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Vijendra K. Singh
Vijendra Kumar Singh is a neuroimmunologist who formerly held a post at Utah State University, prior to which he was a professor at the University of Michigan. While affiliated with both institutions, he conducted some controversial autism-related research focusing on the potential role of immune system disorders in the etiology of autism. For example, he has testified before a US congressional committee that, in his view, "three quarters of autistic children suffer from an autoimmune disease." Career Singh originally worked at a children's hospital in Vancouver, and is the author of over 100 scientific publications. The original focus of his research was neurochemistry, but his interest in the role of the immune system in neurodevelopmental disorders was sparked after reading an article on the mind-body relationship, which proposed a biological mechanism to explain the signaling taking place both in the brain and in the immune system. In 2004, Singh gave a talk before the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Utah State University
Utah State University (USU or Utah State) is a public land-grant research university in Logan, Utah. It is accredited by the Northwest Commission on Colleges and Universities. With nearly 20,000 students living on or near campus, USU is Utah's largest public residential campus. As of Fall 2022, there were 27,943 students enrolled, including 24,835 undergraduate students and 3,108 graduate students. The university has the highest percentage of out-of-state students of any public university in Utah, totaling 23% of the student body. Founded in 1888 as Utah's land-grant college, USU focused on science, engineering, agriculture, domestic arts, military science, and mechanic arts. The university offers programs in liberal arts, engineering, business, economics, natural resource sciences, and nationally ranked elementary & secondary education programs. It offers master's and doctoral programs in humanities, social sciences, and STEM areas (science, technology, engineering, and mathe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reproducibility
Reproducibility, also known as replicability and repeatability, is a major principle underpinning the scientific method. For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated. There are different kinds of replication but typically replication studies involve different researchers using the same methodology. Only after one or several such successful replications should a result be recognized as scientific knowledge. With a narrower scope, ''reproducibility'' has been introduced in computational sciences: Any results should be documented by making all data and code available in such a way that the computations can be executed again with identical results. In recent decades, there has been a rising concern that many published scientific results fail the test of reproducibility, evoking a r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Steroid
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and as signaling molecules. Hundreds of steroids are found in plants, animals and fungi. All steroids are manufactured in cells from the sterols lanosterol (opisthokonts) or cycloartenol (plants). Lanosterol and cycloartenol are derived from the cyclization of the triterpene squalene. The steroid core structure is typically composed of seventeen carbon atoms, bonded in four " fused" rings: three six-member cyclohexane rings (rings A, B and C in the first illustration) and one five-member cyclopentane ring (the D ring). Steroids vary by the functional groups attached to this four-ring core and by the oxidation state of the rings. Sterols are forms of steroids with a hydroxy group at position three and a skeleton derived from cholestane. ''A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glyconutrient
Mannatech is a publicly traded, multinational multi-level marketing firm that sells dietary supplements and personal care products. It was founded in November 1993 by Samuel Caster, and is headquartered in Flower Mound, Texas. The company's stock is traded on the NASDAQ exchange under the symbol MTEX. As of 2017, Mannatech employed 252 people and sold its products through some 220,000 independent sales associates. In 2007, Mannatech and its salespeople made false claims of anti-disease benefits about its lead product called "Ambrotose" which contains sugars derived from plants. The company was profitable soon after its founding until about 2008, when it started losing money due to exposure of its business practices through a class action lawsuit based on the false health claims, a critical ''20/20'' news special, and a civil suit filed by the Attorney General of Texas. History Mannatech was founded by Samuel Caster in 1993, as Congress prepared to pass the Dietary Supplement ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transfer Factor
Transfer factors are essentially small immune messenger molecules that are produced by all higher organisms. Transfer factors were originally described as immune molecules that are derived from blood or spleen cells that cause antigen-specific cell-mediated immunity, primarily delayed hypersensitivity and the production of lymphokines, as well as binding to the antigens themselves. They have a molecular weight of approximately 5000 daltons and are composed entirely of amino acids. Transfer factors were discovered by Henry Sherwood Lawrence in 1954. A second use of the term transfer factor applies to a likely different entity derived from cow colostrum or chicken egg yolk which is marketed as an oral dietary supplement under the same name citing claims of benefit to the immune system. History In 1942, Merrill Chase discovered that cells taken from the peritoneum of Guinea pigs that had been immunized against an antigen could transfer immunity when injected into Guinea pigs t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nutraceuticals
A nutraceutical or bioceutical is a pharmaceutical alternative which claims physiological benefits. In the US, "nutraceuticals" are largely unregulated, as they exist in the same category as dietary supplements and food additives by the FDA, under the authority of the Federal Food, Drug, and Cosmetic Act. Regulation Nutraceuticals are treated differently in different jurisdictions. Canada Under Canadian law, a nutraceutical can either be marketed as a food or as a drug; the terms "nutraceutical" and "functional food" have no legal distinction, referring to "a product isolated or purified from foods that is generally sold in medicinal forms not usually associated with food ndis demonstrated to have a physiological benefit or provide protection against chronic disease." United States The terms "nutraceutical" and 'bioceutical' are not defined by US law. Depending on its ingredients and the claims with which it is marketed, a product is regulated as a drug, dietary supplement ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Autoantibodies
