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Wikiproteins
WikiProfessional (Wiki for Professionals) was an attempt to create a web-based research environment for semantic searching, providing an intuitive tool for analyzing and relating concepts. When data is entered, the system semantically analyzed and recognized co-occurrences between different entities. The results were visualized through a "Knowlet," which is a visual representation of semantic distance between associated entities. This Knowlet is then used to notify persons that have subscribed to these entities, enabling a rapid data interchange between collaborators. The major focus was proteins, using a portal named WikiProteins. It contained over a hundred million entries, "melding some of the key biomedical databases into a single information resource". Sources included: * 245,000 Proteins from UniProt/Swiss-Prot * 24,000 Gene Ontology terms from the GO Consortium * 880,000 Concepts from UMLS/ NLM * 112,000,000 Unique sentences from Medline The project never passed the o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Semantic Search
Semantic search denotes search with meaning, as distinguished from lexical search where the search engine looks for literal matches of the query words or variants of them, without understanding the overall meaning of the query. Semantic search seeks to improve search accuracy by understanding the searcher's intent and the contextual meaning of terms as they appear in the searchable dataspace, whether on the Web or within a closed system, to generate more relevant results. Content that ranks well in semantic search is well-written in a natural voice, focuses on the user's intent, and considers related topics that the user may look for in the future. Some authors regard semantic search as a set of techniques for retrieving knowledge from richly structured data sources like ontologies and XML as found on the Semantic Web. Such technologies enable the formal articulation of domain knowledge at a high level of expressiveness and could enable the user to specify their intent in more de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medline
MEDLINE (Medical Literature Analysis and Retrieval System Online, or MEDLARS Online) is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medicine, nursing, pharmacy, dentistry, veterinary medicine, and health care. MEDLINE also covers much of the literature in biology and biochemistry, as well as fields such as molecular evolution. Compiled by the United States National Library of Medicine (NLM), MEDLINE is freely available on the Internet and searchable via PubMed and NLM's National Center for Biotechnology Information's Entrez system. History MEDLARS (Medical Literature Analysis and Retrieval System) is a computerised biomedical bibliographic retrieval system. It was launched by the National Library of Medicine in 1964 and was the first large scale, computer based, retrospective search service available to the general public. Initial development of MEDLARS Since 1879, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metadata
Metadata is "data that provides information about other data", but not the content of the data, such as the text of a message or the image itself. There are many distinct types of metadata, including: * Descriptive metadata – the descriptive information about a resource. It is used for discovery and identification. It includes elements such as title, abstract, author, and keywords. * Structural metadata – metadata about containers of data and indicates how compound objects are put together, for example, how pages are ordered to form chapters. It describes the types, versions, relationships, and other characteristics of digital materials. * Administrative metadata – the information to help manage a resource, like resource type, permissions, and when and how it was created. * Reference metadata – the information about the contents and quality of statistical data. * Statistical metadata – also called process data, may describe processes that collect, process, or produce st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leiden University Medical Centre
Leiden University Medical Center (Dutch: ''Leids Universitair Medisch Centrum'') or LUMC is the university hospital affiliated with Leiden University, of which it forms the medical faculty. It is located in Leiden, Netherlands. LUMC is a modern university medical center for research, education and patient care. Its research practice ranges from pure fundamental medical research to applied clinical research. Patient care The hospital has clinical departments of all medical specialties, and acts as a tertiary referral centre for the northern part of the province of South Holland. Special units include: * Ophthalmology * Neurosurgery * Cardiothoracic surgery * Neonatal and pediatric surgery and intensive care * Pediatric oncology * Orthopedic medicine * Biliary surgery * Rheumatology * Level I trauma center Research The LUMC aims at identifying the causes of disease, improving diagnosis, prevention, and ultimately developing effective treatments. Within LUMC different specialists ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erasmus MC
Erasmus University Medical Center (Erasmus MC or EMC) based in Rotterdam, Netherlands, affiliated with Erasmus University and home to its faculty of medicine, is the largest and one of the most authoritative scientific University Medical Centers in Europe. The hospital is the largest of the eight university medical centers in the Netherlands, both in terms of turnover and number of beds. The Erasmus MC ranks #1 of the top European institution in clinical medicine and #20 in the world according to the Times Higher Education rankings. Structure The hospital has three locations: * Erasmus MC – the main location. * Erasmus MC Sophia Children's Hospital, the pediatric hospital, closely connected to the main location by a raised glass hallway. * Erasmus MC Cancer Institute, specialized in oncology. Special units include: * Neurosurgery * Cardiothoracic surgery * Neonatal and pediatric surgery and intensive care * Pediatric oncology * Level I trauma center (including trauma helicopter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barend Mons
