Wade-Dahl-Till Valve
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Wade-Dahl-Till Valve
The Wade-Dahl-Till (WDT) valve is a cerebral shunt developed in 1962 by hydraulic engineer Stanley Wade, author Roald Dahl, and neurosurgeon Kenneth Till. In 1960, Dahl's son Theo developed hydrocephalus after being struck by a taxicab. A standard Holter shunt was installed to drain excess fluid from his brain. However, the shunt jammed too often, causing pain and blindness, risking brain damage and requiring emergency surgery. Till, a neurosurgeon at London's Great Ormond Street Hospital for children, determined that debris accumulated in the hydrocephalic ventricles could clog the slits in the Holter valves, especially with patients such as Theo who had bad bleeding in the brain and brain damage. Dahl knew Wade to be an expert in precision hydraulic engineering, from their shared hobby of flying model aircraft. (In addition to building his own model aircraft engines, Wade ran a factory at High Wycombe for producing precision hydraulic pumps.) With Dahl coordinating the efforts ...
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Wade-Dahl-Till Valve (from Patent Application)
The Wade-Dahl-Till (WDT) valve is a cerebral shunt developed in 1962 by hydraulic engineer Stanley Wade, author Roald Dahl, and neurosurgeon Kenneth Till. In 1960, Dahl's son Theo developed hydrocephalus after being struck by a taxicab. A standard Holter shunt was installed to drain excess fluid from his brain. However, the shunt jammed too often, causing pain and blindness, risking brain damage and requiring emergency surgery. Till, a neurosurgeon at London's Great Ormond Street Hospital for children, determined that debris accumulated in the hydrocephalic ventricles could clog the slits in the Holter valves, especially with patients such as Theo who had bad bleeding in the brain and brain damage. Dahl knew Wade to be an expert in precision hydraulic engineering, from their shared hobby of flying model aircraft. (In addition to building his own model aircraft engines, Wade ran a factory at High Wycombe for producing precision hydraulic pumps.) With Dahl coordinating the efforts ...
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Cerebral Shunt
A cerebral shunt is a device permanently implanted inside the head and body to drain excess fluid away from the brain. They are commonly used to treat hydrocephalus, the swelling of the brain due to excess buildup of cerebrospinal fluid (CSF). If left unchecked, the excess CSF can lead to an increase in intracranial pressure (ICP), which can cause intracranial hematoma, cerebral edema, crushed brain tissue or herniation. The drainage provided by a shunt can alleviate or prevent these problems in patients with hydrocephalus or related diseases. Shunts come in a variety of forms, but most of them consist of a valve housing connected to a catheter, the lower end of which is usually placed in the peritoneal cavity. The main differences between shunts are usually in the materials used to construct them, the types of valve (if any) used, and whether the valve is programmable or not. Description Valves types Shunt location The location of the shunt is determined by the neurosurg ...
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Roald Dahl
Roald Dahl (13 September 1916 – 23 November 1990) was a British novelist, short-story writer, poet, screenwriter, and wartime fighter ace of Norwegian descent. His books have sold more than 250 million copies worldwide. Dahl has been called "one of the greatest storytellers for children of the 20th century". Dahl was born in Wales to affluent Norwegian immigrant parents, and spent most of his life in England. He served in the Royal Air Force (RAF) during the Second World War. He became a fighter pilot and, subsequently, an intelligence officer, rising to the rank of acting wing commander. He rose to prominence as a writer in the 1940s with works for children and for adults, and he became one of the world's best-selling authors. His awards for contribution to literature include the 1983 World Fantasy Award for Life Achievement and the British Book Awards' Children's Author of the Year in 1990. Dahl and his work have been criticised for racial stereotypes, misogyny a ...
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Hydrocephalus
Hydrocephalus is a condition in which an accumulation of cerebrospinal fluid (CSF) occurs within the brain. This typically causes increased intracranial pressure, pressure inside the skull. Older people may have headaches, double vision, poor balance, urinary incontinence, personality changes, or mental impairment. In babies, it may be seen as a rapid increase in head size. Other symptoms may include vomiting, sleepiness, seizures, and Parinaud's syndrome, downward pointing of the eyes. Hydrocephalus can occur due to birth defects or be acquired later in life. Associated birth defects include neural tube defects and those that result in aqueductal stenosis. Other causes include meningitis, brain tumors, traumatic brain injury, intraventricular hemorrhage, and subarachnoid hemorrhage. The four types of hydrocephalus are communicating, noncommunicating, ''ex vacuo'', and normal pressure hydrocephalus, normal pressure. Diagnosis is typically made by physical examination and medic ...
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Holter Shunt
Holter may refer to: * Holter monitor In medicine, a Holter monitor (often simply Holter) is a type of ambulatory electrocardiography device, a portable device for cardiac monitoring (the monitoring of the electrical activity of the cardiovascular system) for at least 24 hours. T ...,ambulatory health monitor * Holter (surname) {{Disamb ...
