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Xenotransfusion
Xenotransfusion (from Greek '' xenos-'' ''strange'' or ''foreign''), a form of xenotransplantation, was initially defined as the transfer of blood from one species into the veins of another. In most cases, it is a transfer of blood between a non-human animal and a human. However, further experimentation has been done between various non-human animal species. This procedure can be performed without affecting the health of the donor, as only about 10% of their blood volume is used each time. Utilizing the unlimited blood supply from animal sources eliminates the risk of transmitting infectious diseases between humans. In 1658, Dom Robert des Gabets, a French monk, introduced the idea of xenotransfusion at a scientific society meeting. This society later afforded the French Academy of Sciences. Currently there are not any laws prohibiting the practice of xenotransfusion, but some ethical issues have been identified by the Ethics Committee of the International Xenotransplantation Asso ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jean-Baptiste Denys
Jean-Baptiste Denys (1643 – 3 October 1704) was a French physician notable for having performed the first fully documented human blood transfusion, a xenotransfusion. He studied in Montpellier and was the personal physician to King Louis XIV. Early life Jean Baptiste Denys was born in the 1630s, although his birth had gone unnoticed and undocumented. He was born in a family of modest means, in fact, his father was an artisan who specialized in water pumps, which was seeing an increase in popularity with new elaborate systems being introduced. The passion of Denys towards Medicine was also induced by his medical condition, in fact, he suffered from Asthma. Education Despite his family's humble origins, he obtained a bachelor in theology at the College des Grassins and a medical degree at the Faculty of Medicine in Montpellier, when barely thirty. Denys’ ambition drew him to attempt a career in Paris, however, the bad reputation and its location made him an outside ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Richard Lower (physician)
Richard Lower ( – 17 January 1691) was an English physician who heavily influenced the development of medical science. He is most remembered for his pioneering work on blood transfusion and the function of the cardiopulmonary system, which he described in his book '' Tractatus de Corde''. Life Lower was born in St Tudy, Cornwall, and studied at Westminster School, where he met John Locke, as well as Christ Church, Oxford, where he met Thomas Willis. He followed Willis to London, where he carried out anatomical research, some in partnership with Robert Hooke. His major work, ''Tractatus de Corde'' (1669), was concerned with the workings of the heart and lungs. Lower also experimented with blood transfusion. Lower formed part of an informal research team, performing laboratory experiments at the University of Oxford during the Interregnum. He was a pioneer of experimental physiology. Lower was a medical student under Willis (Professor of Natural Philosophy from 1660 to 1675), ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Xenotransplantation
Xenotransplantation (''xenos-'' from the Greek meaning "foreign" or strange), or heterologous transplant, is the transplantation of living cells, tissues or organs from one species to another. Such cells, tissues or organs are called xenografts or xenotransplants. It is contrasted with allotransplantation (from other individual of same species), syngeneic transplantation or isotransplantation (grafts transplanted between two genetically identical individuals of the same species) and autotransplantation (from one part of the body to another in the same person). Xenotransplantation of human tumor cells into immunocompromised mice is a research technique frequently used in pre-clinical oncology research. Human xenotransplantation offers a potential treatment for end-stage organ failure, a significant health problem in parts of the industrialized world. It also raises many novel medical, legal and ethical issues. A continuing concern is that many animals, such as pigs, have a s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Xenotransplantation
Xenotransplantation (''xenos-'' from the Greek meaning "foreign" or strange), or heterologous transplant, is the transplantation of living cells, tissues or organs from one species to another. Such cells, tissues or organs are called xenografts or xenotransplants. It is contrasted with allotransplantation (from other individual of same species), syngeneic transplantation or isotransplantation (grafts transplanted between two genetically identical individuals of the same species) and autotransplantation (from one part of the body to another in the same person). Xenotransplantation of human tumor cells into immunocompromised mice is a research technique frequently used in pre-clinical oncology research. Human xenotransplantation offers a potential treatment for end-stage organ failure, a significant health problem in parts of the industrialized world. It also raises many novel medical, legal and ethical issues. A continuing concern is that many animals, such as pigs, have a s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Xenos (Greek)
''Xenos'' (; ) is a word used in the Greek language from Homer onwards. The most standard definition is "stranger". However, the word itself can be interpreted to mean different things based upon context, author and period of writing/speaking, signifying such divergent concepts as "enemy" or "stranger", a particular hostile interpretation, all the way to "guest friend"' one of the most hallowed concepts in the cultural rules of Greek hospitality. Meanings ''Xenos'' can be translated both to foreigner (in the sense of a person from another Greek state) and to a foreigner or traveler brought into a relationship of long distance friendship. ''Xenos'' can also be used simply to assert that someone is not a member of your community, that is simply foreigner and with no implication of reciprocity or relationship. ''Xenos'' generally refers to the variety of what a particular individual can be, specifically guest, host, stranger, friend, and, as previously mentioned, foreigner. The a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sus Scrofa Domesticus
