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UTP18
U3 small nucleolar RNA-associated protein 18 homolog is a protein that in humans is encoded by the ''UTP18'' gene. See also * Fibrillarin * Small nucleolar RNA U3 * RCL1 * RRP9 * UTP11L * UTP14A * UTP15 U3 small nucleolar RNA-associated protein 15 homolog is a protein that in humans is encoded by the ''UTP15'' gene. See also * Fibrillarin * Small nucleolar RNA U3 * RCL1 * RRP9 * UTP6 * UTP11L * UTP14A U3 small nucleolar RNA-associated prote ... References Further reading * * * * * * * * {{gene-17-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fibrillarin
rRNA 2'-O-methyltransferase fibrillarin is an enzyme that in humans is encoded by the ''FBL'' gene. Function This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing pre-ribosomal (r)RNA. It is associated with the U3, U8, and U13 small nucleolar RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. Fibrillarin is a component of several ribonucleoproteins including a nucleolar small nuclear ribonucleoprotein (SnRNP) and one of the two classes of small nucleolar ribonucleoproteins (snoRNPs). SnRNAs function in RNA splicing whi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Small Nucleolar RNA U3
In molecular biology, U3 snoRNA is a non-coding RNA found predominantly in the nucleolus. U3 has C/D box motifs that technically make it a member of the box C/D class of snoRNAs; however, unlike other C/D box snoRNAs, it has not been shown to direct 2'-''O''-methylation of other RNAs. Rather, U3 is thought to guide site-specific cleavage of ribosomal RNA (rRNA) during pre-rRNA processing. The box C/D element is a subset of the six short sequence elements found in all U3 snoRNAs, namely boxes A, A', B, C, C', and D. The U3 snoRNA secondary structure is characterized by a small 5' domain (with boxes A and A'), and a larger 3' domain (with boxes B, C, C', and D), the two domains being linked by a single-stranded hinge. Boxes B and C form the B/C motif, which appears to be exclusive to U3 snoRNAs, and boxes C' and D form the C'/D motif. The latter is functionally similar to the C/D motifs found in other snoRNAs. The 5' domain and the hinge region act as a pre-rRNA-binding domain. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RCL1
RNA 3'-terminal phosphate cyclase-like protein is an enzyme that in humans is encoded by the ''RCL1'' gene. Copy number variants to the RCL1 gene are associated with a range of neuropsychiatric phenotypes, and a missense variant associated with depression. See also * Fibrillarin * Small nucleolar RNA U3 * RRP9 * UTP6 * UTP11L * UTP14A * UTP15 U3 small nucleolar RNA-associated protein 15 homolog is a protein that in humans is encoded by the ''UTP15'' gene. See also * Fibrillarin * Small nucleolar RNA U3 * RCL1 * RRP9 * UTP6 * UTP11L * UTP14A U3 small nucleolar RNA-associated prote ... References Further reading * * * * * * * * * External links * * {{gene-9-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RRP9
U3 small nucleolar RNA-interacting protein 2 is a protein that in humans is encoded by the ''RRP9'' gene. See also * Fibrillarin * Small nucleolar RNA U3 * RCL1 * RRP9 * UTP6 * UTP11L * UTP14A * UTP15 U3 small nucleolar RNA-associated protein 15 homolog is a protein that in humans is encoded by the ''UTP15'' gene. See also * Fibrillarin * Small nucleolar RNA U3 * RCL1 * RRP9 * UTP6 * UTP11L * UTP14A U3 small nucleolar RNA-associated prote ... References Further reading * * * * * * * * * * External links PDBe-KB provides an overview of all the structure information available in the PDB for Human U3 small nucleolar RNA-interacting protein 2 (RRP9) {{gene-3-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UTP11L
Probable U3 small nucleolar RNA-associated protein 11 is a protein that in humans is encoded by the ''UTP11L'' gene. See also * Fibrillarin * Small nucleolar RNA U3 * RCL1 * RRP9 * UTP6 * UTP14A * UTP15 U3 small nucleolar RNA-associated protein 15 homolog is a protein that in humans is encoded by the ''UTP15'' gene. See also * Fibrillarin * Small nucleolar RNA U3 * RCL1 * RRP9 * UTP6 * UTP11L * UTP14A U3 small nucleolar RNA-associated prote ... References Further reading * * * * * * * * * {{gene-1-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UTP14A
U3 small nucleolar RNA-associated protein 14 homolog A is a protein that in humans is encoded by the ''UTP14A'' gene. See also * Fibrillarin * Small nucleolar RNA U3 * RCL1 * RRP9 * UTP6 * UTP11L * UTP15 U3 small nucleolar RNA-associated protein 15 homolog is a protein that in humans is encoded by the ''UTP15'' gene. See also * Fibrillarin * Small nucleolar RNA U3 * RCL1 * RRP9 * UTP6 * UTP11L * UTP14A U3 small nucleolar RNA-associated prote ... References Further reading * * * * * * * * * * {{gene-X-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
