Walter Jennings Jones
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Walter Jennings Jones
Walter Jennings Jones (April 28, 1865 – February 28, 1935) was an American biochemist and a professor at Johns Hopkins University who was among the early investigators of the composition of the nucleic acids including the presence of nucleotides, sugar and phosphate. He also noted the presence of thermostable enzymes that could break the nucleic acids by breaking the inter-nucleotide bonds. He published his results in the 1920 book ''Nucleic Acids: Their Chemical Properties and Physiological Conduct''. Early life Jones was born in Baltimore to Zeanette Jane (née Bohen) and Levin Jones, both devout Methodists. His father was a ship chandler of his business at the Light Street Wharf in Baltimore. His father died when he was thirteen. Jones's middle name was after a physician friend of the family and he rarely used it. He was educated at local schools, and joined the City College, Baltimore in 1879 and graduated in the spring of 1884. He joined Johns Hopkins University in 1884 ...
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Baltimore
Baltimore ( , locally: or ) is the most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic, and the 30th most populous city in the United States with a population of 585,708 in 2020. Baltimore was designated an independent city by the Constitution of Maryland in 1851, and today is the most populous independent city in the United States. As of 2021, the population of the Baltimore metropolitan area was estimated to be 2,838,327, making it the 20th largest metropolitan area in the country. Baltimore is located about north northeast of Washington, D.C., making it a principal city in the Washington–Baltimore combined statistical area (CSA), the third-largest CSA in the nation, with a 2021 estimated population of 9,946,526. Prior to European colonization, the Baltimore region was used as hunting grounds by the Susquehannock Native Americans, who were primarily settled further northwest than where the city was later built. Colonist ...
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Joseph Raphael De Lamar
Joseph Raphael De Lamar (September 2, 1843 – December 1, 1918) was a prominent mine owner and operator in the western United States and Canada, as well as a financier and speculator, from the late 1870s until his death in 1918. Early life De Lamar was born in Amsterdam to Maximiliaan de la Mar (1814–1847) and Johanna Teune (1816–1867). His father, a banker in Amsterdam, died when Joseph had just turned four years old. In search of adventure, De Lamar stowed away aboard a Dutch vessel heading to the West Indies. When he was discovered, he was put to work without pay as assistant to the cook. De Lamar worked as a seaman until he was twenty, when he became master of a ship, and three years later received a captain's command. He visited many of the world's ports and acquired an education through his observations in foreign countries. He was attracted to underwater work, including salvage which was profitable owing to the American Civil War, so he abandoned the merchant ser ...
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Wittenberg University Faculty
Wittenberg ( , ; Low Saxon: ''Wittenbarg''; meaning ''White Mountain''; officially Lutherstadt Wittenberg (''Luther City Wittenberg'')), is the fourth largest town in Saxony-Anhalt, Germany. Wittenberg is situated on the River Elbe, north of Leipzig and south-west of Berlin, and has a population of 46,008 (2018). Wittenberg is famous for its close connection with Martin Luther and the Protestant Reformation, for which it received the honourific '' Lutherstadt''. Several of Wittenberg's buildings are associated with the events, including a preserved part of the Augustinian monastery in which Luther lived, first as a monk and later as owner with his wife Katharina von Bora and family, considered to be the world's premier museum dedicated to Luther. Wittenberg was also the seat of the Elector of Saxony, a dignity held by the dukes of Saxe-Wittenberg, making it one of the most powerful cities in the Holy Roman Empire. Today, Wittenberg is an industrial centre and popular touri ...
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Johns Hopkins University Alumni
Johns may refer to: Places * Johns, Mississippi, an unincorporated community * Johns, Oklahoma, United States, a community * Johns Creek (Chattahoochee River), Georgia, United States * Johns Island (other), islands in Canada and the United States * Johns Mountain, a summit in Georgia * Johns River (other) * Johns River (Vermont), a tributary of Lake Memphremagog * Johns Township, Appanoose County, Iowa, United States Other uses * Johns (surname) * Johns Hopkins (1795–1873), American entrepreneur, investor and philanthropist * ''johns'' (film), a 1996 film starring David Arquette and Lukas Haas See also * John (other) * Justice Johns (other) * {{disambig, geo ...
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American Biochemists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ...
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1935 Deaths
Events January * January 7 – Italian premier Benito Mussolini and French Foreign Minister Pierre Laval conclude an agreement, in which each power agrees not to oppose the other's colonial claims. * January 12 – Amelia Earhart becomes the first person to successfully complete a solo flight from Hawaii to California, a distance of 2,408 miles. * January 13 – A plebiscite in the Territory of the Saar Basin shows that 90.3% of those voting wish to join Germany. * January 24 – The first canned beer is sold in Richmond, Virginia, United States, by Gottfried Krueger Brewing Company. February * February 6 – Parker Brothers begins selling the board game Monopoly in the United States. * February 13 – Richard Hauptmann is convicted and sentenced to death for the kidnapping and murder of Charles Lindbergh Jr. in the United States. * February 15 – The discovery and clinical development of Prontosil, the first broadly effective antibiotic, is published in a se ...
