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Visual Hallucinations In Psychosis
Visual hallucinations in psychosis are hallucinations accompanied by delusions. Presentation Visual hallucinations in psychoses are reported to have physical properties similar to real perceptions. They are often life-sized, detailed, and solid, and are projected into the external world. They typically appear anchored in external space, just beyond the reach of individuals, or further away. They can have three-dimensional shapes, with depth and shadows, and distinct edges. They can be colorful or in black and white and can be static or have movement. Simple vs. complex Visual hallucinations may be simple, or non-formed visual hallucinations, or complex, or formed visual hallucinations. Simple visual hallucinations without structure are known as phosphenes and those with geometric structure are known as photopsias. These hallucinations are caused by irritation to the primary visual cortex ( Brodmann's area 17). Sometimes, hallucinations are 'Lilliputian', i.e., patients expe ...
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Hallucination
A hallucination is a perception in the absence of an external stimulus that has the qualities of a real perception. Hallucinations are vivid, substantial, and are perceived to be located in external objective space. Hallucination is a combination of 2 conscious states of brain wakefulness and REM sleep. They are distinguishable from several related phenomena, such as dreaming ( REM sleep), which does not involve wakefulness; pseudohallucination, which does not mimic real perception, and is accurately perceived as unreal; illusion, which involves distorted or misinterpreted real perception; and mental imagery, which does not mimic real perception, and is under voluntary control. Hallucinations also differ from " delusional perceptions", in which a correctly sensed and interpreted stimulus (i.e., a real perception) is given some additional significance. Many hallucinations happen also during sleep paralyses. Hallucinations can occur in any sensory modality—visual, audito ...
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Phosphenes
A phosphene is the phenomenon of seeing light without light entering the eye. The word ''phosphene'' comes from the Greek words ''phos'' (light) and ''phainein'' (to show). Phosphenes that are induced by movement or sound may be associated with optic neuritis. Phosphenes can be induced by mechanical, electrical, or magnetic stimulation of the retina or visual cortex, or by random firing of cells in the visual system. Phosphenes have also been reported by meditators (called ''nimitta''), people who endure long periods without visual stimulation (the prisoner's cinema), or those who ingest psychedelic drugs. Causes Mechanical stimulation The most common phosphenes are pressure phosphenes, caused by rubbing or applying pressure on or near the closed eyes. They have been known since antiquity, and described by the Greeks. The pressure mechanically stimulates the cells of the retina. Experiences include a darkening of the visual field that moves against the rubbing, a diffuse ...
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Photopsias
Photopsia is the presence of perceived flashes of light in the field of vision. It is most commonly associated with: * posterior vitreous detachment * migraine aura (ocular migraine / retinal migraine) * migraine aura without headache * scintillating scotoma * retinal break or detachment * occipital lobe infarction (similar to occipital stroke) * sensory deprivation (ophthalmopathic hallucinations) * age-related macular degeneration * vertebrobasilar insufficiency * optic neuritis * visual snow syndrome Vitreous shrinkage or liquefaction, which are the most common causes of photopsia, cause a pull in vitreoretinal attachments, irritating the retina and causing it to discharge electrical impulses. These impulses are interpreted by the brain as flashes. This condition has also been identified as a common initial symptom of punctate inner choroiditis ( PIC), a rare retinal autoimmune disease believed to be caused by the immune system mistakenly attacking and destroying the r ...
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Primary Visual Cortex
The visual cortex of the brain is the area of the cerebral cortex that processes visual information. It is located in the occipital lobe. Sensory input originating from the eyes travels through the lateral geniculate nucleus in the thalamus and then reaches the visual cortex. The area of the visual cortex that receives the sensory input from the lateral geniculate nucleus is the primary visual cortex, also known as visual area 1 ( V1), Brodmann area 17, or the striate cortex. The extrastriate areas consist of visual areas 2, 3, 4, and 5 (also known as V2, V3, V4, and V5, or Brodmann area 18 and all Brodmann area 19). Both hemispheres of the brain include a visual cortex; the visual cortex in the left hemisphere receives signals from the right visual field, and the visual cortex in the right hemisphere receives signals from the left visual field. Introduction The primary visual cortex (V1) is located in and around the calcarine fissure in the occipital lobe. Each hemispher ...
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Brodmann Area 17
The visual cortex of the brain is the area of the cerebral cortex that processes visual information. It is located in the occipital lobe. Sensory input originating from the eyes travels through the lateral geniculate nucleus in the thalamus and then reaches the visual cortex. The area of the visual cortex that receives the sensory input from the lateral geniculate nucleus is the primary visual cortex, also known as visual area 1 ( V1), Brodmann area 17, or the striate cortex. The extrastriate areas consist of visual areas 2, 3, 4, and 5 (also known as V2, V3, V4, and V5, or Brodmann area 18 and all Brodmann area 19). Both hemispheres of the brain include a visual cortex; the visual cortex in the left hemisphere receives signals from the right visual field, and the visual cortex in the right hemisphere receives signals from the left visual field. Introduction The primary visual cortex (V1) is located in and around the calcarine fissure in the occipital lobe. Each hemisphere's V1 ...
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Parkinson's
Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms become more common. The most obvious early symptoms are tremor, rigidity, slowness of movement, and difficulty with walking. Cognitive and behavioral problems may also occur with depression, anxiety, and apathy occurring in many people with PD. Parkinson's disease dementia becomes common in the advanced stages of the disease. Those with Parkinson's can also have problems with their sleep and sensory systems. The motor symptoms of the disease result from the death of cells in the substantia nigra, a region of the midbrain, leading to a dopamine deficit. The cause of this cell death is poorly understood, but involves the build-up of misfolded proteins into Lewy bodies in the neurons. Collectively, the main motor symptoms are also known as pa ...
