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Wuzhishan Pig
The Wuzhishan pig is a breed of inbred miniature pig created by Professor Feng Shutang to be used as a model animal for medical research. Physical description The Wuzhishan pig grows up to a size of 50-70 cm (19.7-27.5 inches) long, and up to 30-35 kilograms in weight. They have a black head and back, and pink legs and bellies. Additionally, the Wuzhishan pig is often used to study the cardiovascular system in humans, due to the similarity of the pig's organs to those of a human. Genetic research The full genome sequence and analysis was completed by BGI Group in 2012; the breed was successfully identified in early 2013. The intellectual property rights for the breed are protected by both Chinese and American patents. On May 18, 2015, the Chinese Academy of Agricultural Sciences announced that its Institute of Animal Science had agreed to transfer all breeding research to Beijing Grand Life Science & Technology Co., Ltd., which has the sole rights to breed and sell Wuz ...
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Inbreeding
Inbreeding is the production of offspring from the mating or breeding of individuals or organisms that are closely related genetically. By analogy, the term is used in human reproduction, but more commonly refers to the genetic disorders and other consequences that may arise from expression of deleterious or recessive traits resulting from incestuous sexual relationships and consanguinity. Animals avoid incest only rarely. Inbreeding results in homozygosity, which can increase the chances of offspring being affected by recessive traits. In extreme cases, this usually leads to at least temporarily decreased biological fitness of a population (called inbreeding depression), which is its ability to survive and reproduce. An individual who inherits such deleterious traits is colloquially referred to as ''inbred''. The avoidance of expression of such deleterious recessive alleles caused by inbreeding, via inbreeding avoidance mechanisms, is the main selective reason for outcrossin ...
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Embryo
An embryo is an initial stage of development of a multicellular organism. In organisms that reproduce sexually, embryonic development is the part of the life cycle that begins just after fertilization of the female egg cell by the male sperm cell. The resulting fusion of these two cells produces a single-celled zygote that undergoes many cell divisions that produce cells known as blastomeres. The blastomeres are arranged as a solid ball that when reaching a certain size, called a morula, takes in fluid to create a cavity called a blastocoel. The structure is then termed a blastula, or a blastocyst in mammals. The mammalian blastocyst hatches before implantating into the endometrial lining of the womb. Once implanted the embryo will continue its development through the next stages of gastrulation, neurulation, and organogenesis. Gastrulation is the formation of the three germ layers that will form all of the different parts of the body. Neurulation forms the nervous ...
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Pig Breeds Originating In China
The pig (''Sus domesticus''), often called swine, hog, or domestic pig when distinguishing from other members of the genus '' Sus'', is an omnivorous, domesticated, even-toed, hoofed mammal. It is variously considered a subspecies of ''Sus scrofa'' (the wild boar or Eurasian boar) or a distinct species. The pig's head-plus-body length ranges from , and adult pigs typically weigh between , with well-fed individuals even exceeding this range. The size and weight of hogs largely depends on their breed. Compared to other artiodactyls, a pig's head is relatively long and pointed. Most even-toed ungulates are herbivorous, but pigs are omnivores, like their wild relative. Pigs grunt and make snorting sounds. When used as livestock, pigs are farmed primarily for the production of meat, called pork. A group of pigs is called a ''passel'', a ''team'', or a ''sounder''. The animal's bones, hide, and bristles are also used in products. Pigs, especially miniature breeds, are kept as pets ...
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Ministry Of Science And Technology (China)
The Ministry of Science and Technology of the People's Republic of China, formerly the State Science and Technology Commission, is the central government ministry which coordinates science and technology activities in the country. The office is located in Xicheng District, Beijing. The ministry is responsible for formulating guidelines and related policies for science and technology in China development and promoting basic and special research on science and technology. The Ministry develop human resources, including introducing foreign intellectual planning and organising international scientific and technological cooperation and talent exchanges and strengthening China's innovation capabilities in the field of international scientific research. History of ministry The predecessor of MOST was the National Technical Committee established at the 28th Plenary Session of the State Council in 1956 and was renamed as the Ministry of Science and Technology of the People's Republic ...
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Xenotransplantation
Xenotransplantation (''xenos-'' from the Greek meaning "foreign" or strange), or heterologous transplant, is the transplantation of living cells, tissues or organs from one species to another. Such cells, tissues or organs are called xenografts or xenotransplants. It is contrasted with allotransplantation (from other individual of same species), syngeneic transplantation or isotransplantation (grafts transplanted between two genetically identical individuals of the same species) and autotransplantation (from one part of the body to another in the same person). Xenotransplantation of human tumor cells into immunocompromised mice is a research technique frequently used in pre-clinical oncology research. Human xenotransplantation offers a potential treatment for end-stage organ failure, a significant health problem in parts of the industrialized world. It also raises many novel medical, legal and ethical issues. A continuing concern is that many animals, such as pigs, have a s ...
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Virology
Virology is the Scientific method, scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host (biology), host cell (biology), cells for reproduction, their interaction with host organism physiology and immunity, the diseases they cause, the techniques to isolate and culture them, and their use in research and therapy. The identification of the causative agent of tobacco mosaic disease (TMV) as a novel pathogen by Martinus Beijerinck (1898) is now acknowledged as being the history of virology, official beginning of the field of virology as a discipline distinct from bacteriology. He realized the source was neither a bacterial nor a fungal infection, but something completely different. Beijerinck used the word "virus" to describe the mysterious agent in his 'contagium vivum fluidum' ('contagious living fluid'). Rosalind Franklin proposed the f ...