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1865 Births
Events January–March * January 4 – The New York Stock Exchange opens its first permanent headquarters at 10-12 Broad near Wall Street, in New York City. * January 13 – American Civil War : Second Battle of Fort Fisher: United States forces launch a major amphibious assault against the last seaport held by the Confederates, Fort Fisher, North Carolina. * January 15 – American Civil War: United States forces capture Fort Fisher. * January 31 ** The Thirteenth Amendment to the United States Constitution (conditional prohibition of slavery and involuntary servitude) passes narrowly, in the House of Representatives. ** American Civil War: Confederate General Robert E. Lee becomes general-in-chief. * February ** American Civil War: Columbia, South Carolina burns, as Confederate forces flee from advancing Union forces. * February 3 – American Civil War : Hampton Roads Conference: Union and Confederate leaders discuss peace terms. * February 8 ...
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MedStar Union Memorial Hospital
MedStar Union Memorial Hospital is a non-profit, acute care teaching hospital located in the North Central section of Baltimore, Maryland. The hospital is a member of MedStar Health, a community-based network of Baltimore/Washington, D.C. area hospitals and other health care services. In 2014, the magazine '' U.S. News & World Report'' ranked the hospital 10th in Maryland, and 9th in the Baltimore metropolitan area. For cardiology, cardiac surgery, and orthopedic surgery, it is ranked among the top 50 hospitals in the U.S.. Jazz leader Chick Webb worked in the hospital as a youngster, and Mickey Mantle received treatment at the hospital. In 1939, the gangster Al Capone spent time at the hospital to cure his paresis caused by syphilis, after his release from Alcatraz, after which he donated two cherry tree A cherry is the fruit of many plants of the genus ''Prunus'', and is a fleshy drupe (stone fruit). Commercial cherries are obtained from cultivars of several species, such ...
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Ocean Grove, New Jersey
Ocean Grove is a unincorporated community and census-designated place (CDP) located within Neptune Township, Monmouth County, New Jersey, United States.New Jersey: 2010 – Population and Housing Unit Counts – 2010 Census of Population and Housing (CPH-2-32)
, August 2012. Accessed December 16, 2012.
It had a population of 3,342 at the .
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Pancreatic Ribonuclease Family
Pancreatic ribonuclease family (, ''RNase'', ''RNase I'', ''RNase A'', ''pancreatic RNase'', ''ribonuclease I'', ''endoribonuclease I'', ''ribonucleic phosphatase'', ''alkaline ribonuclease'', ''ribonuclease'', ''gene S glycoproteins'', ''Ceratitis capitata alkaline ribonuclease'', ''SLSG glycoproteins'', ''gene S locus-specific glycoproteins'', ''S-genotype-assocd. glycoproteins'', ''ribonucleate 3'-pyrimidino-oligonucleotidohydrolase'') is a superfamily of pyrimidine-specific endonucleases found in high quantity in the pancreas of certain mammals and of some reptiles. Specifically, the enzymes are involved in endonucleolytic cleavage of 3'-phosphomono nucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates. Ribonuclease can unwind the RNA helix by complexing with single-stranded RNA; the complex arises by an extended multi-site cation-anion interaction between lysine and arginine residues of the enzyme and phosphate groups of t ...
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Phoebus Levene
Phoebus Aaron Theodore Levene (25 February 1869 – 6 September 1940) was a Russian born American biochemist who studied the structure and function of nucleic acids. He characterized the different forms of nucleic acid, DNA from RNA, and found that DNA contained adenine, guanine, thymine, cytosine, deoxyribose, and a phosphate group. He was born into a Litvak (Lithuanian Jewish) family as ''Fishel Rostropovich Levin'' in the town of Žagarė in Lithuania, then part of the Russian Empire, but grew up in St. Petersburg. There he studied medicine at the Imperial Military Medical Academy (M.D., 1891) and developed an interest in biochemistry. In 1893, because of anti-Semitic pogroms, he and his family emigrated to the United States and he practiced medicine in New York City. Levene enrolled at Columbia University and in his spare time conducted biochemical research, publishing papers on the chemical structure of sugars. In 1896 he was appointed as an Associate in the Pathol ...
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Tetranucleotide Hypothesis
The tetranucleotide hypothesis of Phoebus Levene proposed that DNA was composed of repeating sequences of four nucleotides. It was very influential for three decades, and was developed by Levene at least into the 1930s, and the diagram at the right illustrates the view of Levene and Tipson. In 1940, at the time of Levene's death, Bass wrote in his obituary As a result of Levene’s work we have an exact concept of the structures of these huge molecules, probably the most complex biological materials whose architectural picture has been reconstructed. In that form there is an implication that the four bases are present in equal amounts in DNA, and small variations in the experimental values were assumed to be the result of experimental error. However, Erwin Chargaff showed that the four frequencies were not equal, with variations consistent between different studies. Specifically, according to his rules Rule or ruling may refer to: Education * Royal University of Law and Ec ...
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