Waksman Institute Of Microbiology
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Waksman Institute Of Microbiology
The Waksman Institute of Microbiology is a research facility on the Busch Campus of Rutgers University. It is named after Selman Waksman, a student and then faculty member at Rutgers who won the Nobel Prize for Medicine in 1952 for research which led to the discovery of streptomycin. The institute conducts research on microbial molecular genetics, developmental molecular genetics, plant molecular genetics, and structural and computational biology. In 2019, Dr. Kenneth D. Irvine was appointed as Interim Director of the Waksman Institute. Dr. Irvine has been a member of the Waksman Institute since 1995 and is currently a Distinguished Professor of Molecular Biology and Biochemistry and Director of the Rutgers Graduate Program in Cell and Developmental Biology. He was selected by his peers after the untimely passing of the Institute's fourth director, Joachim Messing. History A total of eighteen antibiotics were isolated in Waksman's laboratory at the New Jersey Agriculture Exper ...
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Busch Campus (Rutgers University)
Busch Campus is one of the five sub-campuses at Rutgers University's New Brunswick/Piscataway area campus, and is located entirely within Piscataway, New Jersey, US. Academic facilities and departments centered on this campus are primarily those related to the natural sciences: physics, pharmacy, engineering, psychology, mathematics and statistics, chemistry, geology, and biology. The Rutgers Medical School was also built on this campus in 1970, but a year later was separated by the state, renamed the Robert Wood Johnson Medical School, and merge with the New Jersey Medical School and other health profession schools in Newark and New Brunswick to create the College of Medicine and Dentistry of New Jersey. Rutgers and the medical school continued to share the land and facilities on the campus in a slightly irregular arrangement. On July 1, 2013, Robert Wood Johnson Medical School was officially merged back into Rutgers University, along with most of the other schools of UMDNJ, with ...
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Rutgers University
Rutgers University (; RU), officially Rutgers, The State University of New Jersey, is a Public university, public land-grant research university consisting of four campuses in New Jersey. Chartered in 1766, Rutgers was originally called Queen's College, and was affiliated with the Reformed Church in America, Dutch Reformed Church. It is the eighth-oldest college in the United States, the second-oldest in New Jersey (after Princeton University), and one of the nine U.S. colonial colleges that were chartered before the American Revolution.Stoeckel, Althea"Presidents, professors, and politics: the colonial colleges and the American revolution", ''Conspectus of History'' (1976) 1(3):45–56. In 1825, Queen's College was renamed Rutgers College in honor of Colonel Henry Rutgers, whose substantial gift to the school had stabilized its finances during a period of uncertainty. For most of its existence, Rutgers was a Private university, private liberal arts college but it has evolved int ...
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Selman Waksman
Selman Abraham Waksman (July 22, 1888 – August 16, 1973) was a Jewish Russian-born American inventor, Nobel Prize laureate, biochemist and microbiologist whose research into the decomposition of organisms that live in soil enabled the discovery of streptomycin and several other antibiotics. A professor of biochemistry and microbiology at Rutgers University for four decades, he discovered a number of antibiotics (and introduced the modern sense of that word to name them), and he introduced procedures that have led to the development of many others. The proceeds earned from the licensing of his patents funded a foundation for microbiological research, which established the Waksman Institute of Microbiology located on the Rutgers University Busch Campus in Piscataway, New Jersey (USA). In 1952, he was awarded the Nobel Prize in Physiology or Medicine for "ingenious, systematic and successful studies of the soil microbes that led to the discovery of streptomycin." Waksman and his ...
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Nobel Prize For Medicine
The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according to Alfred Nobel's 1895 will, are awarded "to those who, during the preceding year, have conferred the greatest benefit to humankind". Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace. The Nobel Prize is presented annually on the anniversary of Alfred Nobel's death, 10 December. As of 2022, 114 Nobel Prizes in Physiology or Medicine have been awarded to 226 laureates, 214 men and 12 women. The first one was awarded in 1901 to the German physiologist, Emil von Behring, for his work on serum therapy and the development of a vaccine against diphtheria. The first woman to receive the Nobel Prize in Physiology or Medicine, Gerty Cori, received it in 1947 for her role in elucidating the ...
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Streptomycin
Streptomycin is an antibiotic medication used to treat a number of bacterial infections, including tuberculosis, ''Mycobacterium avium'' complex, endocarditis, brucellosis, ''Burkholderia'' infection, plague, tularemia, and rat bite fever. For active tuberculosis it is often given together with isoniazid, rifampicin, and pyrazinamide. It is administered by injection into a vein or muscle. Common side effects include vertigo, vomiting, numbness of the face, fever, and rash. Use during pregnancy may result in permanent deafness in the developing baby. Use appears to be safe while breastfeeding. It is not recommended in people with myasthenia gravis or other neuromuscular disorders. Streptomycin is an aminoglycoside. It works by blocking the ability of 30S ribosomal subunits to make proteins, which results in bacterial death. Albert Schatz first isolated streptomycin in 1943 from ''Streptomyces griseus''. It is on the World Health Organization's List of Essential Medicine ...