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Academy Of Military Medical Sciences
The Academy of Military Medical Sciences (AMMS) of the PLA Academy of Military Science () is a Chinese military medical research institute. It was established in Shanghai in 1951. It has been based in Beijing since 1958. In October 2011 the drug " Night Eagle", developed to help soldiers cope with sleep deprivation during missions, was unveiled in an exhibition marking the institute's 60th anniversary. In December 2014, the Chinese government announced that the Academy of Military Medical Sciences had developed an Ebola virus vaccine candidate that had been approved for clinical trials. In December 2021, the United States Department of Commerce added the Academy of Military Medical Sciences to the Entity List, accusing it of aiding in the Uyghur genocide. COVID-19 vaccine During the COVID-19 pandemic, the AMMS partnered with CanSino Biologics to develop Convidecia. The development team, led by Chen Wei, registered a Phase 1 trial in March 2020 and a Phase 2 trial in April ...
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Pancreatic Islets
The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans. The pancreatic islets constitute 1–2% of the pancreas volume and receive 10–15% of its blood flow. The pancreatic islets are arranged in density routes throughout the human pancreas, and are important in the metabolism of glucose. Structure There are about 1 million islets distributed throughout the pancreas of a healthy adult human, each of which measures an average of about 0.2 mm in diameter.:928 Each islet is separated from the surrounding pancreatic tissue by a thin fibrous connective tissue capsule which is continuous with the fibrous connective tissue that is interwoven throughout the rest of the pancreas.:928 Microanatomy Hormones produced in the pancreatic islets are secreted directly into the blood flow by (at least) five types of cells. In rat islets, endocrin ...
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Blastocyst
The blastocyst is a structure formed in the early embryonic development of mammals. It possesses an inner cell mass (ICM) also known as the ''embryoblast'' which subsequently forms the embryo, and an outer layer of trophoblast cells called the trophectoderm. This layer surrounds the inner cell mass and a fluid-filled cavity known as the blastocoel. In the late blastocyst the trophectoderm is known as the trophoblast. The trophoblast gives rise to the chorion and amnion, the two fetal membranes that surround the embryo. The placenta derives from the embryonic chorion (the portion of the chorion that develops villi) and the underlying uterine tissue of the mother. The name "blastocyst" arises from the Greek ' ("a sprout") and ' ("bladder, capsule"). In other animals this is a structure consisting of an undifferentiated ball of cells and is called a blastula. In humans, blastocyst formation begins about five days after fertilization when a fluid-filled cavity opens up in the mor ...
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Germ Cell
Germ or germs may refer to: Science * Germ (microorganism), an informal word for a pathogen * Germ cell, cell that gives rise to the gametes of an organism that reproduces sexually * Germ layer, a primary layer of cells that forms during embryonic development * Cereal germ, the reproductive part of a cereal grain * Tooth germ, an aggregation of cells that eventually forms a tooth * Germ theory of disease, which states that some diseases are caused by microorganisms * Germ (mathematics), an object in a topological space that captures local properties Art and media Music * Germs (band), an American punk rock band * Germ (musician), a stage name of Tim Wright * Germ (rapper), an American rapper affiliated with Suicideboys and Pouya * "Germs" (song), by "Weird Al" Yankovic * ''The Germ'' (album), by Victim's Family Others * "Germs" (''Invader Zim''), an episode of ''Invader Zim'' * ''The Germ'' (periodical), a British art magazine published in 1850 * The Germs (comics) ...
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Life Science
Life is a quality that distinguishes matter that has biological processes, such as signaling and self-sustaining processes, from that which does not, and is defined by the capacity for growth, reaction to stimuli, metabolism, energy transformation, and reproduction. Various forms of life exist, such as plants, animals, fungi, protists, archaea, and bacteria. Biology is the science that studies life. The gene is the unit of heredity, whereas the cell is the structural and functional unit of life. There are two kinds of cells, prokaryotic and eukaryotic, both of which consist of cytoplasm enclosed within a membrane and contain many biomolecules such as proteins and nucleic acids. Cells reproduce through a process of cell division, in which the parent cell divides into two or more daughter cells and passes its genes onto a new generation, sometimes producing genetic variation. Organisms, or the individual entities of life, are generally thought to be open systems ...
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Miniature Pig
Miniature Pigs, also called mini pig, or Pygmy pig, are small breeds of domestic pig, such as the Vietnamese Pot-Bellied pig, Göttingen minipig, Juliana pig, Choctaw hog, or Kunekune (and specimens derived by crossbreeding these breeds). Miniature pigs can usually be distinguished from other pigs by their pot belly, a swayed back, a chubby figure, a rounded head, a short snout, short legs, a short neck, and a tail with thick hair at the end. Typically, miniature pigs will range in weight from about to . History In the 1960s, Chinese pigs that grew to be were sent to zoos in Western cities and were used for medical research in the fields of toxicology, pharmacology, pulmonology, cardiology, aging, and as a source of organs for organ transplantation. These comparatively smaller pigs were easier to work with than larger pig breeds, which typically reach weights of . In the mid-1980s, Keith Connell of the Bowmanville Zoo in Ontario imported breeding Vietnamese Pot-Bellied pi ...
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