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Zydus
Zydus Lifesciences Limited, formerly known as Cadila Healthcare Limited, is an Indian multinational pharmaceutical company headquartered in Ahmedabad, which is primarily engaged in the manufacture of generic drugs. It ranked 100th in the Fortune India 500 list in 2020. History Cadila was founded in 1952 by Ramanbhai Patel (1925–2001), formerly a lecturer in the L.M. College of Pharmacy, and his business partner Indravadan Modi. It evolved over the next four decades into an established pharmaceutical company. In 1995 the Patel and Modi families split; the Modi family's share was moved into a new company called Cadila Pharmaceuticals Ltd., and Cadila Healthcare Ltd became the Patel family's holding company. Cadila Healthcare had its initial public offering on the Bombay Stock Exchange in 2000 as stock code 532321. In 2015 the company acquired another Indian pharmaceutical company called German Remedies. On 25 June 2007, the company acquired Química e Farmacêutica Nikkho ...
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ZyCoV-D
ZyCoV-D is a DNA vaccine, DNA plasmid-based COVID-19 vaccine developed by Indian pharmaceutical company Cadila Healthcare, with support from the Biotechnology Industry Research Assistance Council. It is emergency use authorisation, approved for emergency use in India. Technology The vaccine contains a DNA plasmid Vectors in gene therapy#Non-viral methods, vector that carries the gene encoding the coronavirus spike protein, spike protein of SARS-CoV-2. As with other DNA vaccines, the recipient's cells then produce the spike protein, eliciting a protective immune response. The plasmid also contains DNA methylation, unmethylated CpG site, CpG motifs to enhance its immunostimulatory properties. The plasmid is produced using Escherichia coli, ''E. coli'' cells. The vaccine is given as an intradermal injection using a spring-powered jet injector. This is because successful transfection of DNA vaccines requires traveling across both the Cell membrane, cell plasma membrane and ...
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