An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins. Many autoimmune diseases (notably lupus erythematosus) are associated with such antibodies. Production Antibodies are produced by B cells in two ways: (i) randomly, and (ii) in response to a foreign protein or substance within the body. Initially, one B cell produces one specific kind of antibody. In either case, the B cell is allowed to proliferate or is killed off through a process called clonal deletion. Normally, the immune system is able to recognize and ignore the body's own healthy proteins, cells, and tissues, and to not overreact to non-threatening substances in the environment, such as foods. Sometimes, the immune system ceases to recognize one or more of the body's normal constituents as "self," leading to production of pathological autoantibodies. Autoantibodies may also play a nonpathological role; for instance they m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Autoimmunity
In immunology, autoimmunity is the system of immune responses of an organism against its own healthy cells, tissues and other normal body constituents. Any disease resulting from this type of immune response is termed an "autoimmune disease". Prominent examples include celiac disease, post-infectious IBS, diabetes mellitus type 1, Henoch–Schönlein purpura (HSP) sarcoidosis, systemic lupus erythematosus (SLE), Sjögren syndrome, eosinophilic granulomatosis with polyangiitis, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, Addison's disease, rheumatoid arthritis (RA), ankylosing spondylitis, polymyositis (PM), dermatomyositis (DM), Alopecia Areata and multiple sclerosis (MS). Autoimmune diseases are very often treated with steroids. Autoimmunity means presence of antibodies or T cells that react with self-protein and is present in all individuals, even in normal health state. It causes autoimmune diseases if self-reactivity can lead to tiss ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dan Burton
Danny Lee Burton (born June 21, 1938) is an American politician. Burton is the former U.S. Representative for , and previously the , serving from 1983 until 2013. He is a member of the Republican Party and was part of the Tea Party Caucus. Early life, education, and early career Burton was born in Indianapolis, the son of Bonnie L. (née Hardesty) and Charles W. Burton. His father, a former policeman, was abusive to his mother, and never held a job for very long. The family moved constantly, living in trailer parks, cabins, and motels. In June 1950, some years after the couple divorced, his mother went to the police and got a restraining order against his father. He responded by kidnapping Burton's mother. Burton and his younger brother and sister were briefly sent to the Marion County Children's Guardian Home. After his mother escaped, Burton's father went to jail for two years. Burton's mother remarried, and Burton and his younger brother and sister had happier teenage years. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Committee On Government Reform
The Committee on Oversight and Reform is the main investigative committee of the United States House of Representatives. The committee's broad jurisdiction and legislative authority make it one of the most influential and powerful panels in the House. Its chairman is one of only three in the House with the authority to issue subpoenas without a committee vote or consultation with the ranking member. However, in recent history, it has become practice to refrain from unilateral subpoenas. Carolyn Maloney ( D-New York) served as acting chair of the committee following the death of Elijah Cummings ( D-Maryland) on October 17, 2019; she was elected chair a month later. Representative Jim Jordan served as ranking member from January 3, 2019, until March 12, 2020. On March 31, 2020, Jordan started his second stint as ranking member. Representative Mark Meadows served as ranking member from March 13, 2020, until March 30, 2020, when he resigned his congressional seat to become White Ho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academy Of Medical Sciences, United Kingdom
The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of the four UK National Academies, the others being the British Academy, the Royal Academy of Engineering and the Royal Society. Its mission is to advance biomedical and health research and its translation into benefits for society. The academy consists of a group of around 1200 Fellows elected from fields across the biomedical sciences. The academy seeks ultimately to advance medical science and improve health by investing in talented researchers, engaging people on health-related issues and providing expert impartial advice. its president is Dame Anne Johnson. History The academy was established in 1998 following the recommendations of a working group chaired by Michael Atiyah, former president of the Royal Society. A single national organisation was formed to support biomedical scientists and clinical academics working together to promote advances in medical science. It is one ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peter Lachmann
Sir Peter Julius Lachmann (23 December 1931 – 26 December 2020) was a British immunologist, specialising in the study of the Complement system, complement system. He was emeritus Sheila Joan Smith Professor of Immunology at the University of Cambridge, a fellow of Christ's College, Cambridge and honorary fellow of Trinity College, Cambridge and of Imperial College. He was knighted for service to medical science in 2002. Biography Born into a Jewish family in Berlin on 23 December 1931, he moved to London in 1938. He went to school at Christ's College, Finchley, Lachmann's own account of GMOs and the Pusztai affair can be found in ''Panic Nation'' (2005). Lachmann was a proponent of the defence of reason and scepticism in scientific academia and on topics that extend from vaccine scares to stem cell technology and to alternative medicine. He was also a bee keeper and this interest has led to an interest in the evolution of group behaviour in both bees and humans and the role ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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