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Yimon Aye
Yimon Aye ( my, ရည်မွန်အေး; born 12 July 1980 in Burma) is an American chemist and molecular biologist. Currently she is an associate professor of chemistry at EPFL. Career Aye spent her early life in Burma. She completed her undergraduate studies in chemistry at the University of Oxford and obtained her master's degree in 2004. She joined Harvard University to study synthetic organic chemistry with David A. Evans, achieving her PhD in 2009. She then moved to Massachusetts Institute of Technology as a Damon Runyon Cancer Research Foundation fellow to work with JoAnne Stubbe. There she performed research into the regulatory mechanisms of ribonucleotide reductase. In 2012, she started as an assistant professor at Cornell University, where she began her work on redox-dependent cell signaling and genome maintenance pathways. During this time, she developed REX technologies, new methods to facilitate the study of unconventional electrophile-regulated stress s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
US-American
People from the United States of America are known as and refer to themselves as Americans. Different languages use different terms for citizens of the United States. All forms of English refer to US citizens as Americans, a term deriving from the United States of America, the country's official name. In the English context, it came to refer to inhabitants of British America, and then the United States. However, there is some linguistic ambiguity over this use due to the other senses of the word ''American'', which can also refer to people from the Americas in general. Other languages, including Japanese, and Russian, use cognates of American to refer to people from the United States, while others, like French, or particularly Spanish and Portuguese, primarily use terms derived from United States. There are various other local and colloquial names for Americans. The name America probably came from the Italian navigator Amerigo Vespucci. Development of the term ''American'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemist
A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe the properties they study in terms of quantities, with detail on the level of molecules and their component atoms. Chemists carefully measure substance proportions, chemical reaction rates, and other chemical properties. In Commonwealth English, pharmacists are often called chemists. Chemists use their knowledge to learn the composition and properties of unfamiliar substances, as well as to reproduce and synthesize large quantities of useful naturally occurring substances and create new artificial substances and useful processes. Chemists may specialize in any number of subdisciplines of chemistry. Materials scientists and metallurgists share much of the same education and skills with chemists. The work of chemists is often related to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
21st-century American Chemists
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius ( AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman em ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academic Staff Of The École Polytechnique Fédérale De Lausanne
An academy ( Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, '' Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alumni Of The University Of Oxford
Alumni (singular: alumnus (masculine) or alumna (feminine)) are former students of a school, college, or university who have either attended or graduated in some fashion from the institution. The feminine plural alumnae is sometimes used for groups of women. The word is Latin and means "one who is being (or has been) nourished". The term is not synonymous with "graduate"; one can be an alumnus without graduating (Burt Reynolds, alumnus but not graduate of Florida State, is an example). The term is sometimes used to refer to a former employee or member of an organization, contributor, or inmate. Etymology The Latin noun ''alumnus'' means "foster son" or "pupil". It is derived from PIE ''*h₂el-'' (grow, nourish), and it is a variant of the Latin verb ''alere'' "to nourish".Merriam-Webster: alumnus .. Separate, but from the s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cornell University Faculty
Cornell University is a Private Ivy League university, private Statutory college, statutory Land-grant university, land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to teach and make contributions in all fields of knowledge—from the classics to the sciences, and from the theoretical to the applied. These ideals, unconventional for the time, are captured in Cornell's founding principle, a popular 1868 quotation from founder Ezra Cornell: "I would found an institution where any person can find instruction in any study." Cornell is ranked among the top global universities. The university is organized into seven Undergraduate education, undergraduate colleges and seven graduate school, graduate divisions at its main Ithaca campus, with each college and division defining its specific admission standards and academic programs in near autonomy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myanmar Navy
