Yuk Ming Dennis Lo
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Yuk Ming Dennis Lo
Dennis Yuk Ming Lo (, born 12 October 1963) is a Hong Kong molecular biologist, and an important contributor to the development of non-invasive prenatal testing. He is the current Associate Dean (Research) and Li Ka Shing Professor of Medicine at the Chinese University of Hong Kong (CUHK), as well as the head of the Department of Chemical Pathology of CUHK and the director of the Li Ka Shing Institute of Health Sciences. His research focuses on the detection of cell-free fetal DNA in blood plasma. Early life and education Lo was born in Hong Kong in 1963. His mother taught music and his father, Wai-hoi Lo, who immigrated from Chaozhou to Hong Kong in 1946, was a psychiatrist and the former head of Castle Peak Hospital. He also has a younger brother. Lo attended St Joseph's College for primary and secondary schools. After secondary school, he was accepted by Stanford University for electrical engineering and by the University of Hong Kong and University of Cam ...
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Lu (surname 卢)
Lu, Lü, or LU may refer to: Arts and entertainment * Lu (music), Tibetan folk music * Lu (duo), a Mexican band ** Lu (album), ''Lu'' (album) * Character from Mike, Lu & Og * Lupe Fiasco or Lu (born 1982), American musician * Lebor na hUidre, a manuscript containing many Irish fictional stories commonly abbreviated LU *Lu (novel), 2018 novel by Jason Reynolds Chinese surnames *Lu (surname), including: **Lu (surname 卢), the 52nd commonest **Lu (surname 陆), the 61st commonest **Lu (surname 鲁), the 115th commonest **Lu (surname 路), the 116th commonest **Lu (surname 芦), the 140th commonest **Lu (surname 禄) **Lu (surname 逯) **Lu (surname 鹿) *Lü (surname), 吕, the 47th commonest Places Asia *Lu (state) of ancient China, in today's Shandong Province *Lü (state), an ancient Chinese state *Lu Commandery, of ancient China *Lù, a circuit (administrative division) in China *Lu, Iran, Isfahan Province *Lu County, Sichuan, China *La Union, Philippines, from its initials ...
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Medicine
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, o ...
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Clinical Chemistry (journal)
''Clinical Chemistry'' is a peer-reviewed medical journal covering the field of clinical chemistry. It is the official journal of the American Association for Clinical Chemistry. The journal was first published in 1955 on a bi-monthly basis "to raise the level at which chemistry is practiced in the clinical laboratory"; monthly publication commenced in 1964.Rej, R. Clin Chem 50:2415-58 (2004) The editor-in-chief is Nader Rifai (Harvard Medical School). Abstracting and indexing The journal is abstracted and indexed in PubMed/MEDLINE and the Science Citation Index. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 8.327. References External links * {{Official website, http://intl.clinc ...
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American Journal Of Obstetrics And Gynecology
The ''American Journal of Obstetrics and Gynecology'' (AJOG) is a peer reviewed journal of obstetrics and gynecology. It is popularly called the "Gray Journal". Since 1920, AJOG has continued the American Journal of Obstetrics and Diseases of Women and Children, which began publishing in 1868. AJOG has been Medline-indexed since 1965. The current editors-in-chief are Catherine Bradley, MD, MSCE & Roberto Romero, MD, DMedSci. It is the official publication of the following societies and associations: * American Gynecological and Obstetrical Society * Association of Professors of Gynecology and Obstetrics * Central Association of Obstetricians and Gynecologists * Pacific Coast Obstetrical and Gynecological Society * Society of Gynecologic Surgeons * Society for Maternal-Fetal Medicine The Society for Maternal-Fetal Medicine was established in 1977 and is a not-for-profit organization of over 5,000 members that are dedicated to improving maternal and child outcomes. The organizatio ...
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Chaozhou
Chaozhou (), alternatively Chiuchow, Chaochow or Teochew, is a city in the eastern Guangdong province of China. It borders Shantou to the south, Jieyang to the southwest, Meizhou to the northwest, the province of Fujian to the east, and the South China Sea to the southeast. It is administered as a prefecture-level city with a jurisdiction area of and a total population of 2,568,387. Its built-up (or metro) area encompassing most of Shantou and Jieyang cities was home to 12,543,024 inhabitants on 13 local administrative areas. Along with Shantou and Jieyang, Chaozhou is a cultural center of the Chaoshan region. History In 214 BC, Chaozhou was an undeveloped part of Nanhai Commandery () of the Qin Dynasty. In 331 during the Eastern Jin Dynasty, Haiyang () was established as a part of Dongguan Commandery (). The Dongguan Commandery was renamed Yi'an Commandery () in 413. The commandery became a prefecture in 590 during the early Sui Dynasty, first as Xun Prefecture (), then as ...
