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UMLS Metathesaurus
The Unified Medical Language System (UMLS) is a compendium of many controlled vocabularies in the biomedical sciences (created 1986). It provides a mapping structure among these vocabularies and thus allows one to translate among the various terminology systems; it may also be viewed as a comprehensive thesaurus and ontology of biomedical concepts. UMLS further provides facilities for natural language processing. It is intended to be used mainly by developers of systems in medical informatics. UMLS consists of Knowledge Sources (databases) and a set of software tools. The UMLS was designed and is maintained by the US National Library of Medicine, is updated quarterly and may be used for free. The project was initiated in 1986 by Donald A.B. Lindberg, M.D., then Director of the Library of Medicine, and directed by Betsy Humphreys. Purpose and applications The number of biomedical resources available to researchers is enormous. Often this is a problem due to the large volume of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Compendium
A compendium (plural: compendia or compendiums) is a comprehensive collection of information and analysis pertaining to a body of knowledge. A compendium may concisely summarize a larger work. In most cases, the body of knowledge will concern a specific field of human interest or endeavour (for example: hydrogeology, logology, ichthyology, phytosociology or myrmecology), while a general encyclopedia can be referred to as a ''compendium of all human knowledge''. The word ''compendium'' arrives from the Latin word ''compendere'', meaning "to weigh together or balance". The 21st century has seen the rise of democratized, online compendia in various fields. Meaning, etymology and definitions The Latin prefix 'con-' is used in compound words to suggest, 'a being or bringing together of many objects' and also suggests striving for completeness with perfection. And ''compenso'' means balance, poise, weigh, offset. The entry on the word 'compendious' in the '' Online Etymology Dicti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
LOINC
Logical Observation Identifiers Names and Codes (LOINC) is a database and universal standard for identifying medical laboratory observations. First developed in 1994, it was created and is maintained by the Regenstrief Institute, a US nonprofit medical research organization. LOINC was created in response to the demand for an electronic database for clinical care and management and is publicly available at no cost. It is endorsed by the American Clinical Laboratory Association. Since its inception, the database has expanded to include not just medical laboratory code names but also nursing diagnosis, nursing interventions, outcomes classification, and patient care data sets. Function ''LOINC'' applies universal code names and identifiers to medical terminology related to electronic health records. The purpose is to assist in the electronic exchange and gathering of clinical results (such as laboratory tests, clinical observations, outcomes management and research). LOINC has two m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Syntactic
In linguistics, syntax () is the study of how words and morphemes combine to form larger units such as phrases and sentences. Central concerns of syntax include word order, grammatical relations, hierarchical sentence structure (constituency), agreement, the nature of crosslinguistic variation, and the relationship between form and meaning (semantics). There are numerous approaches to syntax that differ in their central assumptions and goals. Etymology The word ''syntax'' comes from Ancient Greek roots: "coordination", which consists of ''syn'', "together", and ''táxis'', "ordering". Topics The field of syntax contains a number of various topics that a syntactic theory is often designed to handle. The relation between the topics is treated differently in different theories, and some of them may not be considered to be distinct but instead to be derived from one another (i.e. word order can be seen as the result of movement rules derived from grammatical relations). Seq ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MEDLINE
MEDLINE (Medical Literature Analysis and Retrieval System Online, or MEDLARS Online) is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medicine, nursing, pharmacy, dentistry, veterinary medicine, and health care. MEDLINE also covers much of the literature in biology and biochemistry, as well as fields such as molecular evolution. Compiled by the United States National Library of Medicine (NLM), MEDLINE is freely available on the Internet and searchable via PubMed and NLM's National Center for Biotechnology Information's Entrez system. History MEDLARS (Medical Literature Analysis and Retrieval System) is a computerised biomedical bibliographic retrieval system. It was launched by the National Library of Medicine in 1964 and was the first large scale, computer based, retrospective search service available to the general public. Initial development of MEDLARS Since 1879, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Associative Entities
An associative entity is a term used in relational and entity–relationship theory. A relational database requires the implementation of a base relation (or base table) to resolve many-to-many relationships. A base relation representing this kind of entity is called, informally, an associative table. As mentioned above, associative entities are implemented in a database structure using associative tables, which are tables that can contain references to columns from the same or different database tables within the same database. An associative (or junction) table maps two or more tables together by referencing the primary keys (PK) of each data table. In effect, it contains a number of foreign keys (FK), each in a many-to-one relationship from the junction table to the individual data tables. The PK of the associative table is typically composed of the FK columns themselves. Associative tables are colloquially known under many names, including association table, bridge tab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hierarchy
