Allo-Inositol
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Allo-Inositol
''allo''-Inositol is a stereoisomer of inositol Inositol, or more precisely ''myo''-inositol, is a carbocyclic sugar that is abundant in the brain and other mammalian tissues; it mediates cell signal transduction in response to a variety of hormones, neurotransmitters, and growth factors and .... See also * ''cis''-Inositol * D-''chiro''-Inositol * L-''chiro''-Inositol * ''epi''-Inositol * ''muco''-Inositol * ''neo''-Inositol * ''scyllo''-Inositol References Inositol {{alcohol-stub ...
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International Union Of Pure And Applied Chemistry
The International Union of Pure and Applied Chemistry (IUPAC ) is an international federation of National Adhering Organizations working for the advancement of the chemical sciences, especially by developing nomenclature and terminology. It is a member of the International Science Council (ISC). IUPAC is registered in Zürich, Switzerland, and the administrative office, known as the "IUPAC Secretariat", is in Research Triangle Park, North Carolina, United States. This administrative office is headed by IUPAC's executive director, currently Lynn Soby. IUPAC was established in 1919 as the successor of the International Congress of Applied Chemistry for the advancement of chemistry. Its members, the National Adhering Organizations, can be national chemistry societies, national academies of sciences, or other bodies representing chemists. There are fifty-four National Adhering Organizations and three Associate National Adhering Organizations. IUPAC's Inter-divisional Committee on ...
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Royal Society Of Chemistry
The Royal Society of Chemistry (RSC) is a learned society (professional association) in the United Kingdom with the goal of "advancing the chemistry, chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the Royal Institute of Chemistry, the Faraday Society, and the Society for Analytical Chemistry with a new Royal Charter and the dual role of learned society and professional body. At its inception, the Society had a combined membership of 34,000 in the UK and a further 8,000 abroad. The headquarters of the Society are at Burlington House, Piccadilly, London. It also has offices in Thomas Graham House in Cambridge (named after Thomas Graham (chemist), Thomas Graham, the first president of the Chemical Society) where ''RSC Publishing'' is based. The Society has offices in the United States, on the campuses of The University of Pennsylvania and Drexel University, at the University City Science Center in Philadelphia, Pennsylvania, in both Beijing a ...
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Stereoisomer
In stereochemistry, stereoisomerism, or spatial isomerism, is a form of isomerism in which molecules have the same molecular formula and sequence of bonded atoms (constitution), but differ in the three-dimensional orientations of their atoms in space. This contrasts with structural isomers, which share the same molecular formula, but the bond connections or their order differs. By definition, molecules that are stereoisomers of each other represent the same structural isomer. Enantiomers Enantiomers, also known as optical isomers, are two stereoisomers that are related to each other by a reflection: they are mirror images of each other that are non-superposable. Human hands are a macroscopic analog of this. Every stereogenic center in one has the opposite configuration in the other. Two compounds that are enantiomers of each other have the same physical properties, except for the direction in which they rotate polarized light and how they interact with different optical isom ...
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Inositol
Inositol, or more precisely ''myo''-inositol, is a carbocyclic sugar that is abundant in the brain and other mammalian tissues; it mediates cell signal transduction in response to a variety of hormones, neurotransmitters, and growth factors and participates in osmoregulation. It is a sugar alcohol with half the sweetness of sucrose (table sugar). It is made naturally in the human body from glucose. A human kidney makes about two grams per day. Other tissues synthesize it too, and the highest concentration is in the brain, where it plays an important role by making other neurotransmitters and some steroid hormones bind to their receptors. Inositol is promoted as a dietary supplement in the management of polycystic ovary syndrome (PCOS). However, there is only evidence of very low quality for its efficacy in increasing fertility for IVF in women with PCOS. Overview ''myo''-Inositol plays an important role as the structural basis for a number of secondary messengers in eukaryotic ...
