Wadsworth Center
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Wadsworth Center
The Wadsworth Center, located in Albany, New York, is the research-intensive public health laboratory of the New York State Department of Health. History The Wadsworth Center, originally the New York State's Antitoxin Laboratory, was established in 1901. Its mission was to standardize and manufacture antitoxin, which was for the treatment of communicable diseases such as diphtheria and anthrax. In 1914, the Antitoxin Laboratory was designated the Division of Laboratories and Research. At the same time, Augustus B. Wadsworth was named director and he served until 1945. In 1974, Enzo Paoletti joined the Wadsworth Center and with Dennis Panicali devised a strategy to produce DNA vaccines by using genetic engineering to transform ordinary smallpox vaccine into vaccines that may be able to prevent other diseases. In four seminal papers they provided the technology and proof of principle to construct vaccines using genetically engineered poxviruses, altering the DNA of cowpox virus by ...
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Empire State Plaza
The Governor Nelson A. Rockefeller Empire State Plaza (known commonly as the Empire State Plaza, and also as the South Mall) is a complex of several state government buildings in downtown Albany, New York. The complex was built between 1965 and 1976 at an estimated total cost of $2 billion. It houses several departments of the New York State administration and is integrated with the New York State Capitol, completed in 1899, which houses the state legislature. Among the offices at the plaza are the Department of Health and the Biggs Laboratory of the Wadsworth Center. The Empire State Art Collection, a major public collection of 1960s and 1970s monumental abstract artworks, is on permanent display throughout the site. The New York State Office of General Services maintains the plaza. The Nelson A. Rockefeller Empire State Plaza Performing Arts Center Corporation is a New York state public-benefit corporation that was created in 1979 to manage the performing arts facility in t ...
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Herpes Simplex Virus
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known by their taxonomical names ''Human alphaherpesvirus 1'' and '' Human alphaherpesvirus 2'', are two members of the human ''Herpesviridae'' family, a set of viruses that produce viral infections in the majority of humans. Both HSV-1 and HSV-2 are very common and contagious. They can be spread when an infected person begins shedding the virus. As of 2016, about 67% of the world population under the age of 50 had HSV-1. In the United States, about 47.8% and 11.9% are estimated to have HSV-1 and HSV-2, respectively, though actual prevalence may be much higher. Because it can be transmitted through any intimate contact, it is one of the most common sexually transmitted infections. Symptoms Many of those who are infected ''never'' develop symptoms. Symptoms, when they occur, may include watery blisters in the skin or mucous membranes of the mouth, lips, nose, genitals, or eyes (herpes simplex keratitis). Lesions heal with a ...
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Organizations Based In New York (state)
An organization or organisation (Commonwealth English; see spelling differences), is an entity—such as a company, an institution, or an association—comprising one or more people and having a particular purpose. The word is derived from the Greek word ''organon'', which means tool or instrument, musical instrument, and organ. Types There are a variety of legal types of organizations, including corporations, governments, non-governmental organizations, political organizations, international organizations, armed forces, charities, not-for-profit corporations, partnerships, cooperatives, and educational institutions, etc. A hybrid organization is a body that operates in both the public sector and the private sector simultaneously, fulfilling public duties and developing commercial market activities. A voluntary association is an organization consisting of volunteers. Such organizations may be able to operate without legal formalities, depending on jurisdiction, includ ...
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Research Institutes In New York (state)
Research is " creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, eco ...
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University At Albany, SUNY
The State University of New York at Albany, commonly referred to as the University at Albany, UAlbany or SUNY Albany, is a public research university with campuses in Albany, Rensselaer, and Guilderland, New York. Founded in 1844, it is one of the four "university centers" of the State University of New York (SUNY) system. The university enrolls 16,648 students in nine schools and colleges, which offer 50 undergraduate majors and 125 graduate degree programs. The university's academic choices include new and emerging fields in public policy, homeland security, globalization, documentary studies, biotechnology, and informatics. Through the UAlbany and SUNY-wide exchange programs, students have more than 600 study-abroad programs to choose from, as well as government and business internship opportunities in New York's capital and surrounding region. It is classified among "R1: Doctoral Universities – Very high research activity". The research enterprise totaled expenditur ...
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Guilderland, New York
Guilderland is a town in Albany County, New York, United States. In the 2020 census, the town had a population of 36,848. The town is named for the Gelderland province in the Netherlands. The town of Guilderland is on the central-northwest border of the county. It is just west of Albany, the capital of the U.S. state of New York. History Guilderland was originally a part of the Manor of Rensselaerswyck that Patroon Kiliaen van Rensselaer began in 1629 as part of the New Netherland colony. By the end of the 17th century, Dutch settlers from Albany and Schenectady began to establish farms in the area, beginning first along the banks of the Normans Kill. In 1712, a group of emigrants from the Rhine Valley in present-day Germany passed through the town on their way to Schoharie. They were the first to record and name the Helderberg Escarpment, originally Hellebergh meaning "bright or clear mountain". This name would also be used for all the land between the Normans Kill and ...
