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XLfit
XLfit is a Microsoft Excel add-in that can perform regression analysis, curve fitting, and statistical analysis. It is approved by the UK National Physical Laboratory and the US National Institute of Standards and Technology XLfit can generate 2D and 3D graphs and analyze data sets. XLfit can also analyse the statistical data. It includes over seventy linear and non-linear curve fitting models. Predefined categories include: * Exponential/ Log, Power Series, Sigmoidal, Hyperbolic, Yield Density, Linear, Polynomial, Dose Response, Pharmacology, Equilibrium and Inhibition. * Levenberg-Marquardt fitting algorithm. A range of statistical calculations can also be applied to the data from within the spreadsheet. Example statistics include: * ''F''-test and ''t''-test * Area under the curve / ROC * Confidence intervals * Error values relating to parameter values or any point on the curve. Available statistical models include Spearman's rank correlations, Student's '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Numerical Analysis Software
Listed here are notable end-user computer applications intended for use with numerical or data analysis: Numerical-software packages General-purpose computer algebra systems Interface-oriented Language-oriented Historically significant * Expensive Desk Calculator written for the TX-0 and PDP-1 The PDP-1 (''Programmed Data Processor-1'') is the first computer in Digital Equipment Corporation's PDP series and was first produced in 1959. It is famous for being the computer most important in the creation of hacker culture at Massachusetts ... in the late 1950s or early 1960s. * S is an (array-based) programming language with strong numerical support. R is an implementation of the S language. See also References {{DEFAULTSORT:Numerical Analysis Software Lists of software Mathematics-related lists *Software ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
IDBS
A bioinformatics workflow management system is a specialized form of workflow management system designed specifically to compose and execute a series of computational or data manipulation steps, or a workflow, that relate to bioinformatics. There are currently many different workflow systems. Some have been developed more generally as scientific workflow systems for use by scientists from many different disciplines like astronomy and earth science. All such systems are based on an abstract representation of how a computation proceeds in the form of a directed graph, where each node represents a task to be executed and edges represent either data flow or execution dependencies between different tasks. Each system typically provides a visual front-end, allowing the user to build and modify complex applications with little or no programming expertise. Examples In alphabetical order, some examples of bioinformatics workflow management systems include: * Anduril bioinformatics an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hyperbolic Function
In mathematics, hyperbolic functions are analogues of the ordinary trigonometric functions, but defined using the hyperbola rather than the circle. Just as the points form a circle with a unit radius, the points form the right half of the unit hyperbola. Also, similarly to how the derivatives of and are and respectively, the derivatives of and are and respectively. Hyperbolic functions occur in the calculations of angles and distances in hyperbolic geometry. They also occur in the solutions of many linear differential equations (such as the equation defining a catenary), cubic equations, and Laplace's equation in Cartesian coordinates. Laplace's equations are important in many areas of physics, including electromagnetic theory, heat transfer, fluid dynamics, and special relativity. The basic hyperbolic functions are: * hyperbolic sine "" (), * hyperbolic cosine "" (),''Collins Concise Dictionary'', p. 328 from which are derived: * hyperbolic tangent "" (), * hyp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spearman's Rank Correlation
In statistics, Spearman's rank correlation coefficient or Spearman's ''ρ'', named after Charles Spearman and often denoted by the Greek letter \rho (rho) or as r_s, is a nonparametric measure of rank correlation ( statistical dependence between the rankings of two variables). It assesses how well the relationship between two variables can be described using a monotonic function. The Spearman correlation between two variables is equal to the Pearson correlation between the rank values of those two variables; while Pearson's correlation assesses linear relationships, Spearman's correlation assesses monotonic relationships (whether linear or not). If there are no repeated data values, a perfect Spearman correlation of +1 or −1 occurs when each of the variables is a perfect monotone function of the other. Intuitively, the Spearman correlation between two variables will be high when observations have a similar (or identical for a correlation of 1) rank (i.e. relative positio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Confidence Interval
In frequentist statistics, a confidence interval (CI) is a range of estimates for an unknown parameter. A confidence interval is computed at a designated ''confidence level''; the 95% confidence level is most common, but other levels, such as 90% or 99%, are sometimes used. The confidence level represents the long-run proportion of corresponding CIs that contain the true value of the parameter. For example, out of all intervals computed at the 95% level, 95% of them should contain the parameter's true value. Factors affecting the width of the CI include the sample size, the variability in the sample, and the confidence level. All else being the same, a larger sample produces a narrower confidence interval, greater variability in the sample produces a wider confidence interval, and a higher confidence level produces a wider confidence interval. Definition Let be a random sample from a probability distribution with statistical parameter , which is a quantity to be estimate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Receiver Operating Characteristic
A receiver operating characteristic curve, or ROC curve, is a graphical plot that illustrates the diagnostic ability of a binary classifier system as its discrimination threshold is varied. The method was originally developed for operators of military radar receivers starting in 1941, which led to its name. The ROC curve is created by plotting the true positive rate (TPR) against the false positive rate (FPR) at various threshold settings. The true-positive rate is also known as sensitivity, recall or ''probability of detection''. The false-positive rate is also known as ''probability of false alarm'' and can be calculated as (1 − specificity). The ROC can also be thought of as a plot of the power as a function of the Type I Error of the decision rule (when the performance is calculated from just a sample of the population, it can be thought of as estimators of these quantities). The ROC curve is thus the sensitivity or recall as a function of fall-out. In general, if the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Area Under The Curve
