembles those of the iris family. Sweet flag consists of tufts of basal leaves that rise from a spreading rhizome. The leaves are erect yellowish-brown, radical, with pink sheathing at their bases, sword-shaped, flat and narrow, tapering into a long, acute point, and have parallel veins. The leaves have smooth edges, which can be wavy or crimped. The sweet flag can be distinguished from iris and other similar plants by the crimpe ...
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Phenylpropanoid
The phenylpropanoids are a diverse family of organic compounds that are synthesized by plants from the amino acids phenylalanine and tyrosine. Their name is derived from the six-carbon, aromatic phenyl group and the three-carbon propene tail of coumaric acid, which is the central intermediate in phenylpropanoid biosynthesis. From 4-coumaroyl-CoA emanates the biosynthesis of myriad natural products including lignols (precursors to lignin and lignocellulose), flavonoids, isoflavonoids, coumarins, aurones, stilbenes, catechin, and phenylpropanoids. The coumaroyl component is produced from cinnamic acid. Phenylpropanoids are found throughout the plant kingdom, where they serve as essential components of a number of structural polymers, provide protection from ultraviolet light, defend against herbivores and pathogens, and also mediate plant-pollinator interactions as floral pigments and scent compounds. Hydroxycinnamic acids Phenylalanine is first converted to cinnamic aci ...
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Acorus
''Acorus'' is a genus of monocot flowering plants. This genus was once placed within the family Araceae (aroids), but more recent classifications place it in its own family Acoraceae and order Acorales, of which it is the sole genus of the oldest surviving line of monocots. Some older studies indicated that it was placed in a lineage (the order Alismatales), that also includes aroids (Araceae), Tofieldiaceae, and several families of aquatic monocots (e.g., Alismataceae, Posidoniaceae). However, modern phylogenetic studies demonstrate that ''Acorus'' is sister to all other monocots. Common names include calamus and sweet flag. The genus is native to North America and northern and eastern Asia, and naturalised in southern Asia and Europe from ancient cultivation. The known wild populations are diploid except for some tetraploids in eastern Asia, while the cultivated plants are sterile triploids, probably of hybrid origin between the diploid and tetraploid forms. Characteristics ...
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2,4,5-Trimethoxypropiophenone
2,4,5-Trimethoxypropiophenone is a natural phenylpropanoid and precursor in the synthesis of α-asarone. Natural occurrence 2,4,5-Trimethoxypropiophenone is a component of several plant species' essential oils. The chemical has been identified in ''Piper marginatum ''Piper marginatum'', the cake bush, Anesi wiwiri, marigold pepper, Ti Bombé in Creole or Hinojo, is a plant species in the genus ''Piper (plant), Piper'' found in moist, shady spots in the Amazon rainforest in Surinam, French Guiana and Brazil. ...'', '' Acorus tatarinowii'', and '' Asarum maximum''. References O-methylated phenylpropanoids Aromatic ketones {{organic-compound-stub ...
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Chemical Compound
A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) containing atoms from more than one chemical element held together by chemical bonds. A molecule consisting of atoms of only one element is therefore not a compound. A compound can be transformed into a different substance by a chemical reaction, which may involve interactions with other substances. In this process, bonds between atoms may be broken and/or new bonds formed. There are four major types of compounds, distinguished by how the constituent atoms are bonded together. Molecular compounds are held together by covalent bonds; ionic compounds are held together by ionic bonds; intermetallic compounds are held together by metallic bonds; coordination complexes are held together by coordinate covalent bonds. Non-stoichiometric compounds form a disputed marginal case. A chemical formula specifies the number of atoms of each element in a compound molecule, using the s ...
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Asarum
''Asarum'' is a genus of plants in the birthwort family Aristolochiaceae, commonly known as wild ginger. ''Asarum'' is the genitive plural of the Latin ''āsa'' (an alternate form of ''āra'') meaning altar or sanctuary. Description ''Asarum'' is a genus of low-growing herbs distributed across the temperate zones of the Northern Hemisphere, with most species in East Asia (China, Japan, and Vietnam) and North America, and one species in Europe. Biogeographically, ''Asarum'' originated in Asia. They have characteristic kidney-shaped leaves, growing from creeping rhizomes, and bear small, axillary, brown or reddish flowers. The plant is called wild ginger because the rhizome tastes and smells similar to ginger root, but the two are not particularly related. The FDA warns against consuming ''Asarum'', as it is nephrotoxic and contains the potent carcinogen aristolochic acid. The birthwort family also contains the genus ''Aristolochia'', known for carcinogens. Wild ginger favor ...
