Valerie Speirs
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Valerie Speirs
Valerie Speirs is a Professor of Molecular Oncology at the University of Aberdeen. Her research aims to identify biomarkers of breast cancer to inform diagnosis and treatment. Education Speirs studied zoology at the University of Aberdeen. She completed her graduate studies at the University of Glasgow. She worked with Ian Freshney on cell culture and became interested in how cell culture systems can be used to model disease. Career and research Speirs research investigates Cancer biology, Breast cancer and Molecular pathology. Speirs joined The Hospital for Sick Children. Speirs worked at the University of Hull on the expression of oestrogen receptor mRNA. She looked at the role of the CGA gene in endocrine response. Speirs was a member of the Breast Cancer Campaign Scientific Advisory Board in 2008. She joined the Irish Health Research Board in 2009. She served as principal investigator of the Leeds Breast Cancer Campaign Tissue Bank. She oversaw the launch o ...
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University Of Aberdeen
The University of Aberdeen ( sco, University o' 'Aiberdeen; abbreviated as ''Aberd.'' in List of post-nominal letters (United Kingdom), post-nominals; gd, Oilthigh Obar Dheathain) is a public university, public research university in Aberdeen, Scotland. It is an Ancient universities of Scotland, ancient university founded in 1495 when William Elphinstone, Bishop of Aberdeen and Lord Chancellor of Scotland, Chancellor of Scotland, petitioned Pope Alexander VI on behalf of James IV of Scotland, James IV, King of Scots to establish King's College, Aberdeen, King's College, making it Scotland's 3rd oldest university and the 5th oldest in the English-speaking world and the United Kingdom. Aberdeen is consistently ranked among the top 160 universities in the world and is ranked within the top 20 universities in the United Kingdom according to ''The Times'' and ''The Sunday Times'', and 13th in the UK according to ''The Guardian''. The university comprises three colleges—King's College ...
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St James's University Hospital
St James's University Hospital ''Confirming name as "St James's"'' is in Leeds, West Yorkshire, England and is popularly known as Jimmy's. It is one of the United Kingdom's most famous hospitals due to its coverage on television. It is managed by the Leeds Teaching Hospitals NHS Trust. History The hospital has its origins in the Leeds Moral and Industrial Training School built in 1848 (which now forms part of the Lincoln Wing). Subsequent early developments included the Leeds Union Workhouse (which now houses the Thackray Medical Museum) built in 1858. The chapel, which is a Grade II listed building, was completed in 1861 by the firm of Perkin & Beckhouse, of Leeds, and the Leeds Union Infirmary (the site of the present Gledhow Wing) was built in 1874.P. M Pennock ''Publications of the Thoresby Society'', Vol LIX part 2, no 130, pp. 124–76 "The Evolution of St James's 1848–97" By the end of the 19th century, the facilities were largely used for medical care of the poor, ...
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Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calendar year (the ...
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Royal College Of Pathologists
The Royal College of Pathologists (RCPath) is a professional membership organisation. Its main function is the overseeing of postgraduate training, and its Fellowship Examination (FRCPath) is recognised as the standard assessment of fitness to practise in this branch of medicine. Constitution The Royal College of Pathologists is a professional membership organisation, to maintain the standards and reputation of British pathology, through training, assessments, examinations and professional development. It is a registered charity and is not a trades union. Its 11,000 members work in hospital laboratories, universities and industry worldwide. History The College of Pathologists was founded in 1962, to optimise postgraduate training in the relatively young science of pathology, with its high importance in the diagnostic process, and the increasing range of specialist studies within it. The College received its Royal Charter in 1970 and its Patron is Her Majesty Queen Elizabeth II. ...
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Fellow
A fellow is a concept whose exact meaning depends on context. In learned or professional societies, it refers to a privileged member who is specially elected in recognition of their work and achievements. Within the context of higher educational institutions, a fellow can be a member of a highly ranked group of teachers at a particular college or university or a member of the governing body in some universities (such as the Fellows of Harvard College); it can also be a specially selected postgraduate student who has been appointed to a post (called a fellowship) granting a stipend, research facilities and other privileges for a fixed period (usually one year or more) in order to undertake some advanced study or research, often in return for teaching services. In the context of research and development-intensive large companies or corporations, the title "fellow" is sometimes given to a small number of senior scientists and engineers. In the context of medical education in No ...