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D-chiro-Inositol
1D-''chiro''-Inositol (formerly D-''chiro''-inositol, commonly abbreviated DCI) is a member of a family of related substances often referred to collectively as "inositol", although that term encompasses several isomers of questionable biological relevance, including 1L-chiro-Inositol, 1L-''chiro''-inositol. ''myo''-Inositol is converted into DCI by an insulin dependent NAD/NADH epimerase enzyme. It is known to be an important secondary messenger in insulin signal transduction. DCI accelerates the dephosphorylation of glycogen synthase and pyruvate dehydrogenase, rate limiting enzymes of non-oxidative and oxidative glucose disposal. DCI may act to bypass defective normal epimerization of ''myo''-inositol to DCI associated with insulin resistance and at least partially restore insulin sensitivity and glucose disposal. One pilot study found males taking it had increased androgens and reduced estrogen. References

{{DEFAULTSORT:Inositol, D-chiro- Inositol ...
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L-chiro-Inositol
1L-''chiro''-Inositol (L-''chiro''-Inositol) is one of the isomers of inositol Inositol, or more precisely ''myo''-inositol, is a carbocyclic sugar that is abundant in the brain and other mammalian tissues; it mediates cell signal transduction in response to a variety of hormones, neurotransmitters, and growth factors and .... See also * ''allo''-Inositol * ''cis''-Inositol * 1D-''chiro''-Inositol * ''epi''-Inositol * ''muco''-Inositol * ''neo''-Inositol * ''scyllo''-Inositol References Inositol {{alcohol-stub ...
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Epi-Inositol
''Epi''-Inositol is one of the stereoisomers of inositol. Use in medicine Epi-inositol has been found to regulate Yeast Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are estimated to constitut ... INO1 Gene Encoding ( Inositol-1-P synthase) in animals. During the study with Epi-Inositol, Yeast INO1-expression was measured in northern blots. See also * ''allo''-Inositol * ''cis''-Inositol * D-''chiro''-Inositol * L-''chiro''-Inositol * ''muco''-Inositol * ''neo''-Inositol * ''scyllo''-Inositol References Inositol {{alcohol-stub ...
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Neo-Inositol
''neo''-Inositol is one of the stereoisomers of inositol Inositol, or more precisely ''myo''-inositol, is a carbocyclic sugar that is abundant in the brain and other mammalian tissues; it mediates cell signal transduction in response to a variety of hormones, neurotransmitters, and growth factors and .... It is one of the nine isomeric forms of cyclohexanehexol; a group of small and chemically very stable polar molecules that have versatile properties. This stereoisomer is naturally occurring, but only in small amounts. It is also known as (1s,2R,3R,4s,5S,6S)-cyclohexane-1,2,3,4,5,6-hexol or 1,2,3/4,5,6-cyclohexanehexol in the IUPAC naming system. See also * ''allo''-Inositol * ''cis''-Inositol * D-''chiro''-Inositol * L-''chiro''-Inositol * ''epi''-Inositol * ''muco''-Inositol * ''scyllo''-Inositol References Inositol {{alcohol-stub ...
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Scyllo-Inositol
''scyllo''-Inositol is one of the stereoisomers of inositol. It is also known as scyllitol, cocositol, quercinitol, and 1,3,5/2,4,6-hexahydroxycyclohexane. ''scyllo''-Inositol is a naturally occurring plant sugar alcohol found most abundantly in the coconut palm. Biological effects Researchers at the University of Toronto have found that ''scyllo''-inositol can block the development of amyloid-beta (Aβ) plaques in the brains of transgenic mice. ''scyllo''-Inositol also reversed memory deficits, reduced the formation of Aβ plaques, and alleviated other symptoms that are associated with the accumulation of Aβ proteins in these mice. Researchers at the Harvard Medical School-affiliated McLean Hospital identified that chronic users of anabolic steroids had statistically significantly lower levels of brain scyllo-inositol levels as compared to non-users. Clinical evaluation ''scyllo''-Inositol is under investigation by Transition Therapeutics as a disease-modifying therapy fo ...
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