A hierarchy (from Greek: , from , 'president of sacred rites') is an arrangement of items (objects, names, values, categories, etc.) that are represented as being "above", "below", or "at the same level as" one another. Hierarchy is an important concept in a wide variety of fields, such as architecture, philosophy, design, mathematics, computer science, organizational theory, systems theory, systematic biology, and the social sciences (especially political philosophy). A hierarchy can link entities either directly or indirectly, and either vertically or diagonally. The only direct links in a hierarchy, insofar as they are hierarchical, are to one's immediate superior or to one of one's subordinates, although a system that is largely hierarchical can also incorporate alternative hierarchies. Hierarchical links can extend "vertically" upwards or downwards via multiple links in the same direction, following a path. All parts of the hierarchy that are not linked vertically to one ano ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cluster Analysis
Cluster analysis or clustering is the task of grouping a set of objects in such a way that objects in the same group (called a cluster) are more similar (in some sense) to each other than to those in other groups (clusters). It is a main task of exploratory data analysis, and a common technique for statistics, statistical data analysis, used in many fields, including pattern recognition, image analysis, information retrieval, bioinformatics, data compression, computer graphics and machine learning. Cluster analysis itself is not one specific algorithm, but the general task to be solved. It can be achieved by various algorithms that differ significantly in their understanding of what constitutes a cluster and how to efficiently find them. Popular notions of clusters include groups with small Distance function, distances between cluster members, dense areas of the data space, intervals or particular statistical distributions. Clustering can therefore be formulated as a multi-object ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Semantic Network
A semantic network, or frame network is a knowledge base that represents semantic relations between concepts in a network. This is often used as a form of knowledge representation. It is a directed or undirected graph consisting of vertices, which represent concepts, and edges, which represent semantic relations between concepts, mapping or connecting semantic fields. A semantic network may be instantiated as, for example, a graph database or a concept map. Typical standardized semantic networks are expressed as semantic triples. Semantic networks are used in natural language processing applications such as semantic parsing and word-sense disambiguation. Semantic networks can also be used as a method to analyze large texts and identify the main themes and topics (e.g., of social media posts), to reveal biases (e.g., in news coverage), or even to map an entire research field. History Examples of the use of semantic networks in logic, directed acyclic graphs as a mnemonic to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medline
MEDLINE (Medical Literature Analysis and Retrieval System Online, or MEDLARS Online) is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medicine, nursing, pharmacy, dentistry, veterinary medicine, and health care. MEDLINE also covers much of the literature in biology and biochemistry, as well as fields such as molecular evolution. Compiled by the United States National Library of Medicine (NLM), MEDLINE is freely available on the Internet and searchable via PubMed and NLM's National Center for Biotechnology Information's Entrez system. History MEDLARS (Medical Literature Analysis and Retrieval System) is a computerised biomedical bibliographic retrieval system. It was launched by the National Library of Medicine in 1964 and was the first large scale, computer based, retrospective search service available to the general public. Initial development of MEDLARS Since 1879, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isa (computer Science)
In knowledge representation, object-oriented programming and design (see object-oriented program architecture), is-a (is_a or is a) is a subsumption relationship between abstractions (e.g. types, classes), wherein one class ''A'' is a subclass of another class ''B'' (and so ''B'' is a superclass of ''A''). In other words, type A is a subtype of type B when A's specification implies B's specification. That is, any object (or class) that satisfies A's specification also satisfies B's specification, because B's specification is weaker. The ''is-a'' relationship is to be contrasted with the ''has-a'' (''has_a'' or ''has a'') relationship between types (classes); confusing the relations ''has-a'' and ''is-a'' is a common error when designing a model (e.g., a computer program) of the real-world relationship between an object and its subordinate. The ''is-a'' relationship may also be contrasted with the '' instance-of'' relationship between objects (instances) and types (classes): se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
OMIM
Online Mendelian Inheritance in Man (OMIM) is a continuously updated catalog of human genes and genetic disorders and traits, with a particular focus on the gene-phenotype relationship. , approximately 9,000 of the over 25,000 entries in OMIM represented phenotypes; the rest represented genes, many of which were related to known phenotypes. Versions and history OMIM is the online continuation of Dr. Victor A. McKusick's ''Mendelian Inheritance in Man'' (MIM), which was published in 12 editions between 1966 and 1998.McKusick, V. A. ''Mendelian Inheritance in Man. Catalogs of Autosomal Dominant, Autosomal Recessive and X-Linked Phenotypes.'' Baltimore, MD: Johns Hopkins University Press, 1st ed, 1996; 2nd ed, 1969; 3rd ed, 1971; 4th ed, 1975; 5th ed, 1978; 6th ed, 1983; 7th ed, 1986; 8th ed, 1988; 9th ed, 1990; 10th ed, 1992. Nearly all of the 1,486 entries in the first edition of MIM discussed phenotypes. MIM/OMIM is produced and curated at the Johns Hopkins School of Medicine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Ontology
The Gene Ontology (GO) is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species. More specifically, the project aims to: 1) maintain and develop its controlled vocabulary of gene and gene product attributes; 2) annotate genes and gene products, and assimilate and disseminate annotation data; and 3) provide tools for easy access to all aspects of the data provided by the project, and to enable functional interpretation of experimental data using the GO, for example via enrichment analysis. GO is part of a larger classification effort, the Open Biomedical Ontologies, being one of the Initial Candidate Members of the OBO Foundry. Whereas gene nomenclature focuses on gene and gene products, the Gene Ontology focuses on the function of the genes and gene products. The GO also extends the effort by using markup language to make the data (not only of the genes and their products but also of curated attributes) machine read ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
