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UNC Lineberger Comprehensive Cancer Center
The UNC Lineberger Comprehensive Cancer Center is a cancer research and treatment center at the University of North Carolina at Chapel Hill. One of 52 National Cancer Institute-designated comprehensive cancer centers in the United States, its clinical base is the N.C. Cancer Hospital, part of the UNC Health Care system. UNC Lineberger is the only public NCI-designated comprehensive cancer center in the state of North Carolina. The current director is H. Shelton Earp III who succeeded current NCI director Norman Sharpless. History and name UNC Lineberger Comprehensive Cancer Center was established in 1975 with Joseph S. Pagano, Professor of Medicine and Microbiology at the University of North Carolina School of Medicine, as its founding director. It was named after the Lineberger family of Belmont, North Carolina, whose Lineberger Foundation provided the core funding for the center's first dedicated research and administrative building, completed in 1984. The cancer center was p ...
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Chapel Hill, North Carolina
Chapel Hill is a town in Orange, Durham and Chatham counties in the U.S. state of North Carolina. Its population was 61,960 in the 2020 census, making Chapel Hill the 17th-largest municipality in the state. Chapel Hill, Durham, and the state capital, Raleigh, make up the corners of the Research Triangle (officially the Raleigh–Durham–Cary combined statistical area), with a total population of 1,998,808. The town was founded in 1793 and is centered on Franklin Street, covering . It contains several districts and buildings listed on the National Register of Historic Places. The University of North Carolina at Chapel Hill and UNC Health Care are a major part of the economy and town influence. Local artists have created many murals. History The area was the home place of early settler William Barbee of Middlesex County, Virginia, whose 1753 grant of 585 acres from John Carteret, 2nd Earl Granville was the first of two land grants in what is now the Chapel Hill-Durham are ...
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Molecular Medicine
Molecular medicine is a broad field, where physical, chemical, biological, bioinformatics and medical techniques are used to describe molecular structures and mechanisms, identify fundamental molecular and genetic errors of disease, and to develop molecular interventions to correct them. The molecular medicine perspective emphasizes cellular and molecular phenomena and interventions rather than the previous conceptual and observational focus on patients and their organs. History In November 1949, with the seminal paper, "Sickle Cell Anemia, a Molecular Disease", in ''Science'' magazine, Linus Pauling, Harvey Itano and their collaborators laid the groundwork for establishing the field of molecular medicine. In 1956, Roger J. Williams wrote ''Biochemical Individuality'', a prescient book about genetics, prevention and treatment of disease on a molecular basis, and nutrition which is now variously referred to as individualized medicine and orthomolecular medicine. Another paper ...
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National Cancer Centers
National may refer to: Common uses * Nation or country ** Nationality – a ''national'' is a person who is subject to a nation, regardless of whether the person has full rights as a citizen Places in the United States * National, Maryland, census-designated place * National, Nevada, ghost town * National, Utah, ghost town * National, West Virginia, unincorporated community Commerce * National (brand), a brand name of electronic goods from Panasonic * National Benzole (or simply known as National), former petrol station chain in the UK, merged with BP * National Car Rental, an American rental car company * National Energy Systems, a former name of Eco Marine Power * National Entertainment Commission, a former name of the Media Rating Council * National Motor Vehicle Company, Indianapolis, Indiana, USA 1900-1924 * National Supermarkets, a defunct American grocery store chain * National String Instrument Corporation, a guitar company formed to manufacture the first reson ...
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Medical Research Institutes In North Carolina
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healin ...
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Federally Funded Research And Development Centers
Federally funded research and development centers (FFRDCs) are public-private partnerships that conduct research and development for the United States Government. Under Federal Acquisition Regulationbr>§ 35.017 FFRDCs are operated by universities and corporations to fulfill certain long-term needs of the government that "...cannot be met as effectively by existing in-house or contractor resources." While similar in many ways to University Affiliated Research Centers, FFRDCs are prohibited from competing for work. There are currently 42 FFRDCs, each sponsored by one or more U.S. government departments or agencies. History During World War II scientists, engineers, mathematicians, and other specialists became part of the United States massive war effort—leading to evolutions in radar, aircraft, computing and, most famously, the development of nuclear weapons through the Manhattan Project. The end of armed conflict did not end the need for organized research and development ...
