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William Hewson (surgeon)
William Hewson (14 November 1739 – 1 May 1774) was a British surgeon, anatomist and physiologist who has been referred to as the "father of haematology". Biography Born in Hexham, Northumberland, Hewson initially studied in 1753 at the Newcastle Infirmary, Newcastle upon Tyne (which later became the Royal Victoria Infirmary) under its founder Richard Lambert and much later in the winter of 1761/1762 in Edinburgh and was a student, and later an assistant, of William Hunter. In 1768 he was elected to the American Philosophical Society, he was awarded the Copley Medal in 1769, and elected to the Royal Society in 1770. His major contribution was in isolating fibrin, a key protein in the blood coagulation process. His Copley work came when he showed the existence of lymph vessels in animals and explained their function by hypothesizing the existence of a human lymphatic system. He also demonstrated that red blood cells were discoid, rather than spherical as had been previously su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hexham
Hexham ( ) is a market town and civil parishes in England, civil parish in Northumberland, England, on the south bank of the River Tyne, formed by the confluence of the North Tyne and the South Tyne at Warden, Northumberland, Warden nearby, and close to Hadrian's Wall. Hexham was the administrative centre for the Tynedale district from 1974 to 2009. In 2011, it had a population of 13,097. Smaller towns and villages around Hexham include Corbridge, Riding Mill, Stocksfield and Wylam to the east, Acomb, Northumberland, Acomb and Bellingham, Northumberland, Bellingham to the north, Allendale, Northumberland, Allendale to the south and Haydon Bridge, Bardon Mill and Haltwhistle to the west. Newcastle upon Tyne is to the east and Carlisle to the west. History Hexham Abbey originated as a monastery founded by Wilfrid in 674. The crypt of the original monastery survives, and incorporates many stones taken from nearby Roman ruins, probably Coria (Corbridge), Corbridge or Hadrian's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Newcastle University
Newcastle University (legally the University of Newcastle upon Tyne) is a UK public university, public research university based in Newcastle upon Tyne, North East England. It has overseas campuses in Singapore and Malaysia. The university is a red brick university and a member of the Russell Group, an association of research-intensive UK universities. The university finds its roots in the School of Medicine and Surgery (later the College of Medicine), established in 1834, and the Edward Fenwick Boyd#College of Physical Science, College of Physical Science (later renamed Armstrong College), founded in 1871. These two colleges came to form the larger division of the federal University of Durham, with the Durham Colleges forming the other. The Newcastle colleges merged to form King's College in 1937. In 1963, following an Act of Parliament, King's College became the University of Newcastle upon Tyne. The university subdivides into three faculties: the Faculty of Humanities and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benjamin Franklin House
Benjamin Franklin House is a museum in a terraced Georgian house at 36 Craven Street, London, close to Trafalgar Square. It is the last-standing former residence of Benjamin Franklin, one of the Founding Fathers of the United States. The house dates from c. 1730, and Franklin lived and worked there for sixteen years.Tom Huntington "Franklin's Last Home," ''American Heritage'', April/May 2006. The museum opened to the public on 17 January 2006. The chairman is American-British investment banker and philanthropist . The house is |
Craven Street
Craven Street is a street in the City of Westminster, London, near Strand. A number of notable historical figures have lived in the street which was the home of Benjamin Franklin when he lived in London before the American Revolution. History The street was originally known as Spur Alley. It was rebuilt around 1730 when the land was owned by the Craven family and it received its current name then. Location Craven Street runs from Strand in the north to Northumberland Avenue in the south. Corner House Street and Hungerford Lane join Craven Street in the north and half way along Craven Street it is crossed by Craven Passage which is pedestrian only and joins Craven Street to Northumberland Street and Hungerford Lane. Hungerford Lane rejoins Craven Street at its southern end. Residents Mark Akenside, author of '' The Pleasures of the Imagination'', lived at No. 33 from 1759 to 1761. Benjamin Franklin lived at No. 36 for sixteen years before the American Revolution. The house i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benjamin Franklin
Benjamin Franklin ( April 17, 1790) was an American polymath who was active as a writer, scientist, inventor, statesman, diplomat, printer, publisher, and political philosopher. Encyclopædia Britannica, Wood, 2021 Among the leading intellectuals of his time, Franklin was one of the Founding Fathers of the United States, a drafter and signer of the United States Declaration of Independence, and the first United States Postmaster General. As a scientist, he was a major figure in the American Enlightenment and the history of physics for his studies of electricity, and for charting and naming the current still known as the Gulf Stream. As an inventor, he is known for the lightning rod, bifocals, and the Franklin stove, among others. He founded many civic organizations, including the Library Company, Philadelphia's first fire department, and the University of Pennsylvania. Isaacson, 2004, p. Franklin earned the title of "The First American" for his early and indefa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