The Myanmar Navy ( my, တပ်မတော် (ရေ); ) is the naval warfare branch of the armed forces of Myanmar. With 24,000 personnel on duty, the navy operates more than 150 vessels. Prior to 1988, the navy was small, and its role in counter-insurgency operations was smaller than those of the army and the air force. The navy has since been expanded to take on a more active role in defense of Myanmar's territorial waters. History Pre-independence The naval arm of the Royal Armed Forces consisted mainly of shallow draft river boats. Its primary missions were to control the Irrawaddy River, and to protect the ships carrying the army to the front. The major war boats carried up to 30 musketeers and were armed with 6- or 12-pounder cannon.Lieberman, pp. 164–167 By the mid-18th century, the navy had acquired a few seafaring ships, manned by European and foreign sailors, that were used to transport the troops in Siamese and Arakanese campaigns. The Arakanese and the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genome Instability
Genome instability (also genetic instability or genomic instability) refers to a high frequency of mutations within the genome of a cellular lineage. These mutations can include changes in nucleic acid sequences, chromosomal rearrangements or aneuploidy. Genome instability does occur in bacteria. In multicellular organisms genome instability is central to carcinogenesis, and in humans it is also a factor in some neurodegenerative diseases such as amyotrophic lateral sclerosis or the neuromuscular disease myotonic dystrophy. The sources of genome instability have only recently begun to be elucidated. A high frequency of externally caused DNA damage can be one source of genome instability since DNA damage can cause inaccurate translesion DNA synthesis past the damage or errors in repair, leading to mutation. Another source of genome instability may be epigenetic or mutational reductions in expression of DNA repair genes. Because endogenous (metabolically-caused) DNA damage is very fr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Signaling
In biology, cell signaling (cell signalling in British English) or cell communication is the ability of a cell to receive, process, and transmit signals with its environment and with itself. Cell signaling is a fundamental property of all cellular life in prokaryotes and eukaryotes. Signals that originate from outside a cell (or extracellular signals) can be physical agents like mechanical pressure, voltage, temperature, light, or chemical signals (e.g., small molecules, peptides, or gas). Cell signaling can occur over short or long distances, and as a result can be classified as autocrine, juxtacrine, intracrine, paracrine, or endocrine. Signaling molecules can be synthesized from various biosynthetic pathways and released through passive or active transports, or even from cell damage. Receptors play a key role in cell signaling as they are able to detect chemical signals or physical stimuli. Receptors are generally proteins located on the cell surface or within the interio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cornell University
Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to teach and make contributions in all fields of knowledge—from the classics to the sciences, and from the theoretical to the applied. These ideals, unconventional for the time, are captured in Cornell's founding principle, a popular 1868 quotation from founder Ezra Cornell: "I would found an institution where any person can find instruction in any study." Cornell is ranked among the top global universities. The university is organized into seven undergraduate colleges and seven graduate divisions at its main Ithaca campus, with each college and division defining its specific admission standards and academic programs in near autonomy. The university also administers three satellite campuses, two in New York City and one in Education City, Qatar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ribonucleotide Reductase
Ribonucleotide reductase (RNR), also known as ribonucleoside diphosphate reductase (rNDP), is an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides. It catalyzes this formation by removing the 2'-hydroxyl group of the ribose ring of nucleoside diphosphates. This reduction produces deoxyribonucleotides. Deoxyribonucleotides in turn are used in the synthesis of DNA. The reaction catalyzed by RNR is strictly conserved in all living organisms. Furthermore, RNR plays a critical role in regulating the total rate of DNA synthesis so that DNA to cell mass is maintained at a constant ratio during cell division and DNA repair. A somewhat unusual feature of the RNR enzyme is that it catalyzes a reaction that proceeds via a free radical mechanism of action. The substrates for RNR are ADP, GDP, CDP and UDP. dTDP (deoxythymidine diphosphate) is synthesized by another enzyme ( thymidylate kinase) from dTMP (deoxythymidine monophosphate). Structure Ribonucleoti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Damon Runyon Cancer Research Foundation
The Damon Runyon Cancer Research Foundation (Damon Runyon) is an American not-for-profit cancer research organization focused on "discovering the talent to discover the cure". The organization states that its goals are to: "identify the best and brightest early career scientists in cancer research, accelerate the translation of scientific discoveries into new diagnostic tools and treatments, and to enable risk-taking on bold new ideas". The organization was founded in 1946 by media personality Walter Winchell in New York City, New York, under the name Damon Runyon Cancer Memorial Fund in memory of his colleague and friend Damon Runyon, a newspaperman and author. History Almost immediately after Runyon's passing on December 10, 1946, Winchell went on the air and asked his audience for contributions to cancer research: Mr. and Mrs. United States! A very dear friend of mine a great newspaperman, a great writer, and a very great guy Damon Runyon, was killed this week by Americ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