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Serotonin
Serotonin () or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction. Approximately 90% of the serotonin that the body produces is in the intestinal tract. Biochemically, the indoleamine molecule derives from the amino acid tryptophan, via the (rate-limiting) Tryptophan hydroxylase, hydroxylation of the 5 position on the ring (forming the intermediate 5-Hydroxytryptophan, 5-hydroxytryptophan), and then Aromatic L-amino acid decarboxylase, decarboxylation to produce serotonin. Serotonin is primarily found in the enteric nervous system located in the human gastrointestinal tract, gastrointestinal tract (GI tract). However, it is also produced in the central nervous system (CNS), specifically in the raphe nuclei located in the brainstem, Merkel cells located in the skin, Neuroendocrine cell#Pulmo ...
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Acetylcholine
Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals (including humans) as a neurotransmitter. Its name is derived from its chemical structure: it is an ester of acetic acid and choline. Parts in the body that use or are affected by acetylcholine are referred to as cholinergic. Substances that increase or decrease the overall activity of the cholinergic system are called cholinergics and anticholinergics, respectively. Acetylcholine is the neurotransmitter used at the neuromuscular junction—in other words, it is the chemical that motor neurons of the nervous system release in order to activate muscles. This property means that drugs that affect cholinergic systems can have very dangerous effects ranging from paralysis to convulsions. Acetylcholine is also a neurotransmitter in the autonomic nervous system, both as an internal transmitter for the sympathetic nervous system and as the final product released by the para ...
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Visual Cortex
The visual cortex of the brain is the area of the cerebral cortex that processes visual information. It is located in the occipital lobe. Sensory input originating from the eyes travels through the lateral geniculate nucleus in the thalamus and then reaches the visual cortex. The area of the visual cortex that receives the sensory input from the lateral geniculate nucleus is the primary visual cortex, also known as visual area 1 ( V1), Brodmann area 17, or the striate cortex. The extrastriate areas consist of visual areas 2, 3, 4, and 5 (also known as V2, V3, V4, and V5, or Brodmann area 18 and all Brodmann area 19). Both hemispheres of the brain include a visual cortex; the visual cortex in the left hemisphere receives signals from the right visual field, and the visual cortex in the right hemisphere receives signals from the left visual field. Introduction The primary visual cortex (V1) is located in and around the calcarine fissure in the occipital lobe. Each hemisphe ...
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Brodmann Area 18
Human Brodmann area 18, or BA18, is part of the occipital cortex in the human brain. It accounts for the bulk of the volume of the occipital lobe. It is known as a "Visual Association Area" or V2 and is a first stage in processing or feature extraction of retinotopic images from V1. This area is also known as parastriate area 18. It is a subdivision of the cytoarchitecturally defined occipital region of cerebral cortex. In the human it is located in parts of the cuneus, the lingual gyrus and the lateral occipital gyrus (H) of the occipital lobe. It is bounded on one side by the Brodmann area 17, from which it is distinguished by absence of a band of Gennari, and on the other by the peristriate area 19 (Brodmann-1909). Guenon Brodmann area 18 is a subdivision of the cerebral cortex of the guenon defined on the basis of cytoarchitecture. It is topographically and cytoarchitecturally homologous to parastriate area 18 of the human (Brodmann-1909). Distinctive features (Brodm ...
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Brodmann Area 19
Brodmann area 19, or BA 19, is part of the occipital lobe cortex in the human brain. Along with area 18, it comprises the extrastriate (or peristriate) cortex. In humans with normal sight, extrastriate cortex is a visual association area, with feature-extracting, shape recognition, attentional, and multimodal integrating functions. This area is also known as peristriate area 19, and it refers to a subdivision of the cytoarchitecturally defined occipital region of cerebral cortex. In the human it is located in parts of the lingual gyrus, the cuneus, the lateral occipital gyrus (H) and the superior occipital gyrus (H) of the occipital lobe where it is bounded approximately by the parieto-occipital sulcus. It is bounded on one side by the parastriate area 18, which it surrounds. It is bounded rostrally by the angular area 39 (H) and the occipitotemporal area 37 (H) (Brodmann-1909). In animals Brodmann area 19-1909 is a subdivision of the cerebral cortex of the guenon defined on th ...
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Deafferentation
Peripheral neuropathy, often shortened to neuropathy, is a general term describing disease affecting the peripheral nerves, meaning nerves beyond the brain and spinal cord. Damage to peripheral nerves may impair sensation, movement, gland, or organ function depending on which nerves are affected; in other words, neuropathy affecting motor, sensory, or autonomic nerves result in different symptoms. More than one type of nerve may be affected simultaneously. Peripheral neuropathy may be acute (with sudden onset, rapid progress) or chronic (symptoms begin subtly and progress slowly), and may be reversible or permanent. Common causes include systemic diseases (such as diabetes or leprosy), hyperglycemia-induced glycation, vitamin deficiency, medication (e.g., chemotherapy, or commonly prescribed antibiotics including metronidazole and the fluoroquinolone class of antibiotics (such as ciprofloxacin, levofloxacin, moxifloxacin)), traumatic injury, ischemia, radiation therapy, excessiv ...
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