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Cancer Organizations Based In The United States
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as '' Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of a ce ...
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Healthcare In North Carolina
North Carolina () is a state in the Southeastern region of the United States. The state is the 28th largest and 9th-most populous of the United States. It is bordered by Virginia to the north, the Atlantic Ocean to the east, Georgia and South Carolina to the south, and Tennessee to the west. In the 2020 census, the state had a population of 10,439,388. Raleigh is the state's capital and Charlotte is its largest city. The Charlotte metropolitan area, with a population of 2,595,027 in 2020, is the most-populous metropolitan area in North Carolina, the 21st-most populous in the United States, and the largest banking center in the nation after New York City. The Raleigh-Durham-Cary combined statistical area is the second-largest metropolitan area in the state and 32nd-most populous in the United States, with a population of 2,043,867 in 2020, and is home to the largest research park in the United States, Research Triangle Park. The earliest evidence of human occupatio ...
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List Of Nobel Laureates In Chemistry
The Nobel Prize in Chemistry ( sv, Nobelpriset i kemi) is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the 1895 will of Alfred Nobel, who died in 1896. These prizes are awarded for outstanding contributions in chemistry, physics, literature, peace, and physiology or medicine. As dictated by Nobel's will, the award is administered by the Nobel Foundation and awarded by the Royal Swedish Academy of Sciences. The first Nobel Prize in Chemistry was awarded in 1901 to Jacobus Henricus van 't Hoff, of the Netherlands. Each recipient receives a medal, a diploma and a monetary award prize that has varied throughout the years. In 1901, van 't Hoff received 150,782 SEK, which is equal to 7,731,004 SEK in December 2007. The award is presented in Stockholm at an annual ceremony on 10 December, the anniversary of Nobel's death. At least 25 laureates have received the Nobel Pr ...
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Aziz Sancar
Aziz Sancar (born 8September 1946) is a Turkish molecular biologist specializing in DNA repair, cell cycle checkpoints, and circadian clock. In 2015, he was awarded the Nobel Prize in Chemistry along with Tomas Lindahl and Paul L. Modrich for their mechanistic studies of DNA repair. He has made contributions on photolyase and nucleotide excision repair in bacteria that have changed his field. Sancar is currently the Sarah Graham Kenan Professor of Biochemistry and Biophysics at the University of North Carolina School of Medicine and a member of the UNC Lineberger Comprehensive Cancer Center. He is the co-founder of the Aziz & Gwen Sancar Foundation, which is a non-profit organization to promote Turkish culture and to support Turkish students in the United States. Early life Aziz Sancar was born on 8 September 1946 to a lower-middle-class family in the Savur district of Mardin Province, southeastern Turkey. His oldest brother Kenan Sancar is a retired brigadier general in the ...
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Joseph DeSimone
Joseph M. DeSimone (born May 16, 1964) is an American chemist, inventor, and entrepreneur who has co-founded companies based on his research, including the American 3D printing technology company, Carbon, of which he was CEO from 2014 until November 2019. Currently, DeSimone is the Sanjiv Sam Gambhir Professor of Translational Medicine in the Department of Radiology at Stanford University, where he is also Professor of Chemical Engineering. He joined the faculty at Stanford in 2020. In 2020, he was also elected to the board of trustees of the National Geographic Society. DeSimone previously held a joint appointment as the Chancellor's Eminent Professor of Chemistry at the University of North Carolina at Chapel Hill and William R. Kenan Jr. Distinguished Professor of Chemical Engineering at North Carolina State University. DeSimone has published over 350 scientific articles and has over 200 issued patents in his name with over 200 patents pending. He was awarded the 2020 Har ...
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Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic epidemiology, occupational epidemiology, screening, biomonitoring, and comparisons of treatment effects such as in clinical t ...
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