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Cell-free Fetal DNA
Cell-free fetal DNA (cffDNA) is fetal DNA that circulates freely in the maternal blood. Maternal blood is sampled by venipuncture. Analysis of cffDNA is a method of non-invasive prenatal diagnosis frequently ordered for pregnant women of advanced maternal age. Two hours after delivery, cffDNA is no longer detectable in maternal blood. Background cffDNA originates from placental trophoblasts. Fetal DNA is fragmented when placental microparticles are shed into the maternal blood circulation. cffDNA fragments are approximately 200 base pairs (bp) in length. They are significantly smaller than maternal DNA fragments. The difference in size allows cffDNA to be distinguished from maternal DNA fragments. Approximately 11 to 13.4 percent of the cell-free DNA in maternal blood is of fetal origin. The amount varies widely from one pregnant woman to another. cffDNA is present after five to seven weeks gestation. The amount of cffDNA increases as the pregnancy progresses. The quantity of ...
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Clinical Chemistry
Clinical chemistry (also known as chemical pathology, clinical biochemistry or medical biochemistry) is the area of chemistry that is generally concerned with analysis of bodily fluids for diagnostic and therapeutic purposes. It is an applied form of biochemistry (not to be confused with medicinal chemistry, which involves basic research for drug development). The discipline originated in the late 19th century with the use of simple chemical reaction tests for various components of blood and urine. In the many decades since, other techniques have been applied as science and technology have advanced, including the use and measurement of enzyme activities, spectrophotometry, electrophoresis, and immunoassay. There are now many blood tests and clinical urine tests with extensive diagnostic capabilities. Most current laboratories are now highly automated to accommodate the high workload typical of a hospital laboratory. Tests performed are closely monitored and quality controll ...
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Li Ka Shing
Sir Ka-shing Li (; born 13 June 1928) is a Hong Kong billionaire business magnate, investor, and philanthropist. As of June 2019, Li is the 31st richest person in the world, with an estimated net wealth of US$33.4 billion. He is the senior advisor for CK Hutchison Holdings and CK Asset Holdings, after he retired from the Chairman of the Board in May 2018; through it, he is the world's leading port investor, developer, and operator of the largest health and beauty retailer in Asia and Europe. Forbes magazine released its Hong Kong fortune league chart in February 2021, which showed that Li Ka-shing had reclaimed his prime position as Hong Kong's richest person, with his net assets topping US$35.40 billion. Li is one of the most influential entrepreneurs in Asia, presiding over a business empire with a diverse portfolio of businesses from a wide array of industries, including transportation, real estate, financial services, retail, and energy and utilities. His conglomerate comp ...
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Dean (education)
Dean is a title employed in academic administrations such as colleges or universities for a person with significant authority over a specific academic unit, over a specific area of concern, or both. In the United States and Canada, deans are usually the head of each constituent college and school that make up a university. Deans are common in private preparatory schools, and occasionally found in middle schools and high schools as well. Origin A "dean" (Latin: ''decanus'') was originally the head of a group of ten soldiers or monks. Eventually an ecclesiastical dean became the head of a group of canons or other religious groups. When the universities grew out of the cathedral schools and monastic schools, the title of dean was used for officials with various administrative duties. Use Bulgaria and Romania In Bulgarian and Romanian universities, a dean is the head of a faculty, which may include several academic departments. Every faculty unit of university or academy. The ...
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Non Invasive Prenatal Testing
Noninvasive prenatal testing (NIPT) is a method used to determine the risk for the fetus being born with certain chromosomal abnormalities, such as trisomy 21, trisomy 18 and trisomy 13. This testing analyzes small DNA fragments that circulate in the blood of a pregnant woman. Unlike most DNA found in the nucleus of a cell, these fragments are not found within the cells, instead they are free-floating, and so are called cell free fetal DNA (cffDNA). These fragments usually contain less than 200 DNA building blocks (base pairs) and arise when cells die, and their contents, including DNA, are released into the bloodstream. cffDNA derives from placental cells and is usually identical to fetal DNA. Analysis of cffDNA from placenta provides the opportunity for early detection of certain chromosomal abnormalities without harming the fetus. Background The use of ultrasound and biochemical markers to detect aneuploidies is usually done in the first and / or second trimester of pregnancy. ...
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Molecular Biologist
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ...
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Hong Kong
Hong Kong ( (US) or (UK); , ), officially the Hong Kong Special Administrative Region of the People's Republic of China ( abbr. Hong Kong SAR or HKSAR), is a city and special administrative region of China on the eastern Pearl River Delta in South China. With 7.5 million residents of various nationalities in a territory, Hong Kong is one of the most densely populated places in the world. Hong Kong is also a major global financial centre and one of the most developed cities in the world. Hong Kong was established as a colony of the British Empire after the Qing Empire ceded Hong Kong Island from Xin'an County at the end of the First Opium War in 1841 then again in 1842.. The colony expanded to the Kowloon Peninsula in 1860 after the Second Opium War and was further extended when Britain obtained a 99-year lease of the New Territories in 1898... British Hong Kong was occupied by Imperial Japan from 1941 to 1945 during World War II; British administration resume ...
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