Weber–Christian Disease
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Weber–Christian Disease
Weber–Christian disease, is a cutaneous condition characterized by recurrent subcutaneous nodules that heal with depression of the overlying skin. It is a type of panniculitis. It is a rare disease seen in females 30–60 years of age. It is a recurring inflammation of fatty layers of tissue present beneath the skin. Clinical course is characterised by exacerbations and remissions. Lesions are bilaterally symmetrical and are usually seen in the lower legs. Eponym It is named after Frederick Parkes Weber and Henry Asbury Christian. See also * Alpha-1 antitrypsin deficiency panniculitis * List of cutaneous conditions Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against t ... References External links Conditions of the subcutaneous fat {{Cutaneous-condition-stub ...
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Panniculitis
Panniculitis is a group of diseases whose hallmark is inflammation of subcutaneous adipose tissue (the fatty layer under the skin – panniculus adiposus). Symptoms include tender skin nodules, and systemic signs such as weight loss and fatigue. Restated, an inflammatory disorder primarily localized in the subcutaneous fat is termed a "panniculitis", a group of disorders that may be challenging both for the clinician and the dermatopathologist. The general term for inflammation of any adipose tissue is steatitis. Signs and symptoms Panniculitis can also be classified based on the presence or absence of systemic symptoms. Panniculitis without systemic disease can be a result of trauma or cold. Panniculitis with systemic disease can be caused by: * connective tissue disorders such as lupus erythematosus or scleroderma; * lymphoproliferative disease such as lymphoma or histiocytosis; * pancreatitis or pancreatic cancer; * sarcoidosis with cutaneous involvement (seen in up to 20 pe ...
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Frederick Parkes Weber
Frederick Parkes Weber (8 May 1863 – 2 June 1962) was an English dermatologist and author who practiced medicine in London. Background Weber's father, Sir Hermann David Weber (1823–1918), was a personal physician to Queen Victoria. Weber was educated at Charterhouse and Trinity College, Cambridge. He subsequently studied medicine at St. Bartholomew's Hospital, and abroad at Vienna and Paris. Career Returning to England, he worked (since 1894) at the German Hospital, Dalston (London), later he became House Physician and House Surgeon at St. Bartholomew's Hospital. He was subsequently House Physician at Brompton Hospital and Physician at Mount Vernon Hospital. Weber contributed over 1200 medical articles and wrote 23 books over a period of 50 years. In 1922, he, along with his wife, published a philosophical medical tome called ''Aspects of Death and Correlated Aspects of Life in Art, Epigram, and Poetry''. Weber was a prodigious describer of new and unique dermat ...
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Henry Asbury Christian
Henry Asbury Christian (February 17, 1876 – August 24, 1951), was an American professor of pathology named in the condition Hand–Schüller–Christian disease. Biography Henry Asbury Christian was born in Lynchburg, Virginia on February 17, 1876. He earned A.B. and A.M. degrees from Randolph–Macon College in 1895, an M.D. from Johns Hopkins University in 1900, and an A.M. from Harvard in 1903. He married Elizabeth Sears Seabury on June 30, 1921. He died while on vacation in Whitefield, New Hampshire on August 24, 1951, and was interred in Mount Auburn Cemetery Mount Auburn Cemetery is the first rural cemetery, rural, or garden, cemetery in the United States, located on the line between Cambridge, Massachusetts, Cambridge and Watertown, Massachusetts, Watertown in Middlesex County, Massachusetts, Middl .... References External links Henry A. Christian papers, 1876-1951 (inclusive). H MS b68. Harvard Medical Library, Francis A. Countway Library of Medicine, Boston, ...
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Alpha-1 Antitrypsin Deficiency Panniculitis
Panniculitis is a group of diseases whose hallmark is inflammation of subcutaneous adipose tissue (the fatty layer under the skin – panniculus adiposus). Symptoms include tender skin nodules, and systemic signs such as weight loss and fatigue. Restated, an inflammatory disorder primarily localized in the subcutaneous fat is termed a "panniculitis", a group of disorders that may be challenging both for the clinician and the dermatopathologist. The general term for inflammation of any adipose tissue is steatitis. Signs and symptoms Panniculitis can also be classified based on the presence or absence of systemic symptoms. Panniculitis without systemic disease can be a result of trauma or cold. Panniculitis with systemic disease can be caused by: * connective tissue disorders such as lupus erythematosus or scleroderma; * lymphoproliferative disease such as lymphoma or histiocytosis; * pancreatitis or pancreatic cancer; * sarcoidosis with cutaneous involvement (seen in up to 20 pe ...
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List Of Cutaneous Conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against the external environment. The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin.Burns, Tony; ''et al''. (2006) ''Rook's Textbook of Dermatology CD-ROM''. Wiley-Blackwell. . Within the latter type, the hairs occur in structures called pilosebaceous units, each with hair follicle, sebaceous gland, and associated arrector pili muscle. In the embryo, the epidermis, hair, and glands form from the ectoderm, which is chemically influenced by the underlying mesoderm th ...
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