Anterior White Commissure
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Anterior White Commissure
The anterior white commissure (ventral white commissure) is a bundle of nerve fibers which cross the midline of the spinal cord just anterior (in front of) to the gray commissure (Rexed lamina X). A delta fibers (Aδ fibers) and C fibers carrying pain sensation in the spinothalamic tract contribute to this commissure, as do fibers of the anterior corticospinal tract, which carry motor signals from the primary motor cortex. Two of the five sensory modalities, pain and temperature, cross sides at the anterior white commissure, reaching the contralateral side about two vertebral levels rostral to their origin. The spinothalamic tract thus decussates very soon after entering the spinal cord, ascending in the spinal cord, contralateral to the side from where it provides (pain and temperature) sensory information. Therefore, a lesion that is caudal to the sensory decussation where the remaining 3/5 modalities decussate (at the superior medulla) will result in contralateral (opposite s ...
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Nerve Fiber
An axon (from Greek ἄξων ''áxōn'', axis), or nerve fiber (or nerve fibre: see spelling differences), is a long, slender projection of a nerve cell, or neuron, in vertebrates, that typically conducts electrical impulses known as action potentials away from the nerve cell body. The function of the axon is to transmit information to different neurons, muscles, and glands. In certain sensory neurons (pseudounipolar neurons), such as those for touch and warmth, the axons are called afferent nerve fibers and the electrical impulse travels along these from the periphery to the cell body and from the cell body to the spinal cord along another branch of the same axon. Axon dysfunction can be the cause of many inherited and acquired neurological disorders that affect both the peripheral and central neurons. Nerve fibers are classed into three typesgroup A nerve fibers, group B nerve fibers, and group C nerve fibers. Groups A and B are myelinated, and group C are unmyelinated. The ...
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Spinal Cord
The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column (backbone). The backbone encloses the central canal of the spinal cord, which contains cerebrospinal fluid. The brain and spinal cord together make up the central nervous system (CNS). In humans, the spinal cord begins at the occipital bone, passing through the foramen magnum and then enters the spinal canal at the beginning of the cervical vertebrae. The spinal cord extends down to between the first and second lumbar vertebrae, where it ends. The enclosing bony vertebral column protects the relatively shorter spinal cord. It is around long in adult men and around long in adult women. The diameter of the spinal cord ranges from in the cervical and lumbar regions to in the thoracic area. The spinal cord functions primarily in the transmission of nerve signals from the motor cortex to the body, ...
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Anatomical Terms Of Location
Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position provides a definition of what is at the front ("anterior"), behind ("posterior") and so on. As part of defining and describing terms, the body is described through the use of anatomical planes and anatomical axes. The meaning of terms that are used can change depending on whether an organism is bipedal or quadrupedal. Additionally, for some animals such as invertebrates, some terms may not have any meaning at all; for example, an animal that is radially symmetrical will have no anterior surface, but can still have a description that a part is close to the middle ("proximal") or further from the middle ("distal"). International organisations have determined vocabularies that are often used as standard vocabularies for subdisciplines of anatom ...
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Gray Commissure
The grey commissure is a thin strip of grey matter that surrounds the central canal of the spinal cord and, along with the anterior white commissure The anterior white commissure (ventral white commissure) is a bundle of nerve fibers which cross the midline of the spinal cord just anterior (in front of) to the gray commissure (Rexed lamina X). A delta fibers (Aδ fibers) and C fibers carryin ..., connects the two halves of the cord. It comprises lamina X in the Rexed classification. External links * Spinal cord {{neuroscience-stub ...
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Rexed Laminae
The Rexed laminae comprise a system of ten layers of grey matter (I–X), identified in the early 1950s by Bror Rexed to label portions of the grey columns of the spinal cord. Similar to Brodmann areas, they are defined by their cellular structure rather than by their location, but the location still remains reasonably consistent. Laminae * Posterior grey column: I–VI ** Lamina I: marginal nucleus of spinal cord or posteromarginal nucleus ** Lamina II: substantia gelatinosa of Rolando ** Laminae III and IV: nucleus proprius ** Lamina V: Neck of the dorsal horn. Neurons within lamina V are mainly involved in processing sensory afferent stimuli from cutaneous, muscle and joint mechanical nociceptors as well as visceral nociceptors. This layer is home to wide dynamic range tract neurons, interneurons and propriospinal neurons. Viscerosomatic pain signal convergence often occurs in this lamina due to the presence of wide dynamic range tract neurons resulting in pain referral. ** Lam ...
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A Delta Fiber
Group A nerve fibers are one of the three classes of nerve fiber as ''generally classified'' by Erlanger and Gasser. The other two classes are the group B nerve fibers, and the group C nerve fibers. Group A are heavily myelinated, group B are moderately myelinated, and group C are unmyelinated. The other classification is a sensory grouping that uses the terms '' type Ia and type Ib'', '' type II'', ''type III'', and ''type IV'', sensory fibers. Types There are four subdivisions of group A nerve fibers: alpha (α) Aα; beta (β) Aβ; , gamma (γ) Aγ, and delta (δ) Aδ. These subdivisions have different amounts of myelination and axon thickness and therefore transmit signals at different speeds. Larger diameter axons and more myelin insulation lead to faster signal propagation. Group A nerves are found in both motor and sensory pathways. Different sensory receptors are innervated by different types of nerve fibers. Proprioceptors are innervated by type Ia, Ib and II s ...
