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Waters Corporation
Waters Corporation is a publicly traded Analytical Laboratory instrument and software company headquartered in Milford, Massachusetts. The company employs more than 7,800 people, with manufacturing facilities located in Milford, Taunton, Massachusetts; Wexford, Ireland and Wilmslow, Cheshire. Waters has Sites in 35 countries globally including Frankfurt, Singapore, India, Germany and in Japan. Waters markets to the laboratory-dependent organization in these market areas: liquid chromatography, mass spectrometry, supercritical fluid chromatography, laboratory informatics, rheometry and microcalorimetry. History The business was started by James (Jim) Logan Waters as Waters Associates in an office in the basement of a police station in Framingham, Massachusetts, in 1958. Waters enrolled in the V-12 Navy College Training Program, an officer training program, and graduated from Columbia University as an ensign with a B.S. degree in Physics in 1946. After stints as a university ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Public Company
A public company is a company whose ownership is organized via shares of stock which are intended to be freely traded on a stock exchange or in over-the-counter markets. A public (publicly traded) company can be listed on a stock exchange (listed company), which facilitates the trade of shares, or not (unlisted public company). In some jurisdictions, public companies over a certain size must be listed on an exchange. In most cases, public companies are ''private'' enterprises in the ''private'' sector, and "public" emphasizes their reporting and trading on the public markets. Public companies are formed within the legal systems of particular states, and therefore have associations and formal designations which are distinct and separate in the polity in which they reside. In the United States, for example, a public company is usually a type of corporation (though a corporation need not be a public company), in the United Kingdom it is usually a public limited company (plc), i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Photometer
A photometer is an instrument that measures the strength of electromagnetic radiation in the range from ultraviolet to infrared and including the visible spectrum. Most photometers convert light into an electric current using a photoresistor, photodiode, or photomultiplier. Photometers measure: *Illuminance *Irradiance *Light absorption * Scattering of light *Reflection of light *Fluorescence *Phosphorescence *Luminescence History Before electronic light sensitive elements were developed, photometry was done by estimation by the eye. The relative luminous flux of a source was compared with a standard source. The photometer is placed such that the illuminance from the source being investigated is equal to the standard source, as the human eye can judge equal illuminance. The relative luminous fluxes can then be calculated as the illuminance decreases proportionally to the inverse square of distance. A standard example of such a photometer consists of a piece of paper with an o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ion-mobility Spectrometry–mass Spectrometry
Ion mobility spectrometry–mass spectrometry (IMS-MS) is an analytical chemistry method that separates gas phase ions based on their interaction with a collision gas and their masses. In the first step, the ions are separated according to their mobility through a buffer gas on a millisecond timescale using an ion mobility spectrometer. The separated ions are then introduced into a mass analyzer in a second step where their mass-to-charge ratios can be determined on a microsecond timescale. The effective separation of analytes achieved with this method makes it widely applicable in the analysis of complex samples such as in proteomics and metabolomics. History Earl W. McDaniel has been called the father of ion mobility mass spectrometry. In the early 1960s, he coupled a low-field ion mobility drift cell to a sector mass spectrometer. The combination of time-of-flight mass spectrometry and ion mobility spectrometry was pioneered in 1963 at Bell Labs. In 1963 McAfee and Edelson pub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hybrid Mass Spectrometer
A hybrid mass spectrometer is a device for tandem mass spectrometry that consists of a combination of two or more '' m/z'' separation devices of different types. Notation The different ''m/z'' separation elements of a hybrid mass spectrometer can be represented by a shorthand notation. The symbol ''Q'' represents a quadrupole mass analyzer, ''q'' is a radio frequency collision quadrupole, ''TOF'' is a time-of-flight mass spectrometer, ''B'' is a magnetic sector and ''E'' is an electric sector. Sector quadrupole A sector instrument can be combined with a collision quadrupole and quadrupole mass analyzer to form a hybrid instrument. A BEqQ configuration with a magnetic sector (B), electric sector (E), collision quadrupole (q) and ''m/z'' selection quadrupole (Q) have been constructed and an instrument with two electric sectors (BEEQ) has been described. Quadrupole time-of-flight A triple quadrupole mass spectrometer with the final quadrupole replaced by a time-of-flight device i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mass Spectrometry Software
Mass spectrometry software is software used for data acquisition, analysis, or representation in mass spectrometry. Proteomics software In protein mass spectrometry, tandem mass spectrometry (also known as MS/MS or MS2) experiments are used for protein/peptide identification. Peptide identification algorithms fall into two broad classes: database search and ''de novo'' search. The former search takes place against a database containing all amino acid sequences assumed to be present in the analyzed sample, whereas the latter infers peptide sequences without knowledge of genomic data. Database search algorithms De novo sequencing algorithms De novo peptide sequencing algorithms are based, in general, on the approach proposed in Bartels ''et al.'' (1990). Homology searching algorithms MS/MS peptide quantification Other software See also * Mass spectrometry data format: for a list of mass spectrometry data viewers and format converters. * List of protein ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MassLynx