The pig (''Sus domesticus''), often called swine, hog, or domestic pig when distinguishing from other members of the genus '' Sus'', is an omnivorous, domesticated, even-toed, hoofed mammal. It is variously considered a subspecies of ''Sus scrofa'' (the wild boar or Eurasian boar) or a distinct species. The pig's head-plus-body length ranges from , and adult pigs typically weigh between , with well-fed individuals even exceeding this range. The size and weight of hogs largely depends on their breed. Compared to other artiodactyls, a pig's head is relatively long and pointed. Most even-toed ungulates are herbivorous, but pigs are omnivores, like their wild relative. Pigs grunt and make snorting sounds. When used as livestock, pigs are farmed primarily for the production of meat, called pork. A group of pigs is called a ''passel'', a ''team'', or a ''sounder''. The animal's bones, hide, and bristles are also used in products. Pigs, especially miniature breeds, are kept as pets ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organ Transplantation
Organ transplantation is a medical procedure in which an organ (anatomy), organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The donor and recipient may be at the same location, or organs may be transported from a Organ donation, donor site to another location. Organ (anatomy), Organs and/or Tissue (biology), tissues that are transplanted within the same person's body are called autografts. Transplants that are recently performed between two subjects of the same species are called allografts. Allografts can either be from a living or cadaveric source. Organs that have been successfully transplanted include the Heart transplantation, heart, Kidney transplantation, kidneys, Liver transplantation, liver, Lung transplantation, lungs, Pancreas transplantation, pancreas, Intestinal transplant, intestine, Thymus transplantation, thymus and uterus transplantation, uterus. Tissues include Bone grafting, bones, tendons (both referr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transfusion Medicine
Transfusion medicine (or transfusiology) is the branch of medicine that encompasses all aspects of the transfusion of blood and blood components including aspects related to hemovigilance. It includes issues of blood donation, immunohematology and other laboratory testing for transfusion-transmitted diseases, management and monitoring of clinical transfusion practices, patient blood management, therapeutic apheresis, stem cell collections, cellular therapy, and coagulation. Laboratory management and understanding of state and federal regulations related to blood products are also a large part of the field. Overview In most countries, immunohematology and transfusion medicine specialists provide expert opinion on massive transfusions, difficult/incompatible transfusions and rational use of specialised blood product therapy like irradiated blood/ leukodepleted/washed blood products. The blood donor center is the facility that collects blood components from screened blood dono ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Animal Physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical and physical functions in a living system. According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. ''Physiological state'' is the condition of normal function. In contrast, ''pathological state'' refers to abnormal conditions, including human diseases. The Nobel Prize in Physiology or Medicine is awarded by the Royal Swedish Academy of Sciences for exceptional scientific achievements in physiology related to the field of medicine. Foundations Cells Although there are differences ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Slate (magazine)
''Slate'' is an online magazine that covers current affairs, politics, and culture in the United States. It was created in 1996 by former '' New Republic'' editor Michael Kinsley, initially under the ownership of Microsoft as part of MSN. In 2004, it was purchased by The Washington Post Company (later renamed the Graham Holdings Company), and since 2008 has been managed by The Slate Group, an online publishing entity created by Graham Holdings. ''Slate'' is based in New York City, with an additional office in Washington, D.C. ''Slate'', which is updated throughout the day, covers politics, arts and culture, sports, and news. According to its former editor-in-chief Julia Turner, the magazine is "not fundamentally a breaking news source", but rather aimed at helping readers to "analyze and understand and interpret the world" with witty and entertaining writing. As of mid-2015, it publishes about 1,500 stories per month. A French version, ''slate.fr'', was launched in February 20 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transplant Rejection
Transplant rejection occurs when Organ transplant, transplanted tissue is rejected by the recipient's immune system, which destroys the transplanted tissue. Transplant rejection can be lessened by determining the molecular similitude between donor and recipient and by use of immunosuppressant drugs after transplant. Types of transplant rejection Transplant rejection can be classified into three types: hyperacute, acute, and chronic. These types are differentiated by how quickly the recipient's immune system is activated and the specific aspect or aspects of immunity involved. Hyperacute rejection Hyperacute rejection is a form of rejection that manifests itself in the minutes to hours following transplantation. It is caused by the presence of pre-existing Antibody, antibodies in the recipient that recognize antigens in the donor organ. These antigens are located on the endothelial lining of blood vessels within the transplanted organ and, once antibodies bind, will lead to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Donation
A blood donation occurs when a person voluntarily has blood drawn and used for blood transfusion, transfusions and/or made into biopharmaceutical medications by a process called Blood fractionation, fractionation (separation of whole blood components). Donation may be of whole blood, or of specific components directly (apheresis). Blood banks often participate in the collection process as well as the procedures that follow it. Today in the developed world, most blood donors are unpaid volunteers who donate blood for a community supply. In some countries, established supplies are limited and donors usually give blood when family or friends need a transfusion (directed donation). Many donors donate for several reasons, such as a form of charity, general awareness regarding the demand for blood, increased confidence in oneself, helping a personal friend or relative, and social pressure. Despite the many reasons that people donate, not enough potential donors actively donate. Ho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