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C Fibers
Group C nerve fibers are one of three classes of nerve fiber in the central nervous system (CNS) and peripheral nervous system (PNS). The C group fibers are unmyelinated and have a small diameter and low conduction velocity, whereas Groups A and B are myelinated. Group C fibers include postganglionic fibers in the autonomic nervous system (ANS), and nerve fibers at the dorsal roots (IV fiber). These fibers carry sensory information. Damage or injury to nerve fibers causes neuropathic pain. Capsaicin activates C fibre vanilloid receptors, giving chili peppers a hot sensation. Structure and anatomy Location C fibers are one class of nerve fiber found in the nerves of the somatic sensory system. They are afferent fibers, conveying input signals from the periphery to the central nervous system. Structure C fibers are unmyelinated unlike most other fibers in the nervous system. This lack of myelination is the cause of their slow conduction velocity, which is on the order of ...
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Spinothalamic Tract
The spinothalamic tract is a part of the anterolateral system or the ventrolateral system, a sensory pathway to the thalamus. From the ventral posterolateral nucleus in the thalamus, sensory information is relayed upward to the somatosensory cortex of the postcentral gyrus. The spinothalamic tract consists of two adjacent pathways: anterior and lateral. The anterior spinothalamic tract carries information about crude touch. The lateral spinothalamic tract conveys pain and temperature. In the spinal cord, the spinothalamic tract has somatotopic arrangement, somatotopic organization. This is the segmental organization of its Neck, cervical, thoracic, lumbar, and Sacrum, sacral components, which is arranged from most medial to most lateral respectively. The pathway crosses over (decussates) at the level of the spinal cord, rather than in the brainstem like the dorsal column-medial lemniscus pathway and lateral corticospinal tract. It is one of the three tracts which make up the an ...
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Anterior Corticospinal Tract
The anterior corticospinal tract (also called the ventral corticospinal tract, "Bundle of Turck", medial corticospinal tract, direct pyramidal tract, or anterior cerebrospinal fasciculus) is a small bundle of descending fibers that connect the cerebral cortex to the spinal cord. Descending tracts are pathways by which motor signals are sent from upper motor neurons in the brain to lower motor neurons which then directly innervate muscle to produce movement. The anterior corticospinal tract is usually small, varying inversely in size with the lateral corticospinal tract, which is the main part of the corticospinal tract. It lies close to the anterior median fissure, and is present only in the upper part of the spinal cord; gradually diminishing in size as it descends, it ends about the middle of the thoracic region. It consists of descending fibers that arise from cells in the motor area of the ipsilateral cerebral hemisphere. The impulse travels from these upper motor neurons (lo ...
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Primary Motor Cortex
The primary motor cortex (Brodmann area 4) is a brain region that in humans is located in the dorsal portion of the frontal lobe. It is the primary region of the motor system and works in association with other motor areas including premotor cortex, the supplementary motor area, posterior parietal cortex, and several subcortical brain regions, to plan and execute voluntary movements. Primary motor cortex is defined anatomically as the region of cortex that contains large neurons known as Betz cells, which, along with other cortical neurons, send long axons down the spinal cord to synapse onto the interneuron circuitry of the spinal cord and also directly onto the alpha motor neurons in the spinal cord which connect to the muscles. At the primary motor cortex, motor representation is orderly arranged (in an inverted fashion) from the toe (at the top of the cerebral hemisphere) to mouth (at the bottom) along a fold in the cortex called the central sulcus. However, some body parts ...
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Sensory Modalities
Stimulus modality, also called sensory modality, is one aspect of a stimulus or what is perceived after a stimulus. For example, the temperature modality is registered after heat or cold stimulate a receptor. Some sensory modalities include: light, sound, temperature, taste, pressure, and smell. The type and location of the sensory receptor activated by the stimulus plays the primary role in coding the sensation. All sensory modalities work together to heighten stimuli sensation when necessary. Multimodal perception Multimodal perception is the ability of the mammalian nervous system to combine all of the different inputs of the sensory nervous system to result in an enhanced detection or identification of a particular stimulus. Combinations of all sensory modalities are done in cases where a single sensory modality results in ambiguous and incomplete result. Integration of all sensory modalities occurs when multimodal neurons receive sensory information which overlaps with di ...
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Sensory Decussation
In neuroanatomy, the sensory decussation or decussation of the lemnisci is a decussation (i.e. crossover) of axons from the gracile nucleus and cuneate nucleus, which are responsible for fine touch, vibration, proprioception and two-point discrimination of the body. The fibres of this decussation are called the internal arcuate fibres and are found at the superior aspect of the closed medulla superior to the motor decussation. It is part of the second neuron in the posterior column–medial lemniscus pathway. Structure At the level of the closed medulla in the posterior white column, two large nuclei namely the gracile nucleus and the cuneate nucleus can be found. The two nuclei receive the impulse from the two ascending tracts: fasciculus gracilis and fasciculus cuneatus. After the two tracts terminate upon these nuclei, the heavily myelinated fibres arise and ascend anteromedially around the periaqueductal gray as internal arcuate fibres. These fibres decussate (cross) ...
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