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Influenza
Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms begin from one to four days after exposure to the virus (typically two days) and last for about 2–8 days. Diarrhea and vomiting can occur, particularly in children. Influenza may progress to pneumonia, which can be caused by the virus or by a subsequent bacterial infection. Other complications of infection include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems such as asthma and cardiovascular disease. There are four types of influenza virus, termed influenza viruses A, B, C, and D. Aquatic birds are the primary source of Influenza A virus (IAV), which is also widespread in various mammals, including humans and pigs. Influenza B virus (IBV) and Influenza C virus (ICV) pri ...
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Hepatitis B
Hepatitis B is an infectious disease caused by the ''Hepatitis B virus'' (HBV) that affects the liver; it is a type of viral hepatitis. It can cause both acute and chronic infection. Many people have no symptoms during an initial infection. For others, symptoms may appear 30 to 180 days after becoming infected and can include a rapid onset of sickness with nausea, vomiting, yellowish skin, fatigue, dark urine, and abdominal pain. Symptoms during acute infection typically last for a few weeks, though some people may feel sick for up to six months. Deaths resulting from acute stage HBV infections are rare. An HBV infection lasting longer than six months is usually considered chronic. The likelihood of developing chronic hepatitis B is higher for those who are infected with HBV at a younger age. About 90% of those infected during or shortly after birth develop chronic hepatitis B, while less than 10% of those infected after the age of five develop chronic cases. Most of those wit ...
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Cowpox
Cowpox is an infectious disease caused by the ''cowpox virus'' (CPXV). It presents with large blisters in the skin, a fever and swollen glands, historically typically following contact with an infected cow, though in the last several decades more often (though overall rarely) from infected cats. The hands and face are most frequently affected and the spots are generally very painful. The virus, part of the genus '' Orthopoxvirus'', is closely related to the ''vaccinia'' virus. The virus is zoonotic, meaning that it is transferable between species, such as from cat to human. The transferral of the disease was first observed in dairymaids who touched the udders of infected cows and consequently developed the signature pustules on their hands.Vanessa Ngan, "Viral and Skin Infections"
2009
Cowpox is more com ...
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Albany, New York
Albany ( ) is the capital of the U.S. state of New York, also the seat and largest city of Albany County. Albany is on the west bank of the Hudson River, about south of its confluence with the Mohawk River, and about north of New York City. The city is known for its architecture, commerce, culture, institutions of higher education, and rich history. It is the economic and cultural core of the Capital District of the State of New York, which comprises the Albany–Schenectady–Troy Metropolitan Statistical Area, including the nearby cities and suburbs of Troy, Schenectady, and Saratoga Springs. With an estimated population of 1.1 million in 2013, the Capital District is the third most populous metropolitan region in the state. As of 2020, Albany's population was 99,224. The Hudson River area was originally inhabited by Algonquian-speaking Mohican (Mahican), who called it ''Pempotowwuthut-Muhhcanneuw''. The area was settled by Dutch colonists who, in 1614, built Fort ...
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Poxviruses
''Poxviridae'' is a family of double-stranded DNA viruses. Vertebrates and arthropods serve as natural hosts. There are currently 83 species in this family, divided among 22 genera, which are divided into two subfamilies. Diseases associated with this family include smallpox. Four genera of poxviruses may infect humans: ''Orthopoxvirus'', ''Parapoxvirus'', ''Yatapoxvirus'', ''Molluscipoxvirus''. ''Orthopoxvirus'': smallpox virus (variola), vaccinia virus, cowpox virus, monkeypox virus; ''Parapoxvirus'': orf virus, pseudocowpox, bovine papular stomatitis virus; ''Yatapoxvirus'': tanapox virus, yaba monkey tumor virus; ''Molluscipoxvirus'': molluscum contagiosum virus (MCV). The most common are vaccinia (seen on the Indian subcontinent) and molluscum contagiosum, but monkeypox infections are rising (seen in west and central African rainforest countries). The similarly named disease chickenpox is not a true poxvirus and is caused by the herpesvirus varicella zoster. Etymology ...
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Smallpox Vaccine
The smallpox vaccine is the first vaccine to be developed against a contagious disease. In 1796, British physician Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox virus. Cowpox served as a natural vaccine until the modern smallpox vaccine emerged in the 20th century. From 1958 to 1977, the World Health Organization (WHO) conducted a global vaccination campaign that eradicated smallpox, making it the only human disease to be eradicated. Although routine smallpox vaccination is no longer performed on the general public, the vaccine is still being produced to guard against bioterrorism, biological warfare, and monkeypox.Anderson MG, Frenkel LD, Homann S, and Guffey J. (2003), "A case of severe monkeypox virus disease in an American child: emerging infections and changing professional values"; '' Pediatr Infect Dis J'';22(12): 1093–96; discussion 1096–98. The term ''vaccine'' derives from the Latin ...
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