London
London is the capital and largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a major settlement for two millennia. The City of London, its ancient core and financial centre, was founded by the Romans as '' Londinium'' and retains its medieval boundaries.See also: Independent city § National capitals The City of Westminster, to the west of the City of London, has for centuries hosted the national government and parliament. Since the 19th century, the name "London" has also referred to the metropolis around this core, historically split between the counties of Middlesex, Essex, Surrey, Kent, and Hertfordshire, which largely comprises Greater London, governed by the Greater London Authority.The Greater London Authority consists of the Mayor of London and the London Assembly. The London Mayor is distinguished fr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Membrane
The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment (the extracellular space). The cell membrane consists of a lipid bilayer, made up of two layers of phospholipids with cholesterols (a lipid component) interspersed between them, maintaining appropriate membrane fluidity at various temperatures. The membrane also contains membrane proteins, including integral proteins that span the membrane and serve as membrane transporters, and peripheral proteins that loosely attach to the outer (peripheral) side of the cell membrane, acting as enzymes to facilitate interaction with the cell's environment. Glycolipids embedded in the outer lipid layer serve a similar purpose. The cell membrane controls the movement of substances in and out of cells and organelles, being selectively permeable to ions a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anton Van Leeuwenhoek
Antonie Philips van Leeuwenhoek ( ; ; 24 October 1632 – 26 August 1723) was a Dutch microbiologist and microscopist in the Golden Age of Dutch science and technology. A largely self-taught man in science, he is commonly known as " the Father of Microbiology", and one of the first microscopists and microbiologists. Van Leeuwenhoek is best known for his pioneering work in microscopy and for his contributions toward the establishment of microbiology as a scientific discipline. Raised in Delft, Dutch Republic, van Leeuwenhoek worked as a draper in his youth and founded his own shop in 1654. He became well recognized in municipal politics and developed an interest in lensmaking. In the 1670s, he started to explore microbial life with his microscope. This was one of the notable achievements of the Golden Age of Dutch exploration and discovery (). Using single-lensed microscopes of his own design and make, van Leeuwenhoek was the first to observe and to experiment with microbe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Red Blood Cell
Red blood cells (RBCs), also referred to as red cells, red blood corpuscles (in humans or other animals not having nucleus in red blood cells), haematids, erythroid cells or erythrocytes (from Greek ''erythros'' for "red" and ''kytos'' for "hollow vessel", with ''-cyte'' translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system. RBCs take up oxygen in the lungs, or in fish the gills, and release it into tissues while squeezing through the body's capillaries. The cytoplasm of a red blood cell is rich in hemoglobin, an iron-containing biomolecule that can bind oxygen and is responsible for the red color of the cells and the blood. Each human red blood cell contains approximately 270 million hemoglobin molecules. The cell membrane is composed of proteins and lipids, and this structure provides properties essential for physiolo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lymphatic System
The lymphatic system, or lymphoid system, is an organ system in vertebrates that is part of the immune system, and complementary to the circulatory system. It consists of a large network of lymphatic vessels, lymph nodes, lymphatic or lymphoid organs, and lymphoid tissues. The vessels carry a clear fluid called lymph (the Latin word ''lympha'' refers to the deity of fresh water, "Lympha") back towards the heart, for re-circulation. Unlike the circulatory system that is a closed system, the lymphatic system is open. The human circulatory system processes an average of 20 litres of blood per day through capillary filtration, which removes plasma from the blood. Roughly 17 litres of the filtered blood is reabsorbed directly into the blood vessels, while the remaining three litres are left in the interstitial fluid. One of the main functions of the lymphatic system is to provide an accessory return route to the blood for the surplus three litres. The other main function is that of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coagulation
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It potentially results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The mechanism of coagulation involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin. Coagulation begins almost instantly after an injury to the endothelium lining a blood vessel. Exposure of blood to the subendothelial space initiates two processes: changes in platelets, and the exposure of subendothelial tissue factor to plasma factor VII, which ultimately leads to cross-linked fibrin formation. Platelets immediately form a plug at the site of injury; this is called ''primary hemostasis. Secondary hemostasis'' occurs simultaneously: additional coagulation (clotting) factors beyond factor VII ( listed below) respond in a cascade to form fibrin strands, which strengthen the platelet plug. Disorders of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