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Isomer
In chemistry, isomers are molecules or polyatomic ions with identical molecular formulae – that is, same number of atoms of each element – but distinct arrangements of atoms in space. Isomerism is existence or possibility of isomers. Isomers do not necessarily share similar chemical or physical properties. Two main forms of isomerism are structural or constitutional isomerism, in which ''bonds'' between the atoms differ; and stereoisomerism or spatial isomerism, in which the bonds are the same but the ''relative positions'' of the atoms differ. Isomeric relationships form a hierarchy. Two chemicals might be the same constitutional isomer, but upon deeper analysis be stereoisomers of each other. Two molecules that are the same stereoisomer as each other might be in different conformational forms or be different isotopologues. The depth of analysis depends on the field of study or the chemical and physical properties of interest. The English word "isomer" () is a back-for ...
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Fragrance Oil
Fragrance oils, also known as aroma oils, aromatic oils, and flavor oils, are blended synthetic aroma compounds or natural essential oils that are diluted with a carrier like propylene glycol, vegetable oil, or mineral oil. To allergic or otherwise sensitive people, synthetic fragrance oils are often less desirable than plant-derived essential oils as components of perfume. Essential oils, widely used in society, emit numerous volatile organic compounds (VOCs). Some of these VOCs are considered as potentially hazardous under federal regulations However, synthetic versions of the same compound as a natural essential oil are usually very comparable. Furthermore, natural oils are in many cases significantly more expensive than their synthetic equivalents. Aromatic oils are used in perfumery, candles, cosmetics, flavoring of food. Some include (out of a very diverse range): * Ylang ylang * Vanilla * Sandalwood * Cedar wood * Mandarin orange * Cinnamon * Lemongrass * Rosehip * Pepperm ...
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Pest (organism)
A pest is any animal or plant harmful to humans or human concerns. The term is particularly used for creatures that damage crops, livestock, and forestry or cause a nuisance to people, especially in their homes. Humans have modified the environment for their own purposes and are intolerant of other creatures occupying the same space when their activities impact adversely on human objectives. Thus, an elephant is unobjectionable in its natural habitat but a pest when it tramples crops. Some animals are disliked because they bite or sting; snake Snakes are elongated, Limbless vertebrate, limbless, carnivore, carnivorous reptiles of the suborder Serpentes . Like all other Squamata, squamates, snakes are ectothermic, amniote vertebrates covered in overlapping Scale (zoology), scales. Ma ...s, wasps, ants, bed bugs, fleas and ticks belong in this category. Others enter the home; these include houseflies, which land on and contaminate food, beetles, which tunnel into the woodwor ...
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Trimethoxyamphetamine
Trimethoxyamphetamines (TMAs) are a family of isomeric psychedelic hallucinogenic drugs. There exist six different TMAs that differ only in the position of the three methoxy groups: TMA, TMA-2, TMA-3, TMA-4, TMA-5, and TMA-6. The TMAs are analogs of the phenethylamine cactus alkaloid mescaline. The TMAs are substituted amphetamines, however, their mechanism of action is more complex than that of the unsubstituted compound ''amphetamine'', probably involving agonist activity on serotonin receptors such as the 5HT2A receptor in addition to the generalised dopamine receptor agonism typical of most amphetamines. This action on serotonergic receptors likely underlie the psychedelic effects of these compounds. It is reported that some TMAs elicit a range of emotions ranging from sadness to empathy and euphoria. TMA was first synthesized by Hey, in 1947. Synthesis data as well as human activity data has been published in the book '' PiHKAL''. The most important TMA compound from a phar ...
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Carcinogen
A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis (the formation of cancer). This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes. Several radioactive substances are considered carcinogens, but their carcinogenic activity is attributed to the radiation, for example gamma rays and alpha particles, which they emit. Common examples of non-radioactive carcinogens are inhaled asbestos, certain dioxins, and tobacco smoke. Although the public generally associates carcinogenicity with synthetic chemicals, it is equally likely to arise from both natural and synthetic substances. Carcinogens are not necessarily immediately toxic; thus, their effect can be insidious. Carcinogens, as mentioned, are agents in the environment capable of contributing to cancer growth. Carcinogens can be categorized into two different types: activation-dependent and activation-independent, and each nature impacts their level ...
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Bitters
Bitters (plural also ''bitters'') is traditionally an alcoholic preparation flavored with botanical matter for a bitter or bittersweet flavor. Originally, numerous longstanding brands of bitters were developed as patent medicines, but now are sold as digestifs, sometimes with herbal properties, and as cocktail flavorings. Since cocktails often contain sour and sweet flavors, bitters are used to engage another primary taste and thereby balance out the drink and make it more complex, giving it a more complete flavor profile. Ingredients The botanical ingredients used historically in preparing bitters have consisted of aromatic herbs, bark, roots, and/or fruit for their flavor and medicinal properties. Some of the more common ingredients are cascarilla, cassia (Chinese cinnamon), gentian, orange peel, and cinchona bark. Most bitters contain both water and alcohol, the latter of which functions as a solvent for botanical extracts as well as a preservative. The alcoholic stre ...
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