|
Wilson's Heart (House)
"Wilson's Heart" is the sixteenth episode and season finale of the fourth season of ''House'' and the eighty-sixth episode overall. It aired on May 19, 2008, on Fox. It is the second and final part of the two-part fourth season finale, the first part being "House's Head". Plot In the second part of the two-part season finale, House remains affected by injuries sustained in a bus crash that has also left Amber Volakis rapidly deteriorating from a mysterious condition. Clues inside House's head hold the key to Amber's condition, and House's friendship with Wilson is tested as murky memories from the bus accident threaten to change their lives forever. The episode begins with House and Wilson at Princeton General Hospital, where the eight overflow victims of the bus crash that weren't taken to Princeton-Plainsboro ended up being taken, including Amber, who up until now was only known as Jane Doe #2 due to a lack of ID on her. The attending physician at Princeton General cannot ex ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
House (TV Series)
''House'' (also called ''House, M.D.'') is an American medical drama television series that originally ran on the Fox network for eight seasons, from November 16, 2004, to May 21, 2012. The series' main character is Dr. Gregory House (Hugh Laurie), an unconventional, misanthropic medical genius who, despite his dependence on pain medication, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital (PPTH) in New Jersey. The series' premise originated with Paul Attanasio, while David Shore, who is credited as creator, was primarily responsible for the conception of the title character. The series' executive producers included Shore, Attanasio, Attanasio's business partner Katie Jacobs, and film director Bryan Singer. It was filmed largely in a neighborhood and business district in Los Angeles County's Westside called Century City. The show received high critical acclaim, and was consistently one of the highest rated series in the United States. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxidative Stress
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily Detoxification, detoxify the reactive intermediates or to repair the resulting damage. Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. Oxidative stress from Cellular respiration, oxidative metabolism causes base damage, as well as DNA damage (naturally occurring), strand breaks in DNA. Base damage is mostly indirect and caused by the reactive oxygen species generated, e.g., O2− (superoxide radical), OH (hydroxyl radical) and H2O2 (hydrogen peroxide). Further, some reactive oxidative species act as cellular messengers in redox signaling. Thus, oxidative stress can cause disruptions in normal mechanisms of cellular signaling. In humans, oxidative stress is thought to be involved in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
José González (singer)
José Gabriel González (born 31 July 1978) is a Swedish indie folk singer-songwriter and guitarist from Gothenburg. González is also a member of the band Junip, along with Tobias Winterkorn. Early life and education The González family – made up of González's father, a National University of San Luis psychology student, González's mother, a fellow student studying biochemistry, both of whom were politically active, and González's older sister, then an infant – fled Argentina after the military coup d'état in March 1976, at the start of the "Dirty War". Escaping to Brazil, they were granted asylum by the Swedish consulate in Rio de Janeiro, and relocated to Gothenburg in 1977. José was born a year later, in the Haga district of Gothenburg. He has a younger sibling. He commented, "It's a very small town. It has about a half-million people living there. It's a pretty good music city by the ocean. It rains a lot there, but it's beautiful in the summertime." González ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Teardrop (Massive Attack Song)
"Teardrop" (also formatted as "Tear Drop") is a song by English trip hop group Massive Attack. Vocals are performed by Elizabeth Fraser, former lead singer of Cocteau Twins, who also wrote the lyrics. It was released on 27 April 1998 as the second single from the group's third studio album, ''Mezzanine'' (1998). A harpsichord-driven track, "Teardrop" was originally set to feature vocals from Madonna, whom Massive Attack turned down in favour of Fraser. In the United Kingdom, "Teardrop" peaked at number 10, becoming the group's highest-charting single and only top-ten hit in their native country. It reached number one in Iceland and became a top-twenty hit in Australia, Ireland, and New Zealand, as well as in Denmark in 2012. The music video, directed by Walter Stern, features a foetus singing in the womb, and the song has been featured in various television programmes, including as the opening theme for the U.S. television show ''House''. Development "Teardrop" was first deve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Massive Attack
Massive Attack are an English trip hop collective formed in 1988 in Bristol by Robert "3D" Del Naja, Adrian "Tricky" Thaws, Andrew "Mushroom" Vowles and Grant "Daddy G" Marshall. The debut Massive Attack album ''Blue Lines'' was released in 1991, with the single "Unfinished Sympathy" reaching the charts and later being voted the 63rd greatest song of all time in a poll by ''NME''. 1998's ''Mezzanine'' (containing the top 10 single " Teardrop") and 2003's '' 100th Window'' charted in the UK at number one. Both ''Blue Lines'' and ''Mezzanine'' feature in ''Rolling Stone''s list of the 500 Greatest Albums of All Time. The group has won numerous music awards throughout their career, including a Brit Award—winning Best British Dance Act, two MTV Europe Music Awards, and two Q Awards. They have released five studio albums that have sold over 13 million copies worldwide. Throughout their history, Massive Attack have been supporters and activists for political, human rights a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Huntington's Disease
Huntington's disease (HD), also known as Huntington's chorea, is a neurodegenerative disease that is mostly inherited. The earliest symptoms are often subtle problems with mood or mental abilities. A general lack of coordination and an unsteady gait often follow. It is also a basal ganglia disease causing a hyperkinetic movement disorder known as chorea. As the disease advances, uncoordinated, involuntary body movements of chorea become more apparent. Physical abilities gradually worsen until coordinated movement becomes difficult and the person is unable to talk. Mental abilities generally decline into dementia. The specific symptoms vary somewhat between people. Symptoms usually begin between 30 and 50 years of age but can start at any age. The disease may develop earlier in each successive generation. About eight percent of cases start before the age of 20 years, and are known as ''juvenile HD'', which typically present with the slow movement symptoms of Parkinson's d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thirteen (House)
