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Weber's Syndrome
Weber's syndrome, also known as midbrain stroke syndrome or superior alternating hemiplegia, is a form of stroke that affects the medial portion of the midbrain. It involves oculomotor fascicles in the interpeduncular cisterns and cerebral peduncle so it characterizes the presence of an ipsilateral lower motor neuron type oculomotor nerve palsy and contralateral hemiparesis or hemiplegia. Cause It is mainly caused by a midbrain infarction as a result of occlusion of a branch of posterior cerebral artery most commonly or the paramedian branches of basilar bifurcation perforating arteries. This lesion is usually unilateral and affects several structures in the midbrain including: Diagnosis Clinical findings mainly eyeball is down and out ipsilateral lateral squint. Ptosis present as the levator palpebrae superioris nerve supply is disrupted. Pupil dilated and fixed. Contralateral hemiplegia CT scan or MRI might help in delineating the cause or the vessel or region of brain inv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurology
Neurology (from el, wikt:νεῦρον, νεῦρον (neûron), "string, nerve" and the suffix wikt:-logia, -logia, "study of") is the branch of specialty (medicine), medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal cord and the peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system. A neurologist is a physician specializing in neurology and trained to investigate, diagnose and treat neurological disorders. Neurologists treat a myriad of neurologic conditions, including stroke, seizures, movement disorders such as Parkinson's disease, autoimmune neurologic disorders such as multiple sclerosis, headache disorders like migraine and dementias such as Alzheimer's disease. Neurologists may also be involved in clinical research, clinical trials, and basic research, basic or translational research. While neurology is a nonsurgical sp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ipsilateral
Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position provides a definition of what is at the front ("anterior"), behind ("posterior") and so on. As part of defining and describing terms, the body is described through the use of anatomical planes and anatomical axes. The meaning of terms that are used can change depending on whether an organism is bipedal or quadrupedal. Additionally, for some animals such as invertebrates, some terms may not have any meaning at all; for example, an animal that is radially symmetrical will have no anterior surface, but can still have a description that a part is close to the middle ("proximal") or further from the middle ("distal"). International organisations have determined vocabularies that are often used as standard vocabularies for subdisciplines of anatom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medial Pontine Syndrome
Medial inferior pontine syndrome is a condition associated with a contralateral hemiplegia."Medial inferior pontine syndrome" has been described as equivalent to Foville's syndrome. Presentation Although medial pontine syndrome has many similarities to medial medullary syndrome, because it is located higher up the brainstem in the pons, it affects a different set of cranial nuclei. Depending upon the size of the infarct, it can also involve the facial nerve. Cause Medial pontine syndrome results from occlusion of paramedian branches of the basilar artery. Diagnosis Treatment See also * Alternating hemiplegia of childhood * Lateral medullary syndrome * Lateral pontine syndrome * Medial medullary syndrome * Weber's syndrome Weber's syndrome, also known as midbrain stroke syndrome or superior alternating hemiplegia, is a form of stroke that affects the medial portion of the midbrain. It involves oculomotor fascicles in the interpeduncular cisterns and cerebral peduncl . ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medial Medullary Syndrome
Medial medullary syndrome, also known as inferior alternating syndrome, hypoglossal alternating hemiplegia, lower alternating hemiplegia, or Dejerine syndrome, is a type of alternating hemiplegia characterized by a set of clinical features resulting from occlusion of the anterior spinal artery. This results in the infarction of medial part of the medulla oblongata. Presentation The condition usually consists of: Sensation to the face is preserved, due to the sparing of the trigeminal nucleus. The syndrome is said to be "alternating" because the lesion causes symptoms both contralaterally and ipsilaterally. Sensation of pain and temperature is preserved, because the spinothalamic tract is located more laterally in the brainstem and is also not supplied by the anterior spinal artery (instead supplied by the posterior inferior cerebellar arteries and the vertebral arteries). Pathophysiology The anterior spinal artery arises bilaterally as two small branches near the termination ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lateral Pontine Syndrome
A lateral pontine syndrome is a lesion which is similar to the lateral medullary syndrome, but because it occurs in the pons, it also involves the cranial nerve nuclei of the pons. Symptoms Damage to the following areas produces symptoms (from medial to lateral): Causes It can be caused by an interruption to the blood supply of the anterior inferior cerebellar artery The anterior inferior cerebellar artery (AICA) is one of three pairs of arteries that supplies blood to the cerebellum. It arises from the basilar artery on each side at the level of the junction between the medulla oblongata and the pons in the ... or circumferential arteries. Treatment References External links Stroke Syndromes affecting the nervous system {{nervoussystem-disease-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lateral Medullary Syndrome
Lateral medullary syndrome is a neurological disorder causing a range of symptoms due to ischemia in the lateral part of the medulla oblongata in the brainstem. The ischemia is a result of a blockage most commonly in the vertebral artery or the posterior inferior cerebellar artery. Lateral medullary syndrome is also called Wallenberg's syndrome, posterior inferior cerebellar artery (PICA) syndrome and vertebral artery syndrome. Signs and symptoms This syndrome is characterized by sensory deficits that affect the trunk and extremities contralaterally (opposite to the lesion), and sensory deficits of the face and cranial nerves ipsilaterally (same side as the lesion). Specifically a loss of pain and temperature sensation if the lateral spinothalamic tract is involved. The cross body finding is the chief symptom from which a diagnosis can be made. Patients often have difficulty walking or maintaining balance (ataxia), or difference in temperature of an object based on which side of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alternating Hemiplegia Of Childhood
Alternating hemiplegia of childhood (AHC) is an ultra-rare neurological disorder named for the transient episodes, often referred to as "attacks", of hemiplegia (weakness or paralysis) from which those with the disorder suffer. It typically presents before the age of 18 months. These hemiplegic attacks can cause anything from mild weakness to complete paralysis on one or both sides of the body, and they can vary greatly in duration. Attacks may also alternate from one side of the body to the other, or alternate between affecting one or both sides during a single attack. Besides hemiplegia, symptoms of the disorder include an extremely broad range of neurological and developmental impairments which are not well understood. Normally, hemiplegia and other associated symptoms cease completely with sleep, but they may recur upon waking. Most frequently AHC is caused by a spontaneous mutation in the ''ATP1A3'' gene.2. It is an extremely rare disorder – approximately 1 in 1,000,000 peopl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frederick Parkes Weber
Frederick Parkes Weber (8 May 1863 – 2 June 1962) was an English dermatologist and author who practiced medicine in London. Background Weber's father, Sir Hermann David Weber (1823–1918), was a personal physician to Queen Victoria. Weber was educated at Charterhouse and Trinity College, Cambridge. He subsequently studied medicine at St. Bartholomew's Hospital, and abroad at Vienna and Paris. Career Returning to England, he worked (since 1894) at the German Hospital, Dalston (London), later he became House Physician and House Surgeon at St. Bartholomew's Hospital. He was subsequently House Physician at Brompton Hospital and Physician at Mount Vernon Hospital. Weber contributed over 1200 medical articles and wrote 23 books over a period of 50 years. In 1922, he, along with his wife, published a philosophical medical tome called ''Aspects of Death and Correlated Aspects of Life in Art, Epigram, and Poetry''. Weber was a prodigious describer of new and unique dermat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Osler–Weber–Rendu Syndrome
Hereditary hemorrhagic telangiectasia (HHT), also known as Osler–Weber–Rendu disease and Osler–Weber–Rendu syndrome, is a rare autosomal dominant genetic disorder that leads to abnormal blood vessel formation in the skin, mucous membranes, and often in organs such as the lungs, liver, and brain. It may lead to nosebleeds, acute and chronic digestive tract bleeding, and various problems due to the involvement of other organs. Treatment focuses on reducing bleeding from blood vessel lesions, and sometimes surgery or other targeted interventions to remove arteriovenous malformations in organs. Chronic bleeding often requires iron supplements and sometimes blood transfusions. HHT is transmitted in an autosomal dominant fashion, and occurs in one in 5,000–8,000 people in North America. The disease carries the names of Sir William Osler, Henri Jules Louis Marie Rendu, and Frederick Parkes Weber, who described it in the late 19th and early 20th centuries. Signs and symptoms ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sturge–Weber Syndrome
Sturge–Weber syndrome, sometimes referred to as encephalotrigeminal angiomatosis, is a rare congenital neurological and skin disorder. It is one of the phakomatoses and is often associated with port-wine stains of the face, glaucoma, seizures, intellectual disability, and ipsilateral leptomeningeal angioma (cerebral malformations and tumors). Sturge–Weber syndrome can be classified into three different types. Type 1 includes facial and leptomeningeal angiomas as well as the possibility of glaucoma or choroidal lesions. Normally, only one side of the brain is affected. This type is the most common. Type 2 involvement includes a facial angioma (port wine stain) with a possibility of glaucoma developing. There is no evidence of brain involvement. Symptoms can show at any time beyond the initial diagnosis of the facial angioma. The symptoms can include glaucoma, cerebral blood flow abnormalities and headaches. More research is needed on this type of Sturge–Weber syndrome. Type 3 h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hermann David Weber
Sir Herman David Weber FRCP (30 December 1823 – 11 November 1918) was a German physician who practiced medicine in England. Biography Weber attended Gymnasium in Fulda in 1838, but started his medical studies at Marburg University in 1844, graduating from Bonn in 1848. About 1854, he attended Guy's Hospital in London and became a member of the College of Physicians in England in 1855; he was elected a fellow in 1859. For many years, he served as the house physician (aka resident medical officer) at London's German Hospital. Based on his pioneering work on open-air treatment of consumption, he was knighted by Queen Victoria in 1899. Weber's syndrome is named after him. Weber was an avid coin collector, and assembled a significant collection of Greek coins. He was awarded the medal of the Royal Numismatic Society in 1905. Weber married and had children. His son, Frederick Parkes Weber, was also a physician and coin collector. Another son, Frank Weber, was an officer in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