In mathematics, an integral assigns numbers to functions in a way that describes displacement, area, volume, and other concepts that arise by combining infinitesimal data. The process of finding integrals is called integration. Along with differentiation, integration is a fundamental, essential operation of calculus,Integral calculus is a very well established mathematical discipline for which there are many sources. See and , for example. and serves as a tool to solve problems in mathematics and physics involving the area of an arbitrary shape, the length of a curve, and the volume of a solid, among others. The integrals enumerated here are those termed definite integrals, which can be interpreted as the signed area of the region in the plane that is bounded by the graph of a given function between two points in the real line. Conventionally, areas above the horizontal axis of the plane are positive while areas below are negative. Integrals also refer to the concept of a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
T-test
A ''t''-test is any statistical hypothesis testing, statistical hypothesis test in which the test statistic follows a Student's t-distribution, Student's ''t''-distribution under the null hypothesis. It is most commonly applied when the test statistic would follow a normal distribution if the value of a Scale parameter, scaling term in the test statistic were known (typically, the scaling term is unknown and therefore a nuisance parameter). When the scaling term is estimated based on the data, the test statistic—under certain conditions—follows a Student's ''t'' distribution. The ''t''-test's most common application is to test whether the means of two populations are different. History The term "''t''-statistic" is abbreviated from "hypothesis test statistic". In statistics, the t-distribution was first derived as a Posterior probability, posterior distribution in 1876 by Friedrich Robert Helmert, Helmert and Jacob Lüroth, Lüroth. The t-distribution also appeared in a more ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
F-test
An ''F''-test is any statistical test in which the test statistic has an ''F''-distribution under the null hypothesis. It is most often used when comparing statistical models that have been fitted to a data set, in order to identify the model that best fits the population from which the data were sampled. Exact "''F''-tests" mainly arise when the models have been fitted to the data using least squares. The name was coined by George W. Snedecor, in honour of Ronald Fisher. Fisher initially developed the statistic as the variance ratio in the 1920s. Common examples Common examples of the use of ''F''-tests include the study of the following cases: * The hypothesis that the means of a given set of normally distributed populations, all having the same standard deviation, are equal. This is perhaps the best-known ''F''-test, and plays an important role in the analysis of variance (ANOVA). * The hypothesis that a proposed regression model fits the data well. See Lack-of-fit sum of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spreadsheet
A spreadsheet is a computer application for computation, organization, analysis and storage of data in tabular form. Spreadsheets were developed as computerized analogs of paper accounting worksheets. The program operates on data entered in cells of a table. Each cell may contain either numeric or text data, or the results of formulas that automatically calculate and display a value based on the contents of other cells. The term ''spreadsheet'' may also refer to one such electronic document. Spreadsheet users can adjust any stored value and observe the effects on calculated values. This makes the spreadsheet useful for "what-if" analysis since many cases can be rapidly investigated without manual recalculation. Modern spreadsheet software can have multiple interacting sheets and can display data either as text and numerals or in graphical form. Besides performing basic arithmetic and mathematical functions, modern spreadsheets provide built-in functions for common financial a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Levenberg–Marquardt Algorithm
In mathematics and computing, the Levenberg–Marquardt algorithm (LMA or just LM), also known as the damped least-squares (DLS) method, is used to solve non-linear least squares problems. These minimization problems arise especially in least squares curve fitting. The LMA interpolates between the Gauss–Newton algorithm (GNA) and the method of gradient descent. The LMA is more robust than the GNA, which means that in many cases it finds a solution even if it starts very far off the final minimum. For well-behaved functions and reasonable starting parameters, the LMA tends to be slower than the GNA. LMA can also be viewed as Gauss–Newton using a trust region approach. The algorithm was first published in 1944 by Kenneth Levenberg, while working at the Frankford Army Arsenal. It was rediscovered in 1963 by Donald Marquardt, who worked as a statistician at DuPont, and independently by Girard, Wynne and Morrison. The LMA is used in many software applications for solving gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme Inhibitor
An enzyme inhibitor is a molecule that binds to an enzyme and blocks its activity. Enzymes are proteins that speed up chemical reactions necessary for life, in which substrate molecules are converted into products. An enzyme facilitates a specific chemical reaction by binding the substrate to its active site, a specialized area on the enzyme that accelerates the most difficult step of the reaction. An enzyme inhibitor stops ("inhibits") this process, either by binding to the enzyme's active site (thus preventing the substrate itself from binding) or by binding to another site on the enzyme such that the enzyme's catalysis of the reaction is blocked. Enzyme inhibitors may bind reversibly or irreversibly. Irreversible inhibitors form a chemical bond with the enzyme such that the enzyme is inhibited until the chemical bond is broken. By contrast, reversible inhibitors bind non-covalently and may spontaneously leave the enzyme, allowing the enzyme to resume its function. Reve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