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Molecular Genetics
Molecular genetics is a sub-field of biology that addresses how differences in the structures or expression of DNA molecules manifests as variation among organisms. Molecular genetics often applies an "investigative approach" to determine the structure and/or function of genes in an organism's genome using genetic screens.  The field of study is based on the merging of several sub-fields in biology: classical Mendelian inheritance, Cell biology, cellular biology, molecular biology, biochemistry, and biotechnology. Researchers search for mutations in a gene or induce mutations in a gene to link a gene sequence to a specific phenotype. Molecular genetics is a powerful methodology for linking mutations to genetic conditions that may aid the search for treatments/cures for various genetics diseases. History For molecular genetics to develop as a discipline, several scientific discoveries were necessary.  The discovery of DNA as a means to transfer the genetic code of life f ...
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Computational Biology
Computational biology refers to the use of data analysis, mathematical modeling and computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and big data, the field also has foundations in applied mathematics, chemistry, and genetics. It differs from biological computing, a subfield of computer engineering which uses bioengineering to build computers. History Bioinformatics, the analysis of informatics processes in biological systems, began in the early 1970s. At this time, research in artificial intelligence was using network models of the human brain in order to generate new algorithms. This use of biological data pushed biological researchers to use computers to evaluate and compare large data sets in their own field. By 1982, researchers shared information via punch cards. The amount of data grew exponentially by the end of the 1980s, requiring new computational methods for quickly interpreting ...
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Kenneth D
Kenneth is an English given name and surname. The name is an Anglicised form of two entirely different Gaelic personal names: ''Cainnech'' and '' Cináed''. The modern Gaelic form of ''Cainnech'' is ''Coinneach''; the name was derived from a byname meaning "handsome", "comely". A short form of ''Kenneth'' is '' Ken''. Etymology The second part of the name ''Cinaed'' is derived either from the Celtic ''*aidhu'', meaning "fire", or else Brittonic ''jʉ:ð'' meaning "lord". People :''(see also Ken (name) Ken is a masculine given name of Scottish / Scottish Gaelic origin. It is used either as a given name or as a short form of names with the letters "Ken" (like Kenneth, Kenan, Kendrick, Kendall, Kennedy, Mackenzie, Kenson, or Kenelm). Ken is a ... and Kenny)'' Places In the United States: * Kenneth, Indiana * Kenneth, Minnesota * Kenneth City, Florida In Scotland: * Inch Kenneth, an island off the west coast of the Isle of Mull Other * "What's the Frequency, Kenneth?", a ...
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Joachim Messing
Joachim Wilhelm "Jo" Messing (September 10, 1946 – September 13, 2019) was a German-American biologist who was a professor of molecular biology and the fourth director of the Waksman Institute of Microbiology at Rutgers University. Upon his arrival at Rutgers in 1985, Jo Messing initiated research activity on computational and structural biology and further emphasis on molecular genetics of the regulation of gene expression and biomolecular interactions. In the eighties, he provided incubator space for two Biotechnology centers at Rutgers, one in Medicine and one in Agriculture. Subsequently, he also founded two new departments at Rutgers and served as the first chair, the Department of Molecular Biology and Biochemistry and the Department of Genetics. Messing was also involved in the Plant Genome Initiative at Rutgers, which has contributed to the sequencing of the maize, sorghum, and the rice genome. Besides maize, sorghum, and rice, they have also contributed to the sequenci ...
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Neomycin
Neomycin is an aminoglycoside antibiotic that displays bactericidal activity against gram-negative aerobic bacilli and some anaerobic bacilli where resistance has not yet arisen. It is generally not effective against gram-positive bacilli and anaerobic gram-negative bacilli. Neomycin comes in oral and topical formulations, including creams, ointments, and eyedrops. Neomycin belongs to the aminoglycoside class of antibiotics that contain two or more amino sugars connected by glycosidic bonds. Neomycin was discovered in 1949 by microbiologist Selman Waksman and his student Hubert Lechevalier at Rutgers University. Neomycin received approval for medical use in 1952. Rutgers University was granted the patent for neomycin in 1957. Discovery Neomycin was discovered in 1949 by the microbiologist Selman Waksman and his student Hubert Lechevalier at Rutgers University. It is produced naturally by the bacterium '' Streptomyces fradiae''. Synthesis requires specific nutrient conditions i ...
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