Barend Mons (born 1957, The Hague) is a molecular biologist by training and a leading FAIR data specialist. The first decade of his scientific career he spent on fundamental research on malaria parasites and later on translational research for malaria vaccines. In the year 2000 he switched to advanced data stewardship and (biological) systems analytics. He is currently a professor in Leiden and most known for innovations in scholarly collaboration, especially nanopublications, knowledge graph based discovery and most recently the FAIR data initiative and GO FAIR. Since 2012 he is a Professor in biosemantics in the Department of Human Genetics at the Leiden University Medical Center (LUMC) in The Netherlands. In 2015 Barend was appointed chair of the High Level Expert Group on the European Open Science Cloud. Since 2017 Barend is heading the International Support and Coordination office of the GO FAIR initiative. He is also the elected president of CODATA, the standing committ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Knewco
Barend Mons (born 1957, The Hague) is a molecular biologist by training and a leading FAIR data specialist. The first decade of his scientific career he spent on fundamental research on malaria parasites and later on translational research for malaria vaccines. In the year 2000 he switched to advanced data stewardship and (biological) systems analytics. He is currently a professor in Leiden and most known for innovations in scholarly collaboration, especially nanopublications, knowledge graph based discovery and most recently the FAIR data initiative and GO FAIR. Since 2012 he is a Professor in biosemantics in the Department of Human Genetics at the Leiden University Medical Center (LUMC) in The Netherlands. In 2015 Barend was appointed chair of the High Level Expert Group on the European Open Science Cloud. Since 2017 Barend is heading the International Support and Coordination office of the GO FAIR initiative. He is also the elected president of CODATA, the standing committe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States National Library Of Medicine
The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library. Located in Bethesda, Maryland, the NLM is an institute within the National Institutes of Health. Its collections include more than seven million books, journals, technical reports, manuscripts, microfilms, photographs, and images on medicine and related sciences, including some of the world's oldest and rarest works. The current director of the NLM is Patricia Flatley Brennan.National Library of Medicine Welcomes New Director Dr. Patricia Flatley Brennan . ''National Library of Medicine''. August 15, 2016. History The precursor o ...[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Semantics (computer Science)
In programming language theory, semantics is the rigorous mathematical study of the meaning of programming languages. Semantics assigns computational meaning to valid strings in a programming language syntax. Semantics describes the processes a computer follows when executing a program in that specific language. This can be shown by describing the relationship between the input and output of a program, or an explanation of how the program will be executed on a certain platform, hence creating a model of computation. History In 1967, Robert W. Floyd publishes the paper ''Assigning meanings to programs''; his chief aim is "a rigorous standard for proofs about computer programs, including proofs of correctness, equivalence, and termination". Floyd further writes: A semantic definition of a programming language, in our approach, is founded on a syntactic definition. It must specify which of the phrases in a syntactically correct program represent commands, and what conditions ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UMLS
The Unified Medical Language System (UMLS) is a compendium of many controlled vocabularies in the biomedical sciences (created 1986). It provides a mapping structure among these vocabularies and thus allows one to translate among the various terminology systems; it may also be viewed as a comprehensive thesaurus and ontology of biomedical concepts. UMLS further provides facilities for natural language processing. It is intended to be used mainly by developers of systems in medical informatics. UMLS consists of Knowledge Sources (databases) and a set of software tools. The UMLS was designed and is maintained by the US National Library of Medicine, is updated quarterly and may be used for free. The project was initiated in 1986 by Donald A.B. Lindberg, M.D., then Director of the Library of Medicine, and directed by Betsy Humphreys. Purpose and applications The number of biomedical resources available to researchers is enormous. Often this is a problem due to the large volume of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Ontology
The Gene Ontology (GO) is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species. More specifically, the project aims to: 1) maintain and develop its controlled vocabulary of gene and gene product attributes; 2) annotate genes and gene products, and assimilate and disseminate annotation data; and 3) provide tools for easy access to all aspects of the data provided by the project, and to enable functional interpretation of experimental data using the GO, for example via enrichment analysis. GO is part of a larger classification effort, the Open Biomedical Ontologies, being one of the Initial Candidate Members of the OBO Foundry. Whereas gene nomenclature focuses on gene and gene products, the Gene Ontology focuses on the function of the genes and gene products. The GO also extends the effort by using markup language to make the data (not only of the genes and their products but also of curated attributes) machine read ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