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Great Ormond Street Hospital
Great Ormond Street Hospital (informally GOSH or Great Ormond Street, formerly the Hospital for Sick Children) is a children's hospital located in the Bloomsbury area of the London Borough of Camden, and a part of Great Ormond Street Hospital for Children NHS Foundation Trust. The hospital is the largest centre for child heart surgery in the UK and one of the largest centres for heart transplantation in the world. In 1962 they developed the first heart and lung bypass machine for children. With children's book author Roald Dahl, they developed an improved shunt valve for children with hydrocephalus, and non-invasive (percutaneous) heart valve replacements. They did the first UK clinical trials of the rubella vaccine, and the first bone marrow transplant and gene therapy for severe combined immunodeficiency.Breakthroughs It is closely associated with University College London (UCL) and in partnership with the UCL Great Ormond Street Institute of Child Health, which is adjace ...
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Ventricular System
The ventricular system is a set of four interconnected cavities known as cerebral ventricles in the brain. Within each ventricle is a region of choroid plexus which produces the circulating cerebrospinal fluid (CSF). The ventricular system is continuous with the central canal of the spinal cord from the fourth ventricle, allowing for the flow of CSF to circulate. All of the ventricular system and the central canal of the spinal cord are lined with ependyma, a specialised form of epithelium connected by tight junctions that make up the blood–cerebrospinal fluid barrier. Structure The system comprises four ventricles: * lateral ventricles right and left (one for each hemisphere) * third ventricle * fourth ventricle There are several foramina, openings acting as channels, that connect the ventricles. The interventricular foramina (also called the foramina of Monro) connect the lateral ventricles to the third ventricle through which the cerebrospinal fluid can flow. Ventric ...
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Model Aircraft
A model aircraft is a small unmanned aircraft. Many are replicas of real aircraft. Model aircraft are divided into two basic groups: flying and non-flying. Non-flying models are also termed static, display, or shelf models. Aircraft manufacturers and researchers make wind tunnel models for testing aerodynamic properties, for basic research, or for the development of new designs. Sometimes only part of the aircraft is modelled. Static models range from mass-produced toys in white metal or plastic to highly accurate and detailed models produced for museum display and requiring thousands of hours of work. Many are available in kits, typically made of injection-moulded polystyrene or resin. Flying models range from simple toy gliders made of sheets of paper, balsa, card stock or foam polystyrene to powered scale models built up from balsa, bamboo sticks, plastic, (including both moulded or sheet polystyrene, and styrofoam), metal, synthetic resin, either alone or with carbon fibr ...
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High Wycombe
High Wycombe, often referred to as Wycombe ( ), is a market town in Buckinghamshire, England. Lying in the valley of the River Wye surrounded by the Chiltern Hills, it is west-northwest of Charing Cross in London, south-southeast of Aylesbury, southeast of Oxford, northeast of Reading and north of Maidenhead. According to the 2021 United Kingdom census, High Wycombe's built up area has a population of 127,856, making it the second largest town in the ceremonial county of Buckinghamshire after Milton Keynes. The High Wycombe Urban Area, the conurbation of which the town is the largest component, has a population of 140,684. High Wycombe is mostly an unparished area. Part of the urban area constitutes the civil parish of Chepping Wycombe, which had a population of 14,455 according to the 2001 census – this parish represents that part of the ancient parish of Chepping Wycombe which was outside the former municipal borough of Wycombe. There has been a market he ...
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The Lancet
''The Lancet'' is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also the world's highest-impact academic journal. It was founded in England in 1823. The journal publishes original research articles, review articles ("seminars" and "reviews"), editorials, book reviews, correspondence, as well as news features and case reports. ''The Lancet'' has been owned by Elsevier since 1991, and its editor-in-chief since 1995 has been Richard Horton. The journal has editorial offices in London, New York City, and Beijing. History ''The Lancet'' was founded in 1823 by Thomas Wakley, an English surgeon who named it after the surgical instrument called a lancet (scalpel). Members of the Wakley family retained editorship of the journal until 1908. In 1921, ''The Lancet'' was acquired by Hodder & Stoughton. Elsevier acquired ''The Lancet'' from Hodder & Stoughton in 1991. Impact According to the ''Journal Citation Reports'', the journal has a 202 ...
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Implants (medicine)
Implant can refer to: Medicine *Implant (medicine), or specifically: **Brain implant **Breast implant **Buttock implant **Cochlear implant **Contraceptive implant **Dental implant **Fetal tissue implant **Implantable cardioverter-defibrillator **Orthopedic implant **Prosthetic implant **Retinal implant **Subdermal implant **Transdermal implant Alternative *Alien implants *Extraocular implant *Implant (body modification) * Implant (thought insertion) *Microchip implant (animal) (human) *''The Implant'', a television episode of ''Seinfeld'' See also *History of dental treatments *Implantation (other) *Osseointegration Osseointegration (from Latin ''osseus'' " bony" and ''integrare'' "to make whole") is the direct structural and functional connection between living bone and the surface of a load-bearing artificial implant ("load-bearing" as defined by Albrekt ... * Osseoincorporation {{disambig ...
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