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Welsh Blood Service
The Welsh Blood Service is a division of Velindre University NHS Trust responsible for the collection of blood in Wales, and of the distribution of blood products to hospitals within the country, as well as other related functions. History The service was established in 1946. At that time the only test carried out was for syphilis. Since then more than 10 million units of blood have been donated in Wales. Operations The Welsh Blood Service's roles include * the collection of voluntary, non-remunerated Blood donation, blood, Plateletpheresis, platelet and Hematopoietic stem cell transplantation, stem-cell donations from the general public. * distribution of blood products to the customer hospitals of Wales. * provision of an antenatal screening service to hospitals. * specialist laboratory services, assisting the investigation of complex serological problems. * the 'Welsh Transplantation & Immunogenetics Laboratory'', providing direct support to local providers of Renal and Stem ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Velindre University NHS Trust
Felindre is a rural village in southern Wales. Felindre is located in the far north of Swansea, in the electoral ward of Mawr. The nearby Lower Lliw Reservoirs are a popular venue for walking and fishing. The water mill in the village was working until the late 1960s, there was also an abattoir and a post office in the village. It has three shops. There is also a public house in the village, the Shepherds Inn. The primary school in the village was Welsh speaking and closed in 2019. Felindre works site In 1956, the Steel Company of Wales opened a tinplate works at Felindre to complement new facilities at Port Talbot and Trostre. In 1967, the Steel Company of Wales was nationalised, becoming part of British Steel Corporation, which inherited the additional tinplate works at Ebbw Vale Steelworks. By 1970, Felindre works employed 2,500 people and was producing 490,000 tonnes of tinplate per annum. Having already closed the tinplate works at Port Talbot, on review of the three rema ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Talbot Green
Talbot Green ( cy, Tonysguboriau "lea of the barns") is a town (and electoral ward) just north of the M4 motorway, in the County Borough of Rhondda Cynon Taf, Wales in the United Kingdom. The town is part of Llantrisant Community Council. Geography Talbot Green is located at the mouth of the short and mountainous Ely Valley, between Mynydd Garthmaelwg (Llantrisant forest) and Y Graig (Llantrisant). The River Ely runs through along the town boundary before continuing to Pontyclun, running alongside the Warehouses of A F Blakemore & Son ltd, who run a portion of the SPAR UK retail chain. The town is bordered by the hill town of Llantrisant to the east, the Village of Pontyclun to the South and Llanharan a few miles to the West. Transport left, Sign showing the transport links in the area The area has links to the rest of Wales with the A4119 linking it in the south to the M4 Motorway, and to the north to the South Wales Valleys. The Talbot Green by-pass opened in 1991 to reliev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pontyclun
Pontyclun (or Pont-y-clun) is a village and community located in the county borough of Rhondda Cynon Taf, Wales. Like the surrounding towns, it has seen a sharp increase in its population in the last ten years as people migrate south from the South Wales Valleys and west from the capital city of Cardiff. Pontyclun translates from the Welsh language as 'bridge verthe River Clun', the Clun being a tributary of the River Ely that runs through Pontyclun. A bridge crosses the Afon Clun just above its confluence with the Ely. The village is served by Pontyclun railway station on the South Wales Main Line. It has its own local rugby club. The village falls under the remit of Pontyclun Community Council, which represents the communities of Brynsadler, Castell y Mwnws, Groes-faen, Miskin, Mwyndy, Pontyclun, Talygarn, and Ynysddu History The influx of workers for the iron ore and coal mining industries, and the coming of the South Wales Railway in 1851, changed Pontyclun from a far ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood
Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in the circulatory system is also known as ''peripheral blood'', and the blood cells it carries, ''peripheral blood cells''. Blood is composed of blood cells suspended in blood plasma. Plasma, which constitutes 55% of blood fluid, is mostly water (92% by volume), and contains proteins, glucose, mineral ions, hormones, carbon dioxide (plasma being the main medium for excretory product transportation), and blood cells themselves. Albumin is the main protein in plasma, and it functions to regulate the colloidal osmotic pressure of blood. The blood cells are mainly red blood cells (also called RBCs or erythrocytes), white blood cells (also called WBCs or leukocytes) and platelets (also called thrombocytes). The most abundant cells in vertebrate blo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wales
Wales ( cy, Cymru ) is a Countries of the United Kingdom, country that is part of the United Kingdom. It is bordered by England to the Wales–England border, east, the Irish Sea to the north and west, the Celtic Sea to the south west and the Bristol Channel to the south. It had a population in 2021 of 3,107,500 and has a total area of . Wales has over of coastline and is largely mountainous with its higher peaks in the north and central areas, including Snowdon (), its highest summit. The country lies within the Temperateness, north temperate zone and has a changeable, maritime climate. The capital and largest city is Cardiff. Welsh national identity emerged among the Celtic Britons after the Roman withdrawal from Britain in the 5th century, and Wales was formed as a Kingdom of Wales, kingdom under Gruffydd ap Llywelyn in 1055. Wales is regarded as one of the Celtic nations. The Conquest of Wales by Edward I, conquest of Wales by Edward I of England was completed by 1283, th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Donation