Remy "Thirteen" Hadley, M.D., is a fictional character on the Fox medical drama ''House'', portrayed by Olivia Wilde. She is part of the new diagnostic team assembled by Dr. Gregory House after the disbanding of his previous team in the third-season finale. The character's nickname derives from the episode " The Right Stuff", when she is assigned the number during a competition for her position at the Princeton-Plainsboro Teaching Hospital. The show depicts Thirteen as a secretive character who does not divulge personal information; her surname was not used on the show until the fourth season's penultimate episode "House's Head", nor her given name until the fifth-season episode "Emancipation". Instead, several of the character's traits are implied before they are depicted as true. In the season four episode "You Don't Want to Know", Thirteen tells House that her mother died from Huntington's disease; a test she performs several episodes later confirms she carries the gene. Aft ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heart
The heart is a muscular organ in most animals. This organ pumps blood through the blood vessels of the circulatory system. The pumped blood carries oxygen and nutrients to the body, while carrying metabolic waste such as carbon dioxide to the lungs. In humans, the heart is approximately the size of a closed fist and is located between the lungs, in the middle compartment of the chest. In humans, other mammals, and birds, the heart is divided into four chambers: upper left and right atria and lower left and right ventricles. Commonly the right atrium and ventricle are referred together as the right heart and their left counterparts as the left heart. Fish, in contrast, have two chambers, an atrium and a ventricle, while most reptiles have three chambers. In a healthy heart blood flows one way through the heart due to heart valves, which prevent backflow. The heart is enclosed in a protective sac, the pericardium, which also contains a small amount of fluid. The wall ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coma
A coma is a deep state of prolonged unconsciousness in which a person cannot be awakened, fails to respond normally to painful stimuli, light, or sound, lacks a normal wake-sleep cycle and does not initiate voluntary actions. Coma patients exhibit a complete absence of wakefulness and are unable to consciously feel, speak or move. Comas can be derived by natural causes, or can be medically induced. Clinically, a coma can be defined as the inability consistently to follow a one-step command. It can also be defined as a score of ≤ 8 on the Glasgow Coma Scale (GCS) lasting ≥ 6 hours. For a patient to maintain consciousness, the components of ''wakefulness'' and ''awareness'' must be maintained. Wakefulness describes the quantitative degree of consciousness, whereas awareness relates to the qualitative aspects of the functions mediated by the cortex, including cognitive abilities such as attention, sensory perception, explicit memory, language, the execution of tasks, temporal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Seizure
An epileptic seizure, informally known as a seizure, is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain. Outward effects vary from uncontrolled shaking movements involving much of the body with loss of consciousness ( tonic-clonic seizure), to shaking movements involving only part of the body with variable levels of consciousness (focal seizure), to a subtle momentary loss of awareness ( absence seizure). Most of the time these episodes last less than two minutes and it takes some time to return to normal. Loss of bladder control may occur. Seizures may be provoked and unprovoked. Provoked seizures are due to a temporary event such as low blood sugar, alcohol withdrawal, abusing alcohol together with prescription medication, low blood sodium, fever, brain infection, or concussion. Unprovoked seizures occur without a known or fixable cause such that ongoing seizures are likely. Unprovoked seizures may be exacerbated by stress or sl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acute Kidney Failure
Acute kidney injury (AKI), previously called acute renal failure (ARF), is a sudden decrease in kidney function that develops within 7 days, as shown by an increase in serum creatinine or a decrease in urine output, or both. Causes of AKI are classified as either prerenal (due to decreased blood flow to the kidney), intrinsic renal (due to damage to the kidney itself), or postrenal (due to blockage of urine flow). Prerenal causes of AKI include sepsis, dehydration, excessive blood loss, cardiogenic shock, heart failure, cirrhosis, and certain medications like ACE inhibitors or NSAIDs. Intrinsic renal causes of AKI include glomerulonephritis, lupus nephritis, acute tubular necrosis, certain antibiotics, and chemotherapeutic agents. Postrenal causes of AKI include kidney stones, bladder cancer, neurogenic bladder, enlargement of the prostate, narrowing of the urethra, and certain medications like anticholinergics. The diagnosis of AKI is made based on a person's signs and symp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amantadine
Amantadine, sold under the brand name Gocovri among others, is a medication used to treat dyskinesia associated with parkinsonism and influenza caused by type A influenzavirus, though its use for the latter is no longer recommended due to widespread drug resistance. It acts as a nicotinic antagonist, dopamine agonist, and noncompetitive NMDA antagonist. The antiviral mechanism of action is antagonism of the influenzavirus A M2 proton channel, which prevents endosomal escape (i.e. the release of viral genetic material into the host cytoplasm). Amantadine was first used for the treatment of influenza A. After antiviral properties were initially reported in 1963, amantadine received approval for prophylaxis against the influenza virus A in 1976. However, amantadine-resistant influenza viruses were first reported during the 1980 influenza A epidemic and resistance frequency continued to rise into the early 2000s. Currently, amantadine is no longer recommended for the treatment of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
_jm39998.jpg "Click for more on -> José González (singer)")
.jpg "Click for more on -> Huntington's Disease")
