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UBB 1
UBB+1 is shorthand for Ubiquitin-B+1, a frameshifted mutant arising from the Ubiquitin B gene. UBB+1 is thought to arise from molecular misreading, a poorly understood process. Molecular misreading introduces dinucleotide deletions (e.g. ΔGA, ΔGU) into mRNA transcripts. These deletions are not present in genomic DNA. UBB+1 has been observed in the hallmarks of Alzheimer's disease, as well as other tauopathies and in polyglutamine diseases (e.g. Huntington's disease) but not in synucleinopathies Synucleinopathies (also called α-Synucleinopathies) are neurodegenerative diseases characterised by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibres or glial cells. There are three main types of synucle ... (e.g. Parkinson's disease). Since its discovery it has been shown ''in vitro'' and ''in vivo'' that UBB+1 inhibits the proteasome and gives rise to downstream effects (e.g. a behavioral phenotype; impaired contextual memory). In non-neuron ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Babeș-Bolyai University
The Babeș-Bolyai University ( ro, Universitatea Babeș-Bolyai , hu, Babeș-Bolyai Tudományegyetem, commonly known as UBB) is a public research university located in Cluj-Napoca, Romania. UBB has a long academic tradition, started by Universitas Claudiopolitana in 1581. It occupies the first position in the University Metaranking, initiated by the Romanian Ministry of Education and Research in 2016 Babeș-Bolyai University is the largest Romanian university with about 50,000 students. It offers study programmes in Romanian, Hungarian, German, English, and French (as well as a smaller number of programmes at the Master's level taught in Spanish, Italian, and Japanese). The university was named, following the fusion in 1959 of the Romanian and Hungarian-language universities in Cluj, after two prominent scientists from Transylvania, the Romanian bacteriologist Victor Babeș and the Hungarian mathematician János Bolyai. It is one of the five members of the ''Universitaria Consortiu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Bangka Belitung
University of Bangka Belitung (Indonesian: ''Universitas Bangka Belitung'', abbreviated UBB) is a public university in Bangka Belitung province, Indonesia. Located just outside the provincial capital of Pangkal Pinang in the Merawang subdistrict of Bangka Regency, it is the only public university (Indonesian: ''Perguruan Tinggi Negeri'') in the province. Formed by a merger of 3 higher education institutes in 2006 and formally inaugurated on 2010, the university currently hosts around 4,000 students with an annual intake of over 1,000 freshmen. It is the only university in the province which accepts students from the nationally administered SNMPTN system. History The province of Bangka Belitung separated from South Sumatra in 2000. Initially, the province had no major state universities, although there were multiple polytechnics and ''Sekolah Tinggi'' (Higher Education Institutes). On 12 April 2006, three such institutes: ''Politeknik Manufaktur Timah'' (Polman Timah), ''Sekolah ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Bío Bío
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ultimate Big Brother
''Ultimate Big Brother'' was the final series of the UK reality television programme '' Big Brother'' to air on Channel 4. The series was produced by Remarkable Pictures, a division of Endemol. ''Ultimate Big Brother'' was an All Star edition of the ''Big Brother'' series - featuring memorable housemates from previous series of ''Big Brother'', and ''Celebrity Big Brother''. A 24-hour live streaming service was also available via the ''Big Brother'' website as a fee-based service. The series ended with Brian Dowling winning the title of the "Ultimate Housemate" and the words "Big Brother will get back to you". Production The series was first announced during the launch night of the eleventh series of ''Big Brother''. The first trailer for ''Ultimate Big Brother'' was shown on 13 August 2010 during a live eviction episode of ''Big Brother''. On the same day, Channel 4 released a promo image for the series on the Big Brother website. The promo featured 15 of the previous 186 B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ultimate Breaks And Beats
''Ultimate Breaks and Beats'' (also commonly abbreviated as UBB) was a series of 25 compilation albums released from 1986 to 1991 by Street Beat Records edited by "BreakBeat Lou" Flores. Featured on the albums were tracks from 1966 to 1984 that included drum breaks. The albums found high popularity with hip hop producers, with the release of a new volume in the series usually leading to many various hip hop records featuring samples of the breaks. Re-releases of the LPs, some packaged in pairs for DJ scratching and mixing convenience, became available and are currently found in many record stores. CDs of some of the volumes may be found as well, including a 2-CD and DVD box set featuring nearly all of the tracks on the 25 albums. Releases Complete track listing, taken from Geocities.com and updated with performers' names, missing in the track lists of volumes SBR 499, SBR 500 and the first version of SBR 508. An asterisk after a track name indicates that the song was remix ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Usage Based Billing (UBB)
A data cap, often erroneously referred to as a bandwidth cap, is an artificial restriction imposed on the transfer of data over a network. In particular, it refers to policies imposed by an internet service provider in order to limit customers' usage of their services; typically, exceeding a data cap would require the subscriber to pay additional fees based on whether they have exceeded this limit. Implementation of a data cap is sometimes termed a fair access policy, fair usage policy, or usage-based billing by ISPs. U.S. ISPs have asserted that data caps are required in order to provide a "fair" service to their respective subscribers. The use of data caps has been criticized for becoming increasingly unnecessary, as decreasing infrastructure costs have made it cheaper for ISPs to increase the capacity of their networks to keep up with the demands of their users, rather than place arbitrary limits on usage. It has also been asserted that data caps are meant to help protect pay t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BBCode