A blood donation occurs when a person voluntarily has blood drawn and used for blood transfusion, transfusions and/or made into biopharmaceutical medications by a process called Blood fractionation, fractionation (separation of whole blood components). Donation may be of whole blood, or of specific components directly (apheresis). Blood banks often participate in the collection process as well as the procedures that follow it. Today in the developed world, most blood donors are unpaid volunteers who donate blood for a community supply. In some countries, established supplies are limited and donors usually give blood when family or friends need a transfusion (directed donation). Many donors donate for several reasons, such as a form of charity, general awareness regarding the demand for blood, increased confidence in oneself, helping a personal friend or relative, and social pressure. Despite the many reasons that people donate, not enough potential donors actively donate. Ho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plateletpheresis
Plateletpheresis (more accurately called thrombocytapheresis or thrombapheresis, though these names are rarely used) is the process of collecting thrombocytes, more commonly called platelets, a component of blood involved in blood clotting. The term specifically refers to the method of collecting the platelets, which is performed by a device used in blood donation that separates the platelets and returns other portions of the blood to the donor. Platelet transfusion can be a life-saving procedure in preventing or treating serious complications from bleeding and hemorrhage in patients who have disorders manifesting as thrombocytopenia (low platelet count) or platelet dysfunction. This process may also be used therapeutically to treat disorders resulting in extraordinarily high platelet counts such as essential thrombocytosis. Platelet transfusion Platelet transfusions are traditionally given to those undergoing chemotherapy for leukemia, multiple myeloma, those with aplastic a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hematopoietic Stem Cell Transplantation
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood in order to replicate inside of a patient and to produce additional normal blood cells. It may be autologous (the patient's own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an identical twin). It is most often performed for patients with certain cancers of the blood or bone marrow, such as multiple myeloma or leukemia. In these cases, the recipient's immune system is usually destroyed with radiation or chemotherapy before the transplantation. Infection and graft-versus-host disease are major complications of allogeneic HSCT. HSCT remains a dangerous procedure with many possible complications; it is reserved for patients with life-threatening diseases. As survival following the procedure has increased, its use has expanded beyond cancer to autoimmun ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Histocompatibility
Histocompatibility, or tissue compatibility, is the property of having the same, or sufficiently similar, alleles of a set of genes called human leukocyte antigens (HLA), or major histocompatibility complex (MHC). Each individual expresses many unique HLA proteins on the surface of their cells, which signal to the immune system whether a cell is part of the self or an invading organism. T cells recognize foreign HLA molecules and trigger an immune response to destroy the foreign cells. Histocompatibility testing is most relevant for topics related to whole organ, tissue, or stem cell transplants, where the similarity or difference between the donor's HLA alleles and the recipient's triggers the immune system to reject the transplant. The wide variety of potential HLA alleles lead to unique combinations in individuals and make matching difficult. Discovery The discovery of the MHC and role of histocompatibility in transplantation was a combined effort of many scientists in the 20t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunogenetics
Immunogenetics or immungenetics is the branch of Medical Immunology and Medical Genetics that explores the relationship between the immune system and genetics. Autoimmune diseases, such as type 1 diabetes, are complex genetic traits which result from defects in the immune system. Identification of genes defining the immune defects may identify new target genes for therapeutic approaches. Alternatively, genetic variations can also help to define the immunological pathway leading to disease. Origin The term immunogenetics is based on the two words immunology and genetics, and is defined as "a sub discipline of genetics which deals with the genetic basis of the immune response (immunity)" according to MeSH. Genetics (based on Greek γενεά ''geneá'' "descent" and γένεσις ''génesis'' "origin") is the science researching the transfer of characteristics from one generation to the next. The genes of an organism (strands of DNA) and the transfer of genes from the parent to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NHS Blood And Transplant
NHS Blood and Transplant is an executive non-departmental public body of the United Kingdom's Department of Health and Social Care. It was established on 1 October 2005 to take over the responsibilities of two separate NHS agencies: UK Transplant (now renamed Organ Donation and Transplantation), founded by Dr. Geoffrey Tovey in 1972, and the National Blood Service (now renamed Blood Donation). Its remit is to provide a reliable, efficient supply of blood, organs and associated services to the NHS. Since NHSBT was established, the organisation has maintained or improved the quality of the services delivered to patients, stabilised the rising cost of blood, and centralised a number of corporate services. Overview It has the responsibility for optimising the supply of blood, organs and tissues and raising the quality, effectiveness and efficiency of blood and transplant services. Its roles are stated to include: * encouraging people to donate organs, blood and tissues * optimising ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research And Development
Research and development (R&D or R+D), known in Europe as research and technological development (RTD), is the set of innovative activities undertaken by corporations or governments in developing new services or products, and improving existing ones. Research and development constitutes the first stage of development of a potential new service or the production process. R&D activities differ from institution to institution, with two primary models of an R&D department either staffed by engineers and tasked with directly developing new products, or staffed with industrial scientists and tasked with applied research in scientific or technological fields, which may facilitate future product development. R&D differs from the vast majority of corporate activities in that it is not intended to yield immediate profit, and generally carries greater risk and an uncertain return on investment. However R&D is crucial for acquiring larger shares of the market through the marketisation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