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BMC Cancer
BMC may refer to: Business and organizations * Beard Miller Company, a US public accounting firm * BioMed Central, a UK-based scientific publisher * BMC Software, an American business service management software vendor * BMC Switzerland, a Swiss bicycle products manufacturer and sponsor of professional cycling * BMC (Turkey), a Turkish vehicle manufacturer * Boston Micromachines Corporation, a manufacturer of microelectromechanical deformable mirrors * Brega Marketing Company, a Libyan company for marketing petroleum and related products * British Motor Corporation, a UK vehicle company ** British Motor Corporation (Australia), the Australian arm of the British Motor Corporation * British Mountaineering Council * Bulk mail center * Burma Muslim Congress, a former political party in Myanmar * Business Model Canvas a canvas diagram invented by Alexander Osterwalder * Buy Me a Coffee, an American crowdfunding company Education * Bangalore Medical College * Belfast Metropolitan Colle ...
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H-index
The ''h''-index is an author-level metric that measures both the productivity and citation impact of the publications, initially used for an individual scientist or scholar. The ''h''-index correlates with obvious success indicators such as winning the Nobel Prize, being accepted for research fellowships and holding positions at top universities. The index is based on the set of the scientist's most cited papers and the number of citations that they have received in other publications. The index has more recently been applied to the productivity and impact of a scholarly journal as well as a group of scientists, such as a department or university or country. The index was suggested in 2005 by Jorge E. Hirsch, a physicist at UC San Diego, as a tool for determining theoretical physicists' relative quality and is sometimes called the Hirsch index or Hirsch number. Definition and purpose The ''h''-index is defined as the maximum value of ''h'' such that the given author/journa ...
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In Vitro
''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, and whole plants. Definition ''In vitro'' ( la, in glass; often not italicized in English usage) studies are conducted using components of an organism that have been isolated fro ...
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Fibroblast
A fibroblast is a type of cell (biology), biological cell that synthesizes the extracellular matrix and collagen, produces the structural framework (Stroma (tissue), stroma) for animal Tissue (biology), tissues, and plays a critical role in wound healing. Fibroblasts are the most common cells of connective tissue in animals. Structure Fibroblasts have a branched cytoplasm surrounding an elliptical, speckled cell nucleus, nucleus having two or more nucleoli. Active fibroblasts can be recognized by their abundant Endoplasmic reticulum#Rough endoplasmic reticulum, rough endoplasmic reticulum. Inactive fibroblasts (called fibrocytes) are smaller, spindle-shaped, and have a reduced amount of rough endoplasmic reticulum. Although disjointed and scattered when they have to cover a large space, fibroblasts, when crowded, often locally align in parallel clusters. Unlike the epithelial cells lining the body structures, fibroblasts do not form flat monolayers and are not restricted by a ...
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MiRNA
MicroRNA (miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides. Found in plants, animals and some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression. miRNAs base-pair to complementary sequences in mRNA molecules, then gene silence said mRNA molecules by one or more of the following processes: (1) cleavage of mRNA strand into two pieces, (2) destabilization of mRNA by shortening its poly(A) tail, or (3) translation of mRNA into proteins. This last method of gene silencing is the least efficient of the three, and requires the aid of ribosomes. miRNAs resemble the small interfering RNAs (siRNAs) of the RNA interference (RNAi) pathway, except miRNAs derive from regions of RNA transcripts that fold back on themselves to form short hairpins, whereas siRNAs derive from longer regions of double-stranded RNA. The human genome may encode over 1900 miRNAs, although more recent analysis suggests that ...
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University Of Bradford
The University of Bradford is a Public university, public research university located in the city of Bradford, West Yorkshire, England. A plate glass university, it received its royal charter in 1966, making it the 40th university to be created in Britain, but can trace its origins back to the establishment of the industrial West Yorkshire town's Mechanics Institute in 1832. The student population includes undergraduate and postgraduate students. Mature students make up around a third of the undergraduate community. A total of 22% of students are international students, foreign and come from over 110 countries. There were 14,406 applications to the university through UCAS in 2010, of which 3,421 were accepted. It was the first British university to establish a Department of Peace Studies, University of Bradford, Department of Peace Studies in 1973, which is currently the world's largest university centre for the study of peace and conflict. History The university's or ...
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 ''Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in exp ...
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