BBCode ("Bulletin Board Code") is a lightweight markup language used to format messages in much Internet forum software, first introduced in 1998. The available "tags" of BBCode are usually indicated by square brackets ( _and_.html" ;"title="/code> and ">/code> and /code>) surrounding a keyword, and are parsed before being translated into HTML. Tags Implementation BBCode is typically implemented by applying a series of regular expression A regular expression (shortened as regex or regexp; sometimes referred to as rational expression) is a sequence of characters that specifies a search pattern in text. Usually such patterns are used by string-searching algorithms for "find" ... string-replace operations upon the input. Because regular expressions are limited in analyzing the structure of text input, this has the artifact that any non-hierarchical BBCode input will be transformed into invalid non-hierarchical HTML without error. Applying traditional parsing techniques ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ubiquitin B
Ubiquitin is a protein that in humans is encoded by the ''UBB'' gene. Function Ubiquitin is one of the most conserved proteins known in eukaryotic organisms. Ubiquitin is required for ATP-dependent, non-lysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein ( UBB+1) has been noticed in patients with Alzheimer's disease, Down syndrome, other tauopathies (e.g. Pick's disease) and polyglutami ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Unbibium
Unbibium, also known as element 122 or eka-thorium, is the hypothetical chemical element in the periodic table with the placeholder symbol of Ubb and atomic number 122. ''Unbibium'' and ''Ubb'' are the temporary systematic IUPAC name and symbol respectively, which are used until the element is discovered, confirmed, and a permanent name is decided upon. In the periodic table of the elements, it is expected to follow unbiunium as the second element of the superactinides and the fourth element of the 8th period. Similarly to unbiunium, it is expected to fall within the range of the island of stability, potentially conferring additional stability on some isotopes, especially 306Ubb which is expected to have a magic number of neutrons (184). Despite several attempts, unbibium has not yet been synthesized, nor have any naturally occurring isotopes been found to exist. There are currently no plans to attempt to synthesize unbibium. In 2008, it was claimed to have been discovered in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Union Bordeaux Bègles
Union Bordeaux Bègles (; oc, Union Bordèu Begla) is a French rugby union team playing in the Top 14, the first level of the country's professional league system. They earned their Top 14 place by winning the promotion playoffs that followed the 2010–11 season in the second-level Rugby Pro D2. Upon promotion to the Top 14 in 2011, they were assured a place in the European Challenge Cup. In 2015, they earned their European Champions Cup place, after winning the European playoffs against Gloucester Rugby in Worcester. They were founded in 2006 as a result of a merger between two Bordeaux clubs, Stade Bordelais and Club Athlétique Bordeaux-Bègles Gironde. They wear claret (in French: ''bordeaux'') and white. They are based in Bordeaux (Nouvelle-Aquitaine), and play at the Stade Chaban-Delmas. The two teams which amalgamated cumulated nine championship titles of France: seven for the Stade Bordelais and two for the Club Athlétique Bordeaux-Bègles Gironde. Since 2006 and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United Bulgarian Bank
United Bulgarian Bank (UBB) is one of the leading Bulgarian commercial banks. It is the first and largest banking consolidation project in Bulgaria, accomplished through the merger of 22 state-owned commercial banks throughout the country. UBB was established on 30 September 1992. The Bank manages assets, worth approximately BGN 6.6 billion and renders services to its clients via nearly 200 branches and banking structures throughout the country. The core business of UBB is being supported through the activity of its subsidiaries, UBB Asset Management, UBB Factoring and UBB Insurance Broker. History United Bulgarian Bank is the first large-scale project for banking consolidation in Bulgaria. It was founded on 30 September 1992 through the merger of 22 regional state-owned banks – Botevgradska Commercial Bank AD, Vrachanska Commercial Bank AD, Gabrovska Commercial Bank AD, Commercial Bank Doverie AD, Commercial Bank Elhovo AD, Commercial Bank Iskar AD, Kardzhaliyska Commercial Bank ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Usedomer Bäderbahn
The Usedomer Bäderbahn (UBB) with its head office in Heringsdorf, northeastern Germany, is a 100 percent-owned subsidiary of the German national railway, Deutsche Bahn and the owner and operator of the railway network on the island of Usedom Usedom (german: Usedom , pl, Uznam ) is a Baltic Sea island in Pomerania, divided between Germany and Poland. It is the second largest Pomeranian island after Rügen, and the most populous island in the Baltic Sea. It is north of the Szczec ... as well as the Züssow–Wolgast and Velgast–Barth lines. It refers to all the lines on which it runs services – i.e. Züssow–Stralsund–Velgast – as the ''Vorpommernbahn'' or “West Pomeranian Railway”. The UBB is a member of the Fare Association of Federal and Non-Federal Railways in Germany (''Tarifverband der Bundeseigenen und Nichtbundeseigenen Eisenbahnen in Deutschland'') or TBNE, albeit without voting rights, because it belongs to Deutsche Bahn. Network Current service ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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