MassLynx is a software package to control analytical equipment produced by Waters Corporation including liquid chromatography In chemical analysis, chromatography is a laboratory technique for the separation of a mixture into its components. The mixture is dissolved in a fluid solvent (gas or liquid) called the ''mobile phase'', which carries it through a system (a ... systems such as the ACQUITY UPLC series of UHPLC systems and mass spectrometers such as the Xevo TQ-S. MassLynx is used for hardware control, creating, editing and executing run sequences as well as configuration of acquisition methods. Data treatment is performed in other software such as TargetLynx or ChromaLynx. External links MassLynx on Waters website {{science-software-stub Chromatography software ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromatography Software
Chromatography software is software that collects and analyzes chromatographic results delivered by chromatography detectors. Many chromatography software packages are provided by manufacturers, and many of them only provide a simple interface to acquire data. They also provide different tools to analyze this data. The most common tool is "integration": It computes simple areas to delimit peaks by adding valleys automatically or not. Areas are computed between two valleys, a signal, and a baseline. Applications are also available for simulation of chromatography, for example for teaching, demonstration, or for method development &/or optimization. The following is a list of software and the (unexplained) tools that each provides: See also * Laboratory informatics Laboratory informatics is the specialized application of information technology aimed at optimizing and extending laboratory operations. It encompasses data acquisition (e.g. through sensors and hardware or voice), i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Empower (software)
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Empower may refer to: * EMPOWER, a Thai organization supporting sex workers * EmPower (aircraft power adapter), a standard for 15-volt direct current power outlets in passenger airplanes * Empower (emergy), the flow of emergy (embodied energy) * Empower (company), a marketing company located in Cincinnati, Ohio See also * Empower America, a conservative think tank in the United States * Empower Orphans, a US non-profit organization * Empower Playgrounds, a US company that designs playground systems * Empower Retirement, a US financial holding company * ''Empowered'', an original English-language manga * Empowerment Empowerment is the degree of autonomy and self-determination in people and in communities. This enables them to represent their interests in a responsible and self-determined way, acting on their own authority. It is the process of becoming strong ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Supercritical Fluid Chromatography
Supercritical fluid chromatography (SFC) is a form of normal phase chromatography that uses a supercritical fluid such as carbon dioxide as the mobile phase. It is used for the analysis and purification of low to moderate molecular weight, thermally labile molecules and can also be used for the separation of chiral compounds. Principles are similar to those of high performance liquid chromatography (HPLC), however SFC typically utilizes carbon dioxide as the mobile phase; therefore the entire chromatographic flow path must be pressurized. Because the supercritical phase represents a state in which liquid and gas properties converge, supercritical fluid chromatography is sometimes called convergence chromatography. Applications SFC is used in industry primarily for separation of chiral molecules, and uses the same columns as standard HPLC systems. SFC is now commonly used for achiral separations and purifications in the pharmaceutical industry. Apparatus SFC with CO2 utilizes carb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Millipore Corporation
Merck Millipore was the brand used by Merck KGaA, Merck Group's (not US-based Merck & Co.) global life science business until 2015 when the company re-branded. It was formed when Merck acquired the Millipore Corporation in 2010. Merck is a supplier to the life science industry. The Millipore Corporation was founded in 1954, and listed among the S&P 500 since the early 1990s, as an international biosciences company which makes micrometre, micrometer pore-size filters and tests. In 2015, Merck acquired Sigma-Aldrich and merged it with Merck Millipore. In the United States and Canada, the life science business is now known as Sigma-Aldrich, MilliporeSigma. History Founding In the early 1950s, Lovell Corporation won a contract from the U.S. Army Chemical Engineers to develop and manufacture membrane filtering devices used to separate the molecular components of fluid samples. When the membranes were declassified in 1953 and offered for commercial use, Jack Bush, son of Vannevar Bush ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gel Permeation Chromatography
Gel permeation chromatography (GPC) is a type of size-exclusion chromatography (SEC), that separates analytes on the basis of size, typically in organic solvents. The technique is often used for the analysis of polymers. As a technique, SEC was first developed in 1955 by Lathe and Ruthven.Lathe, G.H.; Ruthven, C.R.J. The Separation of Substance and '1956', ''62'', 665–674. The term ''gel permeation chromatography'' can be traced back to J.C. Moore of the Dow Chemical Company who investigated the technique in 1964. The proprietary column technology was licensed to Waters Corporation, who subsequently commercialized this technology in 1964.Moore, J.C. Gel permeation chromatography. I. A new method for molecular weight distribution of high polymers. ''J. Polym. Sci.'', 1964, ''2'', 835-84 GPC systems and consumables are now also available from a number of manufacturers. It is often necessary to separate polymers, both to analyze them as well as to purify the desired product. When cha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dow Chemical
The Dow Chemical Company, officially Dow Inc., is an American multinational chemical corporation headquartered in Midland, Michigan, United States. The company is among the three largest chemical producers in the world. Dow manufactures plastics, chemicals, and agricultural products. With a presence in about 160 countries, it employs about 54,000 people worldwide. Dow has been called the "chemical companies' chemical company," as its sales are to other industries rather than directly to end-use consumers. Dow is a member of the American Chemistry Council. In 2015, Dow and fellow chemical company DuPont agreed to a corporate reorganization which involved the merger and split of Dow and DuPont into three different companies. The plan commenced in 2017, when Dow and DuPont merged to form DowDuPont, and finalized in April 2019, as the materials science division was spunoff from DowDuPont and took the name of the Dow Chemical Company. History Early history Dow